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New Staging Proposal for Revision of Non-small Cell Lung Cancer: The Importance of New T Factors. Akif Turna, Necati Çıtak, Adnan Sayar, Nur Ürer, Atilla Gürses Yedikule Teaching Hospital for Chest Diseases and Thoracic Surgery, Istanbul, Turkey. - PowerPoint PPT Presentation
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New Staging Proposal for Revision of
Non-small Cell Lung Cancer:
The Importance of New T Factors
Akif Turna, Necati Çıtak, Adnan Sayar, Nur Ürer, Atilla Gürses
Yedikule Teaching Hospital for Chest Diseases and Thoracic Surgery, Istanbul, Turkey
Survival Rates in Resected Survival Rates in Resected Non-Small Cell Lung CancerNon-Small Cell Lung Cancer
Recursive Partitioning: Tekrarlayıcı Ayrıştırma
Text
n=100869
HYPOTHESISHYPOTHESIS
To test the Validity of New T To test the Validity of New T staging systemstaging system
Patients and MethodsPatients and Methods
✦Study Period : January 1995 - December 2007
✦Gender : 597 male, 52 female
✦ Mean Age : 56.9 (17 to 84) years
✦ Mean follow-up : 19 months
Preoperatif Work-upPreoperatif Work-up Thorax CT
‣ Bronchoscopy
‣ Cranial CT/MRI
‣ Whole body bone scintigraphy
‣ PET-CT (After 2003)
‣ Abdominal CT/USG
‣ Mediastinoscopy
‣ ‘Extended’ Mediastinoscopy/Mediastinotomy
SURGICAL ve PATHOLOGİC SURGICAL ve PATHOLOGİC PROCEDURES PROCEDURES
‣ Anterior / lateral torakotomi
‣ Lobectomy/Bilobectomy/Pneumonectomy
‣ Mediastinal lymph node dissection
‣ Pathologic evaluation: Hematoxylin-Eosin
Surgical Treatment and Surgical Treatment and Follow-upFollow-up
✦Lobectomy : 104(9 ‘sleeve’ )(75.4%)
✦Pnömonectomy : 22 (23.5%)
✦Bilobectomy : 10 (7.3%)
✦Wedge resection : 2 (1.5%)
✦TOTAL :138 patients were analyzed according to new
system
➡Follow-up : 21 months (mean)
➡Survival-Analysis: Kaplan-Meier / Log-rank test
Overall SurvivalOverall Survival
Text
Survival According to T FactorSurvival According to T Factor
T1
T2
T3T2T4
Survival of T2a and T2b Survival of T2a and T2b TumorsTumors
T2a
T2b
p=0.48
Survival of ‘New’ and ‘Old’ T3Survival of ‘New’ and ‘Old’ T3
Old T3
New T3
T2T2
p=0.61
ResultsResults
✦The prognosis of the patients with lung cancer
greater than 7 cm seemed to be similar to those with
T3 tumors.
✦However, The discrimination of proposed T2a and
T2b was not confirmed in our series