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New Treatments
New drug treatments
Chronotherapy
Lung cancer vaccine
Summary
New drug treatments
- Royal Marsden Hospital (London)- Specific mutations- Sophie (11y/o) → success
Chronotherapy
- Biological clock
- Circadian rhythms
- Signs + symptoms change
→ Chronotherapy
- Treatments at most optimal time
Chronotherapy
- Inconvenients:- Best time = night (often)- Mechanisms not well known
- P53 protein:- tumour suppressor- helps prevent mutation
- Personalised treatment
Lung cancer vaccine
Introduction
- Center of Molecular Immunology- 1st lung cancer vaccine- Cimavax- Not a cure:
- survival of patient- helps immune system- therapeutic vaccine
Advantages
- Cheap to produce + store- Few side effects
- nausea- chills- fever
How does it work ?
Cancer stimulates production EGFStimulates growth of cellsTumors multiply + grow uncontrollably
EGF : epidermal growth factor → body creates antibodies
Research
- Chemotherapy + ½ vaccine
- Trials showed:- More antibodies- Lived longer- Reduces cancer symptoms
This vaccine could be used for other types of cancer
Conclusion
- A lot of new treatments
- More and more effective
- Cancer has to be found early- However, treatments more effective on some
people than on others