Pediatric Immunization (EPI)

Garcia, Garzon, Gaspar, Gatchalian, Gaw, Geraldoy, Geronimo, Geronimo,

Geronimo

Vaccine Min age at 1st dose

Number of doses

Dose Minimum interval between

doses

Route Site

BCG Birth or anytime

after birth 1

0.05 mL -- Intradermal Right deltoid region of the

arm

DPT 6 weeks 3 0.05 mL 4 weeks Intramuscular Upper outer portion of the

thigh

OPV 6 weeks 3 2-3 drops

4 weeks Oral Mouth

Hep B At birth 3 0.05 mL 6 weeks interval from

1st dose to 2nd dose,8 weeks interval

from2nd dose to third

dose.

Intramuscular Upper outer portion of the

thigh

Measles 9 months 1 0.05 mL -- Subcutaneous Upper outer portion of the

arms

Expanded Program on Immunization

Bacillus Calmette-Guerin• Vaccine against tuberculosis• Attenuated live bovine tuberculosis bacillus, Mycobacterium bovis• Protective effect against meningitis and disseminated TB in

children• Does not prevent primary infection; or reactivation of latent

pulmonary infection• Adverse effects:

– Pain and scarring at the site of injection– Keloid– Subcutaneously: local skin infection that may spread to the regional

lymph nodes causing suppurative lymphadenitis– Immunocompromised: disseminated infection

Diphtheria Pertussis Tetanus

• Vaccine components: diphtheria and tetanus toxoids, killed whole cells of the organism that causes pertussis (wP)

• DTaP: acellular pertussis- uses fewer antigens than the whole cell vaccines safer, more expensive

• Adverse effects:– Fever– Soreness at injection site– Abscess

Oral Polio Vaccine

• Live-attenuated vaccine• Three doses of live-attenuated OPV produce

protective antibody to all three poliovirus types in more than 95% of recipients

• No side effects

Hepatitis B

• Contains one of the viral envelope proteins, hepatitis B surface antigen HbsAg

• Recommended for babies born to mothers with active hepatitis B infections reducing the risk of mother-to-child transmission

• Generally safe; mild fever may develop 1-2 days after administration

Measles

• Live, attenuated strain of the measles virus grown in chick embryo tissue culture

• Adverse effects:– Fever– Mild rash (7-12 days after vaccination usually)– Allergic reactions- rare

Tetanus Toxoid Immunization Schedule for Women

• When given to women of childbearing age, vaccines that contain tetanus toxoid (TT or Td) not only protect women against tetanus, but also prevent neonatal tetanus in their newborn infants

Vaccine MinimumAge/Interval

PercentProtected Duration of Protection

TT1As early as possibleduring pregnancy

-- --

TT2 At least 4 weeks later 80%

• Infants born to the mother will be protected from neonatal tetanus•Gives 3 years protection for the mother

TT3 At least 6 months later 95%

•Infants born to the mother will be protected from neonatal tetanus•Gives 5 years protection for the mother

TT4 At least 1 year later 99%

•Infants born to the mother will be protected from neonatal tetanus•Gives 10 years protection for the mother

TT5 At least 1 year later 99% •Gives lifetime protection for the mother

•All infants born to that mother will be protected

Tetanus Toxoid Immunization Schedule for Women

Thank you!!!