NURG- RheumatologyNURG- RheumatologyBasic Classification of the Basic Classification of the Rheumatic DiseasesRheumatic Diseases

• Doc.MUDr.Marie Valešová, CScDoc.MUDr.Marie Valešová, CSc

• I.Interní klinika FNKV a 3.LF UKI.Interní klinika FNKV a 3.LF UK

RheumatologyRheumatology

• Rheumatological disorders are one of Rheumatological disorders are one of the most widespred groups of the most widespred groups of diseases in the world.diseases in the world.

• Musculoskeletal system - joints, Musculoskeletal system - joints, bones, spine,bones, spine,

• Any organ system may be affected, Any organ system may be affected,

Basic Classification of the Basic Classification of the Rheumatic DiseasesRheumatic Diseases

1.1. A. Inflammatory Rheumatic DiseasesA. Inflammatory Rheumatic Diseases2.2. B. Degenerative Joint DiseaseB. Degenerative Joint Disease3.3. C. Metabolic and Endocrine Diseases C. Metabolic and Endocrine Diseases

associated with rheumatic statesassociated with rheumatic states4.4. D. Extraarticular disordersD. Extraarticular disorders5.5. E. Rheumatic syndrome associated with E. Rheumatic syndrome associated with

infectious agentsinfectious agents6.6. F. Bone and cartilage disordersF. Bone and cartilage disorders7.7. G. OthersG. Others

B. Degenerative Joint DiseaseB. Degenerative Joint Disease

• OsteoarthritisOsteoarthritis

jointsjoints

spinespine

1.1. RegionalRegional

2.2. GeneralizedGeneralized

A. Inflammatory Rheumatic A. Inflammatory Rheumatic DiseasesDiseases

1.1. Diffuse connective tissue diseasesDiffuse connective tissue diseases

2.2. Arthritis associated with spondylitisArthritis associated with spondylitis

(Spondylarthritis)(Spondylarthritis)

Diffuse connective tissue Diffuse connective tissue diseasesdiseases

1.1. Rheumatoid arthritis (RA)Rheumatoid arthritis (RA)

2.2. Systemic lupus erythematosus(SLE)Systemic lupus erythematosus(SLE)

3.3. Systemic sclerosis (SS)Systemic sclerosis (SS)

4.4. Polymyositis (PM)-Polymyositis (PM)-Dermatomyositis(DM)Dermatomyositis(DM)

5.5. Sjőgren´s syndromeSjőgren´s syndrome

6.6. VasculitidesVasculitides

Arthritis associated with Arthritis associated with spondylitisspondylitis (Spondylarthritis (Spondylarthritis))

1.1. Ankylosing Spondylitis (AS)Ankylosing Spondylitis (AS)

2.2. Psoriatic Arthritis (PsA)Psoriatic Arthritis (PsA)

3.3. Reactive Arthritis (ReA)Reactive Arthritis (ReA)

4.4. Enteropatic arthritis –A.associated Enteropatic arthritis –A.associated with inflammatory bowel Diseaseswith inflammatory bowel Diseases

C. Metabolic and Endocrine C. Metabolic and Endocrine Diseases associated with Diseases associated with rheumatic statesrheumatic states1.1. Crystal associated conditions - gout Crystal associated conditions - gout

2.2. Other biochemical abnormalitiesOther biochemical abnormalities HemofiliaHemofilia AmyloidosisAmyloidosis3. 3. Endocrine Endocrine diseasesdiseases Diabetes mellitusDiabetes mellitus AcromegalyAcromegaly Hyper and hypothyreodism Hyper and hypothyreodism

D. Extraarticular disordersD. Extraarticular disorders

1.1. Localized Localized a) a) juxtaarticular lesionsjuxtaarticular lesions-bursitis-bursitis,, tendinitis, tendon lession, tendinitis, tendon lession, enthesopathyenthesopathy

b) b) intervertebral disc disordersintervertebral disc disorders c) Low back pain, idiopathicc) Low back pain, idiopathic2. Generalized 2. Generalized Fibromyalgia Fibromyalgia

E. Rheumatic syndrome E. Rheumatic syndrome associated with infectious associated with infectious agentsagents• Direct- infectiousDirect- infectious

1.Bakterial – gonoccocal,TBC1.Bakterial – gonoccocal,TBC

Lyme diseaseeLyme diseasee

2.Viral2.Viral

3.Fungal3.Fungal

4.Parasitic4.Parasitic

• Reactive Reactive – Acute revmatic fever, – Acute revmatic fever,

postdysentericpostdysenteric

F. Bone and cartilage disordersF. Bone and cartilage disorders

• OsteoporosisOsteoporosis

• OsteomalatiaOsteomalatia

• Hypertrophic artropathyHypertrophic artropathy

F.OthersF.Others

• Neoplasm and paraneoplastic Neoplasm and paraneoplastic syndromasyndroma

• Avascular necrosisAvascular necrosis

• Neurovascular disordersNeurovascular disorders

1.Compression syndromes1.Compression syndromes

2.Charcot Joint2.Charcot Joint

• SarcoidosisSarcoidosis