Circle No. 105 on Readers' Service Card

IIDIIID1IIIII| POSM ONS WA1NTED I1IIIIIDI

Assistant to Research Director/Project Manager,and so forth, position sought by Ph.D. (physics),Augutst 1973. Enjoys helping people in all fieldsof science, enigineering. More than 15 yearsof diversified industrial experience. Box 377,SCIENCE. X

27 JULY 1973

11111111111111111111tl' POSI'HONS WANTED 1|||||||||||||Biochemist-Chemist. Ph.D. 1966. Experience inlipid biochemnistry and in the chemistry of natu-ral products. Well versed in analytical methods-TLC, GLC, IR, UV, NMR, mass spec-trometry and all types of choramtographic pro-cedures. Publications. Teaching experience. Cur-rently on the faculty of a university. Seeksteaching/research position. Box 378, SCIENCE.

x

Biomedical Engineering Ph.D., EE background.experience in electronics and computers, seeksaicadcmic or industrial position. Box 379,SCIENC'E. X

Biophysics, Ph.D., 1969, woman. Four years'postdoctoral R & D and teaching in clinicalmedicine. Three plus years' pre- and postdoctoralteaching experience. Interested in position inwestern Oregon or Washington teaching bio-physics, physics, cell biology, science for non-science majors, immunology, biochemistry, andphysiology. Will consider solely teaching orteaching/research position. Box 368, SCIENCE.

7/27Cancer Immunologist: Ph.D. seeks research!teaching position. Experience and interest inquantitative tumor biology, human tumor im-Lnunology, normal immune profiles, serum pro-tein polymorphisms, analytical and preparativePAGE, histochemistry, immunohistochemistry.immunomethodology, applicable to clinical pa-thology, microbicidal and cytocidal mechanisms.Medical (pathology), paramedical-graduate teach-ing (microbiology) experience. Publications. Willconsider challenging research position. Box 380,SCIENCE. X

CNS-Behavior Neuroscientist, Ph.D. 1972, de-grees in psychology, pharmacology; clinicallyrelated postdo.. in psychopharmacology. Seekspermanent position or 1-year postdoc. leadingto research/academic position. Twelve papers inpsychobiology of memory, motivation. Box 381,SCIENCE. X

Ph.D. Cytogeneticist; experience in human andmammalian chromosomes, tissue-culture, amnio-centesis and teaching in genetics. Box 382,SCIENCE. X

Developmental Biologist, Ph.D. Author of atextbook and many articles. Teaching-researchexperience, 8 years. Seeks teaching, teaching-research position. Box 383, SCIENCE. X

IIIIIIIIIIIIIIIIIIIIIllillj llPOIT ONS WANTED'1111111111111uEinvironmental Impact Analyst. U.S. and overseasexperience in environmental and economic im-pact analysis, engineering, and management. U.S.citizen, B.S. enigineering, Ph.D. physical science.Seeks position involving environmental impactanalysis for major engineering projects. Willingto travel. Box 384, SCIENCE. X

Immunologist. Ph.D. Experienced; research; man-agenrent; publications. Specialist in medical im-muinology, particullarly in area of diagnosticlaboratory techniques. Interested in a senioiposition withini a challenging environment. Box385, SCIENCE. X

Pharmacologist: Ph.D. Five years of postdoctoralexperience in autononlic and endocrinology. NIHtraineeship in diabetes. Sixteen publications.Seeking research, teaching, or government posi-tion. Patel, 4660 Waldo Avenue, Riverdale, NewYork 10471. X

Professorship-Chairmanship-Research Position, 1973or 1974. Ph.D., numerous publications, goodreferences, experience in electron and lightmicroscopy, neurophysiology, cancer research,teaching. Box 386. SCIENCE. X

Science and Engineering Information Specialist.18 years' experience information gathering, com-mtunication, and analvsis (meeting, laboratoryand supplier visits; literature searches; etc.)in industry, university. Education: physics. nu-clear engineering, applied mathematics. SeeksinduLstrial, academic, government, or foundationposition. Box 387, SCIENCE. X

PO|||||||||||||SITIONS OPEN|||||||||| |TERRESTRIAL ECOLOGIST

Terrestrial Ecologist is needed to develop andsupervise contract programs that describe theexisting environment and assess the impact ofdisruption to the natural systems. He will beresponsible for planning, proposing and managingfield programs and analysis. Applicants shouldhave a doctorate, systems orientation, some yearsof responsible experience and entrepreneturialskills. Send curriculum vitae and salary require-ments to Mr. B. Mulnard, Grumman EcosystemsCorporation, Bethpage, New York 11714.

381

Schwarz/Mann m

Bulletin Board

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Please write to Schwarz/Mann

Division of Becton, Dickinson and Company [B

Orangeburg. New York 10962

Telephone 914-359-2700

SUPERVISOR

BIO-CHEMICAL PHARMACOLOGY. . . to have responsibility for bio-chemicalaspects of food additive and drug programsincluding design of protocols for determiningmetabolic rate, pharmacokinetic studies, bio-availability determinations. Will supervise staffincluding several Ph.D.'s.

Requires a Ph.D. in Pharmacology having strongbio-chemical interests and one who is an ex-perienced investigator with supervisory expe-rience. Candidates should have at least 4 years'experience in industry.

Excellent opportunity to work as part of a top-notch medical research department in a dy-namic growth organization. ICI AMERICA (in-cluding the former Atlas Chemical Industries)is a subsidiary of one of the world's leadingindustrial organizations. Send resume in con-

fidence, including present salary, to:

DONALD P. WHITELEYDepartment 2001

ICI AMERICA INC.

Wilmington, Delaware 19899

An Equal Opportunity Employer

PersonnelPlacement

It is requested that only those employerswho will not discriminate on the basis ofrace, sex, religion, color, or national originsubmit positions open advertising.POSITIONS WANTED: 400 per word, mini-mum charge $10. Use of Box Numbercounts as 10 additional words. Paymentin advance is required. These rates applyto individuals only. Personnel agencies andcompanies take display rate for all adver-tising.

POSITIONS OPEN: $110 per inch. No chargefor Box Number. Rates net. No agencycommission allowed for ads under 4 inches.No cash discount. Ads over 1 inch will bebilled to the nearest half inch. Payment inadvance is required except where satis-factory credit has been established.

COPY for ads must reach SCIENCE 4 weeksbefore issue date (Friday of every week).Send copy for Personnel Placement adver-tising to:

SCIENCE, Room 2111515 Massachusetts Ave., NW

Washington, D.C. 20005Replies to blind ads should be addressed

as follows:Box (give number)SCIENCE1515 Massachusetts Ave., NWWashington, D.C. 20005

00,11

AQUACULTURE RESEARCHDEPARTMENT HEAD

A l) ili t i I ,, irnc rF tuclL C ftC

sncnior positioni ini ttieic 5ynte x AcinueCnilU ire

scielnces Divisu onri t'I,lo i ut irni rutiInn J LI t tiIc nII nIt ( iaI L ItiCCF lIC

iitl iI unntII cS f intesetlseI\ tIIL lSiI c

-C t not i IIinIn L tl ii t ri

pr;F nil rc is ot situnnsL i etnitYIIII Ir ItI1- iF I L I IIr Is-i C 1ICmseIti 11r n-

t irntri,o It c lnp II IIt, I I () C l tunI

ont letirini' iud ir iorn cdI citiueu ils forLires 55, ittc r qinitu is 1111011" rtun rs.

anIlLt I It nicS t1r LIuImLI pi Si sse .inI Nl. S. Or

1n1h i). rsithsr l rs ot x1 Fri uic.Iun iL iIcL ti in-ue I nI i c nitr I reSe; i lI

mtiit?1. I'rcf r viicc ii tnh ic Iivci i t Fr-soCii itli eSxt ricCilee ir illntiun] -cni uClt rig,L . I l(on nm/ruin hiI. RI fleui Ser

Struld hse itddrcseel ti: Karl MIcCalla,Perseiuuael Department, S ntlex Corpora-tion, 34011 Hills iew Xsenue,nu. Palo AIto,California 94304, 415-855-540)1 (icoIlet

SYNTEX

SC RIPP'1S INSI I I U-FIN OF ()CE[N0t-AIPUI'sY invliets arpplicatioun for position it the

.ssistlant or Associale Proafessor Iervl rwith .kiitr-CIC i h .lind tC C llg rlte rcst IIi hrond raolgcuf runItt1(li ftiltl rlnt th ticoci ii.il aipproacetis

to C _n()li() I nC-i)i't ill tire .ia ri cn c flriFi -l

erCIIt. iiiet i,ihl,rI n HII Spr i mIompeterce iII

IIIsiititii(i ,I Ir I Iu na d. iri-I() 'o i laI oceii1Og-rF.ph5. Fcrt to hc eict Frmitiied bhr cilli ficatirris.ridiC CLri-1irLLtinirl ritic t hi li ri' rniphts .irict list of

ieir s to: P'rofessor Jaimies I'. Fnriglut,Scrip)ps Institution of Oceanographi, Box 1529.l a Jolla, California 92037. Te l Univer.itiiofaliri/ iai a Itqul ii|)ippo itrn 'il (i m ulb)nu,v r iw it/i

Ithif/ ri l ( c irirr i proi -au

F ACI I.II% POSITION IN BIOCHE.MISTIRY.Re e Fet;irc l-tC rtlic ire ponsitrnir ll idble imrmeliatelsAIi s,,'i ii PrOtre s in et' OF psossibly hiiher.i3inchemlli it in ial viraLSls CFus IIsZVnCs,Illerrhi,iesr ii- rireiirholousvs (Candiretate muLst bere-tiS' ic15 .i'trei itli poistdlictorit expereri cc.W5 rirnieri a d mmiiOrirFity c rdlCelteS C'ieCOLirigecl, cs-

peeialls thiose initcrestecl inl helping rFcrLiit gi-aclu-itC st Lid iis. Dr. N1. V Simpson, Departimientof Bioclheniuistri, State U nisersity ot Ne V orlk.Stony llrook, N.V 117901 All e qu/iil (q)pmor irirritl

B110CHFINIIIIS, hl).

Ex eeltent protr 'sSionlil Stalfl n-)i FtiL iIi ty atmo ce i-ii. ()(iii )-h ( 1,i rsmisFi tiluitcdl ho pluitlcerietFr Fo l io cih ist, PIr .), riits experielice illeFiiFm nF ret in tl,lCtim(u liituIuOll .iirClli Lltitlia rrtiol

of eliromirioiri riliFpt i nirl electrotplioretic tece -

liqtics. I S eiti/Cisilp rFeqLirred. Send ciriipleiteCiFrriCiiliMni ritie to: Dr. leo N1. Mleyer. Chiet,Heniatologs Section. Brooklyn V.A. Hospital.800 Po!r lllace. Brooklyn, Ness York 11209.

A psir iili i ,ns direc tor of liec L,isorriioir et'letal Medicine ill nurirsirsits-atitliated hospsitilIis .avarlable for a Ph D. BIOCH NIMIS' ' possess-imi hurr postdoi tor trlir nlt 'ild excselleiit rFe'-I'C11 CC,. I rs lLIitiCS i't ii5l clUde siipcrFisiorii l)t

ti eC liriiiec tliii,2it ser 5C it istat F,ii F5torvtrld cr;cmii 'i;f un iiidepeirele r-esialrcF programFlof tisciIooris ls ill tiire - ncral . rFCi of fet;.1nlictabolsntnill or desvetirispmcrit. C onopr'atiSc rFseiFlrchpriliects witrI S Fvr l LIiii irsitv delnimrnenits areciurrenitlI Liiil ti its. A ppFropri.ite fict ilts r,miiik

ill IIL'tecieFed Ii he is lie t Iris isiii

I-letern

ci pre ii irsse'tic iiie plic' riit ie

T

,l*iil lpt itili ,l lol s itsl ptie, itiiterestus dicho tl ,,l.si IC''IrCII o.lr i'ts aplpliz;atioll to) clitil-eelied t t

SCei ictniCUILirli vitae I)r. J NI. Gibbons,Director of OB-GN'N. St. F ranicis Hospital, 114Woodland Street. Hartford, Conii. 06105

CFIL BIOLOGISTSVIROLOGlISTIS

lIir setelipii nuipeiii s ,iv, nilalelr flo- iCecelt Phs.D 'ssith iirnii ill cell liollegys soiimatie ccll g-lie tics, tiriisiFr irolonsv imr minosnlosgy, lipici hio-tltlit- SciiLl compleltt rC'SL1rn6 to:

Nliss Sandy D)'AXmbrosio'Wistar Instituite

36thl and Spruce StreetsPhiladelphia, PennsOIania 19104

1 ,s'

DIE AN, SCHOOI OF MEDICINE

tIl *n i rt ot \Arkias,is ainounctclteir2s a vacancsiII thc so'moilotr I)Ci 1 of ti S tril sto of N lvi-

in i tI irk reste-, quii lified person ls to(i!iir wi re>. tic hl of .A Mledical C'enter is

,m1 id ispporUl lflitO eniplrovcr. Iniqu iries S 0tni ld

w liii ii trhe ice President for HealthidSlencs. ltiniersit oft Arkansas Mledical Center,Markhamr at Hooper Dri c. l.ittle Rock,Arkansas 72201.

()I'P TtTIANilII N1L DIC1)1CA DIt CA lION-COMUIPTIFR-ASISTED INSIRUCTION. Ph.).Oi- N1 1) tmi liect id3/ ir pirticlipate ini transter( zit j ' IIIii irk d k.itc d Cdt icati -Ir to lJni-rL is.ttfItirir l NA-) s%stcrn. NILst be crct-tirc 11 SC FIroll miterFe t iti ccldi atirsiril process.ildi Ii(),l hirk roF i hiologic,il sciences.

Ii .ini siloitiri CIitiC()r C eriricUr ilurti VitaC andkisti crrf rs to Dean, M1edical School.1205 W est Calitornia. t'rhana, Illinois 6180I1.

INSTIIIAt OF1(I ASlIOLOGYNlcGII I I NITI RSITY

Ap5plic itio ss are' irs rted froisi esitilstished scr-c'ilt tI t'l(i tIe' positiorn ofi'-ofessosr aird lDirector1 i ll, s itini c.in eli is swsell eqdi-pisedl tior rF-.C' ircl it C pcFi- iscrIt lp.irFisitolo-5 Tlle post;1 is uron c nivt.llste in thIr sirir nserotF 1974.

Il .Clriqu ilie ) ,q5p lr,i riM IS lii()nlld hIs teo :

Proftesor tF. J. StanshuriD)ean, F acults of ScieniceMcGill U'nisersif3lIoirtreil. P.Q?., Canada

PFI 1MMACXOLOGISTS, PHY SIOL OGISTS.GENE' 'ICISTS and HEMAT4OL,OGISTS

Tlr I'eoria Seliosol of Nlcdicinc, .a 3- sar elitricalsclwwl ini tir Uniesersity of Illlrrlr s, Coilclg ofMleceliCiur, tsas l'ocir stilf positirols for pst erns

ier ciii tca cht riCeir ri'SelereCCer. erndoc r iinolto gys -Ce-IMiC'Sties, uissrss1, rlogs or helrcn itolo-v in ai itrite-

,iir l iriFCin s,S P o iF,ili ir l ithe clin eitac iFr,. Atpplicanits miiust riold the Ph.). or Mi I).

ith ar rirrii tiiiriir of 2 years' experrerrce and willtse extccted to desvelop resealrch prograrills innCeiMUrrniiesity-reltred aireas. Peoria School of NIedi-

ilew is .1 11esW school offerin, ciallengirru op-portuiliiti irs edeic atirn anrel research. johLecserilptiini is oiirterqse (ri Iequest. Applic trit 5srirli CrriFFiei1ihum sitrle arid lettitrts of reconirrsseir-ciiti nl sltiolel hi semit to the Coordinator ofIlasic Scienice P'rogranm, Peoria Scheool of Mledi-cine. 1400 W'est lIain Street, Peoria. Illinois

61606 Tl/u inuJnih /lhnI i nI i .ini ntII I lit

POSTIDOCT1ORAXL. FFELIOW in snopsivs csi, pihti-(1us0(te CCliuIlinr plIn sirotogv or tsioclhernistivis ie-

et il'iI l iiirsniL inI si i-)el sick1renoicCtClo,iidOrf".llzt. I t rl zltl If Cllltbi j-)inail;rN i-ese"lti c rn r miii l ti cli s i re i5

ui'()LIP sIr C,C ti Ii t, i rllMiLSi irr riS nlI FrptI I OI i stsIrs ni sis sliS siolonii ni) cre io pirl nrethronis tost r"I- ate nuISlItLi ruIIt Cell ts pcs of msianrsr,mlid an

"i . t'esitiii ; ailstlse Inm ne iately.sSCendI rFs nlmin: Dr. ILee Hoffinani, Department of Miedicine,Albert FEiunstein Cellege of MNTedicine. llronx, N.Y.10461,

The Market Place

. s:"E L' A:IJ :i ee'L_

=~ ~ ~~~~a;S~6

SCIENCE, VOL. 181

PH.D. SUNIIORMICROBIOlOGIST

with experience inANTIBIOTIC PRODUCING ORGANISMSfor high-priority program involving studiesof fermentation and production of new anaLiseful antibiotic substances. Background inbiosynthetic processes and strain selectiondesi rable,

Schering, a major pharmaceutical com-pany with a history of notable success inantibiotics, carries orn a vigorous researchprogram and offers excellent facilities andsupport services. Our suburban location isclose to New York City, Please direct resumeiro confidence to Research Personnel

SCHERIN1G60 Orange St.Bloomfield, New Jersey 07003

Applicants of all races are encouraged to applyFemale-Male

BIOCHEMISTNew England Nuclear Corpora-tion, located in Boston, Mass.,is currently seeking a chemist tomeet the demands of its rapidgrowth and expansion.

The position of biochemist is newand will offer the most qualifiedapplicant an opportunity to de-velop within an established group.

This position, which reports di-rectly to the Group Leader, willbe involved with preparations ofradioactive (Carbon-14, Tritiumand Sulphur-35) amino acids. Inorder to optimize within this con-text, you should have substantiveexperience in the chemistry andbiochemistry of amino acids. Youwill also be expected to have a

working knowledge of biosynthe-sis and the metabolic interconver-sion of amino acids as well as theirisolation and purification at amicromolar level.

Successfu! candidates will be of-fered an excellent compensationpackage which includes interviewand relocation expense reimburse-ment. We are suggesting that qual-if ied individuals submit resumeand salary history in completeconfidence to J.R. Chabot, C/OPersonnel Division, New EnglandNuclear Corporation, 575 AlbanyStreet, Boston, Mass. 02118 orcall collect for information,(617) 426-731 1, Ext. 338.

New England NuclearAn Equal Opportunity Employer

Attention

ULTRACENTRIFUGEusers Density Gradient Markers

1 mm calibrated spheresPat. No. 3,437,266

available through a Instruments1117 California Ave., Palo Alto, CA 94304-for special densities send inquiriesd'irect toREPRODUCTIVE SYSTEMS, INC.P.O. Box 304, Dept. B, Menlo Park, CA 94025

I

I 11 .,POSITIONS OPEN 1'-OSITIONS OPEN POSI'l-IONS OPENI o., 1 11111111111

Only the new Sorvall OTD-2 Ultra Centrifuge hasOil Turbine Drive.

Gears, belts, and motor brushes are a big dragwhen it comes to fast, efficient ultra-centrifugation.Which is why Sorvall engineers developed the exclusive,patented Oil Turbine Drive for our new OTD-2 UltraCentrifuge.

Oil Turbine Drive uses very few moving parts-fewer parts, less trouble-and the turbine itself touchesonly the drive fluid. Uneven bearing loads are practicallyeliminated; vibration, friction and wear are cut to thebarest minimum. Result: less drag. And when you haveless drag, you get better ultra-performance. Whichmeans speeds to 65,000 RPM and RCF's to 424,000 g-smoothly, quietly, reliably. The Oil Turbine makes thebig difference in drive efficiency; but what about the"brains" behind all that drive?

The logical capabilities of this centrifuge are, ina word, multi-dimensional. Just a few simple controlsdirect all major operating modes-press a button and

the electronic logic does the rest: The OTD-2 is com-pletely self-programming. Conditions are set up auto-matically to suit the requirements of your particularprocedure and your valuable sample. You can evenpre-cool the rotor. Back-up and double back-up systemsprotect all the critical functions, and a self-diagnosingsystem of checks-and-balances keeps things like speedand temperature right on. Protection circuits prevent no-load and overspeed operation. A key lock rules outunauthorized runs.

The OTD-2 also features an interchangeabledrive cartridge, easy-to-clean rotor chamber, and stain-less-steel top. Used in conjunction with angle, horizontaland zonal rotors-including Sorvall's specially designedUltra Rotors-the OTD-2 provides truly superior per-formance in the ultra range. Full details are yours forthe asking: just write or call Ivan Sorvall, Inc., Newtown,Connecticut 06470. (203) 426-5811.Ask for Bulletin SCE-7UD SR

Circle No. 112 on Readers' Service Card

HA 67CO59IR1I35O YI N iZ13MRS ROBINOWBaGM,ED LIB/BILMOUR HLIt'CMASTER UNIV'4AMILTON O0 OK:' CANixtui ulpto FiveDNA Denaturations,

Simultaneously!. . . with Varian Techtron's newAuto-5 Cell Programmer!Thermal denaturations of DNAestablish its uncoiling temperature,indicating the number of G-C pairspresent. This DNA "melting point"(T,) is also influenced by pH, ionicstrength and solvent polarity... andand the simplest way to study these

CalfthymusDNAdenatur-ation

1.1

1.0

I

0

~cc>1C 0.9

a

0.

A .- B

Temperature,C 40 50 60 70 oM ut. , ,x

Thermal Denaturation of DNA: Effect of ionic strength on Tie. Sample: calf thymus

DNA dissolved in pH7 phosphate buffer A==0.005M with KCI additives: Curve A: no

KCl; Curve B: 0.005M KCI; Curve C: 0.05M KCI; Curve D: O.lM KCI; Curve E: control.Range: 0.5 abs full scale with 0.8 abs initial zero suppression. Wavelength: 260 nm.

effects is tosolutions sinsamples heaAbsorbanceare easily cc

The VaritrophotomelProgrammeReadout Acmulti-samp]... as showrcurves at tb

Push butdual turretsreference ir*For meter versio

Circle No. 3 on

for any interval up to 60 sec-

onds, with up to 60 minutesbetween each set of readings.

seompartment. _Each sample may have its own ref-

e compartment. - erence or all may use the same,

analyze several DNAwith the reference turret locked in

nultaneously. With all one position. Both turrets index

Lted uniformly, theprecisely in the optical path ... and

-tempedruniorey cves are simplv lifted out for convenient

-Temperature curves cell transfer.

)mpared. Optional modules for

an Techtron 635 Spec- the Auto-5 Programmer

ter and the Auto-5 Cell include multi-zero and

r, with Temperature multi-range* capabili- _,cessory, perform these tle Tm,, analyses handily ties: the instrument zero

and the miost suitable

n by the denatulration absorbance span can be

ie right.

ttons program the Auto-5 preset for each of the five

each pair (sample and sample/reference pairs.,:terialh may bmestudied You'll find the Varianiaterial) may be studied Techtron 635 and Auto-5

Ononly (Model 635) Programmer indispens-

Readers' Service Card

varian instruments (V|

Brand names: ANASPECTT* CARY® * MAT * VARIAN®

VARIAN AEROGRAPH® * VARIAN TECHTRON

able whenever multiple samplescan be run simultaneously: in kineticassays, analysis of column effluents,titrations . . . even the most complexreaction rate studies become routine.

At Varian Instruments we designsimpler ways to answer your lifescience problems ... may we sendyou free literature showing how?Write 611 Hansen Way, Box D-070,Palo Alto, California 94303.

C * D

iCIA