Focused on Biologics

Comprehensive Product Guide for Bone Graft Substitutes and Soft-Tissue Repair

GRAFTJACKET NOW™

Regenerative Tissue Matrix

PRO-DENSE™

Injectable Regenerative Graft

ACTISHIELD™

Amniotic Barrier Membranes

FUSIONFLEX™

Demineralized Moldable Scaffold

ALLOPURE™

Allograft Wedges

IGNITE™ POWER MIXInjectable Stimulus

AUGMENT® Bone Graft

Ordering InformationRecombinant Human Growth Factor TechnologyAUGMENT®Bone Graft K20001510 1.5cc K20003010 3.0cc

AUGMENT®Injectable K30003010 3.0cc K30001510 1.5cc

Bone Repair Products

OSTEOSET™

Resorbable Bead Kit bead molds included

Fast Cure 84000611 5.0cc (3.0 or 4.8mm beads) 84000311 25cc (7mm beads)

Standard Cure 84000511 5.0cc (3.0 or 4.8mm beads) 84000211 25cc (7mm beads)

DBM PUTTIES ALLOMATRIX™ Injectable Putty 86000100 1.0cc 86000500 5.0cc 86001000 10cc

ALLOMATRIX™ Bone Putty with 1-4mm cancellous chips 86DR0300 3.0cc 860C0500 5.0cc 860C1000 10cc

ALLOMATRIX™ Custom with 4-7mm cancellous chips 86XC0500 5.0cc 86XC1000 10cc

TENSIX™ DBM and Crush-MixPre-Hydrated Putties PHG-01P TENSIX DBM Putty 1.0cc PHG-02C TENSIX DBM Crush Mix 2.5cc PHG-02P TENSIX DBM Putty 2.5cc PHG-05C TENSIX DBM Crush Mix 5.0cc PHG-05P TENSIX DBM Putty 5.0cc PHG-10C TENSIX DBM Crush Mix 10cc PHG-10P TENSIX DBM Putty 10cc

INJECTABLE SETTABLE

PRO-DENSE™

Injectable Regenerative Graft87SR0020 2cc 87SR0050 5cc 87SR0070 7cc 87SR0100 10cc 87SR0120 12cc 87SR0150 15cc 87SR0400 40cc

Core Decompression Procedure Kit 87SRCDK0 15cc

PRO-STIM™

Injectable Inductive Graft 86SR0404 (EXTREMITY) 4cc 86SR0410 10cc 86SR0420 20cc

Core Decompression Procedure Kit 86SRCK15 15cc

DISPOSABLE AND REUSABLE INSTRUMENTS1000KIT2 X-REAM™ Percutaneous Expandable Reamer 20BL1200 X-REAM Expandable Reamer Blade 84LK0000 Osteolysis Procedure Kit PSCL0000 Extremity Procedure Kit 1200BMAK PROGRESS™ Bone Marrow Aspiration Kit

Refer to product package inserts for prescribing information, including indications, risks, and precautions.

FLEXIBLE SCAFFOLDS

FUSIONFLEX™ Demineralized Moldable Scaffold 86082020 20x20x4mm 86082040 20x20x4mm (2/pkg) 86082050 20x50x4mm

ALLOGRAFT WEDGES ALLOPURE™ Bicortical Wedges 86660006 6.0mm Bicortical Wedge 86LL0006 6.0mm Bicortical Wedge

86660800 8.0mm Bicortical Wedge 86LL0800 8.0mm Bicortical Wedge

86661000 10mm Bicortical Wedge 86LL1000 10mm Bicortical Wedge

86661200 12mm Bicortical Wedge 86LL1200 12mm Bicortical Wedge

Tricortical Blocks OP101020 Small Tricortical Block OP101022 Medium Tricortical Block OP101024 Large Tricortical Block

INJECTABLE STIMULUS IGNITE™ Injectable Repair Graft 876P0040 4.0cc876P0080 8.0cc876P0200 20cc

Soft-Tissue Graft ProductsACTISHIELD™ Amniotic Barrier MembraneChorion-based, ThickAM202X04 2x4cmAM204X04 4x4cmAM204X08 4x8cm

ACTISHIELD™ CF Amniotic Barrier Membrane Chorion Free, ThinAM452X04 2x4cmAM454X04 4x4cmAM454X08 4x8cm

VIAFLOW™ Flowable Placental Tissue Matrix AMAF0005 0.5cc AMAF0010 1.0cc AMAF0020 2.0cc

VIAFLOW™ C Cryopreserved Flowable Placental Tissue Matrix AMCF0010 1.0cc

GRAFTJACKET NOW™ Regenerative Tissue Matrix

Thin 86102X04 2x4cm 86104X04 4x4cm 86104X08 4x8cm

Standard 86202X12 2x12cm 86202X04 2x4cm 86204X04 4x4cm 86204X08 4x8cm

Thick 86304X04 4x4cm 86304X08 4x8cm

Wound Care ProductsBIOSKIN® Amniotic Wound Matrix WA204X04 4x4cm WA202X04 2x4cm WA202X03 2x3cm WA202X02 2x2cm WA20D015 DISC 15mm

AP-007295C_29-Oct-2019

™ and ® denote Trademarks and Registered Trademarks of Wright Medical Group N.V. or its affiliates. ©2019 Wright Medical Group N.V. or its affiliates. All Rights Reserved.

BioMimetic Therapeutics, LLC389 Nichol Mill LaneFranklin, TN 37067877 670 2684615 236 4527

1023 Cherry Road Memphis, TN 38117 800 238 7117 901 867 9971 www.wright.com

56 Kingston RoadStaines-upon-ThamesSurrey TW18 4NLUnited Kingdom+44 (0)845 833 4435

161 Rue Lavoisier38330 Montbonnot Saint MartinFrance+33 (0)4 76 61 35 00

AUGMENT® Injectable

BIOSKIN®

Amniotic Wound Matrix

Focused on Biologics

Tendon / Ligament ReinforcementGRAFTJACKET NOW™

Regenerative Tissue MatrixGRAFTJACKET NOW™ Regenerative Tissue Matrix is a human dermal tissue graft with excellent mechanical properties for augmentation and reinforcement applications. GRAFTJACKET NOW™ Matrix provides a scaffold for repair and comes pre-hydrated and is intuitive to use in the OR.

OsteotomiesALLOPURE™

Allograft WedgesALLOPURE™ Allograft Bone Wedges provide foot and ankle surgeons the simplicity of pulling ready-to-use, sterile allograft off the shelf for open wedge osteotomies.

Accelerated Healing*

PRO-STIM™

Injectable Inductive GraftPRO-STIM™ Graft is the next step in composite grafting technology. Built on the PRO-DENSE™ material platform as a combination of calcium sulfate and calcium phosphate, PRO-STIM™ Graft adds demineralized bone matrix (DBM) for osteoinductive factors to speed the healing and remodeling process.*Data based on canine proximal humerus model. Accelerated healing compared to autograft and bone remodeling to normal bone at 13 weeks —it is unknown how results from the canine model compared with clinical results in humans.

Injectable StimulusIGNITE™

Injectable GraftIGNITE™ Graft contains osteoinductive DBM and may be combined with the osteogenic potential of autologous bone marrow aspirate. The resulting bio-composite provides an injectable stimulus with osteogenic potential.

DBM That Stays In PlaceALLOMATRIX™

DBM Composite GraftALLOMATRIX™ Graft is a combination of surgical-grade calcium sulfate, demineralized bone matrix (86% by volume), and small cancellous chips. This composition results in an osteoinductive biocomposite providing desired handling characteristics and fluid resilience. This DBM putty is provided in a powdered form to preserve the bone morphogenic protein (BMP) activity until the point of use and facilitate its 5-year shelf life.

Dense Bone Regeneration*

PRO-DENSE™

Injectable Regenerative GraftPRO-DENSE™ Graft is a combination of calcium sulfate and calcium phosphate engineered for controlled resorption coinciding with strong, dense bone regeneration, followed by remodeling to normal bone.* Graft application can be minimally invasive and the material sets hard.*As compared to autograft. All claims based on a critically sized canine proximal humerus defect model. It is unknown how results from the canine model compare with clinical results in humans.

Amniotic and Placental TissueACTISHIELD™

Amniotic Barrier MembranesACTISHIELD™ and ACTISHIELD™ CF Amniotic Barrier Membranes are biologic allografts derived from dehydrated human amniotic tissue. ACTISHIELD™

and ACTISHIELD™ CF Membranes are sterilized post packaging.

VIAFLOW™

Flowable Placental Tissue MatricesVIAFLOW™ & VIAFLOW™ C Flowable Placental Tissue Matrices are unique, pre-mixed, tissue matrix allografts, processed from human placental tissues. This tissue matrix is sterilized post packaging.

Wound CareBIOSKIN®

Amniotic Wound MatrixBIOSKIN® is Wright’s amniotic wound matrix that provides comprehensive preservation of native amniotic tissue proteins to deliver a biologic scaffold to support clinical efforts for challenging wound treatment and accommodate covering and protecting both acute and chronic wounds.

Recombinant Human Growth Factor TechnologyAUGMENT®Regenerative SolutionsAUGMENT® Regenerative Solutions are the first and only proven alternative to autograft in hindfoot and ankle arthrodesis. AUGMENT® was proven as a safe and effective alternative to autograft, in the largest foot & ankle clinical trial in history. AUGMENT® was proven as a safe and effective alternative to autograft, in the largest foot & ankle clinical trial in history. AUGMENT® was also shown to eliminate the cost and morbidity of harvesting autograft, while providing equivalent improvements in clinical outcomes.

Bone VoidsOSTEOSET™

Resorbable Mini-Bead KitOSTEOSET™ Resorbable Mini-Bead Kit is a customizable bead kit comprised of surgical grade calcium sulfate. This resorbable graft is easily prepared in the O.R. allowing maximum surgical flexibility.