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NEUROLYTIC BLOCKS
Involves blocking of sympathetic chain at various levels
Prevents transmission of pain impulses from the target organs to the brain
COMMON NEUROLYTIC BLOCKS
Stellate ganglion block
Thoracic sympathetic chain block
Coeliac plexus block
Lumbar sympathetic block
Superior hypogastric block
Ganglion impar block
STELLATE GANGLION BLOCK
Stellate ganglion formed by union of
Middle cervical
Lower cervical
First thoracic segment
THORACIC SYMPATHETIC CHAIN BLOCK
Not used widely
High risk of pneumothorax
Middle and lower thoracic region
LUMBAR SYMPATHETICBLOCK
Needle introduced at the level of L2 or L2 + L4
Pain relief to pelvis and lower limb
Volume required – 8 to 10ml
SUPERIOR HYPOGASTRIC PLEXUS BLOCK
From splenic flexure of colon to middle 3rd of rectum
Pain relief to pelvis and lower limb
Most difficult block to perform
Needle has to enter through a small triangular space between iliac crest and transverse process of L5
Volume required - 7ml for each side
SUPERIOR HYPOGASTRIC PLEXUS BLOCK
GANGLION IMPAR BLOCK
Walther’s ganglion - lies in front of S2, S3
Pain relief for lower rectum, anal canal and perineum including vulva and vagina
Patient in lithotomy or lateral position
Bent 10cm needle introduced in front of the coccyx
Finger inserted into rectum to guide the needle close to the sacral curvature
Volume required - 10ml
GANGLION IMPAR BLOCK
HISTORY1914 – KAPPIS – first block in lateral
position
1920 – WELDING – anterior approach.
1927 – LABAT – now followed retrocrural approach in prone position.
1982 – SINGLERS – CT guided transcrural approach
1983– ISCHIA – posterior transaortic approach
AREA OF SUPPLY
LOWER END OF ESOPHAGUS UPTO SPLENIC FLEXURE.
LIVER,SPLEEN
RETROPERITONEAL STRUCTURES LIKE PANCREAS, KIDNEY.
INDICATIONSChronic malignant & non malignant visceral pain
1. Upper g.i. malignancy2. Chronic pancreatitis3. Acute pancreatitis4. Repeated abdominal surgeries5. HIV related sclerosing cholangitis6. Diagnostic purposes7. Abdominal angina
ROLE IN ACUTEPANCREATITIS
Steroids improved morbidity and mortality
Continuous infusion for pain relief
CONTRAINDICATIONS
ABSOLUTE
Anti coagulant therapy Coagulopathy
Anti-blastic cancer therapy
Bowel obstruction
Patient on disulfuram therapy
RETROCRURAL APPROACH
Bilateral Posterior approach
Splanchnic block
Drug deposited behind the crus of diaphragm
Unilateral approach
Right sided only
Needle placed anterior to crus of diaphragm.
ANTECRURAL APPROACH
COMPLICATIONSCHEMICAL
ALCOHOL FACIAL FLUSHING, PALPITATIONS, DIAPHORESIS
PHENOL TRANSIENT TINNITUS, FLUSHING,MALAISE CNS STIMULATION, MYOCLONUS, SEIZURES,HYPERTENSION,ARRYTHMIAS,HEPATIC
&RENAL INSUFFICIENCY
EFFICACY OF COELIACPLEXUS BLOCK
Controversy Regarding Efficacy relative to opioid therapy
Efficacy relative to various approaches
Comittment to neurolysis despite remote risk of paraplegia
ADVANTAGE OF COELIAC PLEXUS NEUROLYSIS
Better long term pain relief
Decrease drug dose for maintainance
Better quality of life
Improved performance status
Overcomes the G.I.T effects of opioids
In weight and survival rate
ALCOHOLCOMMONLY USED
HYPOBARIC
CEPHALAD SPREAD RADIOGRAPHICALLY
USED IN CONCENTRATION OF 50-100%
VOLUME REQUIRED-40 ml
ALCOHOLADVANTAGES
LONGER DURATION OF ACTION
EASILY AVAILABLE
IMMEDIATE NEUROLYSIS
PAIN ON INJECTION CONFIRMS CORRECT PLACEMENT IN THE BLIND APPROACH
LESS AFFINITY FOR VASCULAR TISSUES
PHENOL HYPERBARIC
CAUDAL SPREAD
RADIOGRAPHICALLY
7.5 – 10% SOLUTION PREFFERED
MAXIMUM DOSE – 40 mg/kg
PHENOL
DISADVANTAGES NO COMMERCIAL PREPARATION
HIGH AFFINITY FOR VASCULAR TISSUES
SHORTER DURATION OF ACTION
THAN ALCOHOL
LOCAL ANAESTHETICS
0.25% BUPIVACAINE PREFFERED FOR
INTERMITTENT ADMINISTRATION
6-8 ml/hr 0F 0.1% BUPIVACAINE
PREFFERED FOR CONTINUOUS
ADMINISTRATION
KEPT FOR MAXIMUM OF 7 DAYS
SUMMARY
Very useful tool in the armamentarium of the Interventional pain specialist
Applied early for better results
Training in the PG period under expert hands is a must