NIPER ASPIRANTS ACADEMY AHMEDABADpharmacol.weebly.com/uploads/3/7/8/8/3788687/gpat_sms-1.pdfsree: Biosynthesis of Alkaloids Atropine,NIcotine-Ornithine Coniine,Lycopodine,Piperidine

NIPER ASPIRANTS ACADEMY AHMEDABAD

Contact NAA at 08141811271 or mail us at [email protected] Page 1

GPAT SMS-2011

sari: mean cell Hb con.(MCHC)= (Hb in gms per 100ml / Vol. of packed RBC in 100ml) *100

NAA 18:44: MOHIT@NIPER 08141811271: bitoterol,pibuterol r rapidly actin selective beta2 agonist

bronchodilator. sameterol -slower onset so not used 4 acute attack of asthm

NAA 18:14: MOHIT@NIPER08141811271: REPAGLINIDE act by +ing release of insulin from pancreas.ETIDRONATE,PAMIDRONATE,TOLUDRONATE in paget's dss chara

NAA 17:52:

Bybu: How do we calculate mean cell Hb concentration (MCHC) Do reply

NAA 17:48: Bybu: whiskering is observed with the use of ---------------- Punches

ans - concave

NAA 17:46:

Bybu: Calculate the half life of a drug which is stable at pH 2.5. The rate constant is 5X10^-7 per sec at 25 degree. Drug obeys first order kinetics

NIPERITE: Citric acid is obtained from Aspergillus niger.

Apple is oxidised by O-diphenol oxidase.

#

NAA 08141811271:

NIPERITE...: ECD -most used detector in GC.

Abciximab used in Rheu Arthrit.

Zanamavir is used in....

Serch nd pas 2 ur friends if some ques r poste

#

NIPERITE...: osmotic delivery system uses noyes whitney equatn.

Bacillus stereothermophyllus used as biolog indicator for Moist heat steriln.

#

NIPERITE...: viagra is tradename of Sildenafil.

It is phosphodiesterases 5 inhibitor.

Punrnava is Boerhhevia diffusa used as diuretic.

#

NIPERITE...: nifedipine not used in arrhythmias

tamsulosin cause erectile dysfunction

#

NIPERITE...: all d friends plz u also post some good points for GATE so dat all can share it.ThanX.



Rock GATEPY2009!!!

#

NIPERITE...: Bromelains obtained from Pineapple is anti inflammatory

Rituximab used in respiratory synctial virus infection

#

NAA 2 08141811271:

NIPERITE...: practolol causes occulomucocutaneous reaction.

Sulphonamides show steven's Johnson syndrome.LCST is an eg of intelligent polymer for NDD

#

MOHIT@NIPER: chemical shift is measured in ppm

doxorubicin is cardiotoxic

arpi: Pimozide is used in Gilles de la Tourett's syndrome &ticks.

#

sagar: for which disease zidovudine is used?? hw it acts??

#

Ramkrishnan: For limitless such gate information check out our community GATEPY2009 in

Orkut...

ThanX MOHIT@NIPER for nice help to all Pharma grads!!!

#

MOHIT@NIPER08141811271: Polysorbate20 inactivate paraben

Quat ammon inactiv bt azolactin

Phenyl Hg nitrate by sulfide residue of rubber

GATEPY2009 rocks...

#

MOHIT@NIPER08141811271: Methotrexate-Antimetabolite-inhibits DHF reductase (S phase)

ADR-BMS, mucositis, crystalluria;leucovorin (folinic acid) rescue

#

MOHIT@NIPER08141811271: Doxorubicin adv effect-BMS-delayed CHF (dexrazoxane,free radical

trapper protects),alopecia,vesicant, radiation "recall"

Rock GATEPY2009!!!

#

netscape: Repaglinide nd nateglinide stim insulin scretn

Thiazolidinedione(glitazone-ci,tro, rosi, pio( PPAR gamma rec, inc insulin sensitivity, wt gain

#

netscape: Biguanide(metformin(inc glucore uptake anorexia

Sulphonylurea(tolbutamide, chlorpropamide, glibenclamide, glipizide(stim insulin secrtn,wt

gain???4

#

netscape: metronidazole is most extensively used in uti(intestinal amoebiasis(nd less in

leishmaniasis



shreya: oxytocin challenge test-used 4 utero-placental adequacy

*

NAA 13:06:

shreya: oxytocin challenge test- used 4 utero-placental adequacy.

*

NAA 13:00:

baku: Mosteller's eqtn?.. i dnt knw d ans.. plz post

*

NAA 12:47:

srav's: hi this is sravanthi 4m hyd..rock gate py2009

*

NAA 12:38:

nani: finger print region of IR-400 - 1500percm

group print region of IR -1500-4000 per cm

*

NAA 12:31:

kathan parikh: side effect of prolong use of atypical anipsycotic agent....? ans: "tardive

dyskinesia."

*

NAA 12:29:

kathan parikh: topical use of metronidazol is "psoriasis."

*

NAA 12:28:

kathan parikh: what is the topical use of metronidazol....?????

*

NAA 10:48:

MOHIT@NIPER08141811271: Kraft point is temp at d solblity of surfactant =to CMC

*

NAA 10:46:

MOHIT@NIPER08141811271: Zidovudine is anti HIV

Its acts by gettin converted to active triphosphates and competing with viral transcription process.

Rock GATEPY2009

sree: Biosynthesis of Alkaloids

Atropine,NIcotine-Ornithine

Coniine,Lycopodine,Piperidine alk-Lysine



Indole alk-Tryptophan

Phenylehylamine alk-tyr

NAA 17:58:

sree: Detectors used in IR-Thermocouple,Golay cell,Bolometer,Thermistor,Pyroelectric

NAA 08141811271:

shreya: imipenem gets rapidly hydrolysed by d enzyme dehydropeptidase I in renal tublr

cells.cilastatin is reversible inhibitr of d enzm. so combintn.

nani: carbamazipine&phenytoin sodium can be used for all types of seizures except absence

seizures

nani: ethosuxinamide is used in the treatment of absence seizures

nani: the drug of choice in trigeminal neuralgia is carbamazipine.

Vinit: churg strauss syndrome is observed with treatment of montelukast,zafirlukast,zileuton.

MOHIT@NIPER08141811271: Sulphur dioxide treatment given to type 2 glass to increase

resistance.

Heroin is the analgesic of last resort...

MOHIT@NIPER08141811271: Photoxicity of quinolones due to halogen at 8th position

Lomefloxacin has highest while sparfloxacin has lowest.

MOHIT@NIPER08141811271: Statins r associated with Rhabdomylosis & elevated serum

transaminase levels.

Fibrates r aryloxyamine derivatives...

ravi: clioquinol & haloprogin is a phenolic compd used in fungal infection Whitfield's oint'nt : 6% benzoicacid & 6% salicylicacid,use as anti fungal

ravi: In etiology of Alz' disease main responcible enz is CHOLINE ACETLY TRANSFERASE ( CAT)

ravi: Terbinafine,naftifine is a allylamine class of antifungal drug,act by squalene epoxidase inhibition Griseofulvin ctg Benzofuran ring

nani: different sizes of capsules is.....000,00,0,1,2,3,4,5.big size is 000,smallest size is 5 capsule...........

nani: Indian rhubarb shows strong blue(violet)fluorescence in U V region where as rhapnotic rhubarb shows blue flouresence in U V region..............

peru balsum is used in scabies.... colophony contains Abieatic acid which is phenanthrene derivatives known as Acid resin

Enrique: Schaffer Fulton Staining is endospore staining

#

NAA 20:29:



Enrique: Schaffer Fulton Staining is endospore staining

#

NAA 20:28:

Enrique: other than mycobaterium Nocardia sp. also gives +ve Acid fast staining test.

#

NAA 20:27:

Enrique: Phase contrast gives 2D image of detail account of internal structure while Differential

Interferance Contrast gives 3D images..

#

NAA 20:25:

Enrique: Conn's Focal Microscopy uses Laser Radiation.

SEM is used for studying 3Dsurface feature of sample, while TEM for studying 2Dinternal organs

#

NAA 08141811271:

Shagun-DIPSAR: Hi Everyone this Shagun from DIPSAR

#

geethika: hi guys thnqqqqqqqq very much for previous posts.........especially for MOHIT@NIPERh

for starting dis thread....gud n8 guys.......have a nice time

#

geethika: gold beater skin test- for identification of tannins.....,gambier flourecence test for

identification of pale catechu.........(gambier)

#

geethika: parasympatholytic drugs used in glaucoma...cyclopentoalate,tropicamide

#

rcl: chemical tests 4 tinevellin glycosides?

ravi: Dover's powder is mixture of Ipecac & opium used as a Expectorant.

Zilutone is a 5-Lipoxygenase Inhibtor

#

ravi: water, dilute solution, truesolution exhibit Newtonion flow

Ointment, emulsion,gels,colloidal dispersion exhibit Non newtonian flow.

#

ravi: Atovaquone and Proguanil are used in combination in a ratio of 2.5:1 for synergetic action

#

ravi: In nmr : J value(coupling costant) is between 1-20

tiku: acrylate polymar in that Eudragit E is non enteric while Eu. L&S is enteric

#



NAA 08:15:

sree: #

Phenytoin adr pheripheral neuritis,

Ehambutol adr optical neuritis..

pyridoxin is used for both drugs..

#

NAA 08:10:

sree: Phenytoin adr pheripheral neuritis,


pyridoxin is used for that..

#

NAA 08141811271:

kruti: antifungal prep- whitfield's ointment..... contains benzoic acid 6%, salicylic acid 6% in

petrolatum base.

#

Rockstar: PLZ FRIEND POST GOOD NOTES ONCE IN WEEK RATHER THAN RECIVING ONLY GOOD

NOTES BY FRIENDSWAKE UP DON'T BE AN IDIOT BOX.

FAST TRY SENDING NOTE

#

Rockstar: GOOD NIGHT GUYS

JAY HO GATEPY2009 KI

JAY SHREE KRISHNA

#

Rockstar: METRIFONATE IS RELATED TO INHIBITORS OF CHOLINE ESTERASE

#

Rockstar: LUMINESCENCE IS THE TERM APPLIED TO RE EMISSION OF PREVIOUSLY ABSORBED

RADIATION

#

Rockstar: HESPIRIDIN AND RUTIN ARE FLAVANOID GLYCOSIDE OCCURING IN CITRUS FRUITS

#

Rockstar: CITRUS FLAVONOID ARE RICH IN HESPIRIDIN.

sree: Chemical shift- expressed in ppm(parts per million)

TetraMethylSilane(TMS) is reference compound and shows resonance exactly at 60 MHz

NAA 18:42: sree: In NMR 60MHz-radiofrequency 14092guass-magnetic field strength

In ESR 9500 to 35000MHz-Microwave frequency 500 to 3400guass-magnetic field



NAA 08:35: geethika: chlorpheniramine & cetrizine dextro isomers r active.....gud mng

NAA 08141811271: tiku: this are derive form cocaine,hyoscymine- ornithine

colchicine- phenylalanin emetin- dopamine

NAA 2 08141811271: tiku: acrylate polymar in that Eudragit E is non enteric while Eu. L&S is enteric

sree: # Phenytoin adr pheripheral neuritis,

Ehambutol adr optical neuritis.. pyridoxin is used for both drugs..

sree: Phenytoin adr pheripheral neuritis, Ehambutol adr optical neuritis.. pyridoxin is used for that..

NAA 3 08141811271: kruti: antifungal prep- whitfield's ointment..... contains benzoic acid 6%, salicylic acid 6% in

petrolatum base

ravi: sys lupus ery.is cause

by:procainamide,chlorpropramide,barbiturates,methyldopa,INH,phenytoin,hydralazine,sulphonami

de,IFN-alpha

#

ravi: Malarial relapse due to Hypnozoites.

Erythromycine act by Motilin receptor by these way it increase gastric contraction&promote intes.

motility

#

NAA 2 08141811271:

ravi: sparfloxacin and moxifloxacin r prolong the QT interval so contraindicated to the patient

taking Anti arr, drug

#

ravi: Sulfasalazine is reserved for Crohn disease.

Sulfa drug is given with Sodium bicarbonate to decrease the Crystalluria.

#

ravi: ZPTO (Zinc pyrithion) is an anti dandruff agent used in Shampoo.

Sulfasalazine is only sulfa drug that has an anti inflammatory action

Sam: welcome back MOHIT@NIPER without u the community was sleeping.thanX to ravi,geethika,sree they kept posting...

MOHIT@NIPER u rock man! i wanna meet u once! MOHIT@NIPER08141811271: Non thiol ACE inhibitor is enalapril

due to absnce of this thiol group it lacks s/e of rash & loss of taste. Plz post questn.GATE is near ravi: Anti diabeticdrug that cause GI disturbance:- Acarbose



Antidote for xanthine alkaloid :- Barbiturates ravi: Teratogenicity is most possible during the 1st trimester of the pregnancy

Statin were initially isolated from?Ans please. ravi: In methyl alcohol poisoning there is CNS toxicity,cardiac toxicity &optic nerve atropathy due

to Formaldehyde and formic acid

ravi: fosinopril is a Phosphate grup ctg ACE inhibitor. Piroxicam is a single dose NSIADS. Rachana: Sodium valproate is an antiepileptic & mood stabilizer drug Clozapine is used in Refractory schizophrenia.

tiku: NO) is a ubiquitous mediator with diverse functions. It is generated from L-arginine by nitric oxide synthase (NOS), an enzyme that occurs in en tiku: NO) is a ubiquitous mediator with diverse functions. It is generated from L-arginine by nitric

oxide synthase (NOS), an enzyme that occurs in en geethika: main adr of verapamil is constipation.it shudn't be taken wid digoxin..plz post questions.be active...

sree: ampherometry-diffusion cur Vs vol of titrant. Non polarisable electrode-saturated calomel elect, polarisable elcts-dropping mercury,platinum electrode sree: potentiometry-potential Vs vol of titrant

conductometry-conductivity Vs vol of titrant polarography-diffusion current Vs voltage sree: determination of conductivity-Whatstone bridge circuit and conductivity cell is used.

conductivity cell is made up of platinum&stainless steel

rcl: the monoclonal antibody used in asthama OMALIZUMAB[antiIgE] ...ramana chary

Ruchi: isolation of statins: Mevastatin-Penicillium species and metabolised to Pravastatin. Lovastatin-Aspergillus and Monascus species.

suja: Emetine is predominant alkaloid of C.ipecacuanha. In the official bioassay of erytromycin the stain used is Micrococcus luteus

Ravi: Tretnoin is a Biological responce modifier used in cancer. Major causative organism for UTI is E.Coli.

ravi: Mupirocin is obtained from pseudomonas spp.

Methocinchonan ring is present in QUININE Ethyl cellulose is water insoluble colloide.

shreya: Dexamethasone supression test is used 4 diagnosis of cushing's syndrome

gate _warrior: isoniazid(anti TB drug) is metabolized to acetylhydrazine(which is responsible for its hepatotoxicity)

Enrique: Hiii friends...

I m Shahbaz Eqbal, nicknamed Enrique from NIPS Bhopal... My cell no. is 919893681643. I will be pleased to sort ur queries

Enrique: Sulfasalazine=ASA+Sulfapyridine Mesalazine=ASA+ acrylic acid Olsalazine= ASA+ASA

Balsalazine= ASA+ Alanine



NAA 21:05: Enrique: Dihydro folate Reductase Inhibitor(also toxic to human)

trimethoprim

Pyrimethamine Methotrexate

rcl: in MUSTARD;sinigrin(pot.myronate) in presence of water,enzyme myrosin gives volatile oil(allyl isothiocyanate) wich is resp. 4 its emetic action

rcl: Ramana chary(ram's) PDE-4 inhibitor used in asthama& COPD is ROFLUMILAT

rcl: Ramana chary: OCTEOTIDE is used in treatment of Zollinger-Ellision syndrome(gastrin produsing tumour).frns keep on posting rock

geethika: phynytoin follows non-linear pharmacokinetics

geethika: phenytoin can't be used for absence seizures.primary metabolite of dis is 5-(hydroxy phenyl)-5-phenyl hydantoin.

sree: Rotofil-fill pellets into capsules. Elancofil/accofil-fill powders into cap.

Rotosort-To sort out filled & unfilled cap. Rotoweigh-cap's weig

Rockstar: metabolite of spironolactone is canrenone

sumatriptan is 5-ht1d agonist used in migrane

Rockstar: bosentan is endothelin receptor antagonist used as anti hyper tensive Rockstar: mabefradil block both l and t type calcium channel

Bybu: Test organism used for microbiological assay of Kanamycin Sulphate Bacillus pumilus and Staphylococcus aureus Post questions friends

Bybu: List of Diseases and ailments which a drug may not purport to prevent or cure or makes

claim to prevent or cure is given under Schedule J

Bybu: Gas cells which is used for sampling of gases in IR is made up of KBr Colchicine is used in the treatment of Gout

Bybu: The shape of polagraphic curve is S-shaped Vitamin D2 is 22,23-dihydro-5,6-cis-ergocalciferol

shreya: advrs efect of procainamide is torsedesdpointees,agranulocytosis,aplastic anemia,systemic lupus erythrometosus. its metblism is by acetylation

shreya: Quidine prolongs t1/2 of propafenone nd inhibits conversion of codiene 2 morphine.

shreya: Ergometrine is used in diagnosis of variant angina.

shreya: hi sree, u 4get d HLB of antifoaming i.e 1-3. ok.



sree: for eg. SLS has 12 CH2 groups and each has 0.475 weight. It contains Na and sulfate ions so

mol wt of hydrophilic grp is 38.7-(0.475 x12) +7=40.

sree: HLB value =

sum of hydrophillic group number - sum of hydrophobic group number(CH2) +7 NAA 2 08141811271:

sree: HLB values 3 to 6 : w/o agent 7 to 9 : wetting agent

8 to 18 : o/w agent 13 to 15 : detergent 10 to 18 : solubilizing agents

Ravi: Gibbs spray reagent(2,6 dibromo quinone chloramide)-for phenol Carr'sprice reagent (antimony-3-chloride)for vitA &vitD zwikker reagent-Ans pls

NAA 4 08141811271:

Ravi: Very soluble-10000ml

NAA 5 08141811271: Ravi: In NMR pascle's triangle gives intensity of different peaks

Ravi: Shift reagent r chemical compd that r used for decoupling in NMR. Example:Europium(dpm)3,Eu(fod)3,tris(dipivalomethanato)europium

ravinder reddy:

01-

November-

2010

ravinder reddy: polypeptide chainnumber canbe

identified by treatment of proteins with dansyl

chloride;sangers reagent=1-flouro-2,4-

dintrobenzene

NIPER Aspirant Academy

NAA @ 08141811271:

31-

October-

2010

NAA @ 08141811271: RING analogues:

Acyclovir,ganciclovir,Ribavarin=Purine analogs

Fluorouracil,Idoxuridine=Pyrimidine

Foscarnet=Non nucleotide


NAA @ 08141811271: 31-

http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40



October-

2010

NAA @ 08141811271: METABOLITES:

Azathioprim=6-mercaptopurine

cortisone=hydrocortisone

diazepam=oxazepam

primodone=phenobarbitone

propranolol=4hydrxyproprno


NAA @ 08141811271:

29-

October-

2010

NAA @ 08141811271: SIDE CHAINS:

chlorpromazine=propyldimethylamino

thioridazine=piperidine

Fluphenazine=Piperazine

Promethazine=ethyl diethyl amine


NAA @ 08141811271:

29-

October-

2010

NAA @ 08141811271: targeted molecule n

starting material

Glutethimide=benzyl cyanide

Guanethidine=azocaine

Methotrexate=2456-Tetraminopyrimidine


ravinder reddy:

28-

October-

2010

ravinder reddy: coombs test=anti

globulin;widal=typhoid;khan

test=syphilis;VDRL=YELLOW FEVER


NAA @ 08141811271:

27-

October-

2010

NAA @ 08141811271: Sarsapogenin=starting

material of testosterone

stereochemistry of pencillin 3S:5R:6R

tetracyclin undergoes epimerization at C4 position


Ramana: 26-

October-

http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40



2010

Ramana: B-DNA:fulfil the wastson n crick model

criteria,right handed,diameter=20A,10

basepairs/turn,6degree base tilt; Ramana.


NAA @ 08141811271:

26-

October-

2010

NAA @ 08141811271: glucose galactose = C4

epimers

glucose mannose = C2 epimers

alpha beta forms of D Glucose = ANOMERS


NAA @ 08141811271:

26-

October-

2010

NAA @ 08141811271: glucose galactose are C4

epimers

glucose mannose are C2 epimers

alpha beta forms of D Glucose are ANOMERS


ravinder reddy: 24-October-2010

ravinder reddy: clozapine=dibenzodiazepine;loxapine=dibenzo-

oxazepine;clothiapine=dibenzothiazepine;concentrate on heterocyclic rings presentindr



ravinder reddy: cold=2-8'c;cool=8-25'c;room=25-30'c;warm=30-40'c;excessive

heat=>40'c.plz read isotonic ,child dose,suppository calculations


NAA @ 08141811271: 24-October-2010

NAA @ 08141811271: hello GPAT qualifiers, in AP dis time 3473 seats r going 2 b filled

through web counsling, acording to info presnt in apsche,so dnt wor


NAA @ 08141811271: 23-October-2010

NAA @ 08141811271: natural camphor=Dextro rotation

bent pedicel=Datura

ergot in UV light =blue flourescence



ravinder reddy: glucose and galactose are epimers to each other with reference to....?

A)C2 B)C3 C)C4 D)C1;just concentrate on thesterioisom

http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=40http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50





ravinder reddy: millons test=tyrosine;hopkins kole test=tryptophan;molisch

test=glycoprotein;newmanns test=phosphoprotein


NAA @ 08141811271: 22-October-2010

NAA @ 08141811271: hello GPAT qualifiers.. Web Counsling dates :

29th certificate verifcaton,

30th optn entry,

3rd seat alotmnt.hope u all wil gt gud Col


NAA @ 08141811271: 22-October-2010

NAA @ 08141811271: hello GPAT qualifiers.. Web Counselling notification has come in

AP,see EENADU,SAKSHI for details. Prepare ur certificates ready.



ravinder reddy: chloroquine-user in rheumatoid arthritis,D-isomer of penicillamine used as

antirheumatoid drug,methotrexate has immuno supreesant


NAA @ 08141811271: 21-October-2010

NAA @ 08141811271: nabumetone=6methoxy2Napthyl aceticacid

Prazosin=Quinazoline

tolazoline=imidazoline

NAA @ 08141811271: 21-October-2010

NAA @ 08141811271: nabumetone=6methoxy2Napthyl aceticacid

Prazosin=Quinazoline

tolazoline=imidazoline


NAA @ 08141811271: 20-October-2010

NAA @ 08141811271: To join in NIPERs google sms channels Send as

ON NIPER_ACADEMY to

+919870807070

ON NIPERACADEMY to

+919870807070



ravinder reddy: ash contents simply represents inorganic salts, total ash usually consist of

carbonates,phosphates,silicates and silica.



ravinder reddy: PDE5 inhibitor-sildenafil,not only inhibit PDE5,but also inhibit the

PDE6,causes visual loss.

http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=50http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60





ravinder reddy: FLOURIMETRY:CN,SO3H,NH4+ groups does not affect the flouriscent

intensity;NH2,NHR,NR2 increases flourescent intensity.



Frds,dont delete these points,keep one notebook separately for these,realy it wil help at

final.RAVINDRA



synonyms:colchicum=meadow saffron seeds,ephedra=ma huang,cinchona=jesuit's

bark;stramonium=thorn apple.ravindra



indian senna-tinnevelleu senna.alexandrian senna-cassia senna,senna pods-sennae

fructus,rhubarb-revandchini,cascara-chittem bark frm RAVINDRA


NAA @ 08141811271: 17-October-2010

ZPTO (Zinc pyrithion) is an anti dandruff agent used in Shampoo.

Sulfasalazine is only sulfa drug that has an anti inflammatory action


NAA @ 08141811271: 17-October-2010

practice SHARGEL Biopharmaceutics calculations, mainly 1st ,zero order given at the back ot

the book


NMR-TMS is reference standard,at 0.5% concentration,,number of adjacent protons=multiplicity

of the peaks.RAVINDRA


NAA @ 08141811271: 16-October-2010

To join in NIPERs NEW google sms channel Send as

ON NIPERACADEMY to

+919870807070

pass it to all who r aiming for GPAT/NIPER


NAA @ 08141811271: 16-October-2010

V d NIPERites r going2launch a NEW channel on this DASSERA Bz of our juniors

demnd,2receiv more info thru sms, subscribe 2othr channel also



NMR-study of spin changes at the nuclear level,radio frequency is used as light source.frm

ravindra

http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=60http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=70http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=70http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=70




NAA @ 08141811271: 15-October-2010

IMViC test used for detecting enteric bacteria

Yersinia pestis causes Bubonic plague

read antibiotics assay organisms well

NAA @ 08141811271


NAA @ 08141811271: 15-October-2010

holder method= 62.8

pasteur method= 71.6

Fiducial limit 95-105%

simple staining=methylene blue, basic fuschin

heaf test for TB

NAA @ 08141811271



flucanozole-drug of choice of fungal meningitis, flucytosine-prodrug,its active metabolite-5

fluoro uracil.frm ravinder


Ramana: 14-October-2010

.PDE3I-amrinone,cilostazol,enoximone;PDE4I-

rolipram,roflimilast,luteolin,mesembrine;PDE5I-sildenafil, tadalafil. Ramana.



phosphodiestarage inhibitors.nonselectiv-methylated xanthins;Selectv PDE1I-

vinpocetine;PDE2I-anagrelide.Ramana



ZYDOVUDINE IS THE ANALOGUE OF THYMIDINE,ZALCITABINE IS THE

HOMOLOGUE OF THECYTOCINE,DIDANOSINE IS THE ANALOGUE OF THE

DEOXYADENOSINE FRM RAVINDRA



block water fever-chloroquine,B-agonists-tremaurs.



edroponium-diagnosis of myastania gravis, ecathiopate-anticholinesterage drug used in the

treatment of glaucoma.frm Ravindra


NAA @ 08141811271: 12-October-2010

cysteine=Nitropruside test

sucrose=Non reducing sugar

Ovalbumin,Glutelin=Storage protein.

Sakaguchi test=Arginine,Inulin=Fructose. NAA @ 08141811271





NAA @ 08141811271: 12-October-2010

Rotosort is machine used to sort out filled capsules.Tamoxifen=Selective Estrogen Receptor

Modulator(SERM) treats breast cancer. NAA @ 08141811271



widal test-typhoid,dick& ELEK tst-diphteria,mountex tst-TB ,ducry tst-hemophilia;cooms

tst-brucellosis,rosewater tst-rh.arthritis. Ramana


NAA @ 08141811271: 11-October-2010

Gossypol male contraceptive causes hypokalaemia.

Transformation=Up take of nacked-DNA,

Transduction=by Bacteriophase. NAA @ 08141811271


NAA @ 08141811271: 10-October-2010

uptake of Glucose=facilitatd difusion,

Bile+HNO3=Gmelin test,Aminoacid+Benzoic acid=Hippuric acid,

NiemanPickDisease=Spingomylnase.NAA @ 08141811271


NAA @ 08141811271: 10-October-2010

Riboflavin=Isoalloxazine,

alpha carotene=antioxidnt,

Lascorbic acid is derivtiv of L Glucose,

folicacid=pteridine,

Zymogen=inactive NAA @ 08141811271



levels of protein structure 1ry-seqnce of a.a,2ry-structural patterns,3ry-3D structr (folding) of a

polypeptd. Ram's.


NAA @ 08141811271: 09-October-2010

do INAMDAR book once then u ll hv complete understanding abt question paper.

NAA @ 08141811271


Dsntgratn tm 4 tabs:

Dispersbl-3min

Uncoatd-15m

Filmcoatd-30m

Sugarcoatd-60m

Soft capsl-60m

Hard Capsl-30m.Ram's


NAA @ 08141811271: 09-October-2010

mevastatin=Penicillium citrium.




lovastatin=Aspergillus terreus.

Daunorubicin=Streptomyces peucetius


NAA @ 08141811271: 08-October-2010

Plastic flow:floculated particles in concentrated suspntion

Pseudoplastic polymers in solutn

Dilatant:suspention of defloculated prticles



..distngsh b/w clove n clove stalk powdrs,clove n mother clove. Horse shoe shaped stone cells

present in.....? Ram's.



Hi. GRamana(Ram's).



vch hypolipdmc drg has beta-lctum rng?

a)gugulipid

b)cefixime c)ezetimibe d)atorvasttn.Water dnsty at 4'C=1.0

Ramana.



.Lignifd trichomes- nuxvomica, stropanthus.Rwlfia does nt hv stone cells(sclrds) bt its

adultrants cntn them. Ramana.


NAA @ 08141811271: 06-October-2010

hey dont worry dudes v r back again in ur mobile., due to network problem u dint receive

msgs . Keep moving.... From KS


NAA @ 08141811271: 05-October-2010

Tell to ur juniors to join in our academy. to join in channel type "ON NIPER_ACADEMY" to

+919870807070



..S-Thalidomide is teratogen.R is sedative; see d ingrdnts impart pungency 2 zinger, capsicum.

Ramana


... Hi frnds. Der was some prblm in ggle chnnl in snding msgs. Nw nwds u'l get msgs. Ramana


NAA @ 08141811271: 30-September-

2010

new aspirants can join in our academy at




Hyderabad or Warangal... Coaching is same at all branches. Pass this 2 all 2 get more msgs to


NAA @ 08141811271: 30-September-

2010

http://labs.google.co.in/smschannels/subscribe/NIPER_ACADEMY

u can also join this channel through net.


NAA @ 08141811271: 30-September-

2010

To join this GPAT channel ask ur friends or juniors to send

'ON NIPER_ACADEMY' to 09870807070

More they join more they get to know..


NAA @ 08141811271: 29-September-

2010

Syneresis:shrinking of gel & liq is pressed out

Bleeding:relese of oil/water frm ointmnt base

Imbibition:tak up of watr by gel widout incres in


NAA @ 08141811271: 29-September-

2010

Plastic flow:floculated particles in concen suspnsion

Pseudoplastic:polymers in solutn

Dilatant:suspention containing defloculated prticl


NAA @ 08141811271: 29-September-

2010

senna-paracytic stomata,

coca-dicytic stomata,

fennel-anomocytic,

tropane alkaloid-anisocytic stomata,


NAA @ 08141811271: 28-September-

2010

active constituents % ergot 0.19

nuxvomica 1.2 physostigma 0.15 ephedra 1

opium 9.5

ipecac 2

cinchona 6


NAA @ 08141811271: 28-September-

2010

hydrodistillation=extraction of volatile oil Enfleurage=perfumes Eucelle=citrus oil




Dill=apiole

fennel=anethole

chenopodium=ascaridole


Ramana: 27-September-

2010

...Thallqn test: qnine +Br water+ammonia-> green colr. Ramana


NAA @ 08141811271: 26-September-2010

Osmotic diuretic mannitol used in CHF,Tachyphylaxis associated with ephedrine,Asthma

aggravated by propanolol,metronidazole=intestinal amoebiasis


NAA @ 08141811271: 26-September-2010

Anastrozole inhibits aromatase,Minoxidil used in baldness,Nicorandil is potassium channel

opener,Verapamil enhances chloroquine transport. KS....


NAA @ 08141811271: 26-September-

2010

Adenosine and Histamine are the endogenous anticonvulsants ,Astemazole,loratidine etc are

anti histaminics that lacks sedative actions,Learn IR r


NAA @ 08141811271: 25-September-

2010

zone 1 temperate. Zone 2 subtropical. Zone 3 hot dry climate zone. Zone 4 humid climate.

India belongs to zone 4.

Montox test=TB,


NAA @ 08141811271: 25-September-

2010

Turpentine=alpha pinene,Eucalyptus=cineole,Allicin=garlic,Artemesin=Sesquiterpene

lactone,Gaultheria=Rheumatism,shellac=sub coating


NAA @ 08141811271: 25-September-

2010

new aspirants can join in our academy at

Hyderabad or Warangal... Coaching is same at all branches. Pass this 2 all 2 get more msgs to

u


NAA @ 08141811271: 23-September-

2010

visit our academy website in net..new guys can register through net also for admission in

academy.or contact ur seniors for guidance





NAA @ 08141811271: 23-September-

2010

anticancer drug-adrenal hormone synthesis inhibitor-trilostane,monoclonal antb-

rituximab,tarstuzumab,alemtuzumab,


NAA @ 08141811271: 23-September-2010

crystal growth inhibitors PVP PEG., APOC=agglomerative phase of communition.em problems

in biopharm


NAA @ 08141811271: 22-September-2010

DLVO theory describe charge stabilization,ClenbuterolB2 agonist taken by sportsman.,practice

all beta blockers structures

NAA @ 08141811271: 22-September-2010

minoxidil -adverse efect z hypertricosis so usd in baldnes. Vancomycin-red man syndrom;see

wch GABA,5HT-sub cls receptors are fast acting


NAA @ 08141811271: 21-September-2010

remember all isomers

S captopril, Z sulindac, S ibuprofen, Z doxepin, S propranolol, Z thiothixene, d ethambutol, l

ephedrine, l hyosyamine


NAA @ 08141811271: 21-September-

2010

caffine=murexide test.PAFantgnist=Gingko.

St.Jons wrt=MAO inhib.capusule smlst siz-5.

largst 000.

bloomStrngth=150-250g


NAA @ 08141811271: 20-September-

2010

remember,,, Dronabinol=apetite stimulant during AIDS,Clioquinol=Alzhemier's

disease,Grape seed=Naringin,Morphine=phenanthrene,Fiehe's test=honey


NAA @ 08141811271: 20-September-

2010

Doxepin used for insomnia,Imiquimod for: Actinic Keratosis,Topiramate is an anticonvulsant

,drugs causing fanconi are tetracyclines & Ifosfamide.


NAA @ 08141811271: 20-September-

2010

SIZE of microemulsion:5-200 nM

capusule:smallest size-5 hv capcity 0.15ml

largest 000-1.15ml(1000mg)

bloom strength of cap. is 150-250gm





NAA @ 08141811271: 19-September-

2010

Ecothiophate an organophosphate drug is watersoluble &some times used in glaucoma.

Alkanes deal with free radcl substn


NAA @ 08141811271: 19-September-

2010

CNS:2 type of receptors:-

1)Excitatry receptors-NMDA,AMPA,Kianate

2)Inhibitry:-

Ligand gated ion chanel--GABAa,Glycine

G-protein--GABAb


NAA @ 08141811271: 18-September-2010

PGE1:Misprostol(Peptic ulcer),Oral cotntrceptive n Condoms testing-INDIA

PHARMACOPEIAL LAB- GHAZIABAD,


NAA @ 08141811271: 18-September-2010

Specific tests:-

Raymond's- Cardiac gly;Klunge's- Isobarbaloin(Aloe);Shinoda- Flavanoid;Fiehe's-

Honey;Matchstick- Catechu;Van urk's- Ergot,

habari: 18-September-2010

hey, visit our academys website www.niperacademy.com , ull find all the

Rankers,Faculty,Academy Adresses,coaching schedule,Registration form etc


NAA @ 08141811271: 17-September-2010

NMR UNITS:field strength-tesla,gyromgneticratio-rad/tesla,chemicalshift-ppm,couplingconst-

hertz ,Pluronics=polyoxyethylene+propylene



2010

chemical basic nucleus found in the anti leproti drug clofazimine is IMINO-

PHENAZINE.ramana



2010

physostigmine a anticholinestarase agent is also called eserine vch vl oxidised 2 a red

compnd RUBESERINE in air n light . Ramana


NAA @ 08141811271: 16-September-

2010

D&C ACT-1940

NARCOTC&PSYCOTRPIC -1985




PHARMCY ACT-1948

ACT.Oral cotntrceptive n Condoms testing-INDIA PHARMACOPEIAL LAB-

GHAZIABAD


NAA @ 08141811271: 16-September-

2010

we the ownrs of dis channel wnt 2 guide u thru our communities,so join in our communities

NIPER ACADEMY HYDERABAD and NIPER in ORKUT


NAA @ 08141811271: 15-September-

2010

Soft gels commercial names

Agarose sepharose, Dextran sephadex, Polyacrylamide biogel


NAA @ 08141811271: 15-September-

2010

commercial varieties of opium

chinese flat, turkish conical, indian cubical, persian granular. Remember exactly


NAA @ 08141811271: 15-September-2010

Polyurethane cloth liner to remove dust. Erveka KEA used for dedusting n polishing hard gelatin

capsule.


NAA @ 08141811271: 14-September-2010

Chlorogenic acid ,Ipecacaunhic acid,catechins are Pseudotanins

Florentine receivr used to detrmin density of liquids

Nicotinic acid+diethyl amide-->Nikethamide


Ramana: 14-September-2010

Hai GATE aspirants. Rwlfia gvs violet clr vd Vanillin n megent red vd HN03. Ramana.


NAA @ 08141811271: 13-September-

2010

Zidovudine shows bone marrow toxicity,COX 1 is constitutive and COX 2 is

inductive,Latanoprost eye drops used in Glaucoma.


NAA @ 08141811271: 13-September-

2010

Huntington's disease is due to over activity of dopaminergic activity and deficiency of

GABA,Morphine belongs to phenanthrene class of alkaloids


NAA @ 08141811271: 13-September-

2010




Clioquinol is the drug used in Alzhemier's disease,Dronabinol apetite stimulant used during

AIDS,Satilex is a cannabinoid usd in neuropathic pain


NAA @ 08141811271: 12-September-

2010

Which tablet does not require disintegrant

i)SUBLINGUAL ii)effervescent iii)Buccal iv) dissolution tab


NAA @ 08141811271: 12-September-

2010

Orlistat and sibutiramine are the two anti obesity class drugs.Dry cough is seen with

ACEI,Gamma picoline is starting material for isoniazid synt


NAA @ 08141811271: 12-September-

2010

Dover's powder is mixture of Ipecac & opium used as a Expectorant.

Zilutone is a 5-Lipoxygenase Inhibtor ,antifungal prep- whitfield's ointment.


NAA @ 08141811271: 11-September-2010

Phenytoin adr pheripheral neuritis,


pyridoxin is used for both drugs...

Also reqired as co factor for enzymes


NAA @ 08141811271: 11-September-2010

hey last msg related to ICH zone, temperature,humidity. dnt confuse. its important

NAA @ 08141811271: 11-September-2010

0@10-15

1@20-25,

2@20-300,

3@300-3000

4@Post marketing surveiliance

ICH zones

l 21?c 45

ll 25?c 60

lll 30?c 35

lV 30?c 70


NAA @ 08141811271: 10-September-2010

JNTU students who r in 4th yr, dont waste time on seminars, it gives nothing now. Concentrate

on coaching classes


NAA @ 08141811271: 10-September-

2010




hi, keep listening to our faculty lectures n write d notes exactly Wt they taught.. For MC

PRAVEEN sir notes is enough.


NAA @ 08141811271: 10-September-

2010

Redman syndrome Vancomycin,Aspirin Reyes syndrome, Bad dream syndrome

PropranololGattelman synd loop diuretics


NAA @ 08141811271: 09-September-

2010

Para nitro phenol + hexamine = CHLORAMPHENICOL

Anthracyclins obtained from Streptococcus peucitus


NAA @ 08141811271: 09-September-

2010

hey dnt delete any academys msgs from ur cell phone, just read those when u r travelling or

when u r free..... do reading them regularly

SMEET@08141811271: Clenbutrol-anabolic drg usd illicitly by athletes 2 improve

performance

4 chest infection in asthma-clarithromycin used.


MOHIT@NIPER@08141811271: 2 08141811271

Parth More: lotaustralin-isoleucin

Imp characters:

Nutmeg-aril

stropanthus-arista(awn)

cardamon-arilode

colchicum-strophiole

castor-caruncl


MOHIT@NIPER@08141811271: 2 08141811271

Parth More(GPAT 1st): squill,manna,psyllium-cntain trisaccharide.

Glycoside&Aglycone:

http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=150http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=150http://labs.google.co.in/smschannels/channel/MITHRA_ACADEMY?tab=posts&post_start=150http://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din



Prunasin-phenylalanine

linamarin-valine

lotaustralin-is


MOHIT@NIPER@08141811271: 3 08141811271

NAA @ 08141811271ansh@08141811271: correct strctr of Penicillin gvn by:

a) fleming

b) ronald hare

c) robert robinson

d) marc

Ans is C)

ask ur frnds to join ds.


MOHIT@NIPER@08141811271: 3 08141811271

Parth More(GPAT,1st): Clofazimine is dye dt interfere with DNA templete function.

Zidovudine+stavudine not preferd in HAART treatment.


MOHIT@NIPER@08141811271: 3 08141811271

Parth More(GPAT,1st): Drug of choice:for

Onchoerciasis-Ivermectin

meningitis-benzyl penicillin

dermatophytosis-Zn salt of undecylanic acid


MOHIT@NIPER@08141811271: 4 08141811271

Parth More(GPAT,1st): alkaloids 4m tyrosine-

morphine,codeine,thebain,papaverin,colchicine etc

Cosmid=plasmid+bacteriophage lamda,cntain cos si


MOHIT@NIPER@08141811271: 4 08141811271

HITESH (NIPER,4TH): WIthdrawn 4m market due to:

Rofecoxib,Fenfluramine- coz cardiac prblms

cerivastatin-rhabidomylosis

Rosiglitazone-heart attac

http://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din




MOHIT@NIPER@08141811271: 4 08141811271

NAA @ 08141811271ansh@08141811271: In GC, detector & its sensitivity:

TCD-10^-6 to 10^-8 gm

FPD-10^-10

FID-10^-11

Alkali FID-10^-12

PID-10^-12

ECD-10^-13


MOHIT@NIPER@08141811271: 5 08141811271

$ANJAY: Wurster process=Air suspension.

Reterobulbular(Optic) neuritis-S/E of Ethambutol,Male fern, glucocorticoids,amiodarone.

u cn also post.

Parth More(GPAT,1st): alkaloids 4m tyrosine-

morphine,codeine,thebain,papaverin,colchicine etc

Cosmid=plasmid+bacteriophage lamda,cntain cos si


MOHIT@NIPER@08141811271: 4 08141811271

HITESH (NIPER,4TH): WIthdrawn 4m market due to:

Rofecoxib,Fenfluramine- coz cardiac prblms

cerivastatin-rhabidomylosis

Rosiglitazone-heart attac


MOHIT@NIPER@08141811271: 4 08141811271

NAA @ 08141811271ansh@08141811271: In GC, detector & its sensitivity:

TCD-10^-6 to 10^-8 gm

FPD-10^-10

FID-10^-11

Alkali FID-10^-12

PID-10^-12

ECD-10^-13


MOHIT@NIPER@08141811271: 5 08141811271

$ANJAY: Wurster process=Air suspension.

http://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?cr=in&continue=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Din&prev=/smschannels/browse%3Fcat%3DAll%26sort%3D2%26ctab%3DMy%26select%3Dstatus%253AAll%26cr%3Dinhttp://labs.google.co.in/smschannels/channel/NIPER-THRUST?tab=posts&post_start=10http://labs.google.co.in/smschannels/channel/NIPER-THRUST?tab=posts&post_start=10http://labs.google.co.in/smschannels/channel/NIPER-THRUST?tab=posts&post_start=10



Reterobulbular(Optic) neuritis-S/E of Ethambutol,Male fern, glucocorticoids,amiodarone.

u cn also post.


MOHIT@NIPER@08141811271: 5 08141811271

SMEET@08141811271: Teclifenasine-most recent drug to treat dementia by action on M1

receptor.

Darifenasine is d selective M3 receptor antgonist..


MOHIT@NIPER@08141811271: 5 08141811271

Parth More: Anisidone- platelet aggregation inhibitor gvs orange urine due to its metabolic

pdt.

Adulterant of Asafoetida- Lime stone..


MOHIT@NIPER@08141811271: 6 08141811271

Parth More@GPAT 1st: most Imp 4 NIPER:

Coupling cnstnt of geminl,cis,trans,ortho,meta,para,anti,gouche strctr,t-butyl cyclohexane

do it 4m Pavia.


MOHIT@NIPER@08141811271: 6 08141811271

Parth More: Brij is Polyethylene lauryl ether..

Myrj is polyoxyethylene monotearate..

streptomycin + vecuronium= synergistic effect..


MOHIT@NIPER@08141811271: 6 08141811271

MOHIT@NIPER@08141811271: Wish u best luck in all ur future endeavour 4m ENZiME

NIPER-THRUST team.

HAPPY NEW YR.

Keep smiling n lets make other 2 Smile.


MOHIT@NIPER@08141811271: 7 08141811271

SMEET@08141811271: flocc. susp. folow plastic/pseudoplastic flow..

Deflocc. susp.-dilatant flow.

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Trypsin enz break linkage bw lysin-arginine..

NAA @ 08141811271ansh@08141811271: Best stability is achieved by complexation with:

A. Cyclodextrin

B. Na benzoate

C. Sulfobutyl ether beta CD

D. Tween

Ans is C.


MOHIT@NIPER@08141811271: 7 08141811271

Parth More: hi frns,i m r8 nw in NIPER(Mohali) ceutics.

Which bacteria most difficult 2 remove 4m water?

Pseudomonas.

Ask ur frns 2 join ds.


MOHIT@NIPER@08141811271: 8 08141811271

SMEET@08141811271: PLUG FLOW is disadv of Cup&Bob viscometer

Best herbal antidepresant is Hyperforin

DNA topoisomerase-I inhibitor: Irino&Topoteca


MOHIT@NIPER@08141811271: 8 08141811271

NAA @ 08141811271ansh@08141811271: Radio mirchi has radio frequency in fresnel unit

is equal to:

A.98.3*10^-5

B.98.3*10^-4

C.9.83*10^-5

D.0.983*10^-6

Ans on tomo..


MOHIT@NIPER@08141811271: 8 08141811271

MOHIT@NIPER@08141811271: DNA Gyrase or Topoisomerase-II inhibitors:

Anilinoacridine,Amsacrine,Etoposide,Dactinomycin,Doxorubicin& All Quinolones..


MOHIT@NIPER@08141811271: 9 08141811271

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NAA @ 08141811271ANSH@08141811271: O/W/O emulsion is also called as:

A.Double emulsion

B.Multiple emulsion

C.Both A & B

D.simple emulsion

Ans is C.

have a nice da


MOHIT@NIPER@08141811271: 9 08141811271

NAA @ 08141811271ANSH@08141811271: Paras Pharmaceuticals is taken over by:

A.Reckitt Benckiser

B.Pfizer

C.Abott

D.Ranbaxy

Ans is A...

Ask ur frnds 2 join ds chann


MOHIT@NIPER@08141811271: 9 08141811271

MEGHAL@MSU: Which of d following drug hv 100% oral bioavaibility?

A.Ciprofloxacin

B.letrozole

C.levofloxacin

D.Both B & C.

Ans is D.

gd morni


MOHIT@NIPER@08141811271: 11 08141811271

SMEET@08141811271: western blotting test-HIV infection

Southern blotting-DNA testing

Northern blotting-mRNA transmition

Success Never Ends..


MOHIT@NIPER@08141811271: 11 08141811271

SMEET@08141811271: 100 proof spirit=57.1% alcohol

Sterilization with gamma rays is k/a cold sterilization..

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5.4%dextrose,2%boric acid is isotonic.


NAA @ 08141811271ansh@08141811271: Drying instrument used for Gelatin is:

A.Spray

B.Drum

C.Tray

D.Freeze

Ans is B....

Antidote in opium poisoning is belladona.


MOHIT@NIPER@08141811271: 12 08141811271

NAA @ 08141811271ansh@08141811271: Quinolone crosses BBB:

A.Norfloxacin

B.Ofloxacin

C.Sparfloxacin

D.Roxefloxacin

Ans is B

phototoxicity seen with lome&Sparflox


MOHIT@NIPER@08141811271: 12 08141811271

NAA @ 08141811271ansh@08141811271: Ethosomes-soft, malleable vesicle made up of

phospholipids,Ethanol,water.

Used as novel carrier 4 enhanced delivery to/thru skin.


MOHIT@NIPER@08141811271: 12 08141811271

NAA @ 08141811271ansh@08141811271: Drug usd in prophylaxis of Asthma?

A.Cyproheptadine

B.Chromoline

C.Mepyramine

D.Zirtex

Ans: B-Chromoline

Ask ur more frns 2 joi


MOHIT@NIPER@08141811271: 13 08141811271

$anjay@08141811271: Penicilin G:benzyl penicilin

X: P-OH penicilin

K: n-heptenyl




V: phenoxymethyl

F: 2-pentenyl

Alternative 2 DOP test is liq paraf


MOHIT@NIPER@08141811271: 13 08141811271

$: As sm ppl didnt get ysrtdys msg.

Jst go thru ds 2 download paper:

http://hotfile.com/dl/91367406/9a99d46/GPAT_1ST_PAPER.zip.html

n gv ur fdbc


MOHIT@NIPER@08141811271: 13 08141811271

$: Solid content in Parenteral:bw 0.5 to 5 % for I.M. & S.C. bt p. size NMT 5 micron.bt

some antibiotic prep hv solid content upto 30%..


MOHIT@NIPER@08141811271: 24-December-2010

$: Go thru ds:

http://hotfile.com/dl/91367406/9a99d46/GPAT_1ST_PAPER.zip.html

n download paper 4 gpat.

small initiative to help u,hope u like it



$: Combination of circular birefringence&circular dichroism is called cotton effect.

Octant rule usd 2 identify d sign&magnitude of cotton effect.



MOHIT@NIPER@08141811271: Patented technologies 4 fast dissolving pdts:

Zydis,

Orasolv,

Durasolv,

Flashdose,

Wowtab,

Flashtab,

Oraquick.

already askd in

DHAVAL@NIPER: Neutral thioaliphatic amino acid in protein is

A)Cystiene




B)Leucine

C)Valine

D)Glycine

Ans is (A)-Cystiene..

Ask ur frnds to jo


MOHIT@NIPER@08141811271:

23-December-

2010

DHAVAL@NIPER: 5-HT antagonist has antihypertensive property is:

a)Methysergide

b)Cyproheptadine

c)Ketanserine

d)Ondansetron

ANS IS (C)-KETANSE



MOHIT@NIPER@08141811271: HEPA filter integrity testing done on:

a) Daily

b) Monthly

c) Yearly

d) Every 6 months

Ans is (C)-yearly..



MOHIT@NIPER@08141811271: In order 2 prepare NDDS 4m release erythrocyte,4 d

purpose of loading d drug in erytyhrocytes,are placed in:

HYPOTONIC SOLUTION..



MOHIT@NIPER@08141811271: Method uses HIGH VOLT. CURRENT 2 improve drug

delivery thru skin:

ans is electroporation..

mind well...



MOHIT@NIPER@08141811271: Method uses HIGH VOLT. CURRENT 2 improve drug

delivery thru skin:




a)Sonophoresis

b)Iontophoresis

c)Magnetoph.

d)Electroporation

A



MOHIT@NIPER@08141811271: 1 more gd news 4 u is dt my frnd,PARTH MORE,GPAT-

2010 all india 1st ranker is going to post in our channel frm 24th dec..so dnt panic.



MOHIT@NIPER@08141811271: Eudrophonium is used in ameliorative test of Myasthenia

gravis.

Straubb reaction in rats is shown by morphine.



MOHIT@NIPER@08141811271: Reference std.

FOR MASS SPECT.:PERFLUROKEROSENE

FOR IR : POLYSTYRENE FILM

FOR NMR: TMS (FOR NON AQEOUS ONLY as it is water insol).

MOHIT@NIPER@08141811271: Reference std.

FOR MASS SPECT.:PERFLUROKEROSENE

FOR IR : POLYSTYRENE FILM

FOR NMR: TMS (FOR NON AQEOUS ONLY as it is water insol).



19-December-

2010

KRUNAL@MSU: LAL test used 4 detection & quantification of endotoxins(only Gm-

ve),semiquantitative test&reslt depend on clotting/coagulation of LAL.



KRUNAL@MSU: Water attack test is performd on TYPE-II glass.

In remaining type of glass, Powder attck test is performed...

ask ur frnds 2 join ds.






MOHIT@NIPER@08141811271: NIPER QUEST:

Size reduction of sub. 2 extremely fine state by rubbing on slab with help of insoluble liquid

is called LEVIGATION.



MOHIT@NIPER@08141811271: Polysorbate20 inactivate paraben,

Quat ammonium inactivate azolactin,

Phenyl Hg nitrate by sulfide residue of rubber.

(From Remingt



MOHIT@NIPER@08141811271: Primary std for Karl Fischer titration is Na tartrate

dihydrate.

Kjeldahl method used for Nitrogen estimation.



MOHIT@NIPER@08141811271: Possible contaminant virus in MEASLE VACCINE-

Avian leucosis.

In frz dried BCG VACCINE-Polyoxy ethylene ether added to avoid clump.



MOHIT@NIPER@08141811271: Suxamethonium& Halothane coz malignant hyperthermia

due to mutation of ryanodine(R),excessive ca release.treatment is by Dantrolene.



MOHIT@NIPER: Brand name ----Uses

Idropostal -water sol suppository

Witepsol555 -vaginal suppo

WitepsolE75 -eutectic mixture.

check out lachman..






MOHIT@NIPER: PADDLE TYPE APPARATUS - TYPE 1 AS PER I.P., B.P.&TYPE 2

AS PER USP.

BASKET TYPE APPARATUS- TYPE 2 AS PER I.P., B.P.&TYPE 1 AS PER USP.

MOHIT@NIPER@08141811271: Suxamethonium& Halothane coz malignant hyperthermia

due to mutation of ryanodine(R),excessive ca release.treatment is by Dantrolene.



17-December-

2010

MOHIT@NIPER: Brand name ----Uses

Idropostal -water sol suppository

Witepsol555 -vaginal suppo

WitepsolE75 -eutectic mixture.

check out lachman..



MOHIT@NIPER: PADDLE TYPE APPARATUS - TYPE 1 AS PER I.P., B.P.&TYPE 2

AS PER USP.

BASKET TYPE APPARATUS- TYPE 2 AS PER I.P., B.P.&TYPE 1 AS PER USP.



MOHIT@NIPER: Adv. of solid dispersion:

reduction p. size,improved wettability,higher porosity,Drug converts in amorphous stage.

do PEGylation..its imp



S: Approaches to enhance solubility:

Pseudopolymorphs,Complexation/solubilization,Drug dispersion in carriers,Prodrugs,Salts

form of drug...



S: Approaches (p. size modification) to enhance solubility:

Nanosusp.,Micronization,Modifications of crystal habit,Polymorphs,cont..



MOHIT@NIPER@08141811271: Vancomycin causes red man syndrome.




Chloramphenicol causes Gray baby syndrome.

Amiodarone-gray man syndrome.

Aspirin-Reye's synd..



MOHIT@NIPER@08141811271: Pluronics are combination of polyoxyethylene and

propylene.

Cabot is glidant.

Dover's powder:mixture of Ipecac&opium-as Expectorant



MOHIT@NIPER@08141811271: hi frns,

4 mre gud posts & 2 acquire mre knowledge join my othr co-group.

Send

ON PHARMAKNOWLEDGE

& snd it to 09870807070.



MOHIT@NIPER@08141811271: Ask your frnds to join ds channel..

"ON NIPER-THRUST" to +919870807070.

Ask ur frnds to enjoy fantastic posting on ds channel.

MOHIT@NIPER@08141811271: Pluronics are combination of polyoxyethylene and

propylene.

Cabot is glidant.

Dover's powder:mixture of Ipecac&opium-as Expectorant



13-December-

2010

MOHIT@NIPER@08141811271: hi frns,

4 mre gud posts & 2 acquire mre knowledge join my othr co-group.

Send

ON PHARMAKNOWLEDGE

& snd it to 09870807070.



MOHIT@NIPER@08141811271: Ask your frnds to join ds channel..

"ON NIPER-THRUST" to +919870807070.




Ask ur frnds to enjoy fantastic posting on ds channel.



MOHIT@NIPER@08141811271: Water soluble antioxidants:

Ascorbic acid, Acetyl cystene, Na metabisulfite, Na thiosulfate, Cysteine, Thioglycolic acid,

Na sulfite.



MOHIT@NIPER@08141811271: Oil soluble Antioxidants:

BHA, BHT, Hydroquinone, Propyl gallate, Ascorbyl palmitate, Tocoperols.

Many times asked in GATE & NIPER.



MOHIT@NIPER: Code of Aminoacid:

F for phenyl alanin

W-tryptophan

N-aspargin

Q-glutamin

Y-tyrosin

D-aspartic acid

E-glutamic acid

K-lysin

R-argi



MOHIT@NIPER@08141811271: Gold No. of following:

gelatin-0.01-0.05

albumin-0.1

acacia-0.1-0.2

tragacanth-2



MOHIT@NIPER@08141811271: Hair growth caused by

Minoxidil,Diazoxide,Valproate,Finasteride,Dutasteride.

Cough produced by ACE inhibitor,Halofentrene,Na stilbo






MOHIT@NIPER@08141811271: IR solvents:-CHCl3,CS2,CCl4 (non-aq. solvents).

As Ref. Std in IR- Polystyrene film is used.

Nujol is highly purified liq.paraffin.



MOHIT@NIPER@08141811271: ACE inhibitor's specific side effect is oligohydraminos

and cough.

toxic metabolite of PCM is N-acetyl-para-benzoquinoneimine (NAPQI)

MOHIT@NIPER@08141811271: ACE inhibitor's specific side effect is oligohydraminos

and cough.

toxic metabolite of PCM is N-acetyl-para-benzoquinoneimine (NAPQI)



09-

December-

2010

MOHIT@NIPER@08141811271: St. Johnson syndrome is s/e of-

itraconazole,fluconazole,Amprenavir,nevirapine,carbamazepine,phenylbutazone,sulfonamid

e,Lamotrigine, T



Alopecia(hair loss) caused by:

phenytoin,flucytocin,doxorubicin,etoposide,acenocoumarol,ethyl biscoumacetate.

JOIN UR FRNDS TO NIPER-THRUST..TH



MOHIT@NIPER@08141811271:-

Protective colloids:-Na CMC, PEG-4000, Acacia, Lecithin.

Parenteral suspension:-solids NMT 0.5-5%.

Microemulsion p.size NMT 120nm.



MOHIT@NIPER@08141811271:-




Metronidazole, Quinine, Atorvaquone, Mefloquine not given o pregnant woman.

while Chloroquine can be given to pregnant woman....



Disulfiram like action produced by cefoperazone, mebendazole, metronidazole,

procarbazine, chlorpropamide, nitrofurantoin....

enjoy pharmacology..



crystal urea caused by thiabendazole, ciprofloxacin, methanamine, sulphonamide,

methotrexate.

Add ur frnds to get max benefit of ds channel..



Pellet size ranges from 0.5-1.5 mm.

MCC is d most common diluent to prepare pellets.

extrusion spheronization is most common tech to prepar pelle



OSELTAMIVIR and ZANAMAVIR BOTH CAN BE USED IN SWINE FLUE

TREATMENT.....

Dipivefrin (prodrug of epinephrin) converted By ESTERASE to epinephrine and "PIVALIC

ACD"

It is use in open angle glaucoma. always with u.


NAA @ 08141811271: 06:07

Fancony syndro is due to degraded tetracycln like

1 anhydro tetra.cy(t.c)

2 epitetra cycl.

3 epi anhydro tc.produced during long storage.


NAA @ 08141811271: 08141811271

Amprenavir- s j syndrome

kidney stone _ indinavir.

Efevirenz- 99% protein bound so less plasma level.

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Ritonavir- p450 more inhibitor.


NAA @ 08141811271: 08141811271

Cefoperazone-disulfiram like rxn

cefazolin-surgical prophylaxis

Documents

NIPER ASPIRANTS ACADEMY AHMEDABADpharmacol.weebly.com/uploads/3/7/8/8/3788687/gpat_sms-1.pdfsree: Biosynthesis of Alkaloids Atropine,NIcotine-Ornithine Coniine,Lycopodine,Piperidine