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Novocastra HD - GynepathologyHighly Definitive Antibodies
Trust the HD Difference – Highly Definitive Antibodies for Diagnostic Confidence• Independently benchmarked against leading equivalents by external QA*
• Establishing a new quality standard in IHC; simplifying antibody selection
*Independent analysis commissioned by Leica Biosystems and conducted by NordiQC according to the manufacturers’ instructions for use and on the corresponding staining platform.
BOND 7 mL PA0270
BOND 30 mL PA0131
Liquid 1 mL NCL-L-CD10-270
CD10 Clone 56C6
BOND 7 mL PA0007
Liquid 1 mL NCL-L-CD117-032
Human Gastrointestinal Stromal TumorIntense membrane staining of tumor cells.
CD117 (c-kit Oncoprotein)
Clone EP10 Cytokeratin 5 Clone
XM26
BOND 7 mL PA0468
Liquid 0.5 mL NCL-L-CK5
Liquid 1 mL NCL-L-CK5
Cytokeratin 7 Clone RN7
BOND 7 mL PA0942
BOND 30 mL PA0138
Liquid 1 mL NCL-L-CK7-560
Human Lymphoblastic LymphomaIntense membrane staining of neoplastic lymphoid cells.
Ductal Carcinoma In SituIntense staining of myoepithelial cells.
Epithelial Myoepithelial CarcinomaThe luminal cells show intense staining with CK7 in comparison with the weaker staining of the abluminal (myoepithelial) cells.
Human Colonic Mucinous AdenocarcinomaCytoplasmic and membrane staining of absorbative intestinal epithelial cells and malignant tumor cells.
Carcinoembryoinic Antigen (CD66e)
Clone COL-1
BOND 7 mL PA0848 NEW
Liquid 1 mL NCL-L-CEA-609 NEW
Human Adenocarcinoma of EndometriumCytoplasmic and extracellular staining of malignant glandular endometrial cells.
CA125 Clone OV185:1
BOND 7 mL PA0539 NEW
Liquid 1 mL NCL-L-CA125 NEW
Novocastra HD - Gynepathology
Estrogen Receptor Clone 6F11
BOND 7 mL PA0151
BOND 30 mL PA0009
Liquid 1 mL NCL-L-ER-6F11
Liquid 2mL NCL-L-ER-6F11 N/A USA
Ki67 Clone MM1
BOND 7 mL PA0118
BOND 30 mL PA0410
Liquid 1 mL NCL-L-Ki67-MM1
Human Ductal Carcinoma Intense staining of a proportion of breast cancer cells.
Human Squamous Cell CarcinomaNuclear staining in a high proportion of malignant cells.
Mismatch Repair Protein (MLH1)
Clone ES05
BOND 7 mL PA0610
Liquid 1 mL NCL-L-MLH1
Invasive Ductal Carcinoma High ExpressorIntense nuclear staining in nearly 100% of tumor cells.
Human TonsilNuclear staining in the majority of proliferating lymphocytes.
Liquid 1 mL NCL-L-MSH2
Mismatch Repair Protein (MSH2)
Clone 25D12
BOND 7 mL PA0057
Liquid 0.5 mL NCL-L-p53-D07
Liquid 1 mL NCL-L-p53-D07
p53 Clone DO-7
Human Ductal Carcinoma Intense nuclear staining of tumor cells.
Cytokeratin 20 Clone Ks20.8
BOND 7 mL PA0022
BOND 30 mL PA0037
Liquid 0.5 mL NCL-L-CK20
Liquid 1 mL NCL-L-CK20
Human ColonIntense staining in the crypts.
Human SeminomaStrong membrane and cytoplasmic staining of malignant cells.
BOND 7 mL PA0161
Placental Alkaline Phosphatase (PLAP)
Clone 8A9
BOND 7 mL PA0312
Liquid 1 mL NCL-L-PGR-312
Liquid 2mL NCL-L-PGR-312/2 N/A USA
Progesterone Receptor
Clone 16
BOND 7 mL PA0640
Liquid 0.5 mL NCL-L-VIM-V9
Liquid 1 mL NCL-L-VIM-V9
BOND 7 mL PA0562
Liquid 1 mL NCL-L-WT1-562
Vimentin Clone V9 Wilms’ Tumor Clone
WT49
Breast CarcinomaNuclear staining in a proportion of tumor cells.
Spindle Cell CarcinomaA spindle cell carcinoma showing intense vimentin staining.
Human Kidney, Wilms’ TumorNuclear staining of invasive tumor cells.
BOND 7 mL PA0943
Liquid 1 mL NCL-L-SMA
Human LeiomyosarcomaCytoplasmic staining of smooth muscle of vascular elements and of tumor cells.
Smooth Muscle Actin, Alpha (SMA)
Clone αsm-1
Human Testis, SeminomaIntense staining of pluripotent tumor cells.
BOND 7 mL PA0193 NEW
Liquid 1 mL NCL-L-OCT3/4
Oct-3/4 Clone N1NK
LeicaBiosystems.com
Novocastra HDHighly Definitive Antibodies
Benefits of BOND Ready-to-Use antibodies
✓ Optimized for staining performance on BOND
✓ Validated antibody concentrations
✓ Ease of use: just plug and play
✓ Increase standardization through automation
✓ Eliminate variability in antibody preparation
Benefits of concentrated liquid antibodies
✓ Flexibility of use on various platforms1
✓ Adaptable to a variety of detection systems1
✓ Adjustable concentration to suit user’s tissue1
✓ Economical option that retains confidence in clone selection
1. The performance of antibodies should be validated when used with automated platforms or manual staining systems other than stated on Instructions for Use.
Improve workflow efficiency and streamline validation.
95.13346 Rev C · 03/2016 · Copyright©2016 Leica Biosystems Newcastle Ltd. All rights reserved. LEICA and the Leica Logo are registered trademarks of Leica Microsystems IR GmbH. Novocastra and BOND are trademarks of Leica Biosystems and its affiliates. Other logos, product and/or company names might be trademarks of their respective owners. The EP clones have been created by Epitomics Inc., using Epitomics’ proprietary rabbit monoclonal antibody technology covered under Patent No.’s 5, 675, 063 and 7, 402, 409.
Independently Evaluated* Specifically SelectedEach antibody in the range has been independently evaluated* by external QA, NordiQC, in comparison with equivalent products from other vendors. The range represents the highest performing antibodies that Leica Biosystems offers for the most commonly performed IHC tests.
*Independent analysis commissioned by Leica Biosystems and conducted by NordiQC according to the manufacturers’ instructions for use and on the corresponding staining platform.