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Table of Contents Opening session & Keynote addresses ............................................................................................................................................... 1 Breast cancer ...................................................................................................................................................................................... 2 CNS tumours ....................................................................................................................................................................................... 4 Developmental therapeutics .............................................................................................................................................................. 6 Gastrointestinal tumours .................................................................................................................................................................... 8 Genitourinary tumours ..................................................................................................................................................................... 11 Gynaecological cancers ..................................................................................................................................................................... 13 Haematological malignancies ........................................................................................................................................................... 15 Head & Neck cancer .......................................................................................................................................................................... 17 Melanoma & immunotherapy .......................................................................................................................................................... 19 Sarcoma ............................................................................................................................................................................................ 21 Supportive & palliative care .............................................................................................................................................................. 23 Thoracic cancers ............................................................................................................................................................................... 25 Best of 2015 ...................................................................................................................................................................................... 27 Special sessions ................................................................................................................................................................................. 28 Joint Symposia .................................................................................................................................................................................. 30 ESMO Clinical Practice Guideline Sessions ........................................................................................................................................ 32

Opening session & Keynote addresses Friday, 18 December 2015 – 11:00-12:30

Title Opening session Chair Rolf A. Stahel, CH Co-Chair Fortunato Ciardiello, IT Title presentation 1 Welcome speeches Speaker 1 Rolf A. Stahel, CH and Fortunato Ciardiello, IT Lecture/disc time 1 40’ Title presentation 2 Keynote lecture: Molecular biology: The immune response Speaker 2 Tasuku Honjo, JP Lecture time 2 25’ Title presentation 3 Keynote lecture: P53 Speaker 3 David Lane, SG Lecture/disc time 3 25’

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Breast cancer Chair: Fabrice André, FR Scientific committee members: Sherene Loi, AU Kenji Tamura, JP Sibylle Loibl, DE Zefei Jiang, CN Masakazu Toi, JP Sung Bae Kim, KR Educational session 1 – 90 mins Friday, 18 December 2015 - 14:30-16:00

Title Optimal endocrine therapy in pre-menopausal women Chair Sibylle Loibl, DE Co-Chair To be announced Title presentation 1 Which endocrine therapy? Speaker 1 Prudence Francis, AU Lecture/disc time 1 30’ Title presentation 2 Duration of endocrine therapy and modality of patient selection Speaker 2 Sung-Bae Kim, KR Lecture time 2 30’ Title presentation 3 Pregnancy during endocrine therapy Speaker 3 Sibylle Loibl, DE Lecture/disc time 3 30’ Educational session 2 – 90 mins Saturday, 19 December 2015 – 09:00 – 10:30

Title Emerging systemic treatment in TNBC Chair Rebecca Dent, SG Co-Chair To be announced Title presentation 1 How can we personalise treatment options for patients with TNBC?

(gene arrays - BRCA mutations - ER status) Speaker 1 Kenji Tamura, JP Lecture/disc time 1 15’ Title presentation 2 DNA interacting drugs Speaker 2 Rebecca Dent, SG Lecture/disc time 2 25’ Title presentation 3 Targeting androgene receptors (molecular characterisation – genomic landscape) Speaker 3 Hervé Bonnefoi, FR Lecture time 3 25’ Title presentation 4 Immunotherapeutics Speaker 4 Sherene Loi, AU Lecture/disc time 4 25’

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Challenge Your Expert session - 45 mins Sunday, 20 December 2015 – 08:00 – 08:45

Title When and how to use the CDK4/6 inhibitor in metastatic breast cancer Speaker Masakazu Toi, JP Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience Patient cases (Tumour board) - 90 mins Monday, 21 December 2015 – 11:00-12:30

Topic Treatment decrease in early breast cancer Tumorboard Panel Sudeep Gupta, IN

Seock-Ah Im, KR Roman Rouzier, FR

Title presentation 1 How to use genomic testing in early breast cancer Case 1: non-positive Case 2: non-negative

Speaker 1 Sudeep Gupta, IN Lecture/disc time Maximum 20’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 25’ discussion time with audience Title presentation 3 The role of lymph node dissection and SLN biopsy

Case 1: Neoadjuvant breast cancer patients Case 2: Primary patient with TNBC and positive SLN

Speaker 3 Roman Rouzier, FR Lecture/disc time Maximum 20’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 25’ discussion time with audience Special Symposium - 90 mins Saturday, 19 December 2015 – 11:00 – 12:30

Title symposium Clinical relevance of genotyping ER positive breast cancer Chair Fabrice André, FR Co-Chair Janice Wing-Hang Tsang, HK Title presentation 1 Introduction Speaker 1 Fabrice André, FR Lecture time 1 5’ Title presentation 2 ESR1 mutations Speaker 2 Takayuki Iwamoto, JP Lecture/disc time 2 20’ Title presentation 3 Genomic alteration of the PI3K/AKT pathway Speaker 3 Fabrice André, FR Lecture/disc time 3 20’ Title presentation 4 Emerging treatment options in the genomic era Speaker 4 Janice Wing-Hang Tsang, HK Lecture/disc time 4 20’ Title presentation 5 Should I order sequencing for my patients with ER positive metastatic breast cancer? Speaker 5 Soonmyeong Paik, KR Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Janice Wing-Hang Tsang, HK Lecture/disc time 6 5’

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CNS tumours Chair: Roger Stupp, CH Scientific committee members: Zhong-Ping Chen, CN Do-Hyun Nam, KR Rakesh Jalali, IN Ryo Nishikawa, JP Educational session – 90 mins Saturday, 19 December 2015 – 11:00 – 12:30

Title Clinical implications of molecular advances Chair Roger Stupp, CH Co-Chair Chee Kian Tham, SG Title presentation 1 Glioma: Current status & novel insights Speaker 1 Roger Stupp, CH Lecture/disc time 1 30’ Title presentation 2 How to treat germ cell tumours Speaker 2’ Danny T.M. Chan, HK Lecture/disc time 2’ 30’ Title presentation 3 Molecular biology Speaker 3 Michael D. Taylor, CA Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Saturday, 19 December 2015 – 08:00 – 08:45

Title The limits of radical resection Speaker Nader Sanai, US Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Patient cases (Tumour board)- 90 mins Friday, 18 December 2015 - 14:30-16:00

Topic Clinical challenges in neuro-oncology Tumorboard Panel Kei Sai, CN

Yoko Nakasu, JP Danny T.M. Chan, HK, CN Rakesh Jalali, IN Roger Stupp, CH

Title presentation 1 When the MRI is misleading: How to evaluate tumour response, progression vs pseudoresponse and pseudoprogression

Speaker 1 Ke Sai, CN Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Brain metastases: (When & how) To treat or not to treat? Speaker 3 Yoko Nakasu, JP

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 Young patient with progressive low-grade glioma Speaker 5 Danny T.M. Chan, HK, CN Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience Special Symposium - 90 mins

Friday, 18 December 2015 - 16:30-18:00

Title symposium Innovative approaches in neuro-oncology Chair Rakesh Jalali, IN Co-Chair To be announced Title presentation 1 Introduction Speaker 1 Rakesh Jalali, IN Lecture time 1 5’ Title presentation 2 Personalised medicine: n=1 trials and their clinical implication Speaker 2 Do Hyun Nam, KR Lecture/disc time 2 20’ Title presentation 3 Novel tools or toys in radiation oncology: Is there any impact? Speaker 3 Rakesh Jalali, IN Lecture/disc time 3 20’ Title presentation 4 How to break the immune tolerance in brain tumours Speaker 4 Michael Weller, CH Lecture/disc time 4 20’ Title presentation 5 Meningioma, mostly cured, occasionally deadly. Progress and challenges Speaker 5 Christian Mawrin, DE Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Co-Chair Lecture/disc time 6 5’

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Developmental therapeutics Chair: Tony S.K. Mok, CN Scientific committee members: Alex Adjei, US Christian Dittrich, AT Josep Tabernero, ES Daniel Tan, SG Educational session – 90 mins Sunday, 20 December 2015 – 09:00–10:30

Title Novel strategy to accelerate drug development Chair Alex A. Adjei, US Co-Chair Boon Cher Goh, SG Title presentation 1 Master protocol & basket protocol Speaker 1 Daniel Tan, SG Lecture/disc time 1 30’ Title presentation 2 Novel drug development for tumours with no molecular aberrations Speaker 2 Alex A. Adjei, US Lecture time 2 30’ Title presentation 3 Proof of concept of algorithm based strategy Speaker 3 Christophe Le Tourneau, FR Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Monday, 21 December 2015– 08:00–08:45

Title Data tsunami as a limiting step in using the all omics approach Speaker Yu Shyr, US Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Special Symposium 1 90 mins Saturday, 19 December 2015 – 11:00-12:30

Title symposium Drug development: East meets West Chair Tony S.K. Mok, CN Co-Chair Christian Dittrich, AT Title presentation 1 Introduction Speaker 1 Christian Dittrich, AT Lecture time 1 5’ Title presentation 2 Drug development and drug approval paradigms in Europe Speaker 2 Hans-Georg Eichler, UK Lecture/disc time 2 25’ Title presentation 3 Drug development and drug approval paradigms in Asia Speaker 3 Alex Matter, SG Lecture/disc time 3 25’ Title presentation 4 Challenges of an integrated global drug development programme Speaker 4 Serban Ghiorghiu, US

Lecture/disc time 4 25’ Title presentation 5 Conclusions and clinical perspectives Speaker 5 Tony S.K. Mok, CN Lecture/disc time 5 10’ Special Symposium 2 - 90 mins Monday, 21 December 2015 – 11:00-12:30

Title symposium New promising targets Chair Jean-Pierre Armand, FR Co-Chair Li Zhang, CN Title presentation 1 Introduction Speaker 1 Jean-Pierre Armand, FR Lecture time 1 5’ Title presentation 2 Biotech and early drug development in immunotherapy in China Speaker 2 Li Zhang, CN Lecture/disc time 2 20’ Title presentation 3 PARP Speaker 3 Hilary Calvert, UK Lecture/disc time 3 20’ Title presentation 4 CDK Speaker 4 Christian Dittrich, AT Lecture/disc time 4 20’ Title presentation 5 Epigenetic targets Speaker 5 Qian Tao, HK Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Li Zhang, CN Lecture/disc time 6 5’

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Gastrointestinal tumours Chair: Yung-Jue Bang, KR Scientific committee members: Dirk Arnold, DE Ian Chau, UK Jin Li, CN Atsushi Ohtsu, JP Eric Van Cutsem, BE Ann Lii Cheng, TW Educational session 1 – 90 mins Friday, 18 December 2015 - 14:30-16:00

Title Gastrointestinal cancer I Chair Patrick Tan, SG Co-Chair Jin Li, CN Title presentation 1 How would cancer genomics guide our therapeutic development in gastric cancer? Speaker 1 Patrick Tan, SG Lecture/disc time 1 30’ Title presentation 2 Systemic treatment of advanced gastric cancer Speaker 2 Yung-Jue Bang, KR Lecture time 2 30’ Title presentation 3 Multimodal treatment in advanced pancreatic cancer

(Speaker to address combination of chemo +/- RT +/- surgery in both, local advanced disease and/or oligometatsatic disease)

Speaker 3 Manuel Hidalgo, ES Lecture/disc time 3 30’ Educational session 2 – 90 mins Saturday, 19 December 2015 – 14:30-16:00

Title Gastrointestinal cancer II Chair Dirk Arnold, DE Co-Chair Ann-Lii Cheng, TW Title presentation 1 Applying the ESMO Colorectal Cancer Consensus to different clinical scenarios and health care

systems Speaker 1 Dirk Arnold, DE Lecture/disc time 1 30’ Title presentation 2 Tracking clonal evolution and adapting therapy in metastatic colorectal cancer Speaker 2 Nicola Normanno, IT Lecture time 2 30’ Title presentation 3 Hepatocellular carcinoma: Why aren´t we making progress with systemic treatment and what is

the role of ablative strategies? Speaker 3 Thomas Yau, CN Lecture/disc time 3 30’

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Challenge Your Expert session - 45 mins Saturday, 19 December 2015 – 08:00–08:45

Title Hepatocellular carcinoma Speaker Ann-Lii Cheng, TW Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience Patient cases (Tumour board) - 90 mins Friday, 18 December 2015 – 16:30-18:00

Topic GI tumours Tumorboard Panel Dirk Arnold, DE

Do-Youn Oh, KR Atsushi Ohtsu, JP Marianne Pavel, DE

Title presentation 1 Cholangiocarcinoma (e.g. locally advanced unresectable intrahepatic cholangiocarcinoma, role of chemotherapy, radiotherapy, hepatic ablative therapy and SIRT, liver transplant)

Speaker 1 Do-Youn Oh, KR Lecture/disc time Maximum 7’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 CRC

(e.g. T3NO rectal cancer, RT or not, ?avoid surgery after CRT, what if any adjuvant chemotherapy after Surgery)

Speaker 3 Dirk Arnold, DE

Lecture/disc time Maximum 7’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 NETs

(e.g. recurrent or persistent carcinoid crisis from NET or sequencing of chemotherapy and targeted therapy for PNET)

Speaker 5 Marianne Pavel, DE

Lecture/disc time Maximum 7’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 7 Esophageal SCC

(e.g. treatment beyond radical radiotherapy or surgery) Speaker 7 Atsushi Ohtsu, JP

Lecture/disc time Maximum 7’ Title presentation 8 Tumour board discussion Speaker 8 Panellists Lecture/disc time Maximum 15’ discussion time with audience

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Special Symposium - 90 mins Monday, 21 December 2015 – 09:00-10:30

Title symposium Translating emerging therapeutics into clinical use Chair Atsushi Ohtsu, JP Co-Chair Ian Chau, UK Title presentation 1 Introduction Speaker 1 Atsushi Ohtsu, JP Lecture time 1 5’ Title presentation 2 Manipulating immune system in GI cancer Speaker 2 Benoît Van den Eynde, BE Lecture/disc time 2 15’ Title presentation 3 Targeting angiogenesis in GI cancers

(speaker to compare positive studies (CRC, GC) and negative studies (other GI) Speaker 3 Kei Muro, JP Lecture/disc time 3 15’ Title presentation 4 GI cancer stem cells: Rationale and clinical implications Speaker 4 Kohei Shitara, JP Lecture/disc time 4 15’ Title presentation 5 Are the latest drugs fit for purpose in MAPK/ERK and PI3K signalling pathways? Speaker 5 Fortunato Ciardiello IT Lecture/disc time 5 15’ Title presentation 6 What lessons can we learn from targeting cMET and IGFR in GI cancers? Speaker 6 Ian Chau, UK Lecture/disc time 6 15’ Title presentation 7 Conclusions and clinical perspectives Speaker 7 Ian Chau, UK Lecture/disc time 7 10’

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Genitourinary tumours Chair: Johann de Bono Scientific committee members: Kim Chi, CA Ian Davis, AU Karim Fizazi, FR Ravindran Kanesvaran, SG Bin Tean Teh, SG Oliver Sartor, US Educational session 1 Prostate – 90 mins Saturday, 19 December 2015 - 09:00–10:30

Title Prostate cancer: State of a rapidly evolving art Chair Oliver Sartor, US Co-Chair To be announced Title presentation 1 Management of localised disease, risk stratification and progress Speaker 1 Laurence Klotz, CA Lecture/disc time 1 30’ Title presentation 2 Advances in hormonal therapy Speaker 2 Carmel Pezaro, AU Lecture time 2 30’ Title presentation 3 Advances in non-hormonal therapy Speaker 3 Oliver Sartor, US Lecture/disc time 3 30’ Educational session 2 Non-prostate – 90 mins Saturday, 19 December 2015 – 16:30-18:00

Title Advances in the concept and management of GU malignancies Chair Bin Tean Teh, SG Co-Chair Ravindran Kanesvaran, SG Title presentation 1 Immunology / Immunotherapy for urological malignancies: Bladder and renal Speaker 1 Winald Gerritsen, NL Lecture/disc time 1 30’ Title presentation 2 Emerging cancer genomics Speaker 2 Bin Tean Teh, SG Lecture time 2 30’ Title presentation 3 Management of the patient presenting with oligometastases Speaker 3 Axel Heidenreich, DE Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Monday, 21 December 2015 – 08:00-08:45

Title Challenges in the systemic treatment of GU malignancy Speaker Ian Davis, AU Lecture/disc time 3 Presentation maximum 25-30’. Minimum 20-15’ Discussion time with audience

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Patient cases (tumour board) - 90 mins (2 x 45’ sections) Sunday, 20 December 2015 – 09:00–10:30

Topic Genitourinary tumours Tumorboard Panel Kim Chi, CA

Ian Davis, AU Paul DeSouza, AU Mark Rubin, US Yoshihiko Tomita, JP

Title presentation 1 Improving outcome from lethal prostate cancer Speaker 1 Kim Chi, CA Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 30’ discussion time with audience Title presentation 3 Medical treatment of mRCC Speaker 3 Yoshihiko Tomita, JP

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 30’ discussion time with audience Special Symposium - 90 mins Friday, 18 December 2015 - 14:30-16:00

Title symposium Improving outcome from castration-resistant prostate cancer Chair Kim Chi, CA Co-Chair Karim Fizazi, FR Title presentation 1 Introduction Speaker 1 Kim Chi, CA Lecture time 1 5’ Title presentation 2 Molecular pathology Speaker 2 Mark Rubin, US Lecture/disc time 2 20’ Title presentation 3 Improving the treatment of CRPC: Drugs, sequencing and stratification Speaker 3 Karim Fizazi, FR Lecture/disc time 3 20’ Title presentation 4 Circulating biomarkers in metastatic prostate cancer Speaker 4 Kim Chi, CA Lecture/disc time 4 20’ Title presentation 5 Imaging metastatic castration resistant prostate cancer Speaker 5 Anwar Padhani, UK Lecture/disc time 5 20’ Title presentation 6 Conclusions Speaker 6 Kim Chi, CA Lecture/disc time 6 5’

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Gynaecological cancers Chair: Keiichi Fujiwara, JP Scientific committee members: David Bowtell, AU Andrés Cervantes, ES Robert L. Coleman, US Stan Kaye, UK David Tan, SG Educational session – 90 mins Saturday, 19 December 2015 – 14:30-16:00

Title Optimal multi-modality therapy for gynaecological cancers Chair Jonathan Ledermann, UK Co-Chair David Tan, SG

Title presentation 1 Ovarian cancer Speaker 1 Jonathan Ledermann, UK Lecture/disc time 1 30’ Title presentation 2 Cervical cancer Speaker 2 Bradley Monk, US Lecture time 2 30’ Title presentation 3 Endometrial cancer Speaker 3 David Miller, US Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Saturday, 19 December 2015 – 08:00–08:45

Title Optimal first-line treatment for ovarian cancer Speaker Robert Coleman, US Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Patient cases (Tumour board) - 90 mins Saturday, 19 December 2015 - 09:00–10:30 Topic Challenging subtypes in gynaecological cancer Tumorboard Panel Robert Coleman, US

Khai Mun Lee, SG Mansoor Raza Mirza, DK David Tan, SG

Title presentation 1 Endometrial / uterine carcinosarcoma Speaker 1 Mansoor Raza Mirza, DK Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Stage II clear cell progressing Speaker 3 David Tan, SG

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 Small cell carcinoma of the cervix Speaker 5 Robert Coleman, US

Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience Special Symposium - 90 mins Friday, 18 December 2015 – 16:30-18:00

Title symposium Precision medicine and developmental therapeutics in gynaecologic oncology Chair David Bowtell, AU Co-Chair Stan Kaye, UK Title presentation 1 Introduction Speaker 1 David Bowtell, AU Lecture time 1 5’ Title presentation 2 Therapeutic relevance of gene expression signatures in ovarian cancer: Examining the evidence Speaker 2 Ruby Huang, SG Lecture/disc time 2 20’ Title presentation 3 New insights into resistance of treatment Speaker 3 David Bowtell, AU Lecture/disc time 3 20’ Title presentation 4 Immunotherapy for gynaecological cancers: Challenges and opportunities Speaker 4 Junzo Hamanishi, JP Lecture/disc time 4 20’ Title presentation 5 Targeted therapies for gynaecological cancers Speaker 5 Michael Friedlander, AU Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Stan Kaye, UK Lecture/disc time 6 5’

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Haematological malignancies Chair: Michele Ghielmini, CH Scientific committee members: Martin Dreyling, DE Zhi-Ming Li, CN Masao Seto, JP Lena Specht, DK Educational session – 90 mins Sunday, 20 December 2015 – 11:00–12:30

Title Impact of PET on lymphoma management Chair Andrea Gallamini, IT Co-Chair To be announced Title presentation 1 The Lugano Lymphoma classification and the new criteria for PET evaluation Speaker 1 Martin Hutchings, DK Lecture/disc time 1 30’ Title presentation 2 The role of interim PET in Hodgkin and non-Hodgkin lymphomas Speaker 2 Andrea Gallamini, IT Lecture time 2 30’ Title presentation 3 The role of end-of-treatment PET in lymphoma management Speaker 3 Ulrich Dührsen, DE Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Saturday, 19 December 2015 – 08:00–08:45

Title Modern radiotherapy in the combined modality treatment of lymphomas Speaker Lena Specht, DK Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Patient cases (Tumour board) - 90 mins Saturday, 19 December 2015 – 11:00–12:30

Topic T cell lymphoma Tumorboard Panel Francesco d’Amore, DK

Kensei Tobinai, JP Won Seog Kim, KR Ye-Xiong Li, CN Soon Thye Lim, SG

Title presentation 1 Localised NK/T cell lymphoma Speaker 1 Ye-Xiong Li, CN Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Peripheral T cell lymphoma Speaker 3 Kensei Tobinai, JP

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 Angioimmunoblastic T cell lymphoma Speaker 5 Won Seog Kim, KR

Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience

Special Symposium - 90 mins Sunday, 20 December 2015 – 14:30-16:00

Title symposium Chemotherapy-free lymphoma treatment Chair Michele Ghielmini, CH Co-Chair To be announced Title presentation 1 Introduction Speaker 1 Michele Ghielmini, CH Lecture time 1 5’ Title presentation 2 Monoclonal antibodies alone and in combination Speaker 2 Zhi-Ming Li, CN Lecture/disc time 2 20’ Title presentation 3 BCR-receptor pathway inhibitors Speaker 3 Simon Rule, UK Lecture/disc time 3 20’ Title presentation 4 IMID and antiapoptotic agents Speaker 4 Constantine Tam, AU Lecture/disc time 4 20’ Title presentation 5 Immunotherapy Speaker 5 Anas Younes, US Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Co-Chair Lecture/disc time 6 5’

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Head & Neck cancer Chair: Anthony T.C. Chan Scientific committee members: Lisa Licitra, IT Amanda Psyrri, GR Makoto Tahara, JP Joseph Wee, SG Educational session – 90 mins Sunday, 20 December 2015 – 14:30-16:00

Title Challenges in quality of life in head and neck cancer Chair Lisa Licitra, IT Co-Chair To be announced Title presentation 1 Challenges in value based medicine (evidence / patient preference) Speaker 1 Lisa Licitra, IT Lecture/disc time 1 30’ Title presentation 2 The surgical value Speaker 2 Christian Simon, CH Lecture time 2 30’ Title presentation 3 The value of radiation Speaker 3 Vincent Grégoire, BE Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Sunday, 20 December 2015 – 08:00 – 08:45

Title Management of HPV-associated oropharyngeal cancer Speaker Amanda Psyrri, GR Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Patient cases (Tumour board) - 90 mins Saturday, 19 December 2015 - 09:00–10:30

Topic Controversial issues in managing locally advanced head and neck cancer Tumorboard Panel Anil D’Cruz, IN

Boon Cher Goh, SG Jiade Lu, CN Makoto Tahara, JP

Title presentation 1 Thyroid cancer Speaker 1 Makoto Tahara, JP Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Oral cavity cancer Speaker 3 Anil D’Cruz, IN

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 Locally recurrent NPC Speaker 5 Jiade Lu, CN

Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience Special Symposium - 90 mins Sunday, 20 December 2015 – 16:30-18:00

Title symposium Nasopharyngeal cancer Chair Anthony T.C. Chan, CN Co-Chair Joseph Wee, SG Title presentation 1 Introduction Speaker 1 Anthony T.C. Chan, CN Lecture time 1 5’ Title presentation 2 Review of NPC meta-analysis Speaker 2 Bertrand Baujat, FR Lecture/disc time 2 20’ Title presentation 3 EBV DNA risk stratification strategies Speaker 3 Anthony T.C. Chan, CN Lecture/disc time 3 20’ Title presentation 4 Adoptive immunotherapy and vaccines Speaker 4 Neil Steven, UK Lecture/disc time 4 20’ Title presentation 5 Molecular targeting approaches Speaker 5 Brigette B. Ma, CN Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Joseph Wee, SG Lecture/disc time 6 5’

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Melanoma & immunotherapy Chair: Ignacio Melero, ES Scientific committee members: George Coukos, CH Alexander MM Eggermont, FR Peter Hersey, AU Grant McArthur, AU Koji Tamada, JP Thomas Tüting, DE Educational session – 90 mins Sunday, 20 December 2015 – 09:00–10:30

Title Breakthroughs in immuno-oncology Chair Ugur Sahin, DE Co-Chair To be announced Title presentation 1 Immune recognition of tumours and mutational antigens: Opportunities for the future Speaker 1 Ugur Sahin, DE Lecture/disc time 1 30’ Title presentation 2 Combination immunotherapy Speaker 2 Michele Teng, AU Lecture time 2 30’ Title presentation 3 Adoptive T cell therapy Speaker 3 John Haanen, NL Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Sunday, 20 December 2015 – 08:00 – 08:45

Title How to personalise immunotherapy of cancer Speaker George Coukos, CH Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Patient cases (Tumour board) - 90 mins Monday, 21 December 2015 – 11:00-12:30

Topic Immunotherapy Tumorboard Panel Grant McArthur, AU

Ignacio Melero, ES Caroline Robert, FR Alexander van Akkooi, NL

Title presentation 1 Sequencing / combination of treatments (targeted agents) Speaker 1 Grant McArthur, AU Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Toxicity of the new immunotherapies for melanoma Speaker 3 Caroline Robert, FR

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 How new drugs are changing the role of surgery in melanoma Speaker 5 Alexander van Akkooi, NL

Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience Special Symposium - 90 mins Sunday, 20 December 2015 – 14:30-16:00

Title symposium Immuno-oncology: Delivering the promise Chair Ignacio Melero, ES Co-Chair Koji Tamada, JP Title presentation 1 Introduction Speaker 1 Chair or Co-Chair Lecture time 1 5’ Title presentation 2 Development of checkpoint inhibitors for cancer therapy Speaker 2 Naoya Yamazaki, JP Lecture/disc time 2 20’ Title presentation 3 Immune profiling of tumours Speaker 3 Davide Bedognetti, QA Lecture/disc time 3 20’ Title presentation 4 Gene-modified T cell and adoptive cell therapy Speaker 4 Hiroshi Shiku, JP Lecture/disc time 4 20’ Title presentation 5 Clinical perspectives and conclusions Speaker 5 Peter Hersey, AU Lecture/disc time 5 20’ Title presentation 6 Q&A Speaker 6 Chair or Co-Chair Lecture/disc time 6 5’

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Sarcoma Chair: Jean-Yves Blay, FR Scientific committee members: Paolo G. Casali, IT Ian Judson, UK Javier Martin-Broto, ES Akira Kawai, Jp Desen Wan, CN Educational session – 90 mins Sunday, 20 December 2015 – 11:00–12:30

Title Management of soft tissue sarcomas Chair Javier Martin-Broto, ES Co-Chair To be announced Title presentation 1 The role of guidelines in improving patient care in STS

(how do they help, what intended for, how to applied for benefit of pts) Speaker 1 Akira Kawai, JP Lecture/disc time 1 30’ Title presentation 2 State-of-the-art in local disease Speaker 2 Javier Martin-Broto, ES Lecture time 2 30’ Title presentation 3 State-of-the-art in metastatic disease Speaker 3 Axel Le Cesne, FR Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Monday, 21 December 2015 – 08:00-08:45

Title Exceptions for standard medical treatments in STS Speaker Paolo G. Casali, IT Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience

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Patient cases (tumour board) - 90 mins Saturday, 19 December 2015 – 14:30-16:00

Topic Difficult cases in sarcoma Tumorboard Panel Jayesh Desai, AU

Marco Fiore , IT Tadashi Kamada, JP

Title presentation 1 A rare histological subtype: Epithelioid sarcoma, or ASPS? Speaker 1 Jayesh Desai, AU Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Pannelists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Surgery of metastastic sarcoma Speaker 3 Marco Fiore , IT Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Pannelists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 New radiotherapy techniques for complex presentations Speaker 5 Tadashi Kamada, JP Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Pannelists Lecture/disc time Maximum 15’ discussion time with audience Special Symposium - 90 mins Monday, 21 December 2015 – 09:00-10:30

Title symposium How does biology guide the treatment of sarcoma? Chair Akira Kawai, JP Co-Chair To be announced Title presentation 1 Introduction Speaker 1 Akira Kawai, JP Lecture time 1 5’ Title presentation 2 Soft tissue sarcoma Speaker 2 Richard Quek, SG Lecture/disc time 2 20’ Title presentation 3 GIST Speaker 3 Toshiro Nishida, JP Lecture/disc time 3 20’ Title presentation 4 Bone sarcoma Speaker 4 Paolo dei Tos, IT Lecture/disc time 4 20’ Title presentation 5 The emerging role of immunology in sarcoma Speaker 5 Jean-Yves Blay, FR Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Co-Chair Lecture/disc time 6 5’

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Supportive & palliative care Chair: Mario Dicato, LU Scientific committee members: Matti Aapro, CH Yeur-Hur Lai, TW Florian Scotte, FR Alex Molassiotis, CN Dorothy Keefe, AU Educational session – 90 mins Sunday, 20 December 2015 – 11:00–12:30

Title Supportive and palliative care: Tips for your daily practice Chair Mario Dicato, LU Co-Chair To be announced Title presentation 1 Pain management Speaker 1 Seiji Hattori, JP Lecture/disc time 1 30’ Title presentation 2 Venous thromboembolic issues (including novel oral anticoagulants) Speaker 2 Mario Dicato, LU Lecture time 2 30’ Title presentation 3 Targeted therapy related mouth toxicities Speaker 3 Dorothy Keefe, AU Lecture/disc time 3 30’ Challenge Your Expert session - 45 mins Monday, 21 December 2015 – 08:00-08:45

Title Managing skin toxicity from targeted agents Speaker Caroline Robert, FR Lecture/disc time 3 Presentation maximum 30’.

15’ Discussion time with audience

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Patient cases (tumour board) - 90 mins Sunday, 20 December 2015 – 14:30-16:00

Topic A patient with breast cancer, depressed and with active hepatitis B, has an indication for chemo followed by aromatase inhibitors

Tumorboard Panel Matti Aapro, CH Takashi Ishikawa, JP John Lubel, AU Jane Turner, AU

Title presentation 1 Bone Speaker 1 Takashi Ishikawa, JP Lecture/disc time Maximum 15’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 3 Hepatitis

Speaker 3 John Lubel, AU

Lecture/disc time Maximum 15’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 15’ discussion time with audience Title presentation 5 Fear of cancer recurrence/progression (Speaker to give guidance for the daily practice) Speaker 5 Jane Turner, AU

Lecture/disc time Maximum 15’ Title presentation 6 Tumour board discussion Speaker 6 Panellists Lecture/disc time Maximum 15’ discussion time with audience Special Symposium - 90 mins Monday, 21 December 2015 – 11:00-12:30

Title symposium Assuring that the treatment is acceptable: Managing side-effects in practice Chair Alex Molassiotis, CN Co-Chair To be announced Title presentation 1 Introduction Speaker 1 Alex Molassiotis, CN Lecture time 1 5’ Title presentation 2 Cardiac toxicities Speaker 2 Thomas Suter, CH Lecture/disc time 2 20’ Title presentation 3 Nutrition / cachexia / anorexia

(to include local values of food and eating / cultural importance) Speaker 3 Jeya Henry, SG Lecture/disc time 3 20’ Title presentation 4 Anti-emetics Speaker 4 Matti Aapro, CH Lecture/disc time 4 20’ Title presentation 5 Peripheral neuropathy Speaker 5 Alex Molassiotis, CN Lecture/disc time 5 20’ Title presentation 6 Conclusions and (clinical) perspectives Speaker 6 Co-Chair Lecture/disc time 6 5’

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Thoracic cancers Chair: Yi Long Wu, CN Scientific committee members: Pasi Jånne, US Tetsuya Mitsudomi, JP Keunchil Park, KP Solange Peters, CH Sumitra Thongprasert, TH Martin Reck, DE Educational session 1 – 90 mins Friday, 18 December 2015 – 16:30-18:00

Title New challenges in immunotherapy for lung cancer Chair Yi-Long Wu, CN Co-Chair To be announced Title presentation 1 The place of immune check point inhibitors in NSCLC Speaker 1 Solange Peters, CH Lecture/disc time 1 30’ Title presentation 2 Challenges of biomarkers and patients selection Speaker 2 Martin Reck, DE Lecture time 2 30’ Title presentation 3 Management of toxicities and perspectives Speaker 3 Ross Soo, SG Lecture/disc time 3 30’ Educational session 2 – 90 mins Monday, 21 December 2015 – 11:00-12:30

Title Optimal therapy for earlier stages of NSCLC Chair Tetsuya Mitsudomi, JP Co-Chair Johan Vansteenkiste, BE Title presentation 1 Optimal treatment of potentially resectable stage IIIA/N2 disease Speaker 1 Tetsuya Mitsudomi, JP Lecture/disc time 1 30’ Title presentation 2 Optimal adjuvant treatment for resected NSCLC Speaker 2 Yi-Long Wu, CN Lecture time 2 30’ Title presentation 3 Oligometastatic disease Speaker 3 Suresh Senan, NL Lecture/disc time 3 30’

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Challenge Your Expert session - 45 mins Sunday, 20 December 2015 – 08:00 – 08:45

Title Prevention and screening in tobacco control Speaker Haseem Ashraf, NO Lecture/disc time 3 Presentation maximum 25-30’.

Minimum 20-15’ Discussion time with audience Patient cases (Tumour board) - 90 mins Monday, 21 December 2015 – 09:00-10:30

Topic Multidisciplinary management of locally advanced thoracic malignancies Tumorboard Panel Ken O’Byrne, AU

You Lu, CN Keunchil Park, KR Paul Van Schil, BE

Title presentation 1 Mesothelioma Speaker 1 Ken O’Byrne, AU Lecture/disc time Maximum 20’ Title presentation 2 Tumour board discussion Speaker 2 Panellists Lecture/disc time Maximum 25’ discussion time with audience Title presentation 3 Stage III NSCLC with EGFR mutation Speaker 3 Keunchil Park, KR

Lecture/disc time Maximum 20’ Title presentation 4 Tumour board discussion Speaker 4 Panellists Lecture/disc time Maximum 25’ discussion time with audience Special Symposium - 90 mins Saturday, 19 December 2015 – 11:00–12:30

Title symposium Oncogene addicted NSCLC Chair Daniel Tan, SG Co-Chair Pasi Jånne, US Title presentation 1 Introduction Speaker 1 Daniel Tan, SG Lecture time 1 5’ Title presentation 2 Diagnosis and monitoring of oncogene addicted cancers Speaker 2 Qing Zhou, CN Lecture/disc time 2 20’ Title presentation 3 ALK management and resistance Speaker 3 Kazuhiko Nakagawa, JP Lecture/disc time 3 20’ Title presentation 4 EGFR management and resistance Speaker 4 Pasi Jånne, US Lecture/disc time 4 20’ Title presentation 5 Targeting signal transduction pathways Speaker 5 Egbert Smit, NL Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Pasi Jånne, US Lecture/disc time 6 5’

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Best of 2015 Congress Highlights Session 1 – The best of 2015 Monday, 21 December 2015 – 14:00-15:30 Chair(s): TBC

14:30 Breast cancer Fabrice André, FR 14:45 Sarcoma Paolo Casali, IT 15:00 Melanoma & immunotherapy Ignacio Melero, ES 15:15 Gynaecological cancers Andrés Cervantes, ES 15:30 CNS tumours Michael Weller, CH 15:45 Head & Neck cancer Jean-Pascal Machiels, BE

Congress Highlights Session 2 – The best of 2015 Monday, 21 December 2015 – 14:00-15:30 Chair(s): TBC

14:30 Thoracic cancers Caicun Zhou, CN 14:45 Supportive & palliative care Florian Scotté, FR 15:00 Haematological malignancies Michele Ghielmini, CH 15:15 Developmental therapeutics Tony S.K. Mok, CN 15:30 Genitourinary tumours Joaquim Bellmunt, US 15:45 Gastrointestinal tumours Eric Van Cutsem, BE

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Special sessions Special Session - 90 mins Friday, 18 December 2015 – 16:30-18:00

Title symposium Geriatric oncology in Asia Chair Matti Aapro, CH Co-Chair Ravindran Kanesvaran, SG Title presentation 1 Aging population in Asia and cancer Speaker 1 Ravindran Kanesvaran, SG Lecture time 1 20’ Title presentation 2 Evaluating the aging patient: SIOG proposals Speaker 2 Matti Aapro, CH Lecture/disc time 2 20’ Title presentation 3 The Korean model Speaker 3 Jee Hyun Kim, KR Lecture/disc time 3 20’ Title presentation 4 The Japanese experience Speaker 4 Fumio Nagashima, JP Lecture/disc time 4 20’ Title presentation 5 Panel discussion: Case discussions on adapting patient care to the issues of aging cancer patients Speaker 5 To be announced Lecture/disc time 5 10’ Special Session - 90 mins Sunday, 20 December 2015 – 09:00–10:30

Title symposium Rare cancers: Improving by networking in Asia and Europe Chair Akira Kawai, JP Co-Chair Jean-Yves Blay, FR Title presentation 1 Introduction Speaker 1 Jean-Yves Blay, FR Lecture time 1 5’ Title presentation 2 Rare Cancers Europe Consensus on the pathologic diagnosis of rare cancers Speaker 2 A. Paolo Dei Tos, IT Lecture/disc time 2 20’ + 5’ discussion Title presentation 4 Rare Cancers Europe Consensus on the methodology of research in rare cancers Speaker 4 Paolo G. Casali, IT Lecture/disc time 4 20’ + 5’ discussion Title presentation 5 Improving networking on rare cancers in Asia Speaker 5 Akira Kawai, JP Lecture/disc time 5 20’ + 5’ discussion Title presentation 6 Conclusions Speaker 6 Jean-Yves Blay, FR Lecture/disc time 6 10’

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Special Session - 90 mins Sunday, 20 December 2015 – 11:00–12:30

Title symposium Resource constraints as a barrier to lung cancer management: Developing nations Chair Sumitra Thongprasert, TH Co-Chair Alex Eniu, RO Title presentation 1 Resource constraints in developing countries (include session introduction) Speaker 1 Sumitra Thongprasert, TH Lecture time 1 15’ Title presentation 2 The ESMO Magnitude of Clinical Benefit Scale (with focus on the methodology which constitutes

the MCBS background) Speaker 2 Christoph Zielinski, AT Lecture/disc time 2 15’ Title presentation 3 How relevant is cost-effectiveness in different regions? Speaker 3 Unchalee Permsuwan, TH Lecture/disc time 3 15’ Title presentation 4 Assessment of resources and healthcare in Canada Speaker 4 William Evans, CA Lecture/disc time 4 15’ Title presentation 5 ESMO data on international availability of cancer medicine Speaker 5 Alex Eniu, RO Lecture/disc time 5 15’ Title presentation 6 Discussion Speaker 6 Lecture/disc time 6 15’

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Joint Symposia Joint Symposium 1 - 90 mins Saturday, 19 December 2015 – 11:00 – 12:30

Title symposium ESMO-CSCO-JSMO-KACO Joint Symposium Clinical research in gastric and lung cancers

Chair Rolf A. Stahel, CH Co-Chair(s) To be announced Title presentation 1 Introduction Speaker 1 Co-Chair Lecture time 1 5’ Title presentation 2 Academic clinical lung cancer research in Europe Speaker 2 Rolf A. Stahel, CH Lecture/disc time 2 20’ Title presentation 3 Clinical research in lung cancer in Japan Speaker 3 Yuichiro Ohe, JP Lecture/disc time 3 20’ Title presentation 4 Current development of palliative treatment of gastric cancer Speaker 4 Jin Li, CN Lecture/disc time 4 20’ Title presentation 5 Asian gastric cancer Speaker 5 Hyun Cheol Chung, KR Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Rolf A. Stahel, CH Lecture/disc time 6 5’

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Joint Symposium 2 - 90 mins Saturday, 19 December 2015 – 14:30 – 16:00

Title symposium ESMO-SSO-MOGA-ISMPO Joint Symposium Asia-Pacific perspectives: Emerging issues in oncology

Chair Fortunato Ciardiello, IT Co-Chair(s) Ravindran Kanesvaran, SG Title presentation 1 Introduction Speaker 1 Ravindran Kanesvaran, SG Lecture time 1 5’ Title presentation 2 TBC Speaker 2 Fortunato Ciardiello, IT Lecture/disc time 2 20’ Title presentation 3 Emerging oncology issues: The Singapore Perspective Speaker 3 Ravindran Kanesvaran, SG Lecture/disc time 3 20’ Title presentation 4 Emerging issues in Australian cancer care, management and research

(Overview of the range of issues that are prominent and coming to the fore in Australian oncology from workforce issues, the funding of high costs drugs and survivorship through to research directions, and emerging trends in cancer types and clinical practice)

Speaker 4 Rosemary Harrup, AU Lecture/disc time 4 20’ Title presentation 5 Getting prepared for the cancer tsunami with the grey tsunami Speaker 5 Gouri Bhattacharyya, IN Lecture/disc time 5 20’ Title presentation 6 Conclusions and clinical perspectives Speaker 6 Fortunato Ciardiello, IT Lecture/disc time 6 5’

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ESMO Clinical Practice Guideline Sessions Saturday, 19 December 2015 - 09:00-10:30

ESMO Clinical Practice Guidelines 1 Chair: Kei Muro, JP Co-Chair: Andrés Cervantes, Valencia, Spain

09:00 Introduction to the ESMO Clinical Practice Guidelines sessions Kei Muro, JP

09:10 Questionnaire Andrés Cervantes, ES

09:15 09:25

Ovarian cancer case presentation Speaker: Jonathan Ledermann, UK Discussant: Keiichi Fujiwara, JP

09:35 Questions and answers 09:40 09:50

Cancer of unknown primary (CUP) case presentation Speaker: George Pentheroudakis, GR Discussant: Linda Mileshkin, AU

10:00 Questions and answers 10:05 10:15

Gastric cancer case presentation Speaker: Dirk Arnold, DE Discussant: Yung-Jue Bang, KR

10:25 Questions and answers Sunday, 20 December 2015 - 09:00-10:30

ESMO Clinical Practice Guidelines 2 Chair: Qing Zhou, CN Co-Chair: George Pentheroudakis, GR

09:00 Introduction to the ESMO Clinical Practice Guidelines sessions Qing Zhou, CN

09:10 Questionnaire George Pentheroudakis, GR

09:15 09:25

Breast cancer case presentation Speaker: Fatima Cardoso, PT Discussant: Rebecca Dent, SG

09:35 Questions and answers 09:40 09:50

Diffuse large B-cell lymphoma case presentation Speaker: Michele Ghielmini, CH Discussant: Constantine Tam, AU

10:00 Questions and answers 10:05 10:15

Colon cancer case presentation Speaker: Dirk Arnold, DE Discussant: Jin Li, CN

10:25 Questions and answers

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Monday, 21 December 2015 - 09:00-10:30

ESMO Clinical Practice Guidelines 3 Chair: Sung Bae Kim, KR Co-Chair: George Pentheroudakis, GR

09:00 Introduction to the ESMO Clinical Practice Guidelines sessions Sung-Bae Kim, KR

09:10 Questionnaire George Pentheroudakis, GR

09:15 09:25

Lung cancer (early disease, EGFR status) case presentation Speaker: Keith Kerr, UK Discussant: Tetsuya Mitsudomi, JP

09:35 Questions and answers 09:40 09:50

Cancer pain & breathlessness, dyspnoea case presentation Speaker: Florian Scotté, FR Discussant: Seiji Hattori, JP

10:00 Questions and answers 10:05 10:15

Prostate cancer case presentation Speaker: Alan Horwich, UK Discussant: Kim Chi, BC, CA

10:25 Questions and answers