Neuropsych Test 3 Fall 07

7/21/2019 Neuropsych Test 3 Fall 07

1/6

.

/

Name: n G ~

BIOL4220

NeuroDsvcb Fall 07 Exam #3

Dr.

David Tam

1

Warning:

Anyone found cheating will receive a zero grade for the

6. The evidence sbowing

tbat

tbe release of dopamine induced by

entire course.

ampbetamine does not require action

pot

entials in presynaptic

1. Wbicb

drug

can be used as anti-ast

hma

tic

and

decongestion agent? neuron is t

hat

(

a. MAOI (monoamine oxidase inhibitor). .1 . a. it depends on binding of dopamine to the postsynaptic receptors.

b. Haldol. V it depends on the presence of magnesium.

c. SSRI

serotonin reuptake inhibitor). it depends on depolarization Qfthe presynaptic terminal.

E ~ h e ~ m a e p ~ d

of

Ca

++

entry to the neuron or action potentia ls in the pre

y .

Rltalm: syoaptlc neuron.

e. it releases inquantal amount.

2. Wbicb oftbe following isNOT one

of the therape

utic use

of

amm

pbetamine? .

7. Normally, tbe

transport

of dopamine into tbe synaptic vesicle is

~ t r e a t i n g

AHDH.

pro

moted

by

tbe

~ t r e t i n g

narcolepsy.

r)

j )

exchange ofH 'iOns out of th e vesicle along the pH gradient.

.....er.-

treating obesity.

/

y

binding with Ca+ t ions. .

/"d:' t r e ~ t i n g

bronchial disorders such as asthma and decongestion.

y .

entry ofCa++ ions.

(!)

tr

eating

d. activation

of

dopamine transporter.

e. inhibition of dopamine auto receptor.

3.

The molecular action

of amphetamine at

the synapse is

. , I \)\ -- ? )

reversing the dopamine transorter (and/or norepinephrine transporter). ~ 8. At higb dose, ampbetamine

can

act L[Yf l{/

J )

\ i'

bfuding

as

ana go

iiist of

dopamine post-synaptic receptor.

AC an anti-diarrhea agent. ,

!/

0-

c:

I

binding as an antagonist of dopamine post-synaptic receptor.

@

MAOI (monoamine oxidase inhibitor) exerting anti-depressant effects.

d.

blocking the dopamine autorecptor.

'I anti-nausea agent.

e. increasing the vesicular release

of

dopamine.

, anti-phobia agent.

e. anti-Alzheimer's agent.

4. Tbe excbange-diffusion model

of ampbetamine

says tbat the action

of amphetamine at

the synapse

is

produced by

9. Amphetamine can stimulate dopamine syntbesis by tbe mechanism

exchanging amphetamine into the presynaptic neuron and dopamine

of

,

\ .

C J

out by reversirig the tr

aQ.spo

rter' s pumping direction into ins

id

e ou

t.

flushing out the cytoplasmic dopamine, which reduces the end-product

b.

facilitating vesicular release of dopamine. inhibition

effect..

c.

blocking the dopamine receptor at the post-synaptic neuron.

b. breaking down dopamine at the synaptic cleft.

d.

blocking the dopamine autoreceptors.

c. 'binding permanently with amphetamine at the post-synaptic receptor.

e.

blocking the enzymatic breakdown

of

dopamine.

d. increasing the permeability of dopamine across the blood-brain barrier.

e. neurotoxic oxidation by amphetamine.

5. Normally VMAT (vesicular monoamine transporter) is used to

a. pump dopamine tom the synaptic cleft into the pre-synaptic terminal .

10. Ampbetamine can produce the fo llowing behavior/physiological

( ;> pump monoamne (s u

Ch

as dopamine) into the synaptic vesicles.

effects except one. Which is the exception?

:;y,- pump

Na

+jofisourof thecell inexchangeforK ion

a. fu

lingof

exhllaration

d. regulate the synthesis of dopamine.

\- b. increases in confidence

maintain the concentration gradients ofNa+ and K+ ions.

c.

improves in general motor perfonnance but not fine motor skills

d. heightens alertness

D

fatigue

Copyright 2007 by David Tam. All Rights Reserved. Confidenti

al

use by registered studerits only. All other uses or distribution are prohibited.


2/6

2

ame: Student10 :

BIOL4220 Neuropsych

Fall07 Exam#3

Dr.DavidTam

11. Whichof

the

followingisNOToneof thesymptomsof chronicuse

- of

highdoseamphetam ine?

l.. restlessness

hyper-em9tionality

@ p-ataania

.K.' difficultywithwork

or

inter-personalrelationships

20. Which

oftbe

followingis anexecutivefunctiondiso

rder

?

/ ADHD

. f. ODD(oppositiondefiantdisorder)

c. CD(conductdisorder)

d.

HFA(higherfunctionautism)

( )

Parlffilson's '

disorder

Copyright 2007by DavidTam. A

ll

RightsReserved. Confidentialusebyregisteredstudentsonly. Allotherusesor distributionareprohibited.
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3/6

3ame

:

Student

ID: BIO

L422

Neuropsych Fall07

Exam

#3 Dr .David

Tam

21. Whichof the followingisNOTaco-morbiddisorder that co-exists

26.

Whichof the

fo

llowingd rugsisus

ecpn the treatmen

tof ADHD?

- - \

withADHD? \ :1

-:: i:)

amphetamine

or

cocaine-classdrugs.

C 'J. ,l n )

. . , \ \ .1 '

a. anxIetydIsorder _ .

c

'

.. lithium. /

.

, . - r

"

'

.\

" {

b.

Tourette'ssyndrome {Y

- .., '1 . ' "

, -

c: 'SSRI

(selectiveserotoninreuptakeinhibitor).

c.

readingdisability

d. MAOI (monoamineoxidaseinhibitor).

A "

onductdisorder

e. antipsychotics.

s

y c h o s i s

27. The molecularactionof Ritalin(methylphenidate)

for

treating

22. Whichpart of the brain that showsadecreaseinmetaboJiSnUntbe ADHDis '

neur

opat

hologyof ADHDfro m

PET

orfMRI imagingstudies?

a.

blockingthedopaminepost-synapticreceptor.

pre-frontal

co

rtexandbasalganglia.

b.

blockingthedopamineautoreceptor.

(1 cr

eM

e

1(\

oc.. (.,

\'

rcJ !jnr

b .

thalamus.

blockingthe'Ceuptakeof dopaminetransporter .

he,(rJA ((\ S

\Y

Cd\) rn

c. cerebellum.

d. blockingthereuptake

of

norepinephrinetransporter

d. brainstem.

/-( ) ( (I

r()d(y (

fO?. (1

.

IJ}h

e. blockingthereuptakeof glutamatetransporter

e. hippocampus.

28. Themolecularactionof Strattera fortreating

A

DHD is

23. Which

of

the

followingisapsychophysicsassessmenttestfor

a.

blockingthedopaminepost-synapticreceptor.

impulsivitytoresolveaconflictbetween

the

color

and

meaning

of

a

b.

blockingthedopamineautoreceptor.

word?

c.

blockingthereuptake

of

dopaminetransporter.

a.

stoptasktest.

@

blockingthereuptakeofnorepinephrinetran

sp

ort

er

.

- /

b. tower

of

Hanoi

game

test.

e. blockingthereuptake

ofglufamate

transporter.

. c. fluencytasktest.

29.

Basedonthe

treatment

modelof ADDD,theneurochemical

A t\

troop

fes

t:

hypothesisof ADDDis

due

to

reaction-timetest.

a. hyperfunction

of

dopaminergic/noradrenergicsystem.

S:

J0.\

1.

,

24. One of

the

characteristics

of

AD

HD

patientsis

that

theyoften

hyofunctionof dopaminergic/noracirenergicsystem. ';.,

performtbe stoptask. testwith a compar

ed

to nor

mal

c. hyperfunctionof glutamergicsystem. \

'subjects.

d.

hyperfunctionof GABAergicsystem.

a.

shorterreactiontime

e.

hyperfunction

of

serotoninergicsystem.

lungerreaction

time

~

30.Whichof thefollowingisNOT oneoftheeharacteristicsof

thesamereaction

time

schizophrenia?

d.

longerattentionperiod

;4.

delusion

e. shorterattentionperiod

.JY. disturbanceintheform

of

thought

25. The useof Tower of Hanoigameistotest

disturbanceinthecontentof thought

II

}

A

thereactiontimetostopongoingaction.

.y hallucination

' \l!V

associationskills

with

multipleobjects.

(!)

mama

c. t

he

ability

to plan

withintermediatestepsusingworki

ng

memory

. d :

memorytasktorememberphotographical1y.

"e. thespeedof motortask.

Copyright2007by DavidTam. AllRightsReserved. Confidentialusebyregisteredstudentsonly. Allotheruses

or

distributionareprohibited.


4/6

4

ame: Stude

nt

ID:

BIOL 4220

Neuropsych

Fall

07

Exam #3

Dr.

David

T

am

31.

Wb at

is

tbe disorder

that e

xhibits

crossm

odality

association,

such

as seeingsound or hea ring light?

a. delusion.

b. psychosis.

schizophrenia

\...!) synesthesia.

e. hypersensitivity.

32.Druginduced

psychosisby

cocaine

or amphetamine indicatesthat

ra;

b.

c.

d.

e.

paranoia may be

linked to '

hyperfunction ofthed o p a m i ~ e r g i c system .

'StY

z....

hypofunctionof thedopaminergic y s t e m . --;,'

hyperfunction

of

theserotoninergicsystem.

hypofunction

of

theserotoninergicsystem .Pj ('

...1

f ('-..

the a n x i e t ~ c ~ u s ~ d b ~ realfearof .gettingarrestedbecauseof the

societalcnmmahzatlOnof recreatIOnaldrugs.

36. The

neuropathology of

sc

hiz

o

phre

nia incl

ud

esthe following

abnormalities except one. Which is the exception?

.,

a. neuralformation

b. neuralmigration

c.

synaptogenesis

A neuralpruning

smallerheadcircumference

37.

The suppression of the sta rtle reOe/by precedi ng

softer

toneis

a.

.JK

'38

.

called

end-productinhibition.

pre-pulseinhibition.

mania.

fight-or-flightreflex.

ahedonia. C

.

. , '. ' ,

\, .

,

'

1

l

:"

\ .

)

..

\.

). , i , '

, . _

~ . . . . , \

33.

Which ofthe followingisNOT

one

of the symptoms that involves f l: respondwithoutany s ~ l e inthepre-pulseinhibitiontest.

the disturbances

of

emotions inschizophrenia? respondwitha bigstartlein thepre-pulseinhibitiontest.

U .

h I . tt

h'

h .

t'

t ft '

slOgP

ySIO

oglca es , sc

lZOp

renlc pa len s0 en

a. inappropriateemotions. . '

b. noemotion.

c. noexpressionof emotionsuchas monotone.

d. suddenchangeof emotions.

hallucination.

34. The ~ ~ i C s u b t y ~ of schizophrenia ischaracterizedbythe

a.

emotIOn.

Isturbances. \

'

,I

'\

motor-disturbances.

V.

sensorydisturbances.

d. memorydisturbances.

e. cognitivedisturbances.

35.

Positive

symptoms

of

r e n i refe

r

to

the

a.

b.

A

.

freezeposture.

devoid

o f b e h a V i o r ~ J ; ~ t D

devoid

of

thoughts.

~ v ,

devoidof emotions.

excessivebehavior,thoughtor emotIon.

\1

\

I :)

:,,;c.

failtorespondcorre.ctlynamingthecolorintheStrooptest.

respond

slowerin the

stop

t

ask

test.

/ .

failinthefluencytest.

39.

One of

the side effectsof ty pical antipsycboticsis

a. hyperphagia.

b. hyperactivity.

c. insomnia

extrapyr

am

idalsymp toms.

e.

hypertension.

40.

Lactati

on isone oft heside effectsof

(a)

typ icalantipsychotics.

b

atypicalantipsychotics.

... e: antianxietydrug.

%. antidepressants.

antiepileptics.

Copyright

2007byDavidTam. AllRightsReserved. Confidentialusebyregisteredstudentsonly. Allotherusesor distributionareprohibited.


5/6

/ '

/

/

5

" /

-

.S

-

tudenUD:.

B I O L A 2 2 0

n r o p s y ~ 1 l ..

.F.ir01 E

I8;D.1

.#3

Dr.DavidTam .

jbich

of the .following

is

NOT

one

of th

eenvironmental

sU.ess

ors

,ihe cantr iggerschizopbreDia? . ' .

'

'" ,/

emotiomll

negativity. .

b:

'

critical

or emotio'nalityover-involvepfaniily d i m a t e ~

.

c.

.over-stimuIatioriin:

o e i ~ e n v i r o n m e n t .

d. .stressful' e v e n t ~ y o n d p e t s ( ' ) J l a 1 control. .

. positivetiriiily

problem

solviiigskills.

I . '.

4 ~ .

HldcIenPane

in

the Joh

ali wiJl

dow

o r r e a p O n d s t ~

the .

pane

thli

tiS

. . . . .

knownioselfand

others. .

. : kJlown.tOselfbut

DOt

otherS.

,...'.\ knowntoothers but o t , s e 1 f ~

~

. notknoWll'tosetfor others. .

u n k n ~ w n toanybody:.

43.

Which P . o ~ i o

l l t t d lJilid

ow

eorres:poilds

ta

tbearea'

that

u

' kOOWD'tQothmblat

t : S ' e l f ( ~ i c

h s ( ) c ~ e S P O

tl\e .

igDoranJarea)?: " .

.a,

open

paner

Q)

b ~ i n d

pane. .

. c. hldden.pane.

. d.unknown pane.

e. .supematuralpane.

44.

I { p o

e d . g e a l ) ( )

the

conditions

e ~ ~ r i c e d b y s e ~ ~ p J u ; ~ h ~ t

.such

h ~ t i n g v o i c ~ Q n berevealed

to

othetsby

expandillgthe.

Johari

d 9 - w

QpeD:Plineto

JljddenPaire.

T h i a e 1 p a u d ~ l

.

.lo1t.-d w

fs.e.tOlbpl'SllecJ.

by

self-dise)t>sure.

.

: a s k i n g f o r f ~ b a e k . .

med;i

tationr

' '

d.

hypJio$is. . . ' . '.'.'

e. "

psychic

. S P ( e x ~

O n 1 .

45.

Wb

ieh;

,of tbe

o J i ~ J , l g ~ N O T

~

f 1 h e m p t Q l B s

ofille

dyspboric

~ ia e p r :

~ J i ?

. .... . ' ' ., ." .

a. hope1

eunes$ ..' . . .

b beJples.mes

s

c.

worthles$tlCSS

d. despair

G. delusion

46. W h i ~ h

ofthe

followmg

isNOT

oneof thesymptomsof depressioo?

~ d i ~ i n i s h e d interestin:aUacfrvities.

f a t i g ~ ()Tlossa energy.

...

.

~ d e c r ~ a b i 1 i t y to

thi,*or conCentrate

or

indecisiveness.

. .

;t:

e c w r ~ t

tnoughtofdeathof-suicide.

. . . : .

\.

,

.

.

4'1.

Wbicb

ofthe

foHoWi

ng

is

NOTone

oUbe

symptoms

of

mania?

.a. .inflatedself-esteem

f).;

i n f l a t e d s e l f ~ f i d e n c e

( ~ : ~ = : : a ~ : e : ~ ~ V . i t i e s

e.

exce$si.ve

pleasUrableactivitieswithhighpotefitialsforpainful

.'

conseqquences

.

4 8 . F ~ a t a l l o b o t o

I i l Y wasacommonpracticetotteat which

disorder

bltiijp

as

tY ' '. , .

depression.

f u e n i a .

.

manla..

.;K.

.

ADHO.

;L addiction.

.'49.. Thediffer

en.c.

ebetw.eeu

s

ehizoph-:-e

nia.

and

mania

is that

C9 the

tho

ught

processofsch

iZop

hrenia

is

disorganized

whitethe

thought

...'

process

ofmaniais g

oalc-directed.

X sehizopbrema

. ,

mcing

thought

wh

ilemaniadoesnot

A

s e f l ~ p b r e n bQlJavior

ot:lenieadstod

ire

consequenceswhilemania

. . 'doeS not; '. ' . , . .. ' . .

. . . K . s c h i z o p h r e ~ i a c ~ tr

eated w h i l maniaRothetr-eated

.medically.

A .

scbiiOphreniaishy

:peractive

while

maniais not.

. .

.Copyright

ClOG'

by

d T ~

An t g b ~ R e s e r v e

Co

nfidemtal use

by

re8isreredstUdents

only.Al

lotherusesordistributionare

prohibited.
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6/6

6

ame:

Student ID:

BIO 4220

Neuropsycb

Fall 07 Exam #3

Dr. David Tam

50. Tbe difference between ADD (attention deficit disorder) and

mania is tbat

the thought process

of

ADD

is

focused while the thought process

of

/.5J

mania is not

c

the racing thoughts

in

ADD are not focused

on

a single subject while

the racing thoughts in mania are focused on achieving a speci fic goal

even though that goal may be highly risky

.

/ ADD behavior often leads to dire consequences while mania does not.

ADD can be treated with medicine while mania not be treated

medically.

/ ADD is hyperactive while mania is not.

Copyright

2007

by

David Tam. All Rights Reserved. Confidential use

by

registered students only.

All

other uses or distribution are prohibited.

Documents

Neuropsych Test 3 Fall 07