Nuclear Physics in MedicineChapter: Medical Imaging

NuPECC liaisonsAlexander Murphy and Faiçal Azaiez

ConvenersJose Manuel Udias and David Brasse

Table of Content

First part: State of the art1 - PET/SPECT/MRI2 - Preclinical instrumentation

Second part: prospects/challenges3 - New challenges in multimodality imaging4 - New challenges in detector design5 - Software: reconstruction and simulation6 - Photon counting: towards spectral CT7 - Interface between medical imaging and hadrontherapy8 - Interface between medical imaging and mass spectrometry

« State-of-the-art » Part

Mainly to introduce the chapter at the clinical level

Positron Emission TomographyStand-alone,Multimodality PET/CT, PET/MR

Single Photon Emission Computed Tomography

PET/SPECT (Peter Dendooven )

Preclinical Instrumentation (Alberto Del Guerra)

Presentation of the different technologiesPET/SPECT/CTMRI and PET/MR (to be written yet)

Multimodality approaches

« Prospects/Challenges » Part

New Challenges in Multimodality Imaging (Ian Lazarus)

PET and SPECT combined to MRITake advantage of TOF PET in MRI

New Challenges in Detector Design (Piergiorgio Cerello, Peter Thirolf)

Detector module componentscintillators, photodetector, front-end electronics

One example of new concept challenging the detector design 3 gammas imaging (link to radionuclide chapter)

Software: Reconstruction and Simulation(M. Rafecas, I. Torres-Espallardo, P. Solevi and J. F. Oliver )

Image Reconstruction (system matrix, TOF…)Acceleration procedure (algorithm, hardware)QuantificationSimulation

Photon Counting: Towards Spectral CT (Christian Morel )

Detector designIntroduction to spectral X-rayProspects: detector and application (K-edge imaging…)

Interface with Hadrontherapy (M. Priegnitz, W. Enghardt, F. Fiedler )

Imaging systems for quality controlPositron Emission TomographyPrompt gamma rayCharged particle ImagingProton CT

Interface with Mass Spectrometry (Christoph Scheidenberger )

Introduction to Mass spectrometryTechnics for biomedical applicationsSome applications

More editing work has to be done to improve the homogeneity of the chapter

About 20,000 words of content at present, too short / long?

Some remaining questions:

-Font type and size ?-Format of the references in the text ?-Should we put the list of references after each section or at the end of the chapter ?-Is there a limited number of references ?

-Should we include the mass spectrometry in our chapter or is an interface chapter by itself ?-Should we introduce 3 gammas imaging as a separate section like “interface to radionuclide chapter ?…