Overview of

Neurocognitive and

Behavioral AssessmentsSarah N. Mattson, Ph.D.San Diego State University

Outline of Presentation

Overview of assessments General ability measures Social and communication behavior Behavior ratings

Findings from previous assessments

General Ability Measures

Bayley-III: Bayley Scales of Infant and Toddler Development-third edition Ages: 1 to 42 months Administration time: 45-60 minutes

DAS-II: Differential Abilities Scale-second edition Ages: 2:6 to 17:11 years Administration time: ~45 minutes

WAIS-IV: Wechsler Adult Intelligence Scale-fourth edition Ages: 16:0 to 90:11 years Administration time: ~60 minutes

Social and Communication Behavior

ADOS: Autism Diagnostic Observation Schedule Description: a semi-structured assessment used

to evaluate social and communication behavior across developmental levels and ages

Ages: toddlers to adults Administration time: 30-45 minutes

Behavior Ratings

VABS-II: Vineland Adaptive Behavior Scale-second edition Questionnaire and interview format Assesses adaptive behavior (personal and social skills

needed for daily living)

SCQ: Social Communication Questionnaire Assesses communication skills and social functioning

CBCL: Child Behavior Checklist Assesses adaptive and maladaptive behavioral functioning

DBD: Disruptive Behavior Disorder Rating Scale Assesses disruptive behaviors like those seen in ADHD

Research Involvement

Location: San Diego State University

Direct assessment ~2 hours to complete assessments

Parent assessment ~1-2 hours to complete questionnaires ~1 hour to complete interview at CBT

Compensation: ~ $20 financial incentive and feedback from testing

Previously Reported

Delayed development, including motor and speech

Mild to severe intellectual disabilities

Learning difficulties

Behavior Problems including compulsive behavior, short attention span, distractibility

Results from Ongoing Research

Parent and Child Questionnaire Medical Issues Developmental Milestones School & Behavior

Behavior Ratings

Relation to Deletion Size

Medical IssuesN %

Heart Problems 22 75.9%

Heart Surgery 7 24.1%

Blood Problems 25 86.2%

Ever Hospitalized 22 75.9%

CT Scan or MRI of Brain 21 72.4%

Seizures 4 13.8%

Current Meds 20 69.0%

Feeding or Eating Problems 22 75.9%

Gastrointestinal Problems 20 69.0%

Recurring Infections 21 72.4%

Hearing Problems 19 65.5%

Vision Problems 24 82.8%

Data from 2006/2008, N = 29

Developmental Milestones

Typical Development

Age in Months MN

(SD)

“Not Yet” N

(%)Crawl 9 17.96 (8.13) 1 (2.9%)

Eat solid foods 6 17.72 (13.18) 0 (0.0%)

Sit up without support 9 13.45 (5.86) 0 (0.0%)

Say first word 12 25.30 (11.95) 0 (0.0%)

Walk 12-18 28.84 (15.13) 1 (2.9%)Stay dry during the day 24 48.71 (20.22) 7 (20.0%)

Data from 2006/2008, N = 35

School & Behavior

N %

Attends School 27 93.1%

Special Education 26 89.7%

Repeated Grade 5 17.2%

Other Special Services 27 93.1%

Any Behavior Problems 21 72.4%

Dx ADHD 12 41.4%

Dx Learning Disability 15 51.7%

Data from 2006/2008, N = 29

Behavioral Functioning

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Behavioral Functioning

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JSDS

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Deletion Size & IQ

7 8 9 10 11 12 13 14 15 16 1740455055606570758085

Deletion

IQ E

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r = -.83

Deletion Size & Adaptive Behavior

7 8 9 10 11 12 13 14 15 16 1740

50

60

70

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90

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Deletion

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r = -.58

Deletion Size & Behavior

7 8 9 10 11 12 13 14 15 16 1740

50

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Deletion

CB

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r = -.71

Summary So Far…

Behavioral assessments support previous reports and may be unique from other developmental conditions

Understanding the relation between deletion size and cognition and behavior will provide important information that will help families, especially those with new diagnoses

Plans for the Future

Further examine our existing data and continue to collect new information

Seek external funding for research activities

THANK YOU!

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