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OviGen – the outputs
Áine O’ Brien1, Nóirín McHugh1, Eamon Wall2, Kevin McDermott2, Donagh Berry1
1Teagasc, Moorepark; 2Sheep Ireland, Bandon
OviGen objective
+
Parentage
Genomic predictions
Dagginess
Health traits
Lameness• No = not lame• Yes = any sign of lameness
Mastitis• No = no evidence of mastitis• Yes = evidence of (historic)
mastitis
Sire prevalence - dagginess
0
5
10
15
20
25
30
35
40
0 5 10 15 20 25 30 35 40 45 50 55 60 65 70 75
Nu
mb
er
of
Sire
s
Prevalence (%)
0
5
10
15
20
25
30
0 5 10 15 20 25 30 35 40 45
Nu
mb
er
of
sire
s
Prevalence (%)
Sire prevalence - lameness
Ewes only
Trait Economic value Relative emphasis (%)
Terminal Replacement
Dagginess -€0.34 (score) 1.15 0.17
Lameness – lamb -€0.08 (%) 0.11 0.02
Lameness - ewe -€0.24 (%) 0.04
Health index
€1.2010% 5%100 ewes
Elsewhere…
Worm FECFacial Eczema
Dagginess
Worm FECWorm FEC
LamenessDagginess
Reducing the cost of genotyping
15,000 – 50,000 DNA variants
50,000 DNA variants = €62.5015,000 DNA variants = €26.50
Currently €24.50 for 50,000 DNA variants
Other genotyping technologies?
Aim: reduce the density of the panel without compromising genotype quality
Conclusion: at least 6,000 DNA variants
required
Imputation
Breed composition
Am I really a Texel?
50% CL : 25% CV : 25% SU
50% CL : 50% SU : 0% SU
50% CL : 0% CV : 50% SU
100% Suffolk
?
100% Cheviot
50% Cheviot 50% Suffolk 100% Charollais
DNA breed compositionAm I really a
Texel?
50% Cheviot 50% Suffolk 100% Charollais
50% Charollais13% Cheviot37% Suffolk
Yes, 97% Texel
• Non consistent across all traits
• Main issue – size of reference population
Genomic predictions
Lots of data –genotypes and
phenotypesYounger animals
OviGen achievements
Health index
