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Oct 31, 2008

Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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Page 1: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

Oct 31, 2008

Page 2: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

44 y/o female. FNA of thyroid. A. Unsatisfactory due to insufficient

cellularity.B. Lymphocytic thyroiditis.C. GoiterD. Indeterminate.E. Papillary carcinoma. 1

Mixture of lymphocytes and Mixture of lymphocytes and follicular cells.follicular cells.

Page 3: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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Bronchoalveolar lavage.A. Unsatisfactory.B. Malignant cells present.C. PCP D. StrongyloidesE. Artifact

Page 4: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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Thyroid FNAA. Colloid with cholesterol crystals.B. Indeterminate.C. Papillary carcinoma.D. Anaplastic carcinoma.E. Metastatic carcinoma.

Large rectangular cholesterol crystals commonly seen in goiter

Page 5: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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FNA of thigh mass.A. Negative for malignancy.B. Sq. cell carcinoma.C. AdenoCa.D. Sarcoma.E. Abscess.

Some of the malignant cells are splindled.

Others are large and hyperchromatic.

Page 6: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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Bronchoalveolar lavage.A. Unsatisfatory.B. Negative for malignancy.C. Small cell carcinomaD. AdenoCaE. Squamous cell carcinoma

Benign ciliated bronchial cell

Pigmented macrophages are needed for an adequate sample

Page 7: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

FNA of thyroid.A. Reactive, neg for malignancyB. GoiterC. Indeterminate for malignancy.D. Papillary carcinoma.E. Follicular carcinoma.

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Intranuclear inclusion

This papillary structure viewed at high power demonstrates cells with high N/C ratios, hyperchromasia, and intranuclear inclusions.

Page 8: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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54 yo female with pleural effusionA. Reactive mesothelial cellsB. AdenocarcinomaC. MesotheliomaD. Melanoma E. Lymphoma

This “cannon ball” of tumor cells is characteristic for breast carcinoma in pleural fluid. Other adenocarcinomas may form large proliferation spheres as well. Adenoca’s have smooth community borders, whereas mesotheliomas tend to have a more knobby outline.

Page 9: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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FNA of pancreatic mass.A. Unsatisfactory specimenB. Reactive cellsC. Pseudocyst contentsD. Pancreatic adenocarcinomaE. Amebiasis

Compare the malignant cells to the reactive ductal cells arranged in a orderly honeycomb pattern. The malignant cells are less cohesive. Did you notice the tumor diathesis in the background?

Page 10: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

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GMS of corneal scrapeA. PCPB. AcanthamoebaC. FungusD. Fuch’s corneal dystrophyE. Toxic epidermal necrolysis

Acanthamoeba has a spiky outline.

Page 11: Oct 31, 2008. 44 y/o female. FNA of thyroid. A.Unsatisfactory due to insufficient cellularity. B.Lymphocytic thyroiditis. C.Goiter D.Indeterminate. E.Papillary

61 yo bladder wash s/p TURP.A. Benign changes. B. FungusC. Smooth muscle neoplasmD. SchistosomiasisE. High grade TCC 10

Instrumentation effect.