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8/9/2019 OVCMT, AP3- lec. 6
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Kidney anatomyKidney anatomy-- reviewreview
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Nephron anatomyNephron anatomy-- reviewreview
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Urine formationUrine formation-- overviewoverview
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GlomerulusGlomerulus
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Net filtration pressueNet filtration pressue
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GFR regulationGFR regulation-- autoregulationautoregulation
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GFR regulationGFR regulation-- hormonalhormonal
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GFR regulationGFR regulation-- neuralneural
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Tubular reabsorptionTubular reabsorption-- blood vesselsblood vessels
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Tubular reabsorptionTubular reabsorption-- PCTPCT
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Tubular reabsorptionTubular reabsorption-- PCTPCT
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Tubular reabsorptionTubular reabsorption-- loop of Henleloop of Henle
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Tubular reabsorptionTubular reabsorption-- DCT and CDDCT and CD
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Tubular secretion of KTubular secretion of K++-- CDCD
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Tubular secretion of HTubular secretion of H++-- PCTPCT
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Body fluid compartmentsBody fluid compartments
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Water gain and lossWater gain and loss
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Mechanism of dehydration stimulationMechanism of dehydration stimulation
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ElectrolytesElectrolytes
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pH scalepH scale
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Maintaining pHMaintaining pH-- renal excretion of Hrenal excretion of H++
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Maintaining pHMaintaining pH-- buffer systemsbuffer systems
CO2 + H2O H2CO3 HCO3- + H+
leftward shift causes CO2 and H2O to be exhaled
rightward shift causes H+ to be buffered by bicarbonate ion and
secreted by the kidney
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Metabolic acidosis and respiratory compensationMetabolic acidosis and respiratory compensation
changes in ventilation compensate for
metabolic induced pH disturbance
changes in kidney secretion of H+ and
reabsorption of HCO3- compensate for
respiratory induced pH disturbances