Empowering data driven health.

Discovering & Optimizing Your Personal System Biology

E(exposures)N(nutrition)L(lifestyle)

RESPONSEM(metabolic response)

SYSTEMG(genetics)

fG(E,N,L)= M

INPUTS

21st Century = System Biology

Rectangularize Your Aging Curve

age

heal

th

0 60 120

Shifting LanesWhich lane are you in? The earlier you start, the more choice of lanes you have.Age and health are different measurements!

*CrossFit Training Guide, pg19

• Blood pressure• Body Fat• Bone Density• Triglycerides

“Fitness”

“Wellness”

“Sickness”

• Good & Bad Cholesterol• Flexibility• Muscle Mass• Etc.

Based on measurements of

Our assumption is that if everything we can measure about health will conform to this continuum then it seems that sickness, wellness, and fitness are different measurements of a single quality: health.

The Health Continuum*

As time goes by…The quantity of diagnostic data increases exponentially, while the cost to deliver diagnostics decreases

Cost of Diagnostic Testing

Volume of Inform

ation

The Golden Age of Measurement

1990 2000 2010

Total CholesterolA single number

HDL / LDLMeasurements of both good

and bad cholesterol levels

Advanced FractionsDetailed numbers on types of fat, proteins and forms

of cholesterol

of data needed for accurate diagnosis and health management is contained in blood chemistry 70%

Due to huge scientific advances in diagnostics over the past 25 years, we now have unprecedented abilities to predict and manage an individual’s risk of a wide range of lifestyle and other diseases

Deeply Predictive Diagnostics

Blood ChemistryIncredible Information, Currently Inaccessible

Blood chemistry data is extremely valuable for wellness and prevention, not just treating disease.

Over 75% of US adults have low levels of Vitamin D, associated with increased risk of cardiovascular disease, cancer and infectionArch Intern Med. 2009;169(6):626-632

50% of heart attack patients admitted to the hospital have normal HDL and LDL levelsAm Heart J. 2009 Jan;157(1):111-11

More than 1 in 10 Americans have undiagnosed thyroid disease, commonly causing fatigue and weight gainMurdoc Khaleghi, MD

30-45% of female endurance athletes are iron deficient, which can negatively affect performanceMed Sci Sports Exerc 1998, 20:116-121 and 1998, 30:S70

However, it is extremely difficult for consumers to access and act upon this valuable information

Dynamically Changing EnvironmentOver the next 24 months, 10’s of Millions people will participate in the

individual health services marketplace

Carriers must insure by law

and people must be insured

by law Prevention oriented services a key

component of ACA

Mandated federally or at state level

like in MA, depending on political

landscape

Organizations adapting the

way they provide health

services, defined

contributionsPrivate and Government sponsored

exchanges

More and more people

buying health services

directly

Affordable Care Act and Consumer Health Landscape