Reactions 1490, p29 - 1 Mar 2014

SOrnidazole

Acute hepatotoxicity in an elderly patient: casereport

A 65-year-old woman presented with weakness and nausea.Five days earlier, she had been prescribed ornidazole 500mgtwice daily [route not stated] for 3 days for gastro-enteritis.Tests upon current admission showed an ALT level of 304 U/L,an AST level of 310 U/L, an ALP level of 84 U/L and a GGT levelof 109 U/L. Subsequently, her symptoms and abnormal liverfunction test results completely resolved. At a follow-up on thetenth day, she had an ALT level of 32 U/L, an AST level of29 U/L and a GGT level of 52 U/L.

Author comment: "[W]e describe a rare case of acutehepatotoxicity due to the short-term use of ornidazole".Coskun Y, et al. Ornidazole induced acute hepatotoxicity in an elderly patient.European Geriatric Medicine 4: 353, No. 5, Nov 2013. Available from: URL: http://doi.org/10.1016/j.eurger.2013.07.006 - Turkey 803099789

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Reactions 1 Mar 2014 No. 14900114-9954/14/1490-0001/$14.95 Adis © 2014 Springer International Publishing AG. All rights reserved