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Pathologic Responses of the Nervous System. GROSS CHANGES Finding the lesion Gross artefacts Gross lesions. HISTOLOGIC REACTIONS OF CELLS. Reactions of Neurons swelling and shrinkage. Reactions of Neurons satellitosis neuronophagia. Reactions of Neurons chromatolysis - PowerPoint PPT Presentation
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Pathologic Responses of the Nervous System
GROSS CHANGES
Finding the lesion
Gross artefacts
Gross lesions
Reactions of Neurons
neurapraxis - loss of function only
axonotmesis - damage to axons with
preservation of myelin
sheaths
neurotmesis - severance of entire nerve
fibre
Reactions of astrocytes
hyperplasia and
hypertrophy
reactive astrocytes
fibrillary
astrogliosis
gemistocytes
Reactions of oligodendrocytes hydropic swelling
hypomyelination
status spongiosus
demyelination
remyelination
Reactions of Schwann cells
wallerian degeneration and regeneration in PNS
hypomyelination and demyelination
Neoplastic Diseases
brachycephalic dogs
CNS - glial and meningeal tumours
PNS - Schwann cell tumours
secondary and axial tumours