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Max CARNECCHIA

BIOVIA CEO

BIOVIA Overview

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Introduction

BIOVIA Overview and Vision

Science Driving Innovation

Customer Stories

Agenda

Opportunities and Challenges In The Market

• Sanofi• Baxter• P&G• Shell• ExxonMobil• Boeing

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Executive Director of Process Development, Digital Integration

and Predictive Technologies & CMC at Amgen

Cenk Undey, Ph.D.

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BIOVIA Mission

Virtual BioSphere and Materials

PictureBIOVIA provides a scientific collaborative environment for

advanced biological, chemical and materials experiences.

The sophisticated enterprise system of modeling, simulation,

laboratory and quality management enables innovation for

science-based industries.

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BIOVIA – Today

Support Next Generation

Scientific Innovation

Address

Science-driven IndustriesProvide Enterprises

Chemical/Biological/Material

360° Experiences

Social Industry Experiences

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• Life Science Discovery and Material Research best of breed technologies

• Accelrys, a public company

with a focused collection of

early research products

• Transform Accelrys to a Scientific

Innovation Lifecycle Management (SILM)

software company

20142004C.1990 2010

BIOVIA – The Future

Toward Accelrys

Creating Accelrys

Transforming Accelrys

2012 2016

• 3DS PLM On V6

architecture

• Integration of BIOVIA + 3DS

• bioPLM – next generation

• BIOVIA scientific workflows

become 3D experiences

• BIOVIA expansion across 3DS

brands and industries

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BIOVIA Customers in Diversified Markets

ACADEMIA

AEROSPACE & DEFENSE

TRANSPORTATION & MOBILITY

HIGH-TECH

CONSUMER PACKAGED GOODS - RETAIL

ENERGY, PROCESS & UTILITIES

LIFE SCIENCES

GOVERNMENT

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BIOVIA - Solving Industry Specific Challenges

Over 2,000 customers

• 10 of the top 10 pharmaceutical

• 20 of the top 25 biotech

• 7 of the top 10 chemical

• 4 of the top 5 consumer packaged goods

• 5 of the top 10 oil & gas

• 5 of the top 5 aerospace

• Government and academic institutions

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Macro Trends Driving Change

• Expanding externalization

• Rapidly growing global markets

• Increasingly complex and interconnected

value chains

• Growing regulations

• Emerging new technologies

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Entity &

Formula

Closed-loop &

Integrated Business

Delivering on the promise of Performance & QualitySpecifications &

Regulatory

Initiative &

Portfolio

Compliance &

Quality

Process Design

& Scale-up

Test Labs &

Development

DiscoveryChemistry

Biology

Materials

Innovation Value Chain

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BIOVIA – Covering the Scientific Innovation Lifecycle

• Collaborative Science

• Unified Lab Management

• Process Production Operations

• Quality and Regulatory Management

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BIOVIA – Dassault Systèmes

• Dassault Systèmes is Committed to Science

• Invested significantly into science-based innovation

• Committed to long-term strategy and positioning

• BIOVIA’s Strategy is Aligned to Customer Business Goals

• Reduce overall costs and improve productivity with an open and

flexible foundation for end-to-end processes

• Innovate faster and improve sharing information for accessing data

and information across domains

• Partnership with Dassault Systèmes is Secure

• One of the 10 largest software providers worldwide

• Up to 22% to R&D for continued development

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BIOVIA Summary

• Focused on key science-related innovation initiatives

• Strong experience from pure research to

manufacturing

• Enterprise-class solutions for 10s to 1000s of users

• Deeply invested in science – over 225 PhD Scientists

Science-driven Approach Unique Solutions – Strategic Partner

• Partnering with world-leading organizations to develop

new innovations with software and services

• Focusing on new products and business through

industry drivers, workflow and market pressure

• Providing scalability, integration and data exchange

Global Footprint – Global Partner

• Strong direct presence in Americas, Asia Pacific and

Europe for consulting, education and support

• >50% of revenues from outside the US

Strong Investments

• Approximately 22% of revenue invested in organic R&D

• Proven M&A execution

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Reza Sadeghi. Ph.D.

Science Driving (Sustainable) Innovation

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Today…

to produce 100 bushels

of wheat in the US

>3 Hours

& by 2040?

50 years ago…

to produce 100 bushels of

wheat in the US

<50 Hours

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Science Driving Innovation

• Sustainable formulations that

scale across global regions

• Cleaners, surfactants,

solvents, perfumes, dyes, etc.

• Packaging materials and

textiles

CONSUMER PACKAGED GOODS

• Cleaner petrol products and

processes, e.g. catalytic

cracking, reaction design, etc.

• Catalyst surfaces for fuel cells

• Green and stable battery

cathodes, anodes,

electrolytes, paint

ENERGY / UTILITIES

• Polymers and composite

matrix/resins

• Nano-enhanced composites,

polymers and alloys

• Advanced materials and

delivery for 3D printing

• Stable, longer-lasting batteries

AEROSPACE / AUTOMOTIVE

• Drug discovery, design,

delivery, efficacy, and safety

• Biological entities development

• Clinical trials / systems biology

• Streamlined regulatory and

corporate compliance

LIFE SCIENCES

• Smaller semiconductor fab

nodes (14nm and smaller)

• Biology-on-chip polymers and

bio-materials

• Longer-lasting batteries

HIGH-TECH

Oth

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ey In

dust

ries

…

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Discovery to Commercialization

► Idea to market for a new drug still takes a decade maybe more …

► Other materials take up to 2 decades ...

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Drug Discovery

Year 0 2 74 63

Parameter space has

increased a million-fold

More virtual capabilities &

targeted experiments needed

to efficiently explore all

options

Easy ones

have been

found

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Scientific

Breakthroughs

BIOVIA Portfolio & Science

Sustainable

Innovations

Virtualization

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Science: Sustainable Competitive Advantage

Regenerative Medicine

Personal

HealthNano

TechnologyDigital

Tattoos

Cellular “Ink”

Next Gen Materials

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Virtual Material Discovery

MATERIALENGINEERING

Steels, Light Alloys, W, Cu, Nb, DU, etc.

TRADITIONAL

ENGINEEREDMATERIALS

Nano, Multifunctional, Biomimetic, Self healing, Self

replicating, etc.

FUTURE

COMPOSITES / POLYMERS

Carbon Laminates, Kevlar, Rayon, PBT, etc.

TODAY

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Advanced Composites & Next Generation Materials

TODAY

Aerospace

Automotive

Technology Focus

• New polymer matrix

• High performance fibers

• New and “green” polymers & chemicals

(coatings, catalysts, solvents, etc)

Energy Apparel

Life Sciences

High Tech

Carbon Nanotube

FUTURE

Buckypaper Graphene

Smart Textiles

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A Simple Message

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