P16081: SYSTEMIC CIRCULATION MODELSUBSYSTEM DESIGN REVIEW

John RayFabian PerezRobert Kelley

Mallory LennonJacob Zaremski

Our goals for this review Updates from Phase II Review (10 minutes)

CAD Schematic Analysis Subsystem Analysis (25 minutes)

Risk Analysis (5 minutes) Bill of Materials (BoM) (5 minutes) Project Plans (5 minutes)

Agenda

Goals

1. Introduce progress in engineering analysis

2. Address budget concerns

3. Demonstrate efforts to design for modification

4. Receive feedback

5. Create action plan

Finalized Objective

Our goal is to deliver a functioning physical model of systemic circulation which, when

used in conjunction with P16080’s heart pump, will be used as a teaching tool, allowing

students to validate mathematical models of the circulatory system from Chapter 5 of

“Quantitative Human Physiology” An Introduction by Joseph Feher. The model will

ultimately enhance students' understanding of the circulatory system by enabling

them to analyze the circulatory system under normal, exercise, and pathological conditions

through the measurement of pressure and flow.

Updated Use Case

ER Metrics of Quality (1 of 3)

ER Metrics of Quality (2 of 3)

ER Metrics of Quality (3 of 3)

ER mapping to F.D. (1 of 2)

ER mapping to F.D. (2 of 2)

Functional Decomposition

Morph Chart (1 of 3)

Morph Chart (2 of 3)

Morph Chart (3 of 3)

Undecided Concepts

Pressure• PASCO versus Honeywell

• LabVIEW versus DataStudio

Resistance• External Clamp vs. Valve

Updated System Architecture

CAD Schematic

Main Components

Barb tube fitting: cheapest, easiest

connection

Pressure release value: easy release valve

Drill and screw into acrylic

Ball pump: cheapest,

easiest way to add air pressure

Pressure tap into tubing

Pressure, PA

Pressure, PC Pressure, PV v

P16081 Pump

Arterial Compliance,

CA

VenousCompliance,

CV

Flow

Resistance

1

2

345

LabVIEW

6

7 8 9

Subsystems Agenda

1 & 5 - Pressure

2 & 4 - Compliance

3 - Resistance

6 - Labview

7, 8 & 9 - Consult with P16080

Pressure Sensor Analysis1. Flow Diagram

2. PASCO Sensors

3. Honeywell Sensors

4. Bill of Materials

5. Test Plan

6. Risks

Pressure Flow Diagram

Analog Pressure Signal

Digital Pressure Signal

DAQ

Amplifier Board

ComputerLabView Program

AC Power

Energy

Information

Pressure vs. Time Graph

PASCO Sensors

Will need more than one computer for real time system analysis

• LabView for heart, DataStudio for circulatory pressures

• LabView needed for automatic resistance control

Pros Cons

Already Owned No integration with LabView

Differential Pressure Capabilities

Special Pressure Taps Needed

User Friendly

http://www.pasco.com/file_downloads/product_manuals/PASPORT-Dual-Pressure-Sensor-Manual-PS-2181.pdf

Maximum Sampling Rate 1000 Hz

Absolute Pressure Range 0-1500 mmHg

Differential Pressure Range -750-750 mmHg

Resolution 0.075 mmHg at 10 Hz

Repeatability 7.5 mmHg

Tubing (Type) Polyurethane

Tubing Size (Diameter) 3.2 mm

Tubing Length 2.4 m

InterfaceData Studio (New one coming soon?)

Source:PasPort Instruction Sheet (012-09969A)

Honeywell Sensors

Only one computer program needed for both heart and circulatory

• DAQ is already provided, but would need to build the circuit board/LabView Program

http://www.mouser.com/ProductDetail/Honeywell/HSCMRNT005PGAA5/?qs=%2fha2pyFaduhkciXVz6btFHLY3u79xkDhknp39AuPvmffYIGgrGx0aQ%3d%3d

Pros Cons

Integration With LabView

More Expensive than PASCO

Accuracy Will need a Sensor Board/DAQ

Liquid Friendly

TruStability Board Mount Pressure Sensors: HSC Series (HSCMRNT005PGAA5)

Operating Gage Pressure Range 0-258 mmHg

Output Type Analog

Pressure Type Gauge

Operating Supply Voltage 5 V

Operating Temperature -40-85 C

Operating Supply Current 20 mA

Accuracy 0.25%

Liquid Media Capable? Yes

Source:

HSCMRNT005PGAA5 Datasheet (Mouser.com)

Honeywell SensorsDimensions

http://www.mouser.com/ProductDetail/Honeywell/HSCMRNT005PGAA5/?qs=%2fha2pyFaduhkciXVz6btFHLY3u79xkDhknp39AuPvmffYIGgrGx0aQ%3d%3d

Pressure BOMComponent

IDComponen

tSupplier Supplier ID Quanitity/Dimensions Price/Unit Total

CostNotes

P1 Honeywell Board Mount Pressure Sensor

Mouser Electronic

HSCMRNT005PGAA5 2 $45.78 $91.56 May only need 1 (48.85)

P2 PASCO Sensor

PASCO PS-2181 2 Free - Already Owned

P3 Pressure Taps

PASCO ME-2224 6 $16.00 $96.00 Comes as a set of 6

Might be able to borrow for free (Rep mentioned it)

Pressure Risks

5 Technical Not being able to generate required values

6 Technical Seal on the pressure tap leaks

7 Technical Not being able to calibrate within time constraints

9 Resource System components will be expensive

11 SafetyElectricity and water combination can cause

dangerous conditions

Owner: Jack

PRESSURE TEST PLAN1.Prove Sensor Functionality

a. Flow through a pipe with decreased diameter in the center

b. Pressure taps at two points

c. Measure the pressure drop

2.Calibration of the Sensors

a. Obtain a full tank of known pressure

b. Measure the pressure and correct accordingly

Subsystem - Compliance Tank1. Flow Diagram

a. Energy, Material, and Information I/O

b. Interfaces

2. Cylinder or rectangular prism?

a. Pros and cons

b. Feasibility

3. Bill of Materials (Draft)

4. Subsystem Risks

5. Preliminary Ideas for Testing Plans

Pressure

Flow

AC Power

Air Height Compliance

Pressure TransducerLabVIEW

Pressure vs. Time

Flow

Pressure

Forced Air

Energy

Material

Information

Cylindrical Tanks

ProsFewer pieces

Less interfaces to seal

ConsPrice limits diameter

Interfacing with tubing and pressure taps

Rectangular Tanks

ProsFlat surfaces easier to machine and

interface

ConsMore pieces that need to be machined

and sealed

Cylindrical Arterial Compliance Tank

2 3 4 5 6 7 8 9 10 11 120

0.5

1

1.5

2

2.5

3

3.5

4

4.5

5 Polycarbonate 5.75ID [in]

Acrylic 5ID [in]

Height (inches)

Co

mp

lia

nc

e (

mL

/mm

Hg

)

Cylindrical Venous Compliance Tank

0 5 10 15 20 250

5

10

15

20

25

30

35Acrylic 9.75ID [in]

Polycarbonate 5.75ID [in]

Height (inches)

Co

mp

lia

nc

e (

mL

/mm

Hg

)

Rectangular Arterial Compliance Tank

2 4 6 8 10 12 14 160

1

2

3

4

5

6

7

8

9

4x4x12 [in]

4x8x16 [in] (Donovan)

Height (Inches)

Co

mp

lia

nc

e (

mL

/mm

Hg

)

Rectangular Venous Compliance Tank

2 4 6 8 10 12 14 160

5

10

15

20

25

30

35

40

12x12x16 [in]12x8x16 [in] (Donovan)

Height (inches)

Co

mp

lian

ce

(m

L/m

mH

g)

Technical Risks - Compliance Tank

Resource & Safety Risks - Compliance Tank

Compliance BOM - Cylindrical

Compliance BOM - Rectangular

• 6-sided tank would be around $200

Compliance - Preliminary Testing Plans

1.Air tight seal

a. pressurize, use soap, and look for bubbles

2.Generate chart to allow students to know which height

corresponds to a desired condition - scale on box

3.Excel spreadsheet for liquid height and corresponding

compliance values

Resistance Agenda1. Flow Diagram

2. Valve and Resistance Analysis

3. Bill of Material and Alternative Bill of Materials

4. Risks

5. Test Plans

Resistance Flow

Valve and Resistance AnalysisResistance can be modeled after Ohm’s Law in that: R=ΔP/F where ΔP is

the height difference and F is the mean flow rate.

[http://circ.ahajournals.org/content/89/2/893.full.pdf]

Valve and Resistance ContinuedFor Valves resistance and friction can be modeled as:

hf=(Kv^2)/2gWhere K is the resistance coefficient, f is the Darcy

friction factor, V is the velocity and hf is the Frictional Loss or Head Loss.

Considering using a Gate valve for purposes of the design.● Resistance will have to be tested manually

○ Test each resistor position and correlate them to the pressure output seen

■ Create a graph of resistor position vs pressure output

Valve ConsiderationsOther potentials: Linear Actuator and Globe Valve

Resistance BOM

Subsystem

Component ID Component Supplier

Supplier ID

Quanitity / Dimensions Price/Unit Total Cost Notes

Valve V1

Bronze Gate Valve-Class 125, 3/4" NPT Female, Non-rising Stem

McMaster Carr 4619K14 1 $27.96 $27.96

May be alternated for linear actuator

SubsystemComponent

ID Component SupplierSupplier

IDQuanitity /

Dimensions Price/Unit Total Cost Notes

Linear Actuator LA1

25mm Diamter Actuator Exteded strew with motor

Anaheim Automation

TSFCA25-150-21-023-LW4 11 $39.00 $39.00

Can only apply 10 Newtons of Force.

Globe Valve GV

Low-Pressure Bronze Globe Valve, 3/4" NPT Female, EPDM Disc

McMaster Carr 4695K65 1 $37.44 $37.44

Meant for low pressure flows, overall length of 2 5/16”

Current BOM

Alternative BOM

Resistance Risks

Resistance - Preliminary Testing Plans1.Calibration

a. Make sure when impedance is 0 R=ΔP/F is obeyed.

b. Make sure when impedance is at max there is no flow through the

system after this point.

2.Calculate theoretical head loss through circuit and perform

head loss experiment on the pipe and valve to confirm

compliance to the theoretical model (initial set up for

MSD)

LabVIEW

LabVIEW Considerations

• Waveform consistency

• Same parameters give

same waveforms each

time

• Interfacing with pressure

sensors

• One program for both

teams

F. M. Donovan (1975) Design of a Hydraulic Analog of the Circulatory System for Evaluating Artificial Hearts, Biomaterials, Medical Devices, and Artificial Organs, 3:4, 439-449

Arterial

Venous

Preliminary Life Span Calculation

Considerations:

What will likely fail first?

Is that part expensive?

Is that part easy to replace?

New risks

Mitigated Risks

Risk Chart

Draft System Bill of Materials (1 of 2)

Draft System Bill of Materials (2 of 2)

Project Plan - what we achieved

Project Plan - deliverables for next phase

End of MSD I Deliverables1. “Working” theoretical model

2. Finalized, completed and accurately priced Bill of Materials

3. CAD drawing 100% done

4. Test plan for design 90% complete

5. Theoretical risk list complete with ideas as to how to minimize

potential effects

6. Understanding of deliverables for MSD II

7. Short list of contests this design could enter

Ways to Improve Efficiency

1. More organized direction for research of parts and

materials

2. Better collaboration with P16080

3. More organized group meetings

Goals for Phase IV

1. Choose the most efficient pressure sensor

2. Decide on dimensions for compliance tanks

3. Decide on internal versus external resistances

4. Interactions with P16080

• LabVIEW

• Flow meter

• Interfacing

ASEE 123rd Annual Conference & Exposition

• Abstract submitted on October 20th, 2015

• Abstract decision deadline: November 9, 2015