Natural product chemistry

Dr J White

Identify different natural products

Synthesise your own perfume

• What is your impression of a chemist?

• Write down one job that a chemist does?

Natural products

• What are they?• Chemicals found in living things

• Where can you find them?

• What can you do with them?

Where can you find them?

• Plants (spearmint), animals, bacteria

carvone

Marine Natural products

• Gorgonian octacoral• Octalactin A

How do you get them?

What you do with them?

Fragrances

Pharmaceuticals

Food additives

Task

• Here are a mixture of natural products with common fragrances

• Match the fragrance to the natural product

What does the organic chemist do?

• Marine life have only a small amount of the active component.

• Pharmaceutical companies want to make these compounds – Big scale– Cheap– Safe– Improve on nature

Building

• We have to look at the target structure and create a strategy to build it.

• Check our big recipe book of reactions• Building a car or baking a cake.

Task

• Watch video clip from bbc senses• http://www.youtube.com/watch?v=7jYtpOlKs

TI• How bad was the smell?

• We will make our own brand of fragrance

What you have to do

• Safety• Wear gloves & safety glasses• Mix different ratios of • base notes least fragrance• Middle notes • Top notes most volatile• We will judge how good the fragrance is.

Top

Eucalyptus

Lemon

Middle

geranium lavender

BottomJasmine

Patchouli

Ylangylang

Bottom

Jasmine

Patchouli

Ylangylang

Middle

geranium

lavender

Top

Eucalyptus

Lemon

Chemistry

Physics Biology

BioChemistry

Biophysics

Chemical physics

They look more like this

Chemists