One Nucleus

What is One Nucleus?

A membership organisation

• Funded by sponsorship, membership fees, events and projects

• Based in Cambridge and London but with global members

• Formed by merger of ERBI and LBN

With more than 470 members

• Biotech, pharma, medical device, diagnostics

• Technical and commercial service providers

• 30% Gold, 70% Silver

VisionFor One Nucleus and our members to be the top European life science and healthcare network

MissionTo maximise the global competitiveness of our members

Focused 100% on delivering value to members

Key Technology Strengths

• Global biotech centre of excellence

– Many key scientific discoveries made in Cambridge or London

– Drug and biological therapy development

• Global engineering centre of excellence

– Electronics and processors

– Wireless connectivity

– Software and data management

– Much of the world’s medical technology developed in Cambridge-Royston corridor

• Biotech/medtech convergence

– Devices to deliver biotech innovation

– Drug delivery, diagnostics

Convergence of stakeholders

• Up to 60 % of clinical trials in Europe are carried out in the UK, the majority of those in London.

• London is home to 3 of the 5 comprehensive and 4 of the 6 specialist biomedical centres of the National Institute for Health Research; 17 of the MRC’s units centres and institutes; and CRUK’s London Research Institute.

• More biotechnology venture capital groups than the next 10 largest European cities.

Life Sciences Hub Linkages

Norwich Research Park

Babraham ResearchCampus

BioPark

Colworth Research Park

Papworth and Addenbrookes

GSK

Networking and Partnering

Cambridge BioCluster

London Bio and finance

cluster

BioParkCluster,Welwyn

Garden City

Stevenage BioCatalyst

& GSK

Francis Crick Institute planned for 2015

£800M initiative

J&J Innovation Centre 2013

AstraZeneca relocate UK presence 2013

Babraham Campus expansion 2013/14

London Mayor announces Med City 2013

One Nucleus

Bio - Therapeutics

Bio- services

Pharma

Med Tech

Investors

Not-for profit

IP Services

Legal Services

BD Advisors

Drug Developnent Consulting

Financial Services

Other Professional Services

What do our members do?

• Regular member meetings

– Cambridge Network Meetings

– London BioWednesdays

– Socials in both locations

• Cambridge Life Science Leadership Series 2012 (x 3)

• ON Helix Conference

• Genesis Conference

Networking and Partnering

Genesis Conference

• 9 Dec 2014, London, UK with 650+ delegates for thought leadership debate, exhibition and 1-2-1 partnering

• Programme Partner – Scrip Intelligence

• Inward missions from France, Canada, Germany, Spain, Italy, and US planned

• www.genesisconference.com

• Courses based on identified skills gaps:

– Introduction to drug development

– Introduction to management

– Commercial awareness

– Presentation skills for scientists

– Project management

– Laboratory health and safety

– Health and safety for representatives and managers

– Directing safety (IOSH accredited)

• Rates for members and non-members

• Courses also in London and Manchester

• Courses are CPD accredited

Training

• Small groups to discuss key business issues

– Human resources

– Project management

– Corporate governance

– Business development

– IP

– IT

– Regulatory affairs/clinical development

– Corporate communications

– Operations (combining security, health and safety, Purchasing)

– Training

Special Interest Groups

• Preferred Supply Agreements (tendered, exclusive) – now includes BioNow members:– Stationery & IT consumables– Pipette maintenance & calibration– Bulk gases, cylinder gases and dry Ice– Laboratory consumables and chemicals– Life science products– Laboratory equipment maintenance

• Support Supply Agreements (not tendered or exclusive)– Courier services, stationery, hotels, insurance, travel, cleaning

• £3 million annual savings• Example 1

– £20,000 saving on top 40 moist used lab consumables– “The cost saving alone makes it worth joining”

• Example 2– £49,559 saving (42%) against Fisher Scientific list prices vs £2,000 annual

membership cost

• Example 3– £8,000 pa cost saving (12%) on equipment maintenance plus improved service

levels and payment terms

• Example 4– £1,371 rebate under office supplies contract

• Example 5– £3,267 saving by switching annual dry ice spend

Purchasing Scheme

• Formal MOU relations with:

– MassBIO, MassMedic on East coast US

– BayBIO and BIOCOM on West coast US

– Practical support for members engaging with overseas clusters and companies

• EU projects

– CEBR

– eLSi

– One-on-One

International

BIO 2013 Dinner

Current Developments

• Convergence

- Technology and Business

• International relationships

- tangible outcomes, managed, focus

• M11 Med Tech Forum

- Key London-Cambridge link

- Complements the UK MediLink Coverage

- Quarterly events, wider One Nucleus engagement

• One Nucleus Life Science Hubs

- access for life science execs when travelling

One network for biotech, pharma, medical device and diagnostic businesses

One network for Cambridge and London

There is only One Nucleus