NETWorks Spring 2008

Embed Size (px)

Citation preview

  • 8/7/2019 NETWorks Spring 2008

    1/25

    THE SCIENCEENGINEERING &TECHNOLOGYMAGAZINE FORNORTH EASTENGLAND

    ISSUE 5SPRING2008

    MEDICAL

    DEVICES AND

    INSTRUMENTATION

    ISSN 1753-6677

    HYBRID

    INTELLIGENT

    SYSTEMS

    SPACE

    TECHNOLOGY

    PROVIDES

    COSMIC VISION

    CANCER TEST

    BREAKTHROUGH

  • 8/7/2019 NETWorks Spring 2008

    2/25

    Medical devices and instrumentation are fields of science that affect all of us Im

    sure we all remember sitting in bed ill as a child with a mercury thermometer in

    our mouth. Nowadays that thermometer looks very different. What is really

    intriguing is how expertise in one area is applied to another: the Durham University

    Centre for Advanced Instrumentation develops instruments for telescopes that

    compensate for the blurring effects of the Earths atmosphere. Theyre now

    applying that expertise to illnesses that cause our vision to become blurred.

    Then there is Seaward, an instrumentation company in Peterlee that supplies

    every single Air Force base in the US, and is now turning its attention to medical

    applications.

    Unlike some scientific endeavours, medical devices are right here right now

    even the most cutting edge research in the regions universities is pretty close to

    market. And in NETWorks some of the most successful companies in the region

    tell us whats already here in this sector, which is flourishing at the moment.

    The team at Cels has been invaluable in its support for this issue - Im delighted to

    announce that Mike Asher, CEO of Cels, will be the guest editor of the next issue

    of NETWorks which will feature biotechnology. Mike will be the first guest editor of

    NETWorks and we all look forward to welcoming him to the NETWorks team.

    CJ

    Contributors

    Mike ParkerMike spent a decade in national, regional and local journalism culminating in his

    appointment as Business Editor of The Northern Echo. He was named North East

    Business Writer of the Year before joining the North East Chamber of Commerce

    where he was responsible for a threefold increase in publicity and press coverage.

    Andrew WoodAndrew has lived all over the world working and writing for the process industries,

    including a stint as head of global corporate media relations for Dow Chemicals.

    Andrew was editor-in-chief of Chemical Week, the world's leading chemical

    industry magazine for 10 years before relocating back to the North East.

    Editor Catherine Johns Scientific Advisor Professor John AnsteeDeputy Editor Rob Heslop

    NETWorks is published by Distinctive Publishing Ltd24 Lancaster Street, Summerhill, Newcastle Upon Tyne NE4 6EUTelephone 0191 298 3571

    Managing Director Barrie Miller Creative Director Martin WilliamsonSales Director John Neilson

    For all enquiries including editorial, subscription and advertising please contactDistinctive Publishing.

    With thanks to all our contributors.

    Front cover image - Northumbria University

    NETWorks is supported by NETPark www.uknetpark.net

    Letter from the Editor

    01

    What is reallyintriguing is

    how expertisein one area is

    applied to

    another

  • 8/7/2019 NETWorks Spring 2008

    3/25

    08

    03 05

    10

    14 18

    24 27

    30 32

    3634

    NSTARNEW CONCEPTS

    IN MEDICALINNOVATION

    SPACETECHNOLOGY

    PROVIDES COSMICVISION

    ROCKET MEDICALCUSTOMER FOCUS

    PAYS DIVIDENDS

    ABOUT NETPARK

    NHS INNOVATIONSNORTH

    ASSIST CANCERTEST

    BREAKTHROUGH

    CELS

    AIDING THE AGEING

    PATENTS ADVICECENTRE

    INTELLECTUALPROPERTY FOR

    SMALL BUSINESSES

    UNIVERSITY OFSUNDERLAND

    HYBRIDINTELLIGENT

    SYSTEMS

    NORTHUMBRIAUNIVERSITY

    A VALUABLE SHOT

    IN THE ARM

    CELSAWARDS

    RECOGNISEHEALTHCARE

    TALENT

    HART BIOLOGICALSLEADING THE WAY

    IN MEDICALDIAGNOSTICS

    06

    12

    20

    28

    33

    38

    SEAWARDACHIEVING

    SUCCESS INTESTING

    CELSBUSINESS FOR LIFE

    40 42

    UKTILOOK BEFORE

    YOU LEAP

    CELSREGIONAL

    FINALISTS SWEEPNATIONAL AWARDS

    43APPLIED

    NEURODIAGNOSTICSTHE EYES HAVE IT

    FOR VISUALRECOGNITION

    SPECIALISTS

    HELIOSWHEN ONE SIZE

    DOES NOT FIT ALL

    TEESSIDEUNIVERSITY

    CHANGING THELIVES OF THE

    ELDERLY

    SRGNE SCIENCE

    SALARIES RISING

    NEWCASTLEUNIVERSITY

    BIOMEDICAL ANDBIOMOLECULAR

    SCIENCES

    NEW CONCEPTS IN

    MEDICAL INNOVATIONNorthStar Equity Investors (NSEI) is helping exciting

    new concepts in medical innovation become

    commercial success stories. NSEI manages the

    10m Proof of Concept Fund, designed to catalyse

    new technology, and the 23m Co-Investment Fund

    which provides equity of between 100,000 and 1M

    to help fast growing companies reach their

    potential.

    The Proof of Concept Fund was instrumental in UK

    Haptics development of prototype software that has

    evolved into Virtual Veins, a leading edge 3D virtual

    reality training software for the nursing profession.

    Virtual Veins provides state of the art training in

    venepuncture, enabling nursing students to perfect their

    technique without risk to patients. UK Haptics has gone

    on to secure substantial private investment and close its

    first sale.

    The 500,000 contribution from the Co-Investment

    Fund towards a 1.4m funding round will help Teesside

    based Femeda launch its new female health products

    into clinics nationwide. Femeda Ltd has developed a

    revolutionary disposable device that will allow thousands

    of women to overcome the suffering caused by urinary

    incontinence.

    Based in Cramlington, Applied Neurodiagnostics Limited

    secured 590,000 from NorthStar Equity as part of a

    1.2m investment to pioneer medical devices that use

    revolutionary eye tracking and pupil measuring devices

    as base technology. The company is set to launch the

    PLR60, a new device set to improve the way optometrists

    determine the presence or absence of damage to the

    retina as part of a patients routine eye test.

    The number of companies to receive NSEI support is

    growing. Over 131 firms have been recipients of Proof of

    Concept Fund investments, while the Co-Investment

    Fund has backed 23 high growth ventures. NSEI is

    always keen to hear from ambitious entrepreneurs with

    a keen eye for commercial success.

    Gary Todd

    of UK Haptics

    and Lord

    Robert Winston

    DURHAMUNIVERSITY

    THIGH BONESCONNECTED TO

    THE HIP BONE

  • 8/7/2019 NETWorks Spring 2008

    4/25

    This is an opportune time for NETWorks to review the sector of medical

    devices and instrumentation: its predicted that companies in this sector are

    likely to outperform the broader stock market in 2008 with a 9% growth

    forecast for the coming year.

    Some of the most interesting venture capital deals signed over the past year inEurope have involved companies in this sector, and annual medical devicesoutput in 2007 has been estimated at 71 billion.

    Globally, Europes medical devices manufacturing market is the second largest,and with an ageing population leading to increased spending on healthcare andwith health consciousness moving up the political agenda, it seems reasonableto expect continued expansion.

    Last autumn, a list of key technologies named in a Council for Science andTechnology (CST) report as being vital to Britain's economic future included

    medical devices for improving health care and the prevention, diagnosis andtreatment of disease. Of course, you cant diagnose, monitor and treat withoutdeveloping analytical technologies and manufacturing the appropriate devicesand instruments.

    New technologies, new tools, methodologies and processes can make themanufacture of existing products more efficient and new products possible.Improved processes can lead to bigger production volumes, which in turn canlower unit costs.

    Its a global business - one where we compete with companies all over theworld. One interesting example I came across recently was the ChanghuatCorporation Berhad in Malaysia. Previously, the Corporation had focussed oncomponents for the automotive and electronic appliances markets. Now, toremain competitive in the plastic injection moulding industry, it has adopted along-term strategy which will see it introduce a range of disposable medicaldevices products.

    I would encourage you to read on and learn more about whats happening in theregions universities and Centres of Excellence, and the pioneering work beingcarried out by innovative North East companies.

    Comment

    from

    Professor

    John

    Anstee

    CUSTOMER

    FOCUS PAYS

    DIVIDENDS FOR

    ROCKET MEDICALBased in Washington, Tyne & Wear, Rocket Medical isan award-winning designer and manufacturer ofmedical devices.

    Founded in 1964 it concentrates on a number of core

    areas cardiothoracic, infertility, oncology and womens

    healthcare.

    High grade clean rooms provide for the assembly of an

    increasingly wide range of complex products Rocket

    Medical currently offers 1900 different product lines

    and with a customer focused ethos, the company is

    always open to new product ideas from customers.

    Rocket Medicals products include operating theatre

    consumables, cardiac and thoracic drainage catheters,

    chest drainage systems, Oocyte harvesting systems

    and embryo transfer catheters for IVF, and a range of

    fetal monitoring devices for labour wards.

    Since its inception, the company has assembled a

    remarkable range of manufacturing skills these include

    large scale injection moulding, complex insert moulding,

    extrusion, CNC punching and drilling, and RF/Induction

    polymer manipulation.

    With its own design team utilising the latest in CAD

    software and rapid prototyping systems, Rocket

    Medical succeeds in manufacturing well designed

    products of the highest quality, delivered on time and at

    a sensible price.

    Using external specialist companies and universities

    allows it to expand its capabilities and it retains a flexible

    approach that encourages product customisation.

    Nominated in seven categories in the 2007 Best Factory

    Awards, Rocket Medical carried off, for the second time,

    the Innovation Award and now the Most Improved

    Factory award to add to a previous Best Small

    Company award.

    To find out more visit www.rocketmedical.com

    05

    John is Emeritus Professor of Biological Sciences,

    Durham University and the Scientific Director for

    NETPark. Until his retirement in July 2004, he held the

    position of Pro-Vice-Chancellor and Subwarden at

    Durham University.

    He is a graduate of the University of Nottingham (B.Sc., Ph.D.), a

    Fellow of the Royal Entomological Society, a Fellow of the Zoological

    Society of London and a Member of the Society of Experimental

    Biology. He holds directorships in a number of companies associated

    with scientific research and Technology Transfer including the Centre

    for Process Innovation (CPI) Ltd, the Centre of Excellence for Life

    Sciences (CELS) Ltd, the Company of Biologists Ltd and is a former

    Associate Director of County Durham Development Company. He is a

    Deputy Lord-Lieutenant for County Durham.

    PROFILE - JOHN ANSTEE

  • 8/7/2019 NETWorks Spring 2008

    5/25

    Mike Asher is CEO of Cels and has over 20 yearsexperience in business, of which 14 have beenspent running international science and healthcare-related businesses.

    Mikes experience in the health industry includesworking on a consultancy basis with the NHS todevelop a strategy aimed at delivering greatercommercial focus to its procurement activities.Before that he ran medical diagnostics companyDrew Scientific Group PLC which specialised in

    diabetes and haematology testingsystems. As Chief ExecutiveOfficer he achieved sales growthof 400 per cent from 2.5 to 12.5million in just five years. Mike hasalso held positions with healthcarecompany Coulter Electronics Limited, where hesuccessfully developed operations and customerservices internationally.

    PROFILE MIKE ASHER

    aged over 65 in the UK has grown by a staggering

    31%, from 7.4 to 9.7 million, while the over 85s have

    grown to a record 1.2 million. In the North East the last

    three years alone have seen a 2% increase in the

    number of over 60s. In order to address this significant

    demographic change, Cels has joined the ActiveAge

    programme as a strategic partner. This organisation

    aims to draw together international experts, industry

    innovators, thought-leaders and frontline practitioners

    from the public and private sectors to discuss policies,

    strategies and practical solutions to ageing related

    problems.

    Incubation, stem cells, assistive technologiesCels has

    packed a lot into 2007 can they keep up the pace for

    2008? Youd better believe it, says Mike, We have a

    remarkable team of people in place at Cels and a

    healthcare sector that is leaping from strength to

    strength.

    Find out more in the next issue of NETWorks. To find

    out more about the healthcare business opportunities

    available in the North East visit www.celsatlife.com

    The Business for Life Awards are featured on page 30.

    This is an exciting time for the life science and healthcare

    markets, both in the North East and nationally, and Cels

    continues to demonstrate remarkable achievements in

    this field.

    Our strategy is to support businesses, work with the five

    North East universities, as well as associated outstanding

    academic research centres and the NHS in the region

    explains Mike, and that remains at the heart of

    everything we do, we are here to ensure that the regions

    healthcare economy can compete with the best in the

    world. If I had to pick out some highlights of last year I

    would choose the opening of the GMP facility, our new

    incubation facilities, the RegeNer8 programme, the Active

    Age Summit and the first ever Business for Life Awards.

    The North East science community recently welcomed

    Sir David King, the governments Chief Scientific Adviser

    to the region, marking the formal opening of a new

    facility designed and built to produce stem cells to

    current Good Manufacturing Practices (cGMP) standard.

    The new facility will allow academics and clinicians to

    produce biologics at the standard required for use in the

    treatment of patients. Although a number of other

    universities and NHS trusts in the UK are building similar

    facilities, this is one of the largest. It is unique in that it

    allows scientists to produce treatments based on both

    embryonic and adult stem cells in separate areas. Sir

    David King commented These facilities are not just

    critical to the wealth of our economy but also the future

    health of ours and other nations.

    Whilst in the region Sir David King also officially opened

    state-of-the art business incubation facilities, Cels at

    Newcastle, at Newcastle University, designed

    specifically to help develop scientific ideas and early

    stage life science businesses identified as having

    significant commercial potential. As well as providing

    assistance on aspects of early stage business, such as

    funding, marketing, business planning and

    commercialisation, Cels has a variety of on the ground

    projects to support all healthcare businesses.

    At a regional level, Cels continues to work in close

    partnership with the North East Stem Cell Institute

    (NESCI) to draw together stem cell expertise throughout

    the region, with the aim of converting stem cell research

    into cost effective and ethically robust solutions to

    combat degenerative and other diseases.

    Cels continues to advance this area, more recently

    helping to launch a virtual centre called RegeNer8, set

    to bring together the work of top scientists throughout

    the North of England to further their work in regenerative

    medicine. Cels, alongside Leeds-based BITECIC

    (Biomaterials and Tissue Engineering Centre of Industrial

    Collaboration), has played a pivotal role in this project,

    funded by the Northern Way, the consortium of the

    three Northern development agencies including One

    NorthEast.

    RegeNer8, The N8 Centre for Translational Regenerative

    Medicine is the focus of collaboration between industry,

    clinicians and academics at the norths eight most

    research-intensive universities, known as the N8. Cels

    has provided RegeNer8 with business and marketing

    support to translate its world-class expertise into new

    regenerative medicine products and therapies.

    Another area of healthcare that Cels focuses on is

    assistive technology. The first annual ActiveAge Summit

    took place in Newcastle in November, and it brought

    together internationally renowned experts on ageing,

    who joined together to discuss how technology can be

    used to help sustain a high quality of life for an

    increasingly ageing society. This is an important issue

    because over the last 35 years the number of people

    Cels has been tasked by One NorthEast to stimulate a year on year increase in the

    economic contribution of the life science and healthcare markets to the region of

    1.2 billion by 2015. NETWorks spoke to Mike Asher, Cels Chief Executive Officer,

    about how Cels is driving growth in this sector.

    BUSINESSFOR LIFE INNORTH EASTENGLAND

    07

  • 8/7/2019 NETWorks Spring 2008

    6/25

    AIDING THEAGEING

    Over the last 5 decades there has been a 45% increase in the number of people aged over 50. By 2031 this is

    projected to rise by another 36% according to the Office of National Statistics. The world is facing the challenge

    of a rapidly ageing population, with increasing cost and manpower pressures on healthcare and social care

    providers. The UK currently leads the world in the use of technology to support older people, but new

    applications of technology are needed if the true benefits are to be realised. The Cels Assistive Technology Lab

    (ATL) project seeks to build on the North Easts existing academic and industrial strengths in this area and to

    position the region as the leading region in the UK in the emerging field of gerontechnology.

    09

    Provision of effective care for older people requires

    involvement by a large number of stakeholders; older

    people themselves, clinicians and health professionals,

    care workers and occupational therapists, informal carers

    and family members, technology providers and product

    designers, health economists and policy makers. Through

    the ATL project, Cels is building a powerful network of

    stakeholders, both within the North East and beyond, to

    develop product and service solutions that are truly

    effective.

    At the policy/strategy level, Cels is the strategy partner

    within ActiveAge, a research network of private and public

    organisations interested in the impact of the ageing

    population. Key areas of focus for ActiveAge research and

    ATL include:

    1. Mobility both personal mobility and public and

    private transport. Staying mobile and socially active is key

    to a healthy old age, but becomes increasingly challenging

    with the impact of chronic age-related conditions.

    Case Study 1 Keeping In Touch Everyday (KITE)

    This is a user-centred design project in collaboration with

    Newcastle University involving people with dementia andtheir carers. The aim is to enable them to continue to

    undertake normal activities (driving, walking and exercise)

    in safety using GPS/GPRS technology. This project

    includes social scientists, computer scientists, product

    designers, technology SMEs and local user groups. The

    involvement of people with dementia and their carers in a

    user-centred design project is challenging and is a unique

    approach to the support of people with this chronic

    condition.

    2. Wellness putting the focus onto preventative

    healthcare and maintaining wellbeing, rather than treating

    chronic conditions.

    Case Study 2 Advanced interactive Digital Exercise

    Prescription Technologies (AiDEPT)

    Cels is supporting a project involving a local SME and

    researchers at the University of Teessides Department of

    Sports Science. The team has developed a prototype

    system combining an exercise bike, heart rate monitor

    and immersive computer game to promote safe exercise

    for people under exercise referral programmes. The

    game is used to engage users and promote programme

    adherence. The system is currently being used in a real-

    world user trial within a commercial gym environment.

    3. Work the combination of longer life expectancies and

    declining birth rates in recent decades will fundamentally

    change the proportion of people in work compared to

    those in retirement.

    Case Study 3 Research Report

    Business and technology consultants within Cels have

    researched and published Technology To Support the

    Ageing Global Population 2007 to 2027 - created to

    research and understand the issues of wide-scale

    adoption of Assistive Technology solutions, considering

    barriers such as end-user design, technology challenges,

    sustainable business and service models and the issues

    of infrastructure.

    4. Community social inclusion is widely believed to be

    another key factor in ageing successfully. The risk of socialisolation grows as we age, especially with the loss of a

    spouse and other friends. Social isolation is as much a risk

    in urban environments as it is in sparsely populated rural

    areas.

    Case Study 4 Circles of personal movement

    Cels is working with researchers in the People And

    Communications Technology Lab (PACTLab) group

    within the School of Psychology at Northumbria University.

    The project is using advanced GPS/GPRS movement

    tracking to record the movement of a group of older

    volunteers over time. The research project seeks to

    understand the relationship between wellbeing,

    geographic areas of movement, levels of activity and

    degrees of social inclusion by mapping movement

    between necessary trips (e.g. to the GP surgery) and

    leisure trips.

    The next phase of the ATL project will continue with this

    work and will extend to developing and co-ordinating

    larger-scale community-based trials of telehealth and

    telecare systems, working with partners at the Institute of

    Ageing & Health at Newcastle University, Newcastle City

    Council, County Durham PCT and the NHS.

    Cels is also widening its network of collaborators, forging

    links with major players in the field of ageing and

    technology research, including MIT AgeLab, the University

    of Florida and the Continual Health Alliance (an

    international association of over 100 major technology

    companies, led by Intel). Cels has also been instrumental

    in the establishment of the Assisted Living Innovation

    Platform programme by the UK governments Technology

    Strategy Board and aims to be actively involved in

    projects funded by that programme.

    Through all of these activities Cels ATL has gained a deep

    understanding of the challenges posed by an older

    population, the difficulties faced by older people, and of

    the potential of technology to address these challenges.

    This is complementing the development of the Campus

    for Ageing and Vitality within the Newcastle Science City

    programme, positioning Newcastle and the North East at

    the forefront of a major new global industry sector.

    For further information on ATL visit www.celsatlife.com

    or call 0191 211 2560

  • 8/7/2019 NETWorks Spring 2008

    7/25

    It was exciting to see the activity of the regions

    healthcare sector celebrated at the Cels Healthcare

    Networks Business for Life Awards in November. Of

    note was the fact each of the five category winners was

    a manufacturing company, reminding us just how

    valuable this traditional sector is to the North East. The

    winners on the night suggest there is very little

    traditional about modern manufacturing.

    These high performing companies are as likely to be

    involved with digital networks, product data

    management and rapid prototyping as they are with

    installed plant and material processing. Increasingly,

    companies that count themselves as manufacturers are

    actually venturing into the complex terrain of a product-

    service mix where the focus for the business is shifting

    to improving innovation and customer service.

    This places new demands on companies to explore the

    opportunities to develop new products and services that

    address changes in the external business environment.

    New legislation and regular changes in the way the

    healthcare markets are structured, means that tracking

    and responding to these opportunities needs

    commitment to invest in expanding R&D activities.

    Two of the five winning companies at the Business for

    Life Awards are engaged in significant R&D programmes

    and deserve enormous credit for recognising howimportant R&D is to sustainable growth. Both Applied

    Neurodiagnostics Ltd and UK Haptics, winners in the Start-

    Up and Innovation categories respectively, are actively

    engaged with the Cels/Northumbria University InSTeP

    program. InSTeP ensures that their innovative products,

    although brand new, are tried-and-tested for market.

    Funded by One NorthEast and the European Regional

    Development Fund, InSTeP is managed by Cels to

    provide a unique collaboration of regional healthcare,

    engineering, product development and design

    professionals. The delivery of InSTeP client projects is

    led by Northumbria Universitys Centre for Design

    Research and also brings in other regional partners

    including C2M (UK) Ltd, INEX, Kinneir Dufort, NHS

    Innovations North and Newcastle Universitys Resource

    Centre for Innovation & Design.

    According to Dr Mark Jarvis, InSTeP Programme

    Manager at Cels, InSTeP is having a real impact on

    North East companies developing new products in the

    healthcare sector, The initiative has enabled innovative

    concepts to become truly market-led products that will

    make a significant contribution to the growth of the

    regional economy. If companies are to maximise the

    market potential of medical and healthcare products,

    user focused design is of central importance. InSTePs

    unique multidisciplinary development model provides a

    high level of added-value to companies in the North

    East by the application of design combined with end-

    user consultation and sector knowledge. This is clearly

    borne out by the experiences of the companies

    involved.

    Case Study - UK Haptics Ltd: Medical Device Adaptor

    for Haptic Training Suite

    The InSTeP initiative allowed us to make tangible a vital

    part of our device, and has really fast-tracked the

    development of this product.

    Gary Todd, Managing Director, UK Haptics Ltd

    The Brief

    InSTeP was approached by UK Haptics to develop a

    medical instrument adaptor for a new medical training

    and evaluation tool. It enables users wearing 3D glasses

    to manipulate a Haptic Pen in the real world, whilstseeing this as a medical tool or piece of equipment in

    the virtual environment. Users can practice and be

    assessed at performing clinical procedures, with the

    Haptic Arm providing real physical feedback to give the

    sensation of true interaction with the virtual environment.

    The Project

    UK Haptics was funded through InSTeP to work with

    the Centre for Design Research to develop a new

    multifunctional adaptor. It would allow the user to hold

    and manipulate real medical tools whilst performing the

    virtual procedure. Though initially focussed on the

    attachment of cannular needles, the design was future-

    proofed to enable the attachment of as-yet-unspecified

    devices. InSTeP liaised with partners to produce a rapid

    prototype of the solution, enabling evaluation in the

    context of UK Haptics current system.

    A VALUABLE SHOT

    IN THE ARM FOR

    THE HEALTHCARE

    SECTORMatthew Lievesley from Northumbria Universitys Centre for Design Research

    looks at the impact of design in an increasingly successful sector.

    The Outcome

    The speed of development and the provision of a

    physical prototype enabled UK Haptics to progress

    distribution talks with potential international partnerswhilst attending a leading US-based haptic conference.

    The system has now been sold to a number of

    commercial and research clients, while the adaptor

    prototype is currently undergoing initial user and safety

    testing.

    To find out more about the InSTeP initiative and

    opportunities to fund development projects, contact Mark

    Jarvis at Cels on 0191 211 2606 or Bruce Watson at the

    Centre for Design Research on 0191 243 7063.

    The Centre for Design Research is a fifteen-strong

    multidisciplinary design team at Northumbria University

    which works with both private and public sectors to

    develop better products and services.

    For more information about Applied Neurodiagnostics

    Ltd, see page 43.

    11

  • 8/7/2019 NETWorks Spring 2008

    8/25

    Its the simplest things that can make a difference to

    peoples quality of life a new fixing that can work on

    fractures of brittle bones, even an improved carpet

    underlay that prevents injuries from falls in the first

    place. The practical application of our research into

    products that improves peoples well-being and saves

    our health service money is one of the most rewarding

    things for the team here at the University of Teesside.

    This reward has been the result of intensive studies into

    hip biomechanics, leading to a great advancement in

    the understanding of how bones can fracture but then

    repair themselves. A natural progression from this

    activity has been the move into other important research

    topics such as minimising this type of damage in the

    elderly due to falls.

    Currently the team is working with Leyland Rubber

    Components Ltd in Lancashire to secure a Knowledge

    Transfer Partnership programme to test different

    materials that could minimise the risk of fractures when

    the elderly fall.

    The NHS invests large amounts of money treating hip

    fractures in elderly people caused by falls. In 1994,60,000 patients were treated in the UK at a cost then of

    742 million and this is predicted to rise to 117,000 by

    2016. Overall, over 50% of fractures are due to falls

    from tripping at home, which rises even further for

    patients older than 75 years of age. Slippery flooring

    and unsuitable footwear are major factors contributing

    to the onset of fractures in the home.

    This is backed up by a report by the Royal College

    Physicians published in 1989, which stressed that even

    a small percentage reduction in the incidence of hip

    fractures would save several million pounds in health

    care costs. Unfortunately conventional underlays offer

    poor energy absorption when the elderly fall, and vinyl

    floors are even poorer at reducing the energy that may

    fracture a hip in an elderly person falling onto it.

    Our job is to help test other materials that provide a

    much higher energy absorption and which can be

    fabricated as underlays. Usually, the testing of these

    materials is done with flat conventional impact test

    machines but we developed a computer model from

    anatomical data to simulate patients falling onto different

    materials of different thickness to ascertain the most

    appropriate mechanical properties. We have an existing

    test rig to validate the peak force values, energy

    absorption, HIC derived from an accelerometer and the

    compression set properties, and to design a

    flooring/underlay area and measure the traction forces

    of pushing wheelchairs and hoists.

    Another innovation that will help prevent fractures is the

    design of a new hip protector attached to the skin.

    The current designs of hip protector pads are

    incorporated into garments - compliance with

    continuous wearing of these garments is extremely poor.

    The new design will encompass the most mechanically

    desirable features and entail the production of a

    composite layered shaped pad that would be attached

    by adhesive on the skin on both hips under clothing.

    This type of pad will stay in the correct position for up toa week, it will need no maintenance, will be waterproof

    and will reduce the likelihood of a hip fracture.

    The SDMA (Surgical Dressings Manufacturers

    Association) recommended the University of Teesside

    mechanical test rig should be used as the standard

    against which all hip protectors manufactured in Europe

    are compared, despite stiff competition from various

    groups originating from Italy, Switzerland and Germany.

    The Test Rig has now been commissioned, and a

    commercial service has been provided to manufacturers

    who wish to test their hip protectors using the standard

    test rig and procedures.

    In order to help understand the nature of the

    biomechanical problem, a deep understanding of the

    fracture process is required, and this has been achieved

    via the teams link up with respected medical

    practitioners and scientists. One of the key achievements

    of the team has been the linking together of this medical

    research with the application based materials testing to

    produce real world solutions that have a sound theoretical

    basis for their development and implementation.

    Such innovative thinking has resulted in several other

    partnerships to provide workable, scientifically proven

    solutions to medical issues. One of the closest

    relationships over the years has been with Professor

    Julian Minns, inventor of the Minns knee replacement,

    former employee of the Newcastle General Hospital

    (Regional Medical Physics Unit). Several such solutions

    are now routinely used in rehabilitation, surgical

    intervention, and injury prevention throughout not only

    the UK but the rest of the world. David Muckle, former

    England football team doctor, has also helped provide

    clinical guidance in projects involving the knee and other

    sports related issues, and several links have been

    forged with manufacturing companies to provide input

    to existing and new products in order that they may

    address the biomechanical issues most effectively.

    One of the key considerations in medical device design

    is the variation of circumstances and individual

    requirements that each particular problem presents

    we are after all, very different to one another, with very

    different issues affecting our personal medical condition.

    Finding the optimal treatment to suit each individual

    patient is crucial to his/her subsequent quality of life but

    there is an urgent need to define more clearly the roleand type of surgical intervention in the management of

    proximal humeral fracture. Recent work is underway

    with Dr Amar Rangan of James Cook Hospital to

    evaluate the current humeral fixation techniques

    available to orthopaedic surgeons for their effectiveness

    at maintaining the integrity of the humerus and enabling

    full functional movement under physiological, cyclical

    loading.

    The team is also very proud of the latest project

    another Knowledge Transfer Partnership, this time with

    Stockton Casting Company Ltd which has helped the

    flourishing SME enormously. Funding has been secured

    from One NorthEast to research new designs and

    materials for a compactor tooth and

    design function analysis.

    I guess in the end it all comes down to healthy

    bones for as long as possible, thats what this team

    is about.

    CHANGING THELIVES OF THEELDERLY

    Professor Farhad Nabhani has been at the forefront of biomedical research in the NorthEast for over twelve years and has an international reputation for excellence, includingcollaborative work with institutions in Denmark, Canada and Holland.

    His research has focused upon several areas of biomechanical interest with specialemphasis on the role of the patella, the ankle, and the back. Professor Nabhani wasinstrumental in attracting the 19th International Conference on Flexible Automation and IntelligentManufacturing to the University of Teesside: FAIM 2009 will run 6th 8th July 2009. For more details visitwww.faim2009.org

    PROFILE - PROF. FARHAD NABHANI

    A team at the University of Teesside is improving the lives

    of the elderly with its work into biomechanics. Farhad

    Nabhani, Professor of Biomechanics and Manufacturing inthe School of Science and Technology, explains how.

    13

  • 8/7/2019 NETWorks Spring 2008

    9/25

    probably involves these neurons. The Hybrid Systems group

    builds computational models of these processes and tests them

    in robotic models.

    The MiCRAM project, funded by EPSRC, is another

    collaborative interdisciplinary project performed between the

    University of Newcastle, School of Neurology, Neurobiology and

    Psychiatry and the University of Sunderland, Centre for Hybrid

    Intelligent Systems, School of Computing and Technology. The

    overall aim is to study sound processing in the mammalian brain

    and to build a biomimetic robot to validate and test the

    neuroscience models for focused hearing. We collaboratively

    develop a biologically plausible computational model of auditory

    processing at the level of the inferior colliculus (IC). This

    approach will potentially clarify the roles of the multiple spectral

    and temporal representations that are present at the level of the

    IC and investigate how representations of sounds interact with

    auditory processing at that level to focus attention and select

    sound sources for robot models of focused hearing.

    Intelligent Systems knowledge transfer projects in the North

    East and UK have brought benefit to both large companies and

    SMEs, including intelligent software to predict distortion in the

    manufacturing processes for printed circuit boards (XAct PCB

    Ltd); an intelligent pattern matching algorithm for increased

    security for credit and cash cards now being further developed

    with a major bank (PinOptic Ltd); and an intelligent pattern

    matching algorithm for the selection of personal vehicle

    registration numbers (National Numbers Ltd). The OVER Project

    aided West Midlands Police with a sophisticated forensic

    computing system for crime data analysis. The HAPPI project

    applied Natural Language Engineering (including

    psycholinguistic databases) to simplify language in timely

    material (online news) to make it accessible to individuals with

    alexia as a result of stroke. Furthermore, Hybrid Intelligent

    Systems contribute extensively to knowledge transfer via project

    collaborations with BT, Reuters (natural language

    processing/classification), ActiveMedia and BAEsystems

    (cognitive robotics), Sage (data mining), and Nonlinear Dynamics

    in the North East (statistics knowledge transferred to

    biotechnology).

    In the Centre for Hybrid Intelligent Systems we always aim at

    linking our research to teaching and reachout in order to

    enhance the students experience. Todays knowledge-based

    society provides students with exciting future-oriented job

    opportunities in education, research and industry. Typical are the

    interdisciplinary advantages which can be gained by integrating

    knowledge from Computing, Cognitive Science, Engineering,

    Life Sciences, Business, Human Computer Interaction, and

    Robotics. Therefore for October 2008 we have designed a new

    MSc programme, MSc Integrated Information Engineering. The

    programme is a new synthesis of interdisciplinary areas with a

    clear application focus. The programme emphasises the

    integration of established computing and engineering concepts

    with novel forms of neural learning, artificial intelligence and

    human-computer interaction. Topics include understanding

    users, internet interaction design, e-technologies for

    management, interactive robots, intelligent systems, and

    ambient systems. In additional research, professional and legal

    issues are an integral part of the curriculum. We welcome

    enquiries from interested MSc students.

    For further information contact Professor Dr Stefan Wermter or

    visit www.his.sunderland.ac.uk

    HYBRIDINTELLIGENTSYSTEMS

    15

    Professor Wermter, Chair in Hybrid Intelligent Systems at the

    University of Sunderland, explains the necessity of integrating

    many different fields of science to produce more intelligent

    systems.

    For many future computing applications such as adaptive

    software products for business industry, smart more

    autonomous automotive vehicles, ambient home environments,

    social robots, and interactive data mining for interdisciplinarybusiness applications, we will need Hybrid Integrated Systems

    where systems benefit from the hybrid integration of various

    components: Software Engineering, Wireless Sensors

    Networks, Human Computer Interaction, Engineering, and

    Intelligent Learning Systems for automatic adaptation. In the

    future a greater need is expected for more selfadapting,

    selforganising, selfevaluating organic and hybrid computing

    systems based on novel forms of adaptive computation and

    integration for larger embedded integrated information and

    engineering systems.

    The Centre for Hybrid Intelligent Systems in the School of

    Computing at the University of Sunderland has an international

    reputation for their research and development in these systems.

    The Centres objective is to research the foundations,

    representations and applications of hybrid systems in order to

    support various themes in information systems, engineering and

    interactive systems, in order to solve complex real world

    problems.

    Encompassing the fields of Cognitive Science, Engineering, Life

    Sciences, Business, Human Computer Interaction, and

    Robotics, the foundation and motivation for our research often

    comes from natural systems, e.g. biological systems, neural

    systems or cognitive performance. We want to exploit these

    foundations in order to build more sophisticated adaptive

    interactive systems, learning agents, self organising information

    systems and robotic engineering systems. For building such

    nature-inspired computing systems we embed neural, statistical

    and/or symbolic representations into knowledge-based adaptive

    information agents. Applications include intelligent information

    systems, interactive systems, adaptive engineering, data/text

    mining systems, cognitive and neuroscience-inspired robots,

    speech/language systems, intelligent web agents and hybridtechniques for medical diagnosis.

    We are coordinating and participating in several EPSRC and

    European research projects on neural networks, hybrid

    architectures, condition monitoring, neural robotics, vision and

    natural language engineering. In 2003/2004 Intelligent Systems

    won the British Computer Science Societys Machine

    Intelligence Award for their work on neural networks. The team

    has coordinated the very successful EU MirrorBot project and

    are currently coordinating the EU project NESTCOM.

    In the NESTCOM project, coordinated by the Centre for Hybrid

    Intelligent Systems, in collaboration with MRC Cambridge and

    University Parma, focus on the central question what it means

    to communicate. As our main focus we explore the

    characteristics of human communication and their relationships

    to the role of networks of mirror neurons. These neurons spike

    when a primate performs an action leading to a reward and

    when it observes another primate taking that action. They have

    been found in monkeys in Area F5. Area F5 is important in

    humans, because it is Brocas area, playing a role in speech,

    and suggesting that mirror neurons are central for action

    understanding, imitation and communication development. The

    development of speech in human infants seems to involve an

    understanding of the reward system of the other mind, and

  • 8/7/2019 NETWorks Spring 2008

    10/25

  • 8/7/2019 NETWorks Spring 2008

    11/25

    Figure 1: Green laser launched to a height of 10km from the

    4.2metre diameter William Herschel Telescope on La Palma inthe Canary Islands. The laser forms a guide signal with which to

    control the telescope adaptive optics system which was also

    built by the Durham University.

    Figure 2: High speed low-light level imager. The camera uses a high speed

    CMOS imaging chip and a customised field programmable gate array (FPGA) to

    enable image capture, pre-processing and data reduction all at real-time rates.

    The device is intelligent enough to selectively read out small regions of interest

    around objects of interest (e.g. bacteria) and follow their movements dynamically

    at extremely high speeds. (photo courtesy Durham Smart Imaging)

    Figure 3: Capabilities of the CfAI precision optical engineering laboratory which

    can provide individual design, manufacture, metrology and test/qualification

    of new products or perform a full end-to-end development of new

    technologies and ideas.

    19

    The Centre for Advanced Instrumentation (CfAI) ofDurham University was one of the first tenants atNETPark and now houses around 20 full-time staffwithin the NETPark Research Institute. NETWorksspoke to Professor Ray Sharples about the world-class research group.

    The CfAI has an international reputation for the design

    and construction of instrumentation for astronomy at

    optical/infrared wavelengths and is supplying facility-class

    state-of-the-art instrumentation to many of the worlds

    major observatories, including the twin Gemini telescopes

    in Hawaii and Chile, the European Very Large Telescope

    in Chile and the James Webb Space Telescope due to be

    launched into orbit in 2013, as a replacement for the

    Hubble Space Telescope. The groups activities are built

    around a core programme of instrumentation R&D funded

    by the UK Research Councils, which involves the

    investigation and development of novel instrumentation

    techniques, particularly in the areas of Adaptive Optics

    and Spectroscopy.

    Many of these techniques also have spin-offs into other

    scientific and industrial applications such as low light

    level imaging and high resolution imaging. The

    technique of adaptive optics was developed to correct

    for the blurring effects of the Earths atmosphere on

    telescopes observing the heavens from a ground-based

    site. Using this technique, in combination with artificial

    laser guide stars [Fig. 1] to control the deformable

    adaptive mirrors in the system, has enabled

    astronomers to obtain pictures from the ground with

    even better sharpness and acuity than is available from

    much more expensive space-based satellites. This

    technique can also be applied to studies within the

    human eye where fixed aberrations of the cornea, and

    dynamic effects due to muscle contraction or the fluid

    within the eyeball, have thus far limited the detail with

    which ophthalmologists can study the light sensitive

    retina at the back of the eye. Scientists at CfAI are

    transferring their knowledge of adaptive optics into

    medical physics to allow the design of a new generation

    of ophthalmic instruments which will enable early

    diagnosis and treatment of both retinal and other

    diseases, such as diabetes.

    In addition to adaptive optics, CfAI has recently begun a

    range of vision science projects including assessing

    potential optical aids for age-related macular

    degeneration, which affects a large fraction of elderly

    patients, and disability glare due to light scattering within

    the eye. One of the key technologies which has emerged

    from the groups research programme is the development

    of a range of intelligent extremely fast (up to 1000 frames

    per second) smart cameras [Fig. 2] which can be used

    to improve the sensitivity of a variety of diagnostic tools in

    medicine and biology. Members of the group have

    recently formed a spinout company, Durham Smart

    Imaging, to exploit the commercial potential of this

    technology. These applications will soon be strengthened

    by the establishment of a Biophysical Sciences Institute

    at Durham University, which will bring together

    researchers from many scientific disciplines to focus onproblems at the frontiers of biophysics and biotechnology.

    Manufacturing is another key area where advances

    must be made if new technologies are to be transferred

    into the mass market. The CfAI has a unique range of

    ultra-high precision machining and metrology equipment

    at NETPark [Fig. 3] which it uses to manufacture

    advanced optical systems for ground and space-based

    instruments. The ability to create arbitrarily complex

    compound lens elements in metal moulds has opened

    up the possibility of replicating much more sophisticated

    image correction lenses which can better correct a

    wider range of vision defects in the eye. These tools will

    enable new concepts in image correction to be brought

    to the marketplace and truly bring a clearer cosmic

    vision to all of us.

    SPACETECHNOLOGYPROVIDESCOSMIC

    VISION

  • 8/7/2019 NETWorks Spring 2008

    12/25

    In every US Air Force Base, there is an instrumentation

    product that comes from County Durham. Andrew

    Wood talks to Rod Taylor, managing director of

    Seaward about how his company has achieved this.

    Rod Taylor, managing director of County Durham-based

    Seaward Group, has grown his company from humble

    beginnings in the early 1980s into a leading supplier of

    electrical testing equipment, employing more than 150.But Rod has not only achieved professional successhis

    personal efforts in supporting local business, particularly

    his role in encouraging firms to work more closely with

    young people, was recognized with an MBE in the 2008

    New Year Honours List.

    The company was originally formed by Jimmy Seaward,

    a retired ICI engineer, who was making voltage testers in

    his garage in Stockton. Rod, who was then working as

    an electronic engineer, bought the business from

    Seaward in 1982 for just 5,000 and moved it to equally

    humble surroundingshis own coal shed. Sales

    expanded rapidly, and the company eventually moved to

    its current location at the South West Industrial Estate in

    Peterlee.

    The secret of Seawards success has been to focus on

    higher-value, niche markets, and avoiding those where it

    can only compete on price. We do not operate in a

    particularly high-growth market, Rod says. In fact many

    parts of the market are relatively mature. So we focus on

    markets where we can demonstrate differentiation, such

    as testing for medical equipment, and where customers

    value innovation that gives them efficiency and

    productivity benefits, he says.

    Despite its relatively small size, with sales of about 12million, Seaward has been able to succeed in a market

    that pits it against major international rivals that are many

    times its size. Products from Seaward are used to ensure

    that products ranging from household electrical devices

    to hospital incubators are safe to use. It also provides

    equipment to test the skin of the Airbus A380, and it

    supplies every US Air Force base with reference

    temperature measuring equipment.

    Rod is a big fan of the North East, and particularly

    County Durham, as a place to do business. Theres a

    good supportive network here, and local agencies such

    as CDDC and One NorthEast are really on the ball when

    it comes to helping business, he says. Seaward was

    recently awarded 200,000 grant from One NorthEast as

    part of a program to develop the next generation of

    medical testing equipment.

    ACHIEVING SUCCESSIN TESTING(WITH HONOURS)

    Whats really interesting about Seaward is that it has

    resisted the trend by companies to shift manufacturing

    to areas of lower-cost labour, such as China. About

    90% of what we supply is made in Peterlee, Rod says.

    Our business is a mix of lots of products, each

    produced in a low-to-medium volume. The labour

    content is only about 10%-15% of the finished product.

    It is much more important to have the flexibility than to

    focus only on labour costs, he says.

    And the workforce of the future is where Rods attention

    is now focused. He took on this issue through the

    development of Aspire, a campaign launched in 2004

    that encourages employers to work closely with young

    people to help raise educational attainment targets in the

    region. Through Aspire, students are offered real work

    experience. It helps make them more upbeat about

    their prospects, he says. His work with Aspire was key

    in receiving the MBE.

    Rod is himself upbeat on Seawards prospects, and aims

    to double its sales in the next 3-4 years through a

    combination of developing new business areas and

    making acquisitions. The company is especially keen to

    supply the market for green energy, such as testing

    equipment for wind turbines. It has set its own green

    targets for reducing carbon dioxide emissions and

    making sure its products are carbon neutral.

    There are some great opportunities out there, and we

    feel we are in front in the key areas, Rod says. The

    Seaward Group comprises four companies. In addition

    to Seaward, Cropico and Clare Industrial produce testing

    instruments for the manufacturing industry and Rigel

    Medical supplies the biomedical testing market.Dedicated to reducing test time, Rigel Medical is a

    market leader in providing electrical safety solutions and

    has built on one of the longest established brand names

    in the industry. Back in the 1970s, Rigel launched the

    worlds first IEC 601 electrical safety analyser and Rigel

    Medical continues the commitment to providing

    Innovative and Portable Biomedical Test Equipment.

    Within the next two years, the IEC 62353, a dedicated

    International Standard for Routine Electrical Safety

    Testing, is expected to provide guide lines in making

    dedicated Safety Testing routines for BioMedical Test

    Equipment designed to IEC 60601, and to meet the new

    test requirements, Rigel Medical has launched the Rigel

    288 Portable Electrical Medical Safety Analyser.

    For further information visit www.seaward.co.uk

  • 8/7/2019 NETWorks Spring 2008

    13/25

    23

  • 8/7/2019 NETWorks Spring 2008

    14/25

    From green fields to dynamic

    science park in next to no time

    The first building, the NETPark Research

    Institute was opened in 2004. 2200 sq m

    specifically designed for R&D and low

    volume complex equipment prototyping

    and manufacture. Leased to Durham

    University for two world-class research

    groups: the Centre for Advanced

    Instrumentation and the Semiconductor

    Crystal Growth and Ceramics Group.

    The Innovation Village will also be completed

    this year. 5 bespoke R&D pods for growing

    and/or investing companies, developed by

    Helios City. The total size will be 2500 sq m -

    units in multiples of 250 sq m

    Swiftly followed by Phase 2 of

    the NETPark Incubator. Total

    projected size 2252 sq m, funded

    by Durham County Council, One

    NorthEast and ERDF.

    Phase 1 of the NETPark

    Incubator followed a year later.

    1600 sq m of office, work and

    laboratory space and meeting

    rooms. Already 100% committed

    with 11 companies including 2

    regional centres of excellence.

    This year NETPark will be the fastest-growing science park in the UK.

    Construction of the Plastic Electronic Technology Centre (PETeC) will be complete this year.

    A 3,000 sq m national flagship facility for the development and exploitation of direct write

    technologies and flexible functional materials (FFM); revolutionary technology that

    independent forecasts predict will be a 16 billion industry by 2015. Managed by Cenamps

    and CPI, the centre is 1 of only 4 currently being built in the world.

    NETPark is North East Englands science, engineeringand technology park for the commercialisation ofcutting edge R&D. Companies thrive at NETParkbecause of:I State of the art facilities and room to grow on a

    prestige siteI Low operating costs

    I Excellent transport links

    I A skilled workforce

    Companies at NETPark have access to cutting edgeresearch from 5 universities within 30 minutes drive andtailored business support that enables them to achievetheir potential. They are part of a like-mindedcommunity that enables each company to flourish,grow and compete with the best in the world.

    NETParks focus is on the physical sciences,particularly plastic electronics, microelectronics,photonics, nanotechnology, and their application in thefields of energy, defence, and medical-related

    technologies.

    13 hectares (Phase 1) are already fully serviced andanother 3 hectare area is in the process of being madeavailable.

    NETPark is developed by a partnership led by DurhamCounty Council including Sedgefield Borough Council,One NorthEast and all 5 regional universities.Management and promotion of NETPark is in the handsof County Durham Development Company, DurhamCounty Councils inward investment arm. Helios Cityis the preferred developer for Phase 1.

    For more information, visit www.uknetpark.netoremail [email protected]

    ABOUT NETPARK...

    25

  • 8/7/2019 NETWorks Spring 2008

    15/25

    INTELLECTUALPROPERTY FORSMALL BUSINESSES

    Your idea is your property!Get patent protection for your business.

    The need to obtain protection for product designs and

    intellectual property is greater now than it has ever been.

    A growing awareness of the benefits of patent protection

    and information can mean thousands saved in product

    marketing and research costs. Patent information is of

    value to major companies, researchers, individual

    inventors, R & D departments, students, SMEsyou.

    Patent documents hold a wealth of technical and

    commercial information. 80% of the information they

    provide does not appear in any other published form.

    They can keep you up to date with the latestdevelopments in technology, product production and

    competitors activities.

    If you have a new invention it could be to your advantage

    to apply for a patent. This will allow you to manage how

    it is used and who uses it. The type of protection you

    need will depend on what you are protecting and how

    you will use it. Often more than one type of Intellectual

    Property may apply to the same creation. Properly

    protected and exploited it gives businesses a competitive

    edge in the market and adds real capital value to the

    business.

    The Patent Advice Centre is a unique service temporarily

    relocated at the University of Northumbria on the first

    floor of the library. As part of the Patent Library Network

    it is ideally placed to help anyone within the North East

    decide which Intellectual property protection they might

    need for their idea Patent, Design registration,

    Copyright or Trade Mark and to check that nobody else

    has thought of it before them.

    Our services include:

    I Information and Advice on all aspects of Intellectual

    PropertyI Document Supply

    I Commercial Patent & Trade Mark searching

    I Current Awareness a patent monitoring service

    enabling clients to follow patent applications in the

    required field as they are published

    I Assistance in searching we will show you how to

    carry out a patent search

    I Intellectual Property Office literature and application

    forms

    If you have a query please call us on 0191 260 3250

    or e-mail [email protected]

    www.newcastle.gov.uk/pac

    COMMERCIAL SERVICES:I Patent search

    I Trade mark search

    I Current awareness a patent

    monitoring service enabling clients

    to follow patent applications in the

    required field as they are published

    I Document Supply

    FREE SERVICES:I Access to patent databases

    I Assistance in searching

    I Basic advice

    I Application forms

    I Intellectual Property Office Literature

    PATENTSadvice centre

    PATENTSadvice centre

  • 8/7/2019 NETWorks Spring 2008

    16/25

    ENVELOPEROOFSSingle ply light grey membraneWALLSWhite acrylic render on blockwork, Blue Staffordshire brickworkplinth.

    CURTAIN WALLINGDouble glazed dark grey curtain walling systemSOLAR SHADING (2 storey units)Dark grey powder coated aluminium solar shading

    M&E SPECIFICATIONMECHANICAL SERVICESAssisted natural ventilation to office area, mechanical extract toWC areas, LPHW Heating, hot and cold water

    ELECTRICAL SERVICESMains, fire alarms, small power, intruder alarm, disabled refuge,general lighting, emergency lighting and data containment

    INTERNALSTRUCTURALSteel frame, load bearing ground floor slab, raised access first floorPre-cast concrete stairs and metal balustradesPARTITIONSMetal stud walls to core areas with insulation

    INTERNAL DOORSTimber veneered flush doors with softwood frames and stainlesssteel ironmongeryLIFTSKone Lexia 420, stainless steel/ powder coated metal wall finishes

    FLOOR FINISHESGeneral Areas Grey carpet tilesWC Areas Ceramic floor tilesWALL FINISHESGeneral Areas white paint finish

    WC Areas white ceramic tilesCEILING FINISHESGeneral Areas - Armstrong suspended ceilingWC Areas moisture resistant tilesWC FIXTURESIntegrated plumbing system, white vitreous Armitage Shanks ware

    INNOVATION VILLAGE POD SPECIFICATIONWHEN ONESIZE DOESNOT FIT ALL

    Helios City is the preferred developer for phase 1 ofNETPark. Mike Parker spoke to Trevor Cartner, directorof Helios City about his innovative developments.

    The team at Helios City knows that a one size fits all

    approach does not work, especially when building premises

    for the most cutting edge science and technology firms.More than any other companies, these firms have very

    specialised requirements and their premises must be made

    to match. Helios City has designed the NETPods at the

    Innovation Village, part of NETPark, to be as individual as

    the companies that occupy them. Each pod is a bespoke

    unit fitted out to the companys requirements. As Trevor

    Cartner, director of Helios City explains, Every science or

    high-tech firm is completely different so we have to work

    extremely closely with each company to ensure their pod

    is built to their exact specifications. It is this individually

    tailored approach that sets the Innovation Village apart from

    other science parks and makes the pods equally suitable

    for young companies outgrowing their original premises as

    well as for multinationals looking to invest in a site at the

    most exciting science park in the country.

    The NETPods are built to the specifications of the

    company but they must also meet a range of

    environmental requirements and standards set by

    NETPark. Thus the Village is carefully landscaped, and

    the building materials used are intended to have

    minimum impact on the environment. This demanding setof design criteria proved challenging but Helios is well

    equipped to meet these demands. Having been selected

    ahead of 60 other companies to take on the original

    development of the site at NETPark, the team is well

    versed in the aims and the overall ethos of NETPark. As

    Trevor Cartner explains, NETPark is going from strength

    to strength and now that the Innovation Village is on the

    way we feel extremely confident that the NETPods will be

    well received by prospective tenants. The NETPods have

    been designed to accommodate the individual

    businesses and with their vast range of facilities, and the

    wealth of networking opportunities available, I know that

    companies will flourish here.

    For further information visit www.uknetpark.net or

    email [email protected]

    29

    Photo by NAPPER

  • 8/7/2019 NETWorks Spring 2008

    17/25

    AWARDSRECOGNISEHEALTHCARETALENT IN NORTHEAST ENGLAND

    31

    The winners of the first ever Business for Life awards,recognising the most revolutionary healthcare companiesin North East England, were announced at a high-profileceremony in Newcastle upon Tyne. Celebrating thesuccess and strengths of the North Easts healthcare andlife sciences industries, the Business for Life Awards arefast becoming a key factor in cultivating future businessachievement in these sectors throughout the region.

    Mike Asher, CEO, Cels said Cels strives to support and

    grow the regions healthcare companies. These awards

    have been introduced not only to recognise and reward the

    North Easts top companies in the industry, but also to act

    as a benchmark for the regions rapidly developing

    healthcare sector.

    The award categories included:

    I Export Achievement, for maximising opportunities to

    exploit and develop new markets or other areas of

    international trade

    I Innovation, for the development of an innovative

    technology, design or process

    I Outstanding Growth, awarded for consistent, sustainable

    and profitable growth

    I Partnership with the NHS, for the development of

    collaboration with the UK National Health Service

    I Business Start-up award, for promising newly established

    companies in the healthcare sector

    I The Honorary Chief Executives Award was presented

    for outstanding achievement and contribution to the sector.

    And the winners wereExport Achievement

    - Hart Biologicals

    Hart is a manufacturer and supplier of specialised biological

    reagents for the monitoring of blood coagulation disorders,

    oral anticoagulants and anti-platelet drugs in surgery,

    laboratory and clinic environments. Hart have increased

    their export sales by 47% in the past year and have

    identified 4 new markets for their products, marking them

    out as the clear winners of this category.

    Innovation

    - UK Haptics

    UK Haptics develop virtual reality training solutions for

    practice based learning and skills rehearsal in medical and

    clinical situations using 3D virtual environments to create life

    like simulations. After receiving the award, Gary Todd, MD

    of UK Haptics commented We are delighted to have won

    the award for innovation, it is a great achievement for UK

    Haptics in the face of stiff competition and the awards really

    put the North East in the spotlight with regard to its

    excellent healthcare sector.

    Outstanding Growth

    - ImmunoDiagnostic Systems (IDS)

    IDS is a specialist manufacturer of manual healthcare

    diagnostic kits focusing on bone metabolism. IDSs flagship

    products identify the presence of Vitamin D in human

    serum. As vitamin D relates to the regulation of calcium it is

    being increasingly linked to the prevention of various

    cancers as well as being a factor in diabetes and heart

    disease. By creating closer relationships with distribution

    partners IDS have seen turnover increase by a massive

    22% in the past year, and 49% the year before which

    marked them out as the leader in this category.

    Partnership with the NHS

    - Peacocks Medical Group

    Peacocks Medical Group measures, manufactures, and

    supplies complex bespoke orthotic devices to patients and

    hospital trusts throughout the UK. One area of particular

    concern is the provision of pressure relieving diabetic

    footwear and insoles to patients who are at risk of

    ulceration. Peacocks have been working on a pathfinder

    project with the Diabetic Clinic at Newcastle Hospitals NHS

    Trust. Chris Peacock, Group MD commented: Peacocks

    were delighted to win the award for partnership with the

    NHS at Cels award ceremony. Peacocks was founded in

    1903 and has been working with the NHS since its

    inception in 1948. We are thrilled to have our hard work

    recognised. In this modern globalised world you have to

    always be one step ahead of your competitors. We hope

    that this award will highlight to people that we have a world

    class service right here on the doorstep.

    Business Start Up

    - Applied Neurodiagnostics

    Applied Neurodiagnostics is a young dynamic company

    whose main aim is to develop and manufacture medical

    devices using as a base revolutionary eye tracking and pupil

    measuring devices. They are developing the Pupilmetrix

    PLR60, a visual field test device used to determine the

    presence or absence of damage to the retinal nerve fibre

    layer as part of a patients routine eye test. Keith Morris,

    General Manager said: Winning the award was a surprise

    given the other finalists and is a tremendous boost for us as

    a very young company. It is recognition of the teamwork

    between all our employees and our partners in developing

    our PLR60 product.

    Chief Executives Award

    - Harlow HealthcareA major manufacturer and supplier of specialist products to

    both the public and private sectors including manufacturing

    and exclusively supplying the new Personal Child Health

    Record, a product used by every mother and new born

    child in the UK. The company also designs, manufactures

    and distributes the UK national standard growth charts for

    height, weight, head circumference and bmi. With an

    expanding business they are about to bring on line 35,000

    sq ft of new build warehousing, production and offices in

    South Tyneside, a reflection of their commitment to the

    provision of a print management service to the health

    sector. John Short of Harlow stated: We are pleased and

    delighted to receive this great accolade which is a true

    reflection of the hard work put in by all the people who have

    worked for us and with us over the past 60 years.

    The winners of the awards were entered into the National

    Medilink Awards. Mike Asher said: All of us at Cels are

    delighted to celebrate the successes and achievements of

    our companies in the north east healthcare and life

    sciences sector at the awards ceremony.

    He continued The event surpassed all expectations, and

    our congratulations go to the winners and finalists in what

    was a very closely fought competition. We look forward to

    supporting the companies and wish them every success at

    the national finals.

    The awards were organised by the Healthcare Network, a

    support service for the regions healthcare companies run

    by Cels, the organisation driving the growth of the

    healthcare economy in North East England. They reflect

    the regions growing healthcare and life science economy.

    Thriving in recent years, this sector currently includes world

    leaders in biologics manufacturing and successful

    companies in the fields of medical devices, assistive

    technology and health informatics.

    The competition attracted key support from UK Trade &

    Investment, sponsors of The Export Achievement Award,NHS Innovations North, sponsors of the Innovation Award,

    Sintons Solicitors, sponsors of the Outstanding Growth

    Award, the North East Strategic Health Authority, sponsors

    of the Partnership with the NHS Award and Marketwise

    Strategies who were sponsors of the Start-up Award.

    To find out more about health, healthcare and life sciences

    and the support available in North East England visit

    www.celsatlife.com.

  • 8/7/2019 NETWorks Spring 2008

    18/25

    LEADING THEWAY IN MEDICALDIAGNOSTICS

    Located in Hartlepool, Hart Biologicals Ltd was foundedin August 2002. Although still a young company, themanagement has extensive experience in the fields ofclinical sciences and diagnostic reagent manufacture.

    That wealth of experience has produced early success

    and in the first ever Business for Life awards organised

    by Cels last November, Hart carried off the Export

    Achievement award.

    The awards celebrated the successes and achievements

    of companies in the North East healthcare and life

    sciences sector, and the Export award, sponsored by UK

    Trade & Investment, recognised Harts work in developing

    new markets. The company manufactures a range of

    clinical laboratory diagnostic products suitable for the

    worldwide healthcare market.

    Indeed as Managing Director Albert Pattison, whose

    background is in biochemistry and haematology, explains:

    Exporting has always been part of the company's

    business plan and lies at the heart of our long term future.

    In Europe the countries we export to include Germany,

    France, Italy, Austria and, further afield, we also export to

    India, Hong Kong and Australia.

    The company is rapidly expanding its global presence

    through a policy of enlarging and strengthening its

    international distribution network, and developing

    strategic alliances and partnerships with people and

    organisations where there are common business

    interests.

    Providers of key pathology laboratory services to NHS,

    Independent and Private Hospitals and Primary Care

    Trusts, the company operates at the leading edge of

    medical diagnostics and is an integral part of the North

    Easts successful and thriving healthcare sector.

    The sector contributes 8 billion to the regions economy

    and is responsible for employing 172,000 people. .

    As Mr Pattison outlines the companys operations: We

    specialise in the manufacture of clinical diagnostic

    reagents for use by hospitals, GPs and pharmacies which

    are used to help test and monitor people who suffer from

    blood coagulation disorders or are due to undergo major

    operations such as heart bypass surgery.

    We also supply equipment and reagents for testing

    patients who are taking the anticoagulant drug warfarin

    after having suffered from thrombosis, heart valvereplacement or other cardiovascular problems.

    Our company strategy is to develop diagnostic assays

    within particular, well-defined sectors where the

    experience of our management team can be maximised

    to bring added value to orders and contracts by offering

    more than simply a manufacture and supply facility.

    The Hart Biologicals range of products focuses on key

    areas of the haemostasis field:

    I Anticoagulant drug therapy monitoring through the

    Manchester Capillary PT Reagent kit and associated

    products.

    I Platelet function testing through the platelet

    aggregation and Ristocetin Co-Factor range of

    reagents.

    I Assessment of congenital or acquired clotting factor

    disorders through the provision of high quality factor

    deficient plasmas.

    I Quality Control and Reference plasmas for routine and

    specialised assay types.

    For further information concerning Hart Biologicals Ltd, its

    products and services, please contact:

    Hart Biologicals Ltd.

    Units 13-15, Newburn Bridge Industrial Estate,

    Mainsforth Terrace, Hartlepool TS25 1TZ

    T 01429 271100 F 01429 277085

    www.hartbio.com

    BIOMEDICAL ANDBIOMOLECULARSCIENCES ATNEWCASTLEUNIVERSITY

    Newcastle Medical School is one of the mostprestigious in the country. At Newcastle we offer arange of undergraduate programmes leading to a BSchonours degree.

    Courses include:

    I Biochemistry, Biochemistry with Immunology

    I Biotechnology (with or without industrial placement year)

    I Biomedical Sciences (4 year MSci also available)

    I Genetics, Human Genetics

    I Medical Microbiology and Immunology

    I Pharmacology

    I Physiology

    The courses reflect our research strengths in the

    biosciences and are informed by the latest

    developments. Our focus on excellence and skills

    development ensures our graduates are well-equipped

    for employment in a range of careers.

    Why Newcastle for the Biomedical and Biomolecular

    Sciences?

    I Outstanding score in the national Quality Assurance

    Agency subject reviews in the Biological and Medical

    Sciences, reflecting excellent teaching and student

    support and first class facilities

    I Top scores (5/5*) in the latest national Research

    Assessment Exercise for Medical and Biological

    Sciences

    I Research-led teaching and a final year project in a

    University Research Institute ensures exposure to

    state of the art knowledge and technologies

    I Postgraduate opportunities available for PhD or

    Masters study in Biomedical and Biomolecular

    Sciences

    I Flexible programme; sharing of first year modules with

    a range of bioscience degrees allows students to

    transfer between courses at the end of the first year

    I Students may apply for transfer to Medicine or

    Dentistry (limited number of places available on acompetitive basis)

    I Strong links between basic science and medicine

    ensuring relevance of degree programmes

    I One of the UKs top Universities for technology

    transfer (see www.ncl.ac.uk/business/success)

    I Newcastle has been designated one of six Science

    Cities

    The City

    Newcastle is a great city and has been described as

    one of the most exciting, friendly and cosmopolitan

    cities in the UK. It is set against the backdrop of the

    beautiful Northumbrian countryside, in easy reach of

    beaches, hills and moorland. Newcastle has excellent

    links with the rest of the UK and Europe and a relatively

    low cost of living.

    Our students

    We welcome applications from well-qualified and

    enthusiastic students from the UK and overseas. Our

    normal A level offer is ABB (AAB for the MSci) and we

    are happy to consider applicants with other

    qualifications. Bursaries are available for international

    students.

    www.ncl.ac.uk/biomed/undergrad

    For more information please contact Dr Christopher

    Baldwin, [email protected], telephone

    33

  • 8/7/2019 NETWorks Spring 2008

    19/25

    NHS INNOVATIONSNORTH ASSISTCANCER TESTBREAKTHROUGH

    High definition ultrasound technology for early detectionof cancers is close to becoming a reality thanks toexperts at Newcastle General Hospital and technologytransfer organisation NHS Innovations North.

    The new techniques will allow doctors to be able to

    probe deeper into the body and produce clearer images

    of potentially diseased organs.

    Retired consultant clinical scientist, Tony Whittingham

    developed the imaging technique with the assistance of

    technologists George Mitchell and Michael Feeney at the

    Regional Medical Physics Department based at the

    hospital. The team, however, is remaining tight-lipped

    about how the scans work until the final patent

    application is filed.

    The technique won recognition at NHS Innovations

    Norths Bright Ideas in Health Awards, the annual

    innovation competition for the regions 70,000 NHS staff.

    Now the method, along with equipment adapted to carry

    out the procedure, is due to be patented in the coming

    months. This will safeguard the intellectual property on

    behalf of the Newcastle upon Tyne Hospitals NHS

    Foundation Trust as well as encouraging suitable

    organisations to become involved in commercialising the

    technology for worldwide use.

    Traditional diagnostic ultrasound has been around since

    the 1960s and is used worldwide as a matter of routine

    to help clinicians assess the health of internal organs. It

    involves running a probe adapted to transmit ultrasound

    waves over the skin, in order to create images of bodily

    tissue that are interpreted by those skilled in the field. It

    is used in a variety of fields of medicine, including theimaging of unborn babies and the diagnosis of tumours.

    Tony explained: "With ultrasound at the moment, the

    deeper you go into the organ the poorer the images. Our

    new techniques will make it possible to see areas of the

    body we have previously never been able to scan

    successfully in terms of obtaining a clear enough image.

    Having worked in medical ultrasound for 35 years, I

    have come to know the limitations of current techniques

    and I am optimistic that what has been developed will

    make a real difference.

    We hope this is going to make a significant contribution

    to patient health worldwide, by making the detection of

    deeper tumours easier, in liver or eye cancer for

    example.

    With the expert help and financial support of the team

    at NHS Innovations North, a patent filing is imminent.

    Their involvement has been crucial in taking our ideas

    this far, and we are delighted that NHS Innovations North

    is now seeking commercial partners to take the idea

    forward.

    NHS Innovations North is the intellectual property

    management service available to all NHS Trusts in the

    North East of England, and helps NHS employees bring

    their ideas to life. By protecting the intellectual property

    associated with an idea - for example by patenting - and

    then licensing the idea for manufacture to an industrial

    partner, NHS Innovations North seeks to further develop

    the knowledge economy of the North East. Their remit is

    to improve healthcare and generate revenue for both the

    NHS and the licensee.

    As one of a network of nine regional innovations hubs

    across England, funded by the Department of Health,

    the Department of Innovation, Universities and Skills and

    One NorthEast, NHS Innovations North was set up in

    2001. The service is delivered on behalf of the NHS by

    RTC North, one of the most successful technology

    transfer companies in Europe with many years

    experience of this field.

    Since its inception NHS Innovations North has built up

    an enviable reputation as one of the leading innovation

    hubs in the country, with many technologies being

    transferred from the regional NHS into the commercial

    arena.

    Director of NHS Innovation North, Dr Richard Hoare, said

    of the unique opportunities available to industrialpartners:

    We welcome contact from any regional company that

    seeks new product ideas in the medical related field or

    would like help accessing the healthcare market. Our

    service and team will actively support these companies

    in taking on new technology, providing the likes of

    market research and the negotiation of licensing

    agreements

    This years Bright Ideas in Health Awards will take place

    at the Hilton Newcastle Gateshead on the 8th May 2008.

    The 10,000 prize fund will be used to recognise a

    winner and two runners-up in each of the two categories

    - innovative technologies & devices and innovative

    service delivery.

    Backed by the regions NHS Trusts, this years Bright

    Ideas in Health Awards are sponsored by the Cels

    Healthcare Network North East, Urquhart-Dykes & Lord

    LLP Patent Attorneys, Watson Burton LLP Law Firm, One

    NorthEast, Hargreaves Elsworth Patent Attorneys and The

    Centre for Design Research at Northumbria University.

    For more information on how NHS Innovations North can

    assist your organisation, please contact the team on

    0191 516 4400, email:

    [email protected] or visit:

    www.nhsinnovationsnorth.org.uk

    Dr Tony Whittingham, front, and senior technologists

    Mike Feeney, right, and George Mitchell

    Picture: Leanne Holcroft Traditional ultrasound machine in use

    35

  • 8/7/2019 NETWorks Spring 2008

    20/25

    THIGH BONECONNECTED TOTHE HIP BONE...

    Professor Unsworth has been studying human joints for

    most of his academic life. His specialism is biotribology,or understanding the lubrication, friction and wear in

    human joints. He is still enthused by the possibilities of

    new types of artificial joints and is particularly keen onlearning from biology in order to make artificial joints

    last longer.

    When I first started researching in this field, Professor

    Unsworth said, surgeons were reluctant to put artificialjoints in to people under 55 years old because of how long

    these joints would last. Nowadays much younger sufferers

    demand these joints and over the last 50 years, when life

    expectancy has increased by a further 10 years, the

    demands put on these joints are much greater.

    Artificial joints have come a long way since ivory was used

    back in 1891 to replace the worn out femoral head. Total

    joint replacements are now common and joint resurfacing is

    becoming popular because of the minimal bone removal

    and excellent early results. In the early 1960s ultra high