Philippine Council for Health Research and Development

Philippine Council for Health Research and Development

List of GIA Projects

FY 2021 GAA

Project

Duration Implementing Agency Beneficiaries

Original

Program: Drug Discovery and Development 120,998,595.16

Phase 2/3: Myko-mining of Wild Edible

Mushrooms and Other Allied Species

in Central Luzon for their Medicinal

Properties

The project aims to screen Philippine edible

mushrooms for anti-inflammatory, anti-

hypertensive, anti-hyperglycemic, anti-microbial

and anti-cancer activities and document traditional

knowledge of Filipinos on mushrooms and its

cultivation;

2017 -2024Central Luzon State

University

Mushroom farmers; Nutraceutical, food

and pharmaceutical industry; Local

population considering the rise of lifestyle-

related diseases

6,000,000.00

Compounds Active Against Cancer Cell

Lines (HCT116, MCF7, A549) from

Priority Extracts

The project aims to generate drug candidates

active against cancer cell lines from the DDHP

Bioactive Extracts sub-program.2019 - 2024

UP Diliman-Institute of

Chemistry

Biotechnology, pharmaceutical

companies, and other private investors

who will commercialize the products after

the technology transfer

Patients suffering from chronic

inflammation and pain

3,000,000.00

Integrative Laboratory Animal

Testing of Medical Devices for

Abdominal and Musculo-skeletal

Disorders Program

Proj 2: Restraint and anesthesia for

laboratory animal testing of medical

devices: Conventional methods and

pain assessment

2018-2022 3,000,000.00

Proj 3: Open Surgical,

Endoscopic/Laparascopic Approaches

for Application of Gastro-intestinal

Medical Devices and Peri-Surgical

Imaging for the Surgical Control of

T2DM

2018-2023 15,000,000.00

Proj 4: Wound healing and post-

operative management using

conventional and alternative

approaches

2019-2021 2,881,645.00

Proj 5: Development of good quality

laboratory animals for research2019-2021 307,020.00

Synthesis and Derivatization of

Disease-Specific Bioactive Hits and

Lead Compounds (Phase II)

1. Synthesize bioactive compounds with activity

against inflammation, diabetes, hypertension, and

cancer.

2. Conduct toxicological screening and

confirmatory assays on synthesized bioactive

compounds.

3. Conduct in vivo animal testing.

2017-2024UP Diliman - Institute of

Chemistry, UST, MSU-IIT

Researchers; Academe; Filipino

population; Local herbal and

pharmaceutical industry

6,000,000.00

The Animal Surgical Laboratory Program aims to

develop more effective, efficient, environmental-

friendly, sustainable and humane methods of

utilization of the medical devices in animals for

subsequent application on humans.

Program/ Project Title Objectives / Deliverables/Purpose 2021 GAA (Total)

1 of 22

Project


Original


In vitro toxicity testing of Bioactive

Plant Extracts with Activity against

Diabetes Mellitus

1. Conduct In vitro toxicity testing on plant extracts

with bioactivity against Diabetes Mellitus.

2. Isolate bioactive compounds with anti-DM

activities.

3. Conduct animal studies.

2018-2020 Visayas State University




2,000,000.00

Discovery of Cardiometabolic

Bioactives from Plants in Central

Philippines (USC TLDC Phase 2)

The USC-TLDC program intends to discover

cardiometabolic bioactivies that can be used as

complementary medicine for the treatment,

control, or prevention of hyperglycemia,

hypertension, hyperlipidemia, and

hypercholesterolemia.

2018-2023 University of San Carlos




2,000,000.00

Cellular and Molecular Effects of the

Combined Formulations of the

Sampung Halamang Gamot

The aim of this project is to determine the cellular

and molecular basis of the anti-cancer

antimicrobial and prebiotic potential of the

combined extracts of halamang gamot and to

establish their metabolite profiles.

2018-2024 UP Manila




2,000,000.00

Disease Specific Bioactive Hits from

Terrestrial Organisms (Phase 2)

The program will work on the isolation of the

bioactive hits for various disease indications from

the plant extracts that will be found to be the most

active in the on going program "Extracts from

Terrestrial Organisms for Bioactivity and Toxicity

Assays (Phase 2)"

2017-2024

UP Diliman, UP Manila, UP

Visayas, University of

Eastern Philippines, Palawan

State University

researchers, academe, pharmaceutical

industry and nutraceutical industry 3,000,000.00

Discovery and Development of

Natural Products from Mindanao

Marine Resourcses

Project 1. Anti-Cancer Drug Leads from

Marine Sponges Collected Off the

Coasts of Mindanao

2018-2024 1,000,000.00

Project 2. Seahorses and Pipefishes

with Pharmaceutical Potentials from

Selected Areas in Mindanao,

Philippines

2018-2024 2,000,000.00

Formulation of Disease-Specific

Standardized Herbals for Pre-Clinical

and Clinical Development (Phase 2)

The program will work on the standardization and

formulation of the next set of priority plants that

will be identified under program "Discovery and

Development of Health Products" for

inflammation, hypertension, diabetes and gout

2018-2024UP System, Pascual Lab,

Herbanext, Pharmalytics Inc.


industry 5,000,000.00

Pre-Clinical Development of Priority

Plants as Herbal Drugs

The program will work on the isolation of the

preclinical testing of plants that will successfully

pass standardization and formulation tests under

on going program "Formulation of Disease-

Specific Standardized Herbals for Pre-Clinical and

Clinical Development

2018-2024UP System, Pascual Lab,

Herbanext, Pharmalytics Inc.


industry 5,000,000.00

The general objective of this study is to provide

baseline data on important sponges and

determine associated bacterial community

composition with medicinal potentials in selected

areas in Mindanao. The study will assess and

characterize important species and associated

microorganisms as well as existing habitats in

different areas in Mindanao. Various crude polar

and non-polar extracts and pure compounds from

marine sponges collected from different regions in

Mindanao and subject them to bioactivity assays.

MSU-IIT

researchers, academe, Filipino

population, local herbal and


2 of 22

Project


Original


Anti-hypertensive and Cholesterol-

lowering Bioactive Hits from Priority

Bioactive Extracts

The program objective is to isolate and elucidate

the structures of biaoctive compounds from

priority bioactive extracts against specific

diseases; to determine nephro-, hepato-, and

cardiotoxicities of bioactive fractions; and to

confirm the bioactivities using orthogonal and/or

secondary assays.

2018-2024UP DIliman Institute of

Chemistry




1,000,000.00

Structure Identification of Anti-

Inflammatory and Anti-Pain Agents

from Priority Bioactive Extracts







secondary assays.


Chemistry




1,000,000.00

Anti-diabetic Bioactive Hits from Priority

Bioactive Extracts







secondary assays.


Chemistry




1,000,000.00

Phase 1. Safety and Dose Escalation

Trial of Orally Administered Fixed Dose

Combination Capsule of E. hirta + L.

speciosa + Z. officinale in Healthy

Filipino Males under Fasting Conditions

1. To determine maximum tolerated dose (MTD)

of Fixed Dose Combination Capsule of E. hirta +

L. speciosa + Z. officinale administered orally as a

single dose under fasting conditions in healthy

Filipino study participants

2. To determine the safety and tolerability profile

of different doses of Fixed Dose Combination

Capsule of E. hirta + L. speciosa + Z. officinale

administered orally as a single dose under fasting

conditions in healthy Filipino study participants

Specifically, the study will look at the effects on

the following parameters: electrocardiogram,

hematology, blood chemistry and vital signs.

Toxicity assessments per organ system will also

be performed.

2019-2022 Pharmalytics CorporationResearchers; Filipino population;

Pharmaceutical industry 5,000,000.00

Potential Anti-Cancer Leads from

Plants in Region XII (USM-TLDC) Proj

1: Screening of plants from Region XII

with Potential Anti-Cancer Activity

The program aims to estblaish a Tuklas Lunas

Developemnt Center in Region XII and to develop

anticancer compound/s derived from non-toxic

bioactive plant extracts in the region.

2020-2022Univerity of Southern

Mindanao

Researchers; Filipino population;


CARAGA TLDC

The program aims to estblaish a Tuklas Lunas

Developemnt Center in CARAGA and study the

potential medicinal applications of the biodiversity

in the region.

2019-2025 CARAGA State University Researchers; Filipino population;


3 of 22

Project


Original


Tuklas Lunas from

Endemic/Indigenous Plants in Bicol

with Pharmacological Activity against

Diabetes, Obesity and Hypertension

Project 1: Screening for anti-diabetic,

anti-obesity, and anti-hypertensive

activities and toxicity evaluation of the

plant extracts

Project 2: Bioactivity validation and

orthogonal assays

Project 3: Chemical profiling and

standardization of the bioactive plant

extracts\

2019-2023 Bicol UniversityLocal community; Healthcare sector;

General public 3,000,000.00

Project 2: Bioactivity validation and

orthogonal assays2020-2023 Bicol University

Local community; Healthcare sector;


Project 3: Chemical profiling and

standardization of the bioactive plant

extracts

2021-2024 Bicol UniversityLocal community; Healthcare sector;


Microwave-Assisted Synthesis,

Characterization and Molecular

Docking Studies of Quinoline-4-

Carboxylic Acids and Hydrazide

Isosteres with Antitubercular Activity

The main goal of this project is to synthetically

prepare, characterize and assess the inhibitory

activity against Mycobacterium tuberculosis

H37Rv and in silico binding to mycobacterial enoyl

acyl-carrier protein reductase of quinoline-4-

carboxylic acid and hydrazide derivatives.

2020-2022 University of Santo TomasResearchers, pharmaceutical industry,

healthcare sector 1,987,181.36

Chemical and Biological

Characterization of Pure Bioactive

Compounds from Kadios (Cajanus

cajan) Seeds and Formulation of

Anribacterial Ointment

To develop an effective and accessible

antibacterial ointment from Kadios against

multidrug resistant S. aureus and characterize the

active component to provide a validated claim on

the health benefit information of Kadios beyond its

basic nutritional value

2020-2022 University of San AgustinResearchers, pharmaceutical industry,


Establishment of Tuklas Lunas

Developement Center in MIMAROPA

The program aims to establish a Tuklas Lunas

Developement Center in MIMAROPA region; that

will develop (1) potential herbal products based on

the available resources with the region, (2)

Capacitate human resources and (3) Physical

Infrastructure for in the area of drug discovery

2020-2023 PSU, MSC and WPUResearchers, pharmaceutical industry,


Establishment of the Tuklas Lunas

Development center in CALABARZON


Developement Center in CALABARZON region;

that will develop (1) potential herbal products

based on the available resources with the region,

(2) Capacitate human resources and (3) Physical


2020-2023 UPLBResearchers, pharmaceutical industry,


Project 1: Conduct in-vitro screening of the anti-

diabetic, anti-obesity, and anti-hypertensive

activities of the plant extracts from the Bicol region

and evaluate the toxicity of those found to be

bioactive plants

Project 2: Validate the activity of the bioactive

extracts using orthogonal assays

Project 3: Develop a chemical profiling method to

characterize and assess the quality of the

different plant species

As a whole, the program aims to discover and to

develop potential herbal or drug candidates

through exploration of bioactive plant extracts

from the Bicol region. The overall research and

development process will advance Bicol

University's capability in drug discovery and

development relevant to the establishment of a

Tuklas Lunas Development Centre (TLDC) in

4 of 22

Project


Original


Establishment of Tuklas Lunas

Development Center in Zamboanga

Peninsula


Developement Center in Zamboangaregion; that

will develop (1) potential herbal products based on

the available resources with the region, (2)

Capacitate human resources and (3) Physical


2020-2023 WMSU, UZ AND ADZUResearchers, pharmaceutical industry,


Program: Diagnostics 41,984,598.90

Development of Nanomaterial-Based

Point of Care Test for the Detection of

Pathogenic Bacteria

Availability of point of care test for testing and

screening for common urinary tract infection.2016 -2022 St Luke's Med Cenater

General population; Researchers; Health

professionals; Health Industry; Policy

makers

1,200,000.00

Isolation and Characterization of Lectin

from Different Species of Mushroom

and the Development of Lectin-Based

Biosensors for Food-Borne Pathogens

Purified lectins would be used for the

development of a biosensor for the detection of

common food-borne pathogens

2019-2023 CLSUResearchers, Pharmaceutical, Food and

Medical industry2,000,000.00

The Biochemical and Immunologic

Characterization and Cross-Reactivity

Studies of Allergenic Local Pollen

Extracts

Becaues the flora in the Philippines differs from

that of Western countries, local pollen extracts

have to be prepared and characterized to be able

to describe the allergenic proteins or molecules

present since these allergenic proteins may

produce clinical reactions in the Philippine setting.

Project will produce recombinant proteins that can

be used for the panel allergens.

2018-2021

Department of Pediatrics,

Philippine General Hospital,

University of the Philippines

Manila

Patients with allergic rhinitis and/or allergic

bronchial asthma, and Allergists6,000,000.00

Responding to the Philippine HIV

epidemic: An HIV Drug Resistance

Surveillance Library and Development

of Molecular Diagnostics for Drug-

Resistance Detection Part 3:

Development of Rapid Diagnostic for

Detecting Lamivudine Resistance

The project aims to develop an affordable and

accurate near-point-of-care diagnostic kit for rapid

detection of HIV resistance to lamivudien (M184V)

and will explore applicability of thist platform to

other resistance mutations.

2018-2023

National Institute of

Molecular Biology and

Biotechnology, Natutal

Institutes of Health,

University of the Philippines

Manila

HIV patients, researchers, and academe 8,000,000.00

Development and Evaluation of a Cell-

Based Assay for Malaria Elimination

Although conventional methods of determining

parasite infection in humans and anopheline

mosquitoes remain as the source of direct

evidence of parasite absence or presence in an

area or population, the use of serological markers

as complimentary methods in proving the

attainment of malaria elimination has now become

valuable and worth pursuing. This need has

driven this project to develop a cell-based malaria

assay to detect antibodies to P. falciparum and P.

vivax merozoite surface protein and apical

membrane antigen.

2018-2021College of Public Health, UP

Manila

Malaria endemic communities, malaria

control program, policy makers and

research community

3,000,000.00

5 of 22

Project


Original


Hepato-Renal Conditions in Wistar

Rats under Prolonged Chronic Binge

Ethanol Feeding: Predictions Using

Multi-Layer Perceptron Neural Network

This study aims to create a prediction model that

will determine the degree of injury in the liver and

kidneys of mice under chronic-binge ethanol

feeding. The predictions on the severity index of

hepato-renal injury will be assessed using a Multi-

layer Perceptron Neural Network.

2019-2023Mariano Marcos State

University



makers

1,000,000.00

CRISPR-based Diagnostics (CRISPR-

Dx) for the Detection of SARS-CoV-2

and TB

development of rapid diagnostics for infectious

diseases endemic to the Philippines; exploid Cas-

based reagents and molecular tools to effectively

and cost-effective pre-amplification method detect

and discriminate SARS-CoV-2 and M.

tuberculosis infections

2021-2024 NIMBB-UPD

healthcare system; healthcare

practitioners (minimal training to operate);

and ultimately for wellbeing of Filipinos

8,870,705.90

Enteric Solutions: Development of a

Vertical Flow Microarray (VFM) for the

Detection of Enteric Viruses

development of a vertical flow microarray and

RPA-based assays for the detection of

noroviruses, astroviruses, rotaviruses, hepatitis A,

hepatitis E and Enteroviruses (polioviruses)

2021-2024 NSRI-UPDpatients suffering from gastroenteritis,

medical practitioners10,913,893.00

Establishment of a New Predicting

Indicator of Severe Dengue Fever Prior

to Secondary Dengue Infection

This research program aims to establish a

predicting indicator prior to secondary infection of

dengue fever for reducing severe dengue burden,

and to develop a high-throughput method to

measure the indicator.

2019-2022 St. Luke's Medical Center



makers, Dengue vaccine researchers

1,000,000.00

Program: Omic technologies for health 43,955,023.93

"IMP-XDP": Investigations on the

Molecular Pathogenesis of X-linked

Dystonia Parkinsonism

Project aims to identify and elucidate molecular

mechanisms contributing to XDP pathogenesis2017 -2021 UP Diliman

Researchers; clinicians, patients-at-risks,

drug developers, Policy Makers1,170,067.20

Filipino Genome Research Program

Program aims to profile the Filipino genome

including the genome of several ethnolinguistic

groups to be used in medical and forensic

applications.

2018-2024 UP DilimanResearchers; clinicians, patients-at-risks,


The Predict-XDR Project: Predicting

genetic markers for pre-XDR and XDR

tuberculosis

To identify novel markers that predict pre-XDR

and XDRTB.2018-2024

University of the Philippines -

Manila, National Institutes of

Health - Institute of

Molecular Biology and

Biotechnology



6 of 22

Project


Original


Clinical proteomics for cancer initiative:

A proteomics-based discovery of non-

small cell lung cancer (NSCLC)

biomarkers and drug targets in the

Philippines (CIPC)

(Epidemiological and Molecular

Characterization of Respiratory

Syncytial Virus (RSV) in Children in

Southeast Asia; withdrawn Nov 2020 )

The project aims to identify potential biomarkers,

drug targets, and pathways involved in NSCLC

using proteomics.

2019-2022UP Diliman, Lung center of

the Philippines



Epidemiology of Acute and Severe

Dengue Infection through the

Integrated Analysis of Molecular,

Virologic and Clinical Factors

The project aims to conduct a longitudinal study of

dengue patients using in vitro models and

comprehensive clinical data analysis, and to

identify epidemiological, host and viral molecular

markers of dengue infection and severity for the

future development of clinical surveillance and

laboratory diagnostic guidelines and tools for the

prediction, control and management of potential

epidemics.

2019-2022 St Lukes Medical CenterResearchers; clinicians, patients-at-risks,


Cellular Immunity and Resistance to

Schistosomiasis in the Philippines

(CRISTAL)

CRISTAL will analyse cellular and antibody

responses at baseline and at follow up intervals

after treatment to correlate immune phenotype

with reinfection status. It is hypothesised that the

frequency and phenotype of follicular T helper

cells (Tfh) and follicular T regulatory cells (Tfr)

determine the antibody classes produced and

hence, a resistant or susceptible phenotype in

infected individuals. No previous studies have

investigated the role of Tfh and Tfr cells in

schistosomiasis and the new information gained

from this study will be of importance to combat

this debilitating disease in the Philippines, as it

remain a major barrier to social and economic

development. CRISTAL will provide a better

understanding of the immune response and will

inform the future development of vaccines.

2022-2024Research Institute for

Tropical Medicine (RITM)

Identification of the protective

immunological phenotype of individuals

resistant to re-infection with Schistosoma

japonicum (Sj) in the Philippines and

improvement of the sensitivity and

accuracy of diagnosis in low-intensity

settings, thereby increasing the precision

of our analysis of immune correlates of

resistance and susceptibility in this

setting.

1,954,955.33

Program: Re emerging and Emerging Diseases 60,157,696.90

Seasonal Arboviruses of Aedes

Albopictus (Diptera: Culicidae) in

Highland and Lowland Sites of Cebu

City, Philippines

Vector control policy 2021-2022 University of San CarlosDengue patients; health professionals;

Researchers; Academe; Policy Makers2,500,000.00

7 of 22

Project


Original


Program Title: Development and

Production of a Lateral Flow Rapid

Diagnostic Test to Determine Pre-

Vaccination Dengue Serostatus Among

Dengvaxia Vaccines

Project 1: Process Development of the

Dengue Anti-NS1 Rapid Diagnostic

Test

To establish the anti-NS1 ELISA using the

University of Hawaii protocol as a proof-of-

concept for the rapid test. The anti-NS1 ELISA wil

be evaluated using well characterized banked

serum samples from the Dengue National

Reference Laboratory

2019-2023 RITM DOH, Health Sectors 5,500,000.00

Autopsy Evaluations of Pathological

and Immunological Events in Fatal

Infections

Caused by Arboviruses and Emerging

Infections

This study will serve as an invaluable resource in

the conduct of objective research which can

readily be accessed by scientists and provide

robust answers backed by scientific evidence

specifically in correlating a specific pathogen (i.e.

dengue or any other arbovirus).

2019-2023 UP Manila - NIH 5,000,000.00

Dengue Communication: Discovering

Prevailing Perceptions Toward Dengue

and Dengvaxia

This proposed research will investigate both the

media content and audience reception of the

dengue issue and the Dengvaxia controversy.

2019-2022 UP Diliman 4,000,000.00

The Clinical and Demographic Profile

of Dengvaxia Vaccines with Suspected

Acute Dengue Infection

The overall objective is to assess the clinical and

demographic profile of the Dengvaxia vaccines

with suspected acute dengue infection.

2019-2022 UP Manila - NIH 2,000,000.00

Performance of a dengue anti-NS1

assay for the determination of dengue

serostatus among children in the

Philippines

To assess the sensitivity, specificity, positive

predictive value and negative predictive value of a

new dengue anti-NS1 IgG ELISA assay for the

determination of dengue serostatus in Filipino

children who received and did not receive CYD-

TDV, using neutralization test (NT) as the gold

standard.

2019-2023 NIH Dengvaxia vaccinees 10,189,334.50

Development of IoT-Based OL Trap

and Localized Dengue

Vector Surveillance for Cauayan City

The project aims to develop an IoT-based OL trap

to that will automatically transmit data to the

localized dengue

vector surveillance of Cauayan City and display

the ol index in real time.

2021-2022 Isabela State University

Community Members of the Local

Government Unit of Cauayan City,

Cauayan City Health Office Health

Workers, Officials of Local Government

Unit of Cauayan City, ASEAN neighbor

countries

4,990,000.00

Moleculo-epidemiological study of

dengue virus among livestock and

domesticated animals as potential

zoonotic reservoirs

The general objective of the study is to detect and

characterize the Dengue Virus (DENV)

serotypes that infect livestock and domestic

animals.

2021-2023 Philippine Carabao Center

General Public, Health workers and

researchers in veterinary science/

medicine

4,990,000.00

8 of 22

Project


Original


Operational platform for dengue virus

and its mosquito vectors in the

Philippines (OUTDENGUE)

Project 1: Development and Evaluation

of Machine Vision Protocols for

Identifying, Classifying, and Counting

Mosquitoes

The general objective of this research endeavor is

to develop and evaluate an MVS for identification,

classification, and counting of mosquito species.

2021-2023University of the Philippines

Los Baños

Academics and science researchers,

barangay LGUs10,000,000.00

Operational platform for dengue virus

and its mosquito vectors in the

Philippines (OUTDENGUE)

Project 2: Detection and

characterization of dengue virus

isolates from selected endemic

provinces of the Philippines:

implications to community level disease

control and prevention

Project 2 aims to describe circulating genotypes of

dengue virus in selected endemic provinces of the

Philippines and how these impact community

disease control and prevention.


Los Baños,

The Filipino people most especially

children, the local public health systems

(DOH, Provincial Health Office, Municipal

Health Office,

government hospitals and health

facilities), and the local government units

(LGUs), Scientists and other researchers

10,000,000.00

Enhancing the Country’s

Biopreparedness for COVID-19 and

Other Emerging Infectious Diseases

To develop mechanisms for rapid diagnostic kit

stockpiling in response to emerging outbreaks

and epidemics of emerging infectious diseases in

the Philippines and the region

2020 The Manila HealthTek, Inc

The Filipino patients at risk of emerging

infectious diseases (EIDs), particularly the

Corona Virus Disease-2019 (COVID-19),

Clinicians and healthcare institutions that

need rapid clinical diagnostic pathways for

EIDs, Public health institutions in need of

diagnostic tools for disease surveillance,

the health workers and researchers for

any other future applications of the results

of the different studies to be conducted.

988,362.40

The Philippine COPD Profile and

Survival Study (CPASS): A muti-center,

prospective cohort, observational study

The Philippine COPD Profile and Survival Study

will provide the necessary information, disease

trends and statistics aimed to increase the

understanding of physicians about the local

phenotypic distribution of COPD and its survival

pattern.

2017 - 2024Research Institute for

Tropical Medicine (RITM)

Patients-at-risk; Researchers; Health

Industry, Policy Makers3,000,000.00

9 of 22

Project


Original


Prospective and Urban Rural

Epidemiologic Study (PURE)

The project aims to: 1. To develop cardiovascular

risk calculators that

are appropriate for individual countries or regions;

2. To assess the

relative contributions of societal influences [as

measured by each of

the 4 domains of interest (built environment,

nutrition, policy,

psychosocial/socioeconomic factors and tobacco)

on individual lifestyle

choices (diet, activity) and on risk factor levels

(INTERHEART score)

obesity, DM and CVD (cross-sectional

component). 3. To determine if

societal changes in the above 4 domains over

time affect behaviours, and

risk factor levels.

2017 - 2024

Section of Adult Medicine

and Medical Research Unit

UP- College of Medicine

Patients-at-risk; Researchers; Health

Industry, Policy Makers3,500,000.00

Program: Functional Foods 8,000,000.00

Isolation and Characterization of

Bioactive Peptides from Coconut Fruit

(Cocos nucifera L.)

The project aims to isolate and characterize the

bioactive peptides from hydrolysates of total

soluble proteins of coconut fruit (Cocos nucifera

L.)

2021-2024 ISUScientific Community; Pharmaceutical and

Medical Services3,000,000.00

24K Liquid Gold: Enhancing the

Functional Food Properties of Spray-

dried Turmeric Extracts using

Curcumin and Turmerin as Standards

Develop a spray-dried water-soluble turmeric

extract for use in the commercial production of

functional foods.

2019-2024 HerbanextFilipino consumers, turmeric farmers,

academe5,000,000.00

The effects of dietary fiber and other

non-digestible carbohydrates in a pre-

identified low glycemic index rice and

stabilized brown rice on gut microbiota

To determine the effect of non-digestible

carbohydrates on the human gut microbiota

composition and on the glycemic response with

the consumption of the pre-identified low-

glycemic index (GI) rice in its well-milled (WM)

and undermilled (UM) forms, and the stabilized

brown rice (SBR)

2020-2024 FNRIAcademe, researchers, technopreneurs,

MSMEs, rice growers4 ,950,392.00

Program:Nutrition and food safety 1,500,000.00

Utilization of Buffalo (Bubalus bubalis)

Kesong Puti Whey By-products as a

Potential Source of High Value Food

Supplement and Elucidating its Growth-

Promoting Effects in Stunting

Utilize Buffalo (Bubalus bubalis) Kesong Puti

Whey by-products as a Potential Source of High

Value Food Supplement and to elucidate its

Growth- Promoting Effects in Stunting

2019-2024 Institute of Chemistry, UPLBAcademe, research institutions,

technopreneurs, general public1,500,000.00

Program: Mental Health 23,196,639.39

10 of 22

Project


Original


Patterns of detection and treatment of

mental and behavioral disorders

among Overseas Filipino Workers

(OFWs): Implications to Psychosocial

Support Services

To analyze the patterns of detection and

treatment of mental and behavioral disorders

among Overseas Filipino Workers and derive

from the findings the implications to psychosocial

support services

2020-2021University of Asia and the

PacificOFW, policy makers 1,500,000.00

Development of a Standardized Stigma

and Discrimination Index for Filipino

Patients

1. To review the current current disease stigma

and discrimantion index in the literature

2. To identify the individual and socio-cultural

factors influencing the disease stigma and

discrimination among Filipinos

3. To design a disease stigma and discrimination

index contextualized in the Philippine culture

4. To test the validity and reliability of the disease

stigma and discrimination index developed among

the following persons living with the following

disease conditions: (1) tuberculosis, (2) leprosy

and skin diseases, (3) physical disabilities, (4)

cancer, (5) mental illness, (6) HIV and other

sexually transmitted infections, (7) hepatitis, and

(8) obesity.

2020-2024 St. Paul University Manila Healthcare providers 7,178,679.40

Psychosocial Interventions Used by

Mental Health Professionals among In-

Patients in Cardinal Santos Medical

Center

1. To determine psychosocial interventions used

by mental health care providers

among in-patients of Cardinal Santos Medical

Center referred for psychosocial

problems.

2. To determine psychosocial interventions used

by mental health care providers

among in-patients of collaborating hospitals

referred for psychosocial problems.

2019-2024Cardinal Santos Medical

Center

Clinicians, mental health service users,

policy makers 3,383,471.88

Understanding the Social Determinants

of Mental Health in the Philippine

Context

To contribute to the understanding of social

determinants of mental health in the Philippines

and to build to knowledge base on the

psychosocial impact of the COVID 19 pandemic

on Filipinos

2021World Association for

Psychosocial Rehabilitation

Clinicians, mental health service users,

policy makers 1,646,953.75

Acceptability of Telepsychiatry among

Overseas Filipino Workers in Kuwait

To determine the acceptability of Telepsychiatry

consultation among Overseas Filipino Workers

(OFW) in Kuwait OWWA facility within the 12-

month period (3 months software development, 9

months telepsychiatry assessment)

2021Southern Philippines Medical

CenterOFWs, clinicians, policy makers 5,265,182.04

Promoting Self-care among Health and

Social Welfare Professionals of the

City Government of San Fernando,

Pampanga: Development of an

Employee Wellness Program using the

PRECEDE-PROCEED model

To develop a mental health and wellness program

plan for the health and social welfare

employees of the local government unit of the City

of San Fernando, Pampanga.

2021-2022Angeles University

Foundation

Employees from the city health and city

social welfare and development offices of

the local government of the City of San

Fernando,

Pampanga

2,695,257.20

11 of 22

Project


Original


Assessment of the Effects of the

COVID-19 Pandemic on the Mental

Health of Frontline Health Care

Workers

The study aims to assess the mental health

outcomes of healthcare workers, particularly

depressive symptoms,

anxiety, and stress during the COVID-19

Pandemic in the Philippines

2020-2021ACCESS Health

Internationalpolicy-makers 1,527,095.12

Program: Other Health Priority Areas (OPA) 14,500,000.00

The International Polycap Study 3

(TIPS 3)

Polycap-to determine whether the Polycap

reduces the risk of the composite outcome of

major CVD, plus heart failure, resuscitated cardiac

arrest, coronary verascularization with objective

evidence of ischemia compared to placebo;

Aspirin - to determine whether aspirin reduces the

risk composite outcome of CV events of ischemia

compared to its placebo and ; Vitamin D - to

determine whether Vit D reduces the risk of

fractures compared to its placebo.

2017 - 2022

Section of Adult Medicine

and Medical Research Unit

UP- College of Medicine

Patients with underlying atherosclerosis,

Elderly people aged 50yrs old and above,

Health industry, Policy makers

3,500,000.00

Heparin Anticoagulation to Improve

Outcomes in septic shock: The HALO

International Phase II RCT

2019-2022

Foundation for the

Advancement of Clinical

Epidemiology, Inc.



Profiling the Different Vasculitides in

the Philippines

To characterize the clinical profile of primary

vasculitides among adult Filipinos and dentify the

perceived challenges encountered by clinicians

handling adult patients with primary vasculitides

2020-2022University of the Philippines,

College of Medicine Patients, Doctors 8,000,000.00

Program: ICT in Health 35,196,801.16

Roll-out of RxBox Telehealth Device in

Selected Health Facilities in the

Philippines

To deploy RxBox units to selected rural health

centers in the Philippines 2015 - 2021 DOST Regional Office 4-A

General population; Researchers;

Academe; Health professisonals; Health

Industry; LGUs; Policy makers

19,496,801.16

Documentation of Traditional

Knowledge and Practices on Health

and Development of Digital library on

Health: Kankanaey and Ifiallig

communities in Benguet and Mountain

province

To provide protection to the traditional knowledge

of Indigeneous People (Ips), facilitate biodiversity

conservation and has a potential to provide

scholarly information for the research community,

policymakers, and the general public.

2019-2024 Benguet State University Indigenous people, researchers, academe 1,000,000.00

Documentation of Philippine Traditional


and Development of Traditional

Knowledge Digital Lirary on Health:

Higaonon Tribe of Esperanza, Agusan

del Sur






2019-2024Philippine Normal University -

MindanaoIndigenous people, researchers, academe 1,500,000.00




Knowledge Digital Library on Health:

Mamanwa of Surigao del Norte






2019-2024

Surigao State College of

Technology / St. Paul

University Surigao

Indigenous people, researchers, academe 1,500,000.00

12 of 22

Project


Original


Documentation of the Traditional

Knowledge on the Ethno Medicinal

Practices of the MANOBO Community

in San Miguel, Surigao del Sur






2019-2024Surigao Del Sur State

University - Main CampusIndigenous people, researchers, academe 1,500,000.00

Documentation of the Traditional

Knowledge on the Ethno Medicinal

Practices of the RAJAH

KABUNGSUAN MANOBO Community

in Lingig, Surigao del Sur







University - Tagbina CampusIndigenous people, researchers, academe 1,500,000.00





Selected Kamayo Communities of

Lianga Bay Municipality of Surigao del

Norte






2018-2023

Surigao State College of

Technology / St. Paul

University Surigao

Indigenous people, researchers, academe 1,500,000.00




Knowledge Digital Library on Health of

Butuanon in Butuan City

Project aims to document the traditional

knowledge and practices on health, disease and

healing of Butuanon, to preserve the traditional

knowledge and practices in a digital library from

represented in www.tkdlph.com, and to translate

the outputs of the research into

activities/initiatives/papers that will benefit the

community and other interested sectors.

2018-2023 Caraga State University Indigenous people, researchers, academe 1,500,000.00





Folk Healing Practices of Surigaonon in

Surigao del Norte

Project aims to document the traditional


healing of Surigaonon in Surigao del Norte, to

preserve the traditional knowledge and practices

in a digital library from represented in

www.tkdlph.com, and to translate the outputs of

the research into activities/initiatives/papers that

will benefit the community and other interested

sectors.

2018-2023Surigao State College of

TechnologyIndigenous people, researchers, academe 1,500,000.00


Knowledge and Practices: The

Tandaganons in Surigao Del Sur

The project aims to document the traditional


healing of the Selected Barangays/Communities

of Tandaganon, in the Municipality of Tandag

City, Surigao del Sur, to preserve the traditional

knowledge and practices in a digital library from

represented in www.tkdlph.com, and to translate

the outputs of the research into

activities/initiatives/papers that will benefit the

community and other interested sectors.


University - Tandag CampusIndigenous people, researchers, academe 1,500,000.00

13 of 22

Project


Original


Documentation of Traditional

Knowledge and Healing Practices of

Dinagatnons, Province of Dinagat

Islands (PDI), Caraga, Philippines

To contribute to the national repository of

traditonal knowledge and practices on health,

facilitate biodiversity conservation and has a

potential to provide scholarly information for the

research community, policymakers, and the

general public.

2019-2024 St. Paul University SurigaoCultural communities, researchers,

academe 1,200,000.00

Documentation of Philippine traditional

knowledge and practices on health and

development of traditional knowledge

digital library on health: selected

cultural communities of Romblon






2018-2024 Romblon State University Indigenous people, researchers, academe 1,500,000.00

BIOMEDICAL ENGINEERING FOR HEALTH TECHNOLOGIES 60,000,000.00

Development and Technical and

Clinical Safety and Performance

Testing of a Philippine-made Volume-

cycled Mechanical Ventilator

to design a cheap but safe and reliable

mechanical ventilator for respiratory failure

support, to do bench testing of this ventilator in

terms of material failure, response rates, and

other variables for bench testing on lung models

and anesthesized dogs ,

2017 -2022

UP College of Medicine, De

La Salle University, Mapua

Institute of Technology

hospitals; patients; health industry, 30,000,000.00

A Robotic Exoskeleton Arm for Upper-

extremity Rehabilitation

Aims to develop a robotic exoskeleton arm that

specifically addresses the upper-extremity

rehabilitation of stroke patients.

2017 - 2022 De La Salle UniversityRehabilitation medicine healthcare

providers, patients, rehabilitation centers5,000,000.00

Development of an Insole Pressure

System in the Prevention of Foot

Ulcers in Diabetes Mellitus

To develop a wireless, wearable, self-monitoring

device using pressure sensors and alarm systems2018-2022 UST

Researchers; health professionals;

hospitals; patients5,000,000.00

Philippine Biomed Hub

To facilitate and promote biomedical device

innovation research activities and establish a

research center on biomedical device innovation.

2018-2022DLSU, PBDIC member

institutions



Philippine Bioengineering Institute

Program, Project 1. Tayo Project:

Robotic Exoskeleton for Lower Limb

Rehabilitation

To facilitate and promote biomedical device

innovation research activities and establish a

research center on biomedical device innovation.

2018-2021DLSU, PBDIC member

institutions



TAYÔ Project - Robotic Rehabilitation

for the Trunk and Lower Extremity:

PHASE 2 – Safety Testing and

Formulation of Clinical Trial Protocol

To develop TAYO device for robotic rehabilitation 2020-2024DLSU, PBDIC member

institutions



LAPARA Project: Robotic Articulating

Laparoscopic Instrument Phase II

The general objective of this project is to design,

fabricate and evaluate a cost-effective robotic

surgical system.

2020-2022Researchers; health professionals;


14 of 22

Project


Original


Design and Development of a Portable

Multi-Sensor System for Sweat Studies

To a develop a wearable microfluidic patch and

sensing electronics and wireless capability that

aims to provide analyte measurements in sweat

such as glucose, lactate, potassium and sodium

as well as sweat rate and temperature; and also,

to establish the correlation and conversion factor

between sweat and blood analytes.

2020-2022

University of Sto. Tomas

(UST)

Athletes, Sports Enthusiasts;


hospitals; patients

5,000,000.00

Program: Climate Change and Disaster Risk Reduction 46,144,324.19

S&T Innovations to improve health

services during disasters

S&T based tools which improve health services

during disasters

2021-2024 1,000,000.00

Researches to ensure health

consequences during disasters are

reduced

Tools or inventions to ensure reduced health

consequences brought about by environmental

contamination or pollution 2021-2024 1,000,000.00

Climate Change Adaptation in Health

Generated data on the characterization climate

change sensitive diseases for possible

intervention development

2021-2024 1,000,000.00

Determining Provincial Health Risk to

Climate and Disasters in the Philippines

The results of this project can be used for

improving disease surveillance, prioritizing more

vulnerable provinces in the National Climate

Change Action Plan, and developing co-benefits

interventions for Climate Change and Health.

2021-2024 EpiMetrics, Inc.

Provincial Governments involved in the

study, DOH, DENR,Climate Change

Commission,scientific research

community interested in disease

modelling, spatial and planetary health,

population residing in the study sites

3,930,927.96

Developing a Geographic Information

System to Address Post-Disaster Basic and

Health Needs in Temporary Housing

Facilities

The results of this project will provide information

of health needs and corresponding geographical

information to facilitate more efficient distribution

of life-saving aid, as well as identify logistical

patterns of need. This will also provide LGUs, the

regional and national government, as well as

those donating aid, with the information they need

to ensure the efficient and effective uptake of

goods and services.

2021-2022 EpiMetrics, Inc.

Disaster response, decision-makers in the

participating LGUs, LDRRMC,

IDPs,scientific research community

interested in DRRM and in developing and

using GIS

4,633,620.97

Development of IKSP-Based Technologies

for Disaster Risk Reduction and Health

Emergencies: The Ayta and Dumagat

Climate Change Resilience as Models

This project will serve as a baseline study and

instrument to be used in assessing climate

change resiliency of indigenous people as based

on their IKSPs.

2021Addictus Research and

Intervention Center

IP partcipants, IP leaders/elders,

NCIP,Climate Change Commission,

NDRRMC & LDRRMC,LGU, DOH, and

others (NGOs, POs, etc.)

4,866,034.80

15 of 22

Project


Original


Seasonal distribution and allergenicity of

airborne pollen in Metro Manila, Ilocos Norte

and Leyte, Philippines

The results generated by this project will be

utilized in educating the public on allergies and its

possible causes and plant sources of pollen

allergens that may affect their health. In

addition, it will develop technologies for public use

that will forecast airborne pollenconcentrations

and will be valuable for the accurate diagnosis

and preventive measures of

pollen allergy.

2021-2024 University of Santo Tomas

Clinicians such as Pulmonologist,

Allergologist and other related clinical

practitioners involved in upper respiratory

track infections, patients with allergies,

hospital and clinical lab. doing allergy

screening, researchers involved in pollen

and allergy research,

entrepreneurs/business people interested

in commercializing potential products

3,713,740.46

DEVELOPMENT OF HEALTH INDEX

AND VULNERABILITY REDUCTION

SYSTEM FOR REGION 4B (D-HIVE

4B)

To develop HVI for MIMAROPA coupled with an

emergency response system. 2020-2024 Mapua University

Community population, LGUs,

Government agencies involved in DRRM 15,000,000.00

R&D for Disaster Risk Reduction and

Climate Change Adaptation

to fund and implement cross cutting researches

under health research area which have direct

implications on the public health

2017 - 2024

ADMU; DLSU; Remote Area

Medical (Cuyo Foundation,

Inc.); Symmetrix Research

Consultancy; Regional

Health Research and

Development Consortia

General population; Researchers; LGUs;

Policy makers 5,000,000.00

Establishment of the Global Hub on

S&T Innovations in DRR and Climate

Change Adaptation

to develop the Philippines as the global Hub on

S&T innovations for disaster risk reduction and

climate change adaptation (health)

2017 - 2024General population; Researchers; LGUs;

Policy makers 3,000,000.00

Researches to ensure health

consequences during disasters are

reduced

Tools or inventions to ensure reduced health

consequences brought about by environmental

contamination or pollution 2021-2023 2,000,000.00

Climate Change Adaptation in Health

Generated data on the characterization climate

change sensitive diseases for possible

intervention development

2021-2023 1,000,000.00

Program: Capacity Building and Development of Human Raesource in S&T 117,345,030.90

Developing Capacity to Implement

Health Research

addition, it will develop technologies for public use

that will forecast airborne pollen2017 - 2025

DOST Regional Offices in

17 Regions; De La Salle

University-Dasmariñas for

Region 4A and UP-NIH for

NCR

Health Sector, Researchers, Research

Institutions, Medical schools and

academic institutions

52,023,873.50

MD-PhD Molecular Medicine

Scholarship Program

concentrations and will be valuable for the

accurate diagnosis and preventive measures of2017 - 2025

University of the Philippines,

Manila - College of Medicine

Health Sector, hospitals, medical

laboratories, 43,700,600.00

MS Molecular Medicine Scholarship

Programpollen allergy. 2017 - 2025 SLMC College of Medicine


laboratoties2,500,000.00

Clinical Research Fellowship ProgramTo produce clinical research experts in

Hepatology, infectious disease, natural products2017 - 2025 PCHRD


laboratories, medical practitioners 3,058,000.00

16 of 22

Project


Original


PNHRS R&D Capacity Building

Program

In support of the administration’s goal to promote

countryside development, DOST-PCHRD through

IDD aims to capacitate all 17 regions in Health

R&D by establishing regional training centers

where all capacity building initiatives of the

Council will be conducted

2019 - 2025 PCHRDHealth Sector, hospitals, medical

laboratories, medical practitioners16,062,557.40

Other S&T Program 91,603,404.84

Regional / Institutional databases,

information systems and websites

(HERDIN/ PHRR, eHealth portal,

RHRDC websites, etc)

Researchers, Community, Policy Maker 5,000,000.00

Health S&T Publishing an other

research dissemination activitiesResearchers, Community, Policy Maker 7,500,000.00

Support to Research Dissemination Researchers, Community, Policy Maker 5,000,000.00

Research to Policy Translation

workshopsResearchers, Community, Policy Maker 2,000,000.00

3-Minute Pitch to Policymakers

competitionResearchers, Community, Policy Maker 500,000.00

IPTM Services-IPRotecH Researchers, Community, Policy Maker 2,000,000.00

IPTM Services- Capacity Building 1,500,000.00

IPTM Services- Assistance to start-ups

and start-up enablers Researchers, Community, Policy Maker 20,000,000.00

IPTM Services - Research Translation

to Product 2,000,000.00

Human Resource Development

Program (HRDP)Researchers, Community, Policy Maker 2,000,000.00

Health S&T Institutional Activities Researchers, Community, Policy Maker 28,103,404.84

Implementation of the Philippine

National Health Research System

(PNHRS)

To come up with a coordinated, and coherent

research agenda which connect to, and converge

with, the wider health, economic, political,

education and S&T systems of the country.

2017 - 2025 PCHRD, DOH, UP-NIH Researchers, Community, Policy Maker 8,000,000.00

Ethics

(Ethics R&D Program)

Focuses on studying comparable standards and

ethics review procedures in countries with

systems or practices that can serve as models for

further improvemen

2018 - 2025 PCHRD RECs, researchers, research participants 8,000,000.00

Program: Collaboration with

Industry, Academe and International

Institutions

24,500,000.00

ASEAN Network for Drugs,

Diagnostics, Vaccines, and Traditional

Medicines Innovation (ASEAN-NDI)

The ASEAN-NDI was established to ensure that

health technology development and the capacity

of member states are appropriately maximized

and managed according to regional health needs.

Policy makers, planners, health advocate,

medical communities, health S&T

Networks, Researchers, General Public

3,000,000.00

2017-2024 PCHRD

Enhancement and maintenance of databases,

information systems, and websites

PCHRD dissemination and promotional activities

2018-2025PCHRD, DOH, SUCs,

Regional Offices

17 of 22

Project


Original


e-ASIA Joint Research Program

The e-ASIA JRP aimed to present a research

collaboration opportunity for researchers, as it

offers access to funding and other resources to

support multi-investigator research engaging

scientists in the participating countries from Asian,

Pacific, Europe and US.

Policy makers, planners, health advocate,

medical communities, health S&T

Networks, Researchers, General Public

5,000,000.00

Harvard Medical School

International Linkages French National Institute of Health and Medical

Research (INSERM)2017-2025 5,000,000.00

Community - Approach to Control and

Halt Drug - Resistant TB (COACH

DRTB)

The study aims to investigate the effectiveness of

COACH-DRTB strategy in the detection and

treatment of DRTB; treatment success rate

among the active DRTB cases after completion of

treatment; relapse rate of treated patients

observed 2 years porst treatment; incidence of

active TB diseases among household contacts of

patients with DRTB observed within 2 years; and

factors associated with positive outcomes (cured,

treatment completed)

2018-2025 DLSHSIResearchers, Health Industry, Policy

Makers 6.702,557.00

Surveillance Integrating Phylogenetics

and Epidemiology for Elimination of

Disease: Evaluation of Rabies Control

in the Philippines (SPEEDIER)

This study will develop and implement a cost-

effective, epidemiologically robust, enhanced

surveillance and response package to guide and

sustain elimination of rabies in the Philippines.

2018-2021 FETPAFIResearchers; clinicians, patients-at-risks,

drug developers, Policy Makers 2,000,000.00

Cellular immunity and resistance to

schistosomiasis in the Philippines

This study will assess the role of immune cells in

resistance or susceptibility to Schistosoma

japonicum reinfection in the Philippines before

and after treatment with Praziquantel.

2019-2022 RITMResearchers; clinicians, patients-at-risks,


Using Host-Responses and Pathogen

Genomics to Improve Diagnostics for

Tuberculosis in the Philippines

This study will develop a TB human blood

transcriptome response assay risk score that

could be used to identify active TB and evaluate

treatment response in reducing active TB.

2019-2022 RITMResearchers; clinicians, patients-at-risks,


ZooTRIP. Zoonotic transmission of

intestinal parasites: implications for

control and elimination

This project aims to assess the contribution of

zoonotic transmission and environmental

reservoirs to the burden of human intestinal

helminth infection in the Philippines, and

determine the most effective knowledge-led

strategies for helminth control and elimination in

endemic areas.

2019-2022 UPLBResearchers; clinicians, patients-at-risks,


Affordable near-patient diagnostics to

distinguish

infectious diseases in the Philippines

(AND2ID in Ph)

This project aims to provide an evaluation of the

impact of affordable early diagnosis on the patient

pathway of infectious disease in the Philippines

using dengue and leptospirosis as models,

through providing a route to low cost nucleic acid

tests (NATs) in the Philippines with global

purchasing price parity.

2019-2022 USTResearchers; clinicians, patients-at-risks,


2017-2024 PCHRD

18 of 22

Project


Original


The UK-Philippines Remote Retinal

Evaluation Collaboration in Health:

Diabetic Retinopathy (REACH-DR)

This project aims to establish a Diabetic

Retinopathy (DR) telemedicine screening

programme in the Philippines.

2019-2022 UPMResearchers; clinicians, patients-at-risks,


COVID-19 Research Program 157,119,884.63

SaniPod: Self-Contained Disinfecting

Cubicle

To design and fabricate a cost-effective self-

containing low-level disinfection cubicle and test

the prototype in entry/exit areas for healthcare

workers


Manila

1. Healthcare workers working in COVID-

19 dense areas in the hospital.

2. COVID-19 referral hospitals and

hospitals handling COVID-19 suspect and

confirmed cases.

3. Government agencies and private

hospitals that will purchase the self-

containing cubicle units for use.

4. Non-hospital settings in the different

areas of the country where there is

anticipated increased traffic flow or

congregation of people whether in times

of peace or crisis, thus increasing chance

of contamination and infection.

5. Job opportunities for Filipinos in the

production of cubicles

5,000,000.00

miPCR: Development of a Microfluidic

Miniaturised PCR Device (miPCR) for

SARS-Cov-2 RNA Amplification via

FDA-approved COVID-19 RT-PCR kits

The project is proposing the accelerated

development of a cost-effective, scalably

manufactured and readily deployable nucleic acid

amplification test (NAAT) platform using FDA-

approved qPCR test kit reagents (e.g. the UP

COVID-19 kit) to enable expanded COVID-19

testing and primary screening.

2020-2024 Ateneo De Manila University

1. Primary care centers

2. Subnational laboratories

3. Designated COVID-19 Hospitals

4. For Public and Private Healthcare

Diagnostic Laboratories

5. Primary and Secondary Hospitals

6. Epidemiology Surveillance units in local

government

7. Pharmaceutical companies

8. DOH/Local Government/Private

Hospitals

5,000,000.00

SIBOL: CleanIntubate: Laryngoscope

Blade Disinfection Device

The proposal aims to design portable device that

will automatically cleanse, disinfect, wash and dry

laryngoscopes, that is faster and will lessen the

chances for disease transmission. The device can

be easily transported from one area of the

hospital to another.


Manila





confirmed cases

5,000,000.00

19 of 22

Project


Original


SIBOL Personal Protective Equipment

– Design and Development of Locally-

Manufactured, Reusable, Powered, Air-

Purifying Respirator (PAPR)

To design an innovative powered, air-purifying

respirator (PAPR) for chemical and biological

protection, to develop a reusable prototype

compliant to NIOSH standards, to formulate a

business model for commercialization, and to

activate the supply chain towards the production

and testing of PAPR


Manila

1. 127 Healthcare workers in one (1)

Covid Referral Center.

2. 30 Laboratory Technicians in one (1)

Covid Referral Center.

3. Possibly extend the assistance to the

Bureau of Fire Protection (BFP),

Philippine National Police (PNP) and the

Military.

5,000,000.00

SIBOL CoVID PPE- Reusable Face

Mask Employing Biodegradable Non-

Woven Nanofibers Membrane

Project's aims is the immediate deployment of

reusable face masks employing biodegradable

non-woven nanofiber filters, which are thought to

have the capability to filter out pathogens of

submicron sizes, like SARS-COV2.


Diliman

policy makers; patients; Health workers;

researchers; filipino people5,000,000.00

ADDS: Development of an amplified

DNA detection system (ADDS) for the

detection of SARS-Cov-2 based on the

thermocycler output of FDA-approved

COVID-19 RT-PCR kits

The project is proposing the accelerated

development of a cost-effective device & kit for

expanded COVID-19 testing and primary

screening by enabling conventional thermocyclers

to be used with FDA-approved qPCR test kit

reagents (e.g. the UP COVID-19 kit) in order to

expand deployment of qPCR kits without the need

to also purchase and become trained in the use of

an integrated qPCR reader.



2. The five (5) subnational laboratories






government



Hospitals

5,000,000.00

‘SWIFTeR’: A focused study to validate

a streamlined COVID-19 testing

technology (for approval)

To validate one or more related isothermal

amplification and detection methods for use,

ideally with saliva as the matrix thereby removing

the need for slow and costly RT-qPCR

thermocycling infrastructure.

To validate one or more isothermal methods using

a protocol that requires no/minimal RNA

extraction steps.

To demonstrate the potential of these process

improvements to enable the Philippines to safely

and efficiently move progressively towards at-or-

near point of care testing for COVID and related

pathogens.



2. Subnational laboratories






government



Hospitals

5,000,000.00

Clinical Trials of Vaccines

The project is proposing the long-term evaluation

of the effects of the vaccines in the Solidarity

Vaccine Trials .

2020-2024 UP Manila1. Vaccinees of the Solidarity Trials

2. Clinical Researchers41,320,000.00

20 of 22

Project


Original


Validation Study of A Locally-

Developed Electronic Stethoscope

Prototype “E-Steth” Using A Phantom-

Based Simulation System in the

Auscultation of Lung Sounds

primary objective; designing and fabricating a low-

cost acoustic-electronic stethoscope with modular

capabilities using locally available materials that

enables physically-distanced auscultation

intended for healthcare workers wearing hazmat

suits.


Manila





confirmed cases

2,000,000.00

SIBOL Fabrication and

Characterization of UV and Hydrogen

Peroxide Vaporization for Disinfection

of N95 Respirators

The project aims to fabricate and characterize

UVGI and HPV for the disinfection and

decontamination of N95 filtration facepiece

respirators. The project offers a timely and

immediate solution by developing a portable

device that can be used at healthcare centers and

hospitals who cannot afford the expensive

sterilization or disinfection of masks. This project

may provide innovations in response to shortage

of facemask supplies amidst the ongoing

pandemic infectious disease, COVID-19, in the

country.


Manila





confirmed cases

2,000,000.00

Repurposing of Existing Drugs,

Supplements and other Formulations6,000,000.00

COVID Behaviours (i.e. Spread,

Transmission, Contact, etc.)10,000,000.00

Diagnostics and Kit Validation Studies 20,000,000.00

AI/ICT-Driven Models and Prediction

Studies

Research involves studies for the application of

AI/ICT for the monitoring, surveillance, and

prediction for COVID-19. It will also include

studies on telemedicine for remote consultation,

and for monitoring and communicating with

patients being treated for COVID-19 to improve

patient outcomes and at the same time decrease

risk of exposure of health care workers.

5,000,000.00

Personal Protective Equipment (PPE)

Research and Development10,000,000.00

Facility, Laboratory, and Hospital

Equipment Enhancement10,000,000.00

Regulatory Studies 5,000,000.00

Durability and Extent of Protection of

SARS-CoV-2 Antibodies Among

Patients with COVID-19

determine the level of SARS-COV-2 antibodies

through time among those who were previously

infected with SARS-COV-2

2021-2022Department of Pediatrics,

UP-PGH

policy makers (for returning to workplace

and relaxing social distancing measures;

filipino people

10,799,884.63

21 of 22

Project


Original


*Balik Scientist Program (Health

Sector)

Encourages Filipino scientists, technologists, and

experts to

return to the country and share their expertise for

the country's

scientific, agro-industrial, and economic

development, including the

development of our human capital in science,

technology and innovation.

2021-2024 PCHRD

Government agency, public or private,

academic institution or locally-registered

enterprise

28,370,000.00

TOTAL GIA 874,572,000.00

*Previously under DOST-Osec

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Documents

Philippine Council for Health Research and Development