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Pediatric Immunization (EPI)
Garcia, Garzon, Gaspar, Gatchalian, Gaw, Geraldoy, Geronimo, Geronimo,
Geronimo
Vaccine Min age at 1st dose
Number of doses
Dose Minimum interval between
doses
Route Site
BCG Birth or anytime
after birth 1
0.05 mL -- Intradermal Right deltoid region of the
arm
DPT 6 weeks 3 0.05 mL 4 weeks Intramuscular Upper outer portion of the
thigh
OPV 6 weeks 3 2-3 drops
4 weeks Oral Mouth
Hep B At birth 3 0.05 mL 6 weeks interval from
1st dose to 2nd dose,8 weeks interval
from2nd dose to third
dose.
Intramuscular Upper outer portion of the
thigh
Measles 9 months 1 0.05 mL -- Subcutaneous Upper outer portion of the
arms
Expanded Program on Immunization
Bacillus Calmette-Guerin• Vaccine against tuberculosis• Attenuated live bovine tuberculosis bacillus, Mycobacterium bovis• Protective effect against meningitis and disseminated TB in
children• Does not prevent primary infection; or reactivation of latent
pulmonary infection• Adverse effects:
– Pain and scarring at the site of injection– Keloid– Subcutaneously: local skin infection that may spread to the regional
lymph nodes causing suppurative lymphadenitis– Immunocompromised: disseminated infection
Diphtheria Pertussis Tetanus
• Vaccine components: diphtheria and tetanus toxoids, killed whole cells of the organism that causes pertussis (wP)
• DTaP: acellular pertussis- uses fewer antigens than the whole cell vaccines safer, more expensive
• Adverse effects:– Fever– Soreness at injection site– Abscess
Oral Polio Vaccine
• Live-attenuated vaccine• Three doses of live-attenuated OPV produce
protective antibody to all three poliovirus types in more than 95% of recipients
• No side effects
Hepatitis B
• Contains one of the viral envelope proteins, hepatitis B surface antigen HbsAg
• Recommended for babies born to mothers with active hepatitis B infections reducing the risk of mother-to-child transmission
• Generally safe; mild fever may develop 1-2 days after administration
Measles
• Live, attenuated strain of the measles virus grown in chick embryo tissue culture
• Adverse effects:– Fever– Mild rash (7-12 days after vaccination usually)– Allergic reactions- rare
Tetanus Toxoid Immunization Schedule for Women
• When given to women of childbearing age, vaccines that contain tetanus toxoid (TT or Td) not only protect women against tetanus, but also prevent neonatal tetanus in their newborn infants
Vaccine MinimumAge/Interval
PercentProtected Duration of Protection
TT1As early as possibleduring pregnancy
-- --
TT2 At least 4 weeks later 80%
• Infants born to the mother will be protected from neonatal tetanus•Gives 3 years protection for the mother
TT3 At least 6 months later 95%
•Infants born to the mother will be protected from neonatal tetanus•Gives 5 years protection for the mother
TT4 At least 1 year later 99%
•Infants born to the mother will be protected from neonatal tetanus•Gives 10 years protection for the mother
TT5 At least 1 year later 99% •Gives lifetime protection for the mother
•All infants born to that mother will be protected
Tetanus Toxoid Immunization Schedule for Women
Thank you!!!