NHS Fife Formula Abbreviated Drug List

7/30/2019 NHS Fife Formula Abbreviated Drug List

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THE FIFE FORMULARY

Abbreviated Drug List

APRIL 2004

Version 5

Fife Area Drug & Therapeutics Committeehas produced this formulary

for use in hospitals and general practicethroughout the Kingdom of Fife


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Contents

Chapter Page

Notes on Formulary Entries i

1. Gastrointestinal System 1

2. Cardiovascular System 2

3. Respiratory System 5

4. Central Nervous System 6

5. Infections 9

6. Endocrine System 12

7. Obstetrics, Gynaecology and Urinary-tract Disorders 14

8. Malignant Disease and Immunosupression 16

9. Nutrition and Blood 18

10. Musculoskeletal and Joint Diseases 20

11. Eyes 2112. Ear, Nose and Oropharynx 22

13. Skin 23

14. Vaccines 26

15. Anaesthesia 26

16. Poisoning 27

The formulary is regularly updated. Seewww.show.scot.nhs.uk/fifeadtcfor the current version.
http://www.show.scot.nhs.uk/fifeadtchttp://www.show.scot.nhs.uk/fifeadtchttp://www.show.scot.nhs.uk/fifeadtc


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Notes on Formulary Entries

New Layout

Drugs considered suitable for general use are have no shading surrounding them while drugsconsidered for use or initiation by or on the advice of specialists only are contained within ashaded box. These drugs should not normally be prescribed without the advice of a specialist.The restrictions on their use can be found in the A4 full Fife Joint Formulary which should beconsulted before prescribing.

Monitoring the safety and quality of medicines: New drugs under intensive surveillance(Black Triangle list)

Drugs that are under intense surveillance at the time of publication are indicated by theaddition of a black triangle next to the entryw. A black triangle will be assigned to a product ifthe drug is a new active substance. However, a product containing previously licensed activesubstances may also be monitored if it meets one or more of the following criteria:

a new combination of active substances;

administration via a novel route or drug delivery system; a significant new indication which may alter the established risk/benefit profile of

that drug.

The CSM/MCA wish to receive all suspected ADRs associated with these products in order toconfirm the risk/ benefit profile established during the pre-marketing phase. The black triangledrugs are monitored closely for a minimum of two years and the black triangle symbol is notremoved until the safety of the drug is well established.Yellow Cards can be found in:

British National Formulary (BNF)

Nurse Prescribers' Formulary

ABPI Compendium of Data Sheets and Summaries of Product Characteristics

MIMS Companion

Electronically throughwww.yellowcard.gov.uk

or by calling CSM Scotland on 0131 242 2919
http://www.yellowcard.gov.uk/http://www.yellowcard.gov.uk/http://www.yellowcard.gov.uk/


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1.6.4 Osmotic laxativesFletchers' Phosphate EnemaLactuloseMicralax Micro-enemaMovicol1.6.5 Bowel cleansing solutions

Hospital Use Only

Fleet Phospho-SodaKlean-PrepSodium Picosulfate (Picolax)

1.7 Local preparations for oraland rectal disorders

1.7.1 Soothing haemorrhoidal

preparationsAnusolLidocaine

1.7.2 Compound haemorrhodialpreparations withcorticosteroid

Anugesic HCHydrocortisoneScheriproct1.7.3 Rectal sclerosants

Hospital Use Only

Oily phenol injection

1.8 Stoma Care

For further advice on these products,contact the stoma care nurse at FifeAcute Hospitals NHS Trust.

1.9 Drugs affecting intestinalsecretions

1.9.1 Drugs affecting biliarycomposition and flow

Hospital Initiation Only

Ursodeoxycholic acid.

1.9.4 PancreatinCreonPancrex V


Nutrizym 22Pancrease HL2. CARDIOVASCULAR

SYSTEM

2.1 Positive inotropic drugs

2.1.1 Cardiac glycosidesDigoxin

Digoxin-specific antibody

Hospital Use Only

Digibind

2.2 Diuretics

2.2.1 Thiazides and relateddiuretics

Bendroflumethiazide


MetolazoneIndapamide

2.2.2 Loop DiureticsFurosemideBumetanide

2.2.3 Potassium-sparing diuretics

AmilorideAldosterone antagonistsSpironolactone

2.2.5 Osmotic diuretics

Hospital Use Only

Mannitol

2.2.8 Diuretics with PotassiumNo products are recommended.

2.3 Anti-arrhythmic drugs

2.3.2 Drugs for arrhythmias

Verapamil


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AmiodaroneDisopyramideFlecainidePropafenoneSotalol

Hospital Use Only

Adenosine (not includingAdenoscan)LignocaineMexiletine

2.4 Beta-adrenoceptor blockingdrugs

Atenolol

Bisoprolol w(suitable alternative to atenolol in thepresence of heart failure)


Carvedilol wNebivolol

Hospital Use Only

EsmololLabetalolMetoprololSotalol

2.5 Antihypertensive therapy

2.5.1 Vasodilator antihypertensivedrugs

Hydralazine

Hospital Use Only

Sodium nitroprusside

2.5.2 Centrally-actingantihypertensive drugs


ClonidineMoxonidine

2.5.4 Alpha-adrenoceptorblocking drugs

Doxazosin (not approved for BPH )

2.5.5 Drugs affecting the renin-angiotensin system2.5.5.1Angiotensin-converting

enzyme inhibitorsLisinoprilPerindoprilRamiprilTrandolapril

2.5.5.2 Angiotensin-II receptorantagonists

CandesartanIrbesartanLosartanTelmisartanValsartan

2.6 Nitrates, calcium-channel

blockers and potassium-channel activators

2.6.1 NitratesIsosorbide mononitrateGlyceryl trinitrate

Hospital Use Only

Isosorbide dinitrate(not includingtransdermal spray)

2.6.2 Calcium-channel blockersAmlodipineDiltiazemNifedipineVerapamil

Hospital Use Only

Nimodipine

2.6.3. Potassium-channelactivators

Nicorandil

2.6.4 Peripheral and cerebralvasodilators

2.6.4.1Peripheral vasodilators andrelated drugs

Naftidrofuryl oxalateNifedipine

2.6.4.2 Cerebral vasodilatorsNo products are recommended


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2.7 SympathomimeticsAdrenaline

2.7.1 Inotropicsympathomimetics

Hospital Use Only

DobutamineDopamineDopexamineIsoprenaline

2.7.2 Vasoconstrictorsympathomimetics

Hospital Use Only

Ephedrine hydrochlorideMetaraminolNoradrenalinePhenylephrine

2.8 Anticoagulants andprotamine

2.8.1 Parenteral AnticoagulantsHeparin

Low molecular weight heparins(LMWH)

Hospital Use OnlyDalteparinEnoxaparinTinzaparin

Hiridins and epoprostenol

Hospital Use Only

LepirudinEpoprostenol

Specialist Use Only

Fondaparinux w

2.8.2 Oral anticoagulantsWarfarinPhenindione (alternative wherewarfarin cannot be tolerated)

2.8.3 Protamine sulphateProtamine

2.9 Antiplatelet drugsAspirinClopidogrelDipyridamole

2.10 Fibrinolytic drugs

Hospital Use Only

StreptokinaseTenecteplase

2.11 Antifibrinolytic drugs andhaemostatics

EthamsylateTranexamic acid

Hospital Use Only

Aprotinin


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2.12 Lipid-regulating drugs

Anion-exchange resinsColestyramineColestipol

Clofibrate groupBezafibrateCiprofibrateFenofibrateGemfibrozil

StatinsAtorvastatinPravastainRosuvastatinSimvastatin

2.13 Local sclerosants

Hospital Use Only

Ethanolamine oleateSodium tetradecyl sulphate

3. RESPIRATORY SYSTEM

3.1 Bronchodilators

3.1.1Adrenoceptor agonists

3.1.1.1Selective beta2agonists

Short-actingSalbutamolTerbutaline

Long-actingFormoterolSalmeterol

3.1.1.2 Other adrenoceptorstimulants

Adrenaline

3.1.2 Antimuscarinicbronchodilators

IpratropiumTiotropium

3.1.3 TheophyllineAminophyllineTheophylline

3.1.4 Compound bronchodilatorpreparations

CombiventIpratropium 20micrograms/salbutamol 100 micrograms permetered inhalation

3.2 Corticosteroids

Inhaled steroidsBeclometasoneBudesonideFluticasone


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SystemicsteroidsPrednisoloneHydrocortisone

Compound preparations

Seretide

Symbicort

3.3 Cromoglycate relatedtherapy and leukotrienereceptor antagonists

3.3.1 Cromoglicate, relatedtherapy and leukotrienereceptor antagonists

Cromoglicate sodiumNedocromil sodium inhaler

3.3.2 Leukotriene receptorantagonists

MontelukastZafirlukast

3.4 Antihistamines,hyposensitisation andallergic emergencies

3.4.1 Antihistamines

Non SedatingCetirizine NEFLoratidineSedatingAlimemazineChlorphenamine

HydroxyzinePromethazine

3.4.3 Allergic Emergencies

Step 1 Adrenaline (Epinephrine)

(incl.autoinjector)And then call for helpAfter help calledChlorphenamineHydrocortisone

3.5 Respiratory stimulants andpulmonary surfactants

3.5.1 Respiratory stimulants

Hospital Use Only

Doxapram

3.5.2 Pulmonary surfactants

Hospital Use Only

Colfosceril palmitatePoractant

3.7 MucolyticsCarbocisteine

Mecysteine hydrochloride

3.8 Aromatic inhalationsMenthol crystals

3.9 Cough Preparations

3.9.1 Cough suppressantsPholcodine

3.9.2 Expectorant and demulcentcough preparations

Simple linctus

3.10 Systemic nasaldecongestants

No products are recommended

4. CENTRAL NERVOUSSYSTEM

4.1 Hypnotics and anxiolytics

4.1.1 Hypnotics

BenzodiazepinesNitrazepamTemazepam (tablets)

Zolpidem and zopicloneZolpidem tartrateZopiclone


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Chloral and derivatives

Specilaist Initiation Only

Chloral hydrateTriclofos elixir

4.1.2 Anxiolytics

BenzodiazepinesChlordiazepoxideDiazepamLorazepam

Other drugs for anxietyPropranolol

4.2 Drugs used in psychoses

and related disorders

4.2.1 Antipsychotic drugsTypical AntipsychoticsInitiation for psychosis should be byor in consultation with mental healthspecialist.

ChlorpromazineHaloperidolPromazineSulpirideTrifluoperazineZuclopenthixol dihydrochloride

Specialist Initiation OnlyBenperidol

ThioridazineZuclopenthixol acetate

Atypical Antipsychotics

Specialist Initiation Only

AmisulpirideClozapineOlanzapineQuetiapineRisperidone

4.2.2 Antipsychotic depotinjections

Typical Antipsychotics

Specialist Iniation Only

Flupentixol decanoateFluphenazine decanoateHaloperidol decanoatePipotiazine palmitateZuclopenthixol decanoate

Atypical Antipsychotics

Specialist Iniation Only

Risperdal Consta4.2.3 Antimanic drugsSpecialist Iniation Only

LithiumCarbamazepineSemisodium Valproate(Depakote)

Lithium products should beprescribed by brand name.

4.3 Antidepressant drugs

4.3.1 Tricyclic and relatedantidepressant drugs

TricyclicsAmitriptylineClomipramineDosulepinImipramineLofepramineTrimipramine

Related antidepressants

Trazodone

4.3.2 Monoamine-oxidaseinhibitors (MAOI's)


PhenelzineTranylcypromine

Reversible inhibitors of mono-amine oxidaseMoclobemide

4.3.3 Selective Serotonin re-uptakeinhibitors

CitalopramFluoxetineParoxetineSertraline


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4.3.4 Other Antidepressant DrugsMirtazapineReboxetineVenlafaxine


Tryptophan

4.4 Central nervous systemstimulants


Methylphenidate hydrochloride

4.6 Drugs used in nausea andvertigoBetahistineCinnarizineDomperidoneHyoscine hydrobromideMetoclopramideProchlorperazine

Hospital Use Only

ChlorpromazineCyclizineGranisetronHaloperidolMethotrimeprazineNabilone

OndansetronPromethazineTropisetron

4.7 Analgesics

4.7.1 Non-Opioid analgesicsParacetamol NPF/ NEFIbuprofen (low dose) NEFNefopam NEF

Compound analgesic preparationsCo-codamol 30/ 500Co-dydramol

4.7.2 Opioid analgesicsCodeine phosphate

CyclimorphDiamorphine

Dihydrocodeine (not including DF118Forte)Morphine sulphate (excluding MorcapSR)OxycodonePethidineTramadol oral

Hospital Use Only

Hydromorphone hydrochlorideFentanylTramadol injection

4.7.3 Neuropathic Pain

1st Line Amitriptyline

Nortriptyline2ndLine Gabapentin

Trigeminal neuralgia

CarbamazepineHospital Use Only

Phenytoin

4.7.4 Antimigraine drugs

4.7.4.1Treatment of acutemigraine attack

Naratriptan

SumatriptanZolmitriptan

4.7.4.2 Prophylaxis of migraine

PizotifenPropranolol

4.8 Antiepileptics

4.8.1 Control of epilepsy

CarbamazepinePhenobarbitolPhenytoinSodium valproate


Acetazolamide


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Clobazam (Schedule 11. Endorse SLS)ClonazepamEthosuximideGabapentinLamotrigineLevetiracetam wOxcarbazepine wPregabalinPrimidoneTopiramateVigabatrin4.8.2 Drugs used in status

epilepticusDiazepam

Hospital Use Only

Clonazepam

LorazepamParaldehydePhenytoin

4.8.3 Febrile convulsionsParacetamolDiazepam

4.9 Drugs used in parkinsonismand related disorders

4.9.1 Dopaminergic drugsCo-beneldopa (Madopar)Co-careldopa (Sinemet)Pramipexole wSelegiline

Hospital Use Only

ApomorphineCabergolineLisuridePergolideRopinirole

4.9.2 Antimuscarinic drugsBenztropineOrphenadrineProcyclidineTrihexyphenidyl

4.9.3 Drugs used in essentialtremor, chorea, tics andrelated disorders

Propranolol

Hospital Use Only

ChlorpromazineHaloperidolPimozidePrimidoneSulpirideTetrabenazine

Torsion dystonias and otherinvoluntary movements

Hospital Use Only

Botulinum A toxin-haemagglutinincomplex

4.10 Drugs used in substancedependence

Drugs used in alcoholdependenceDisulfiramAcamprosate

Drugs used for cigarette smokingBupropion (Amfembutamone) wNicotine ProductsFirst L ine: gum and patches

Drugs used in opioid dependenceMethadone 1mg/ml mixture

4.11 Drugs for dementia

Specialist I nitiation Only

Donepezil hydrochlorideGalantamineRivastigmine

5. INFECTIONS

See Fife Antibiotic guidance formanagement of common infectionsand serious infections in hospital.

5.1 Antibacterial drugs

5.1.1 Penicillins

5.1.1.1Benzylpenicillin andphenoxymethylpenicillin

BenzylpenicillinPhenoxymethylpenicillin


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5.1.1.2 Penicillinase resistantpenicillins

Flucloxacillin

5.1.1.3 Broad spectrum penicillinsAmoxicillinCo-amoxiclav

5.1.1.4 Antipseudomonalpenicillins

Hospital Use Only

TazocinTimentin5.1.2 Cephalosporins,

cephamycins, and other

beta-lactams

Cephalosporins and cephamycinsCefaclorCefalexinCefadrine

Hospital Use OnlyCefiximeCefotaximeCeftazidimeCeftriaxoneCefuroxime

Other beta-lactam antibioticsHospital Use Only

AztreonamImipenem with cilastatinMeropenem

5.1.3 TetracyclinesDoxycyclineMinocyclineOxytetracyclineTetracycline

5.1.4 Aminoglycosides

Hospital Use Only

AmikacinGentamicin

NeomycinNetilmicinTobramycin

5.1.5 MacrolidesErythromycinAzithromycinClarithromycin

Azithromycin should be used onlyfor indications which require itspowerful anti-chlamydial effect.

5.1.6 Clindamycin


Clindamycin(not i ncluding vaginalcream)

5.1.7 Some other antibiotics

Hospital Use Only

ChloramphenicolColistinFusidic acidLinezolid wTeicoplaninVancomycin

5.1.8 Sulphonamides andtrimethoprim

Trimethoprim

Hospital Use Only

Co-trimoxazoleSulfadiazineSulfadimidine

5.1.9 Anti-tuberculous agentsThese drugs will normally berecommended on specialist advice.

Rifampicin

Recommended for the prevention ofsecondary cases of meningococcalmeningitis and Haemophilusinfluenzae type b infection.

Hospital/Specialist Initiation Only

Ethambutol

IsoniazidPyrazinamideRifabutinRifater


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RifinahRimactazidStreptomycin

5.1.10 Antileprotic drugs


Dapsone

5.1.11MetronidazoleMetronidazole (not including vaginal gel)

5.1.12 QuinolonesCiprofloxacin (excluding 100mg tabletsfor uncomplicated UT I)

MoxifloxacinNorfloxacin

Ofloxacin

5.1.13 Urinary-tract infectionsNitrofurantoin

5.2 Antifungal drugsTerbinafineFluconazoleGriseofulvinItraconazole (not approved for fungal nailinfections)

Hospital Use Only

AmphotericinFlucytosineKetoconazole

Nystatin

Liposomal amphotericins arerestricted for use in systemicmycoses when toxicity precludes theuse of conventional amphotericin.

5.3 Antiviral agents

HIV infection

Nucleoside reverse transcriptaseinhibitors

Hospital Use Only

CombivirDidanosineLamivudineStavudine

ZalcitabineZidovudine

Protease inhibitors

Hospital Use OnlyAtazanavir wIndinavirRitonavirSaquinavir

5.3.2 Herpesvirus infections

5.3.2.1Herpes simplex andvaricella-zosterAciclovirFamciclovir (not approved for genitalherpes)

Valaciclovir

5.3.2.2 Cytomegalovirus infection

Hospital Use Only

CidofovirFoscarnetGanciclovir (including ophthalmicimplants)

5.3.4 InfluenzaZanamivir

Respiratory syncytial virus

Hospital Use Only

TribavirinPalivizumab w

5.4 Antiprotozoal agents

5.4.1 AntimalarialsUse on specialist advice

ChloroquineMefloquineProguanil

Hospital Use Only

PrimaquineQuinineHalofantrine


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For information on malariaprophylaxis or travel advice, healthcare professionals only can contactTel 0141 300 1130 or go towww.travax.scot.nhs.uk

5.4.8 Drugs for pneumocystispneumonia

Hospital Use Only

Co-trimoxazolePentamidineAtovaquone

5.5 Anthelmintics

5.5.1 Drugs for threadworms

MebendazolePripsen6. ENDOCRINE SYSTEM

6.1 Drugs used in diabetes

6.1.1 InsulinsSee BNF for details.

Includes NovoMix 30w,Insulinlispro, Insulin glarginewand Insulindetemirw. All insulins should beinitiated on hospital advice withcontinuation of prescribing inprimary care.

6.1.2 Oral antidiabetic drugs

6.1.2.1SulphonylureasGliclazideGlipizide

6.1.2.2 BiguanidesMetformin

6.1.2.3 Other antidiabetic drugs

Hospital Use Only

AcarboseNateglinidePioglitazone wRosiglitazone w

6.1.4 Treatment of hypoglycaemiaGlucoseGlucagon

6.2 Thyroid and Antithyroiddrugs

6.2.1 Thyroid hormonesLevothyroxine

Hospital Use Only

Liothyronine

6.2.2 Antithyroid drugsCarbimazole

Hospital Use Only

Aqueous iodinePropylthiouracil

6.3 Corticosteroids

6.3.1 Replacement therapyFludrocortisoneHydrocortisone

6.3.2 Glucocorticoid TherapyDexamethasoneHydrocortisonePrednisolone (including Prednesol)

Hospital Use Only

BetamethasoneCortisoneMethylprednisoloneTriamcinolone

6.4 Sex Hormones

6.4.1 Female sex hormones

6.4.1Female Sex Hormones

Tablets are considered the firstchoice formulation.

Patches may be appropriate in

Patients in whom there is a clinicalneed to avoid first passmetabolism of oestrogens


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Patients who cannot tolerate

tablets or express a strongpreference for patches.

Sequential Combined Therapy(cyclical)

1stLine - Tablets1st ChoiceC19 Progestogen

Elleste Duet(Estradiol/ norethisterone1mg/ 1mg or2mg/ 1mg). OR

Prempak-C(Conj equineoestrogen/ Norgesterol0.625mg/ 150microgram or

1.25mg/ 150microgram)

AlternativeC21 Progestogen

Femoston(Estradiol/ dydrogesterone.1mg/ 10mg; 2mg/ 10mg; 2mg/ 20mg)

2ndLine - Patches1st Choice

Evorel Sequi (Estradiol/Norethisterone50microgram/ 170microgram,MX Patch)

Continuous Combined Therapy

1stLine - Tablets1st ChoiceC19 Progestogen

Kliovance (Estradiol/norethisterone1mg/ 500micrigram)OR

Kliofem (Estradiol/ norethisterone2mg/1mg

AlternativeC21 Progestogen

Femoston-conti (Estradiol /Dydrogesterone1mg/ 5mg) or

Premique (Conj equine oestrogen/Medroxyprogesterone0.625microgram/ 5mg)

Premique Low Dose(Conj equineoestrogen/ medroxyprogesterone0.3mg/1.5mg)

2ndLine - Patches

1st Choice

Evorel Conti (Estradiol/

Norethisterone50microgram/ 170microgramMX Patch)Oestrogen only (unopposed)1st line Tablets1st Choice

Elleste-Solo (Estradiol1mg or 2mg)

Alternative

Premarin(Conj. EquineOestrogens0.625mg or 1.25mg)

2ndLine Patches1st Choice

Evorel Patch(Estradiol Twiceweekly25microgram;50microgram;75microgram;1

00microgram)

Alternative

FemSeven Patch(Estradiolweekly50microgram;75microgram;100microgram)

Other productsTiboloneRaloxifene Tablets

6.4.1.2ProgestogensNorethisterone

Hospital Use Only

Hydroxyprogesterone Hexanoate

6.4.2 Male sex hormones andantagonists

Hospital Use Only

Testosterone

Anti-androgensCyproterone

Hospital Use Only

FinasterideDutasteride w


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6.5 Hypothalamic and Pituitaryhormones and anti-oestrogens

6.5.1 Hypothalamic and anteriorpituitary hormones and anti-oestrogens

Anti-oestrogensClomiphene (Clomifene)

Anterior pituitary hormonesCorticotrophinsHospital Use Only

Tetracosactrin (Tetracosactide)

Gonadotrophins

Hospital Use Only

Chorionic gonadotrophinHuman menopausal gonadotrophinsUrofollitrophin

Growth HormoneSomatropin (recombinant humangrowth hormone)

Hypothalamic hormones

Hospital Use Only

GonadorelinProtirelinSermorelin

6.5.2 Posterior pituitary hormonesand antagonists

Posterior pituitary hormonesArgipressinDesmopressinHospital Use Only

Terlipressin

Antidiuretic hormone antagonists

Hospital Use Only

Demeclocycline

6.6 Drugs affecting bonemetabolism

6.6.1 Calcitonin and teriparatide

Hospital Use Only

Salcatonin (Calcitonin salmon)

Specialist I nitiation Only

Teriparatide w

6.6.2 BisphosphonatesAlso see sections 9.5.1.1 (Calciumsupplements) and 9.6.4 (Vitamin D)and Fife Guidance for Treatment ofOsteoporosis

Alendronic acidDidronel PMO

Risedronate

Hospital Use Only

Disodium etidronateDisodium pamidronateSodium Clodronate

6.7 Other endocrine drugs

6.7.1 Bromocriptine and otherdopaminergic drugs

Hospital Use Only

BromocriptineCabergoline

6.7.2 Drugs affectinggonadotrophins

Danazol

Gonadorelin analoguesBuserelin

Hospital Use Only

GoserelinLeuprorelinNafarelin

6.7.3 Metyrapone and Trilostane

Hospital Use Only

MetyraponeTrilostane


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7. OBSTETRICS,GYNAECOLOGY ANDURINARY TRACTDISORDERS

7.1 Drugs used in Obstetrics

7.1.1 Prostaglandins andoxytocics

Ergometrine

SyntometrineHospital Use Only

CarboprostDinoprostone (not including Propess-RS)Gemeprost

Oxytocin

7.1.1.1Ductus Arteriosus

Hospital Use Only

Alprostadil

7.1.2 Mifepristone

Hospital Use Only

Mifepristone

7.1.3 Myometrial relaxants

Hospital Use Only

RitodrineAtosiban

7.2 Treatment of vaginal andvulval conditions

7.2.1 Preparations for vaginalatrophy

1st line - creamsOrtho-GynestCream(Estriol 0.01%)OvestinCream(Estriol 0.1%)

2nd line - vaginal tablets

Vagifem(Estradiol 25microgram)

7.2.2 Vaginal and vulval infections

Fungal infectionsClotrmazoleMiconazoleNystatin

Oral fluconazole in a single dose of150mg is useful in the treatment ofrecurrent or resistant vaginalcandidiasis (see section 5.2).

Other infectionsAci-JelPovidone-iodineSultrin7.3 ContraceptivesSee BNF section

7.3.1Emergency ContraceptionLevonelle - 2

7.4 Drugs for genito-urinarytract disorders

7.4.1Drugs for urinary retentionand treatment of benignprostatic hyperplasia

AlfuzosinTamsulosinTerazosinIndoramin.Specialist Initiation OnlyFinasteride

Dutasteride

7.4.2 Drugs for urinary frequency,enuresis and incontinence

Tolterodine XLTrospiumOxybutynin

Duloxetine

7.4.3Drugs used in urologicalpain

Alkalinisation of urinePotassium citrate

7.4.4 Bladder instillations andurological surgery

Chlorhexidine

Hospital Use Only

Dimethyl sulfoxideGlycine


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7.4.5 Drugs for impotenceSildenafilAlprostadilApomorphine wTadalifil w

Restricted by NHS Medical ServiceRegs Schedule 11.

8. MALIGNANT DISEASEANDIMMUNOSUPPRESSION

8.1 Cytotoxic drugs

Drugs for cytotoxic-induced side-Effects

Methotrexate-induced mucositis andmyelosuppression

Hospital Use Only

Calcium folinate

Urothelial toxicity

Hospital Use Only

Mesna

8.1.1 Alkylating drugs

Hospital Use Only

BusulfanCarmustineChlorambucilCyclophosphamideEstramustineIfosfamideLomustineMelphalanChlormethine/ MustineThiotepaTreosulfan

8.1.2 Cytotoxic antibiotics

Hospital Use Only

AclarubicinBleomycinDactinomycin

DaunorubicinDaunoXomeDoxorubicinEpirubicinIdarubicin hydrochlorideMitomycinMitoxantrone

8.1.3 Antimetabolites

Specialist Use Only

Gemcitabine

Hospital Use Only

CladribineCytarabine

Fludarabine (w oral)FluorouracilMercaptopurineMethotrexateTioguanine

8.1.4 Vinca alkaloids andetoposide

Hospital Use Only

EtoposideVinblastineVincristineVindesineVinorelbine

8.1.5 Other antineoplastic drugs

Hospital Use Only

AmsacrineBortezomib wCarboplatinCisplatinCrisantaspaseDacarbazineDocetaxelHydroxycarbamideImatinib wIrinotecanPaclitaxelPentostatin

ProcarbazineTopotecanTretinoin


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8.2 Drugs affecting the immuneresponse

8.2.1 Proliferativeimmunosuppressants


AzathioprineMycophenolate mofetil w

8.2.2 Corticosteroids and otherimmunosuppressants

CiclosporinPrednisolone

Cyclosporin products should beprescribed by brand name.Hospital Use Only

Tacrolimus

8.2.3 RituximabHospital Use Only

Rituximab w

8.2.4 Other Immunomodulatingdrugs

Hospital Use Only

Interferon alfa (not approved for non-Hodgkin s lymphoma or malignant

melanoma)

8.3 Sex hormones and hormone

antagonists in malignantdisease

8.3.1 Oestrogen

Hospital Use Only

Diethylstilbestrol

8.3.2 Progestogens

Hospital Use Only

MedroxyprogesteroneMegestrol

8.3.4 Hormone antagonists

8.3.4.1 Breast cancer


(a) Neo-adjuvant therapy ofpostmenopausal breast cancer

LetrozoleTamoxifen


(b) Adjuvant therapy

Postmenopausal breast cancer

Tamoxifen

Anastrozole

Premenopausal breast cancer

Tamoxifen GoserelinAnastrozole + Goserelin


(c) Metastatic breast cancer

No prior adjuvant tamoxifen

LetrozoleTamoxifen

Prior adjuvant tamoxifen

LetrozoleExemestane w

8.3.4.2 Prostate cancer andgonadorelin analogues

Hospital Use Only

AminoglutethimideBicalutamideBuserelinCyproteroneFlutamideGoserelinLeuprorelin

8.3.4.3 Somatostatin analogues

Hospital Use Only

Octreotide


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9. NUTRITION ANDBLOOD

9.1 Anaemia and some otherblood disorders

9.1.1 Iron deficiency anaemias

9.1.1.1Oral ironFerrous fumarateFerrous gluconateFerrous sulphateSodium feredetate (Sytron)

Iron and folic acidPregaday9.1.1.2 Parenteral iron

Iron sorbitol

9.1.2 Drugs used in megaloblasticanaemias

Folic acid (400micrograms)Hydroxocobalamin

9.1.3 Drugs used in hypoplastic,haemolytic and renalanaemias

Erythropoietin

Hospital Use Only

Darbepoetin wEpoetin alpha and beta

Iron Overload

Hospital Use Only

Desferrioxamine

9.1.6 Drugs used in Neutropenia

Hospital Use Only

FilgrastimLenograstimMolgramostim

9.2 Fluids and electrolytes

9.2.1 Oral preparations for fluidand electrolyte imbalance

9.2.1.1Oral PotassiumPotassium chloride

Potassium Removal

Hospital Use Only

Calcium polystyrene sulphonateSodium polystyrene sulphonate

9.2.1.2 Oral sodium and water

Hospital Use Only

Sodium bicarbonateSodium chloride

Oral rehydration saltsDioralyte9.2.1.3 Oral bicarbonate

Hospital Use Only

Sodium bicarbonate

9.2.2 Parenteral preparations forfluid and electrolyteimbalance

9.2.2.1Electrolytes and waterSee BNF section

9.2.2.2Plasma and plasmasubstitutes

Hospital Use Only

Pentastarch infusionsDextran 40Dextran 70Gelofusine9.3 Intravenous nutritionUse only on specialist advice


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9.5 Minerals

9.5.1 Calcium and magnesium

9.5.1.1Calcium SupplementsCalcium carbonateCalcium chlorideCalcium gluconateCalcium phosphateCalcium SandozSandocal9.5.1.2 HypercalcaemiaSee section 6.6

9.5.1.3 Magnesium

Hospital Use Only

Magnesium hydroxideMagnesium sulphate

9.5.2 Phosphorus

9.5.2.1Phosphate Supplements

Hospital Use Only

Phosphate Sandoz9.5.2.2 Phosphate-binding agents

Hospital Use Only

Aluminium hydroxideCalcium acetateCalcium carbonate

9.5.3 Fluoride

Hospital Use Only

Sodium fluoride

9.5.4 ZincZinc sulphate

9.6 Vitamins

9.6.1 Vitamin A

Hospital Use Only

Retinol

9.6.2 Vitamin B groupPyridoxineThiamineVitamin B, CompoundVitamin B, compound, strong

Hospital Use Only

Pabrinex

9.6.3 Vitamin CAscorbic acid

9.6.4 Vitamin DAlfacalcidolCholecalciferol (colecalciferol)10microgram(400units) with (600mg calcium)CalciferolCalcitriol (not approved for use inosteoporosis and not including Calcijex)

Calcium with Ergocalciferol

Refer to the Fife Guidance on thetreatment of Osteoporosis forinformation on prescribing theseproducts for osteoporosis

9.6.5 Vitamin E

Hospital Use Only

Alpha tocopheryl acetate

9.6.6 Vitamin KMenadiol sodium phosphatePhytomenadione

9.6.7 Multivitamin preparationsAbidecVitamins capsules


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Vitamin and mineral supplementsand adjuncts to synthetic diets

Specialist initiation Only

Ketovite9.8 Metabolic disorders

9.8.1Drugs used in metabolicdisorders

Wilsons DiseaseHospital Use Only

Penicillamine

Carnitine deficiency

Hospital Use Only

L-carnitine

10. MUSCULOSKELETALAND JOINT DISEASES

10.1 Drugs used in rheumaticdiseases and gout

10.1.1Non steroidal anti-inflammatory drugs(NSAIDs)

Standard NSAIDs1st Choice IbuprofenAlternative Diclofenac

NaproxenMefenamic Acid is still used fortreatment of dysmenorrhoea

Cox II agentsCelecoxibMeloxicam

Use celecoxib 200mg twice a day in RA

patients only

10.1.2.2 Local corticosteroidinjectionsMethylprednisoloneTriamcinolone10.1.3 Drugs which suppress the

rheumatic disease process

Leflunomide wSulfasalazine

Hospital Use Only

AuranofinAzathioprineCiclosporinEtanercept wHydroxychloroquineInfliximab wMethotrexatePenicillamineSodium aurothiomalate

10.1.4 Drugs in the treatment ofgout

Interval treatmentAllopurinol

Acute attacksIndometacinEtoricoxib

Hospital Use Only

Colchicine

10.2 Drugs used inneuromuscular disorders

10.2.1Drugs which enhanceneuromuscular transmission


Pyridostigmine

Hospital Use Only

EdrophoniumNeostigmine

10.2.2 Skeletal muscle relaxantsBaclofenDiazepamQuinine


Dantrolene


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10.3 Drugs for the relief of soft-tissue inflammation

10.3.1Enzymes

Hospital Use Only

Hyaluronidase

10.3.2 Rubefacients

TransvasinMovelatCounter-irritant for post herpeticneuralgiaCapsaicin

PoulticesKaolin poultice

11. EYE

11.3 Anti-infective eyepreparations

11.3.1AntibacterialsChloramphenicolCiprofloxacinFusidic acidGentamicinOfloxacinPolyfaxPropamidine

11.3.2 AntifungalSee BNF section

11.3.3 AntiviralsAciclovir

11.4 Corticosteroids and otheranti-inflammatorypreparations

11.4.1CorticosteroidsBetamethasonePrednisolone Phosphate 0.5%(Predsol)


Betnesol NFluorometholoneMaxidex

Prednisolone acetate 1%(Predforte)

11.4.2 Other Anti-inflammatorypreparations

Nedocromil sodiumSodium cromoglicate

11.5 Mydriatics and cycloplegics

AntimuscarinicsCyclopentolateTropicamide


AtropineHomatropine

Sympathomimetics


ApraclonidinePhenylephrine

11.6 Treatment of glaucoma

Beta-blockers


BetaxololCarteololLevobunololTimolol

Prostaglandin analogues


Bimatoprost Latanoprost

Travoprost

Sympathomimetics


Brimonidine


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Carbonic anhydrase inhibitorsand systemic drugs


AcetazolamideDorzolamide

Miotics

Hospital Use Only

Pilocarpine eye drops

Combination products


Cosopt

Xalacom

11.7 Local anaestheticsTetracaineProxymetacaine

Hospital Use Only

Oxybuprocaine (Benoxinate)CocaineLidocaine and FluoresceinProxymetacaine and fluorescein

11.8 Miscellaneous ophthalmicpreparations

11.8.1Tear deficiency, ocularlubricants and astringents

CarbomersHydroxyethylcelluloseHypromelloseIlubeLacri-LubePolyvinyl alcohol

11.8.2 Ocular diagnostic and peri-operative preparations

Ocular diagnostic preparationsFluorescein

Hospital Use Only

Rose bengal

Ocular peri-operative drugs


FlurbiprofenKetorolac

Hospital Use Only

Acetylcholine chlorideApraclonidine eye dropsDiclofenac

11.9 Contact lensesSee BNF section

12. EAR, NOSE ANDOROPHARYNX

12.1 Drugs acting on the ear

12.1.1Otitis externaAluminium acetateAudicortBetamethasoneBetnesol-NClotrimazoleFramycetinGentamicinGentisone HCLocorten-VioformOtomizeOtosporinTri-Adcortyl Otic

12.1.3 Removal of waxCerumolSodium bicarbonate

12.2 Drugs acting on the nose

12.2.1Drugs used in nasal allergyAzelastineBeclometasoneBetamethasoneBudesonideFluticasone Nasal SprayMometasone Nasal SpraySodium cromoglicate


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12.2.2 Topical nasaldecongestants

SympathomimeticsEphedrineXylometazolineAntimuscarinicsIpratropium

12.2.3 Anti-infective nasalpreparations

MupirocinNaseptin12.3 Drugs acting on the

oropharynx

12.3.1Drugs for oral ulcerationand inflammation

Adcortyl in OrabaseBenzydamineCholine salicylateHydrocortisone pellets

12.3.2 Oropharyngeal anti-infective drugs

AmphotericinMiconazoleNystatin

12.3.3 Lozenges, sprays and gelsNot recommended.

12.3.4 Mouthwashes, gargles anddentifrices

Chlorhexidine

Hydrogen peroxideSodium chloride

12.3.5 Treatment of dry mouthArtificial saliva

13. SKIN

13.2 Emollient and barrierpreparations

13.2.1EmollientsAqueous creamCalmuridDimeticoneDiprobaseE45

Emulsifying ointmentHydromolKamillosan

Keri lotionOilatumParaffin, white softParaffin, yellow softUnguentum M

13.2.1.1Emollient bath additivesAlpha-Keri BathAveenoBalneumHydromol EmollientOilatumEmollient

13.2.2 Barrier preparationsDimeticoneSudocremZinc CreamZinc Ointment

13.3 Topical local anaestheticand antipruritic preparations

CalamineCrotamiton

13.4 Topical corticosteroidsTopical corticosteroids can beclassified according to their potency:Mildly potentEurax-hydrocortisoneFluocinolone acetonide 0.0025%(Synalar 1 in 10)Hydrocortisone base or acetate (0.1 -2.5%)Mildison

Moderately potentAlphadermClobetasone butyrate (Eumovate )Desoximetasone (0.05%) (StiedexLP)Fluocinolone acetonide 0.00625%(Synalar 1 in 4)

PotentBeclometasone dipropionate(Propaderm)Betamethasone dipropionate(Diprosone)Betamethasone valerateDesoximetasone (0.25%) (Stiedex)DiprosalicFluocinolone acetonide (0.025%)

(Synalar)Hydrocortisone butyrate (Locoid)Mometasone (Elocon)


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Hospital Use Only

Fluticasone cream only (Cutivate)

Very potentClobetasol propionate(Dermovate)

Topical corticosteroids withantibacterials

Mildly potentCanesten HCDaktacortFucidin HNystaform HC

Moderately potentTrimovatePotentBetnovate-CFucibetLotridermSynalar C13.5 Preparations for psoriasis

and eczema

13.5.1Preparations for eczemaIchthammol

13.5.2 Preparations for Psoriasis

Topical preparations

Alphosyl HCCalcipotriolCarbo-DomeCoal tarCocoisDithranolPolytar emollientPragmatarPsoralen paintPsorinSalicylic Acid

Oral retinoids for psoriasis

Hospital Use Only

Acetretin

13.5.3 Drugs affecting the immuneresponse

Hospital Use Only

CiclosporinMethotrexate

Tacrolimus OintmentPimecrolimus 1% cream

See Full formauley for prescribingrequirements

13.6 Preparations for acne

13.6.1Topical preparations foracne

Benzoyl peroxideClindamycin (not including vaginalcream)DuacErythromycinIsotretinoin gelQuinodermTretinoinZineryt13.6.2 Oral preparations for acneDianetteErythromycinMinocyclineOxytetracycline

Oxytetracycline is the tetracycline of

first choice in acne.

Hospital Use Only

Isotretinoin

13.7 Preparations for warts andcalluses

SalactolSilver nitrate

Anogenital WartsPodophyllotoxinPodophyllum

13.8 Sunscreens andcamouflaging preparations


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13.8.1Sunscreen preparationsRoc Total Sunblock(UVB-SPF >25)E45 Sunsunblock (UVB-SPF 15)Uvistatultrablock (UVB-SPF 30)Uvistatlipscreen (UVB-SPF 15)

13.8.2 CamouflagersCovermarkVeil13.9 Shampoos and other scalp

preparationsAlphosyl 2 in1CapasalCeanel ConcentrateCoal tarPolytar

Povidone iodineSelenium sulphide

13.10 Anti-infective skinpreparations

13.10.1Antibacterial preparations

13.10.1.1Topical onlyMupirocinSilver sulfadiazine

In Acute Trust prescribe on theadvice of the Tissue Viability Nurseonly

Hospital Use Only

Graneodin13.10.1.2 Topical and systemicChlortetracyclineFusidic acidMetronidazole (not including Rozexor

Zidoval )

13.10.2 Antifungal preparationsClotrimazoleEconazole )GriseofulvinMiconazoleNystaformNystatinTerbinafine

13.10.3 Antiviral preparations

AciclovirIdoxuridinePenciclovir13.10.4 Parasiticidal preparationsBenzyl benzoateCarbarylMalathionPermethrinPhenothrin

13.10.5 Preparations for minorcuts and abrasions

Magnesium sulphatePovidone-iodine

13.11 Skin cleansers andanitseptics

13.11.1Alcohols and salineIndustrial methylated spiritsSodium chlorideSurgical spirit

13.11.2 Chlorhexidine saltsChlorhexidineChlorhexidine/ Cetrimide

13.11.3 Cationic surfactants andsoapsSee BNF section

13.11.4 Chlorine and iodinePovidone-iodine

13.11.5 Phenolics

See BNF section

13.11.6 Astringents, oxidisers anddyes

Hydrogen peroxidePotassium permanganateZinc sulphate

13.11.7 Desloughing agentsAserbineHioxyl

Specialist Use Only

Varidase topical13.12 Antiperspirants

Aluminium chloride hexahydrate13.13 Wound managementSee BNF section


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Fife Acute Hospitals NHS Trust hasa Wound Management Formulary.Refer to this for advice on the use ofwound management products withinthe hospital setting.

14. IMMUNOLOGICALPRODUCTS ANDVACCINES

14.4 Vaccines and AntiseraSee BNF section

15 ANAESTHESIA

15.1 General anaesthetics

15.1.1Intravenous anaesthetics

Hospital Use Only

EtomidateKetaminePropofolThiopental

15.1.2 Inhalational anaesthetics

Hospital Use Only

DesfluraneEntonox/ EquanoxHalothaneIsofluraneNitrous oxideSevoflurane

15.1.3 Antimuscarinicpremedication drugs

Hospital Use Only

AtropineGlycopyrroniumHyoscine hydrobromide

15.1.4 Sedative and analgesic peri-operative drugs

15.1.4.1Anxiolytics andneuroleptics

Hospital Use Only

AlimemazineClomethiazoleChlorpromazineDiazepamLorazepamMidazolamTemazepam tablets

15.1.4.2 Non opioid analgesics

Hospital Use Only

DiclofenacKetorolac injectionTenoxicam injection

15.1.4.3 Opioid analgesics

Hospital Use Only

AlfentanilFentanyl injectionMorphinePethidineRemifentanil

15.1.5 Muscle relaxants

Non depolarising

Hospital Use Only

AtracuriumMivacuriumPancuroniumRocuroniumVecuronium

Depolarising

Hospital Use Only

Suxamethonium


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15.1.6 Anticholinesterases used inanaesthesia

Hospital Use Only

EdrophoniumNeostigmineRobinul-Neostigmine15.1.7 Antagonists for central and

respiratory depression

Hospital Use Only

DoxapramFlumazenilNaloxone

15.1.8 Antagonists for malignanthyperthermia

Hospital Use Only

Dantrolene

15.2 Local anaesthesia

Hospital Use Only

Tetracaine gelBupivacaineCocaineEmlaLevobupivicaine wLidocainePhenolPrilocaineProcaine

16. EMERGENCYTREATMENT OFPOISONING

See BNF Section for details

Documents

NHS Fife Formula Abbreviated Drug List