Phone: DrHuggins.com Visit our website! email@drhuggins ......2012/11/15 · Decomposition of Organo-Mercury Compounds – A Review. Neth. J Agric. Aci. 24, 79-97, 1976. Schionning,

Many people have been told their health problems are all in their head because their symptoms or diseases have no medically known cause or treatment. Dr. Huggins has discovered that dental toxicity due to mercury in amalgam fillings is the cause of many of these unexplained diseases and symptoms. Other standard dental practices such as root canals have also been shown to contribute to many health issues that the medical community has no explanation for.

There is Hope!

HUGGINS Applied Healing 5082 List Dr Colorado Springs, CO 80919 Phone: 1-866-948-4638 DrHuggins.com E-mail: [email protected]

Creating Positive Health Alternatives

Visit our website!

Www.DrHuggins.com

I m p o r t a n t i n f o r m a t i o n o n D e n t a l M a t e r i a l s a n d S e q u e n t i a l R e m o v a l

Call us toll-free today! 1-866-948-4638

Balanced Chemistry

For Better Health

Are Dental Materials Toxic?

The Truth:

• Many unexplained symptoms are related to dental mercury and root canals.

• Many diseases of unknown origin are related to dental mercury and root canals. Mercury fillings cause negative blood chemistry shifts.

• Typical mercury damage sites have now been identified

• There are other dental toxins.

Help is available!

Hal A Huggins, DDS, MS 1-866-948-4638


“Research Reports”

Balanced Chemistry

For Better Health

Autoimmune diseases can be stopped and many times reversed by a Dr. Huggins’ Protocol involving neutralizing reactions to dental materials.

What is an autoimmune disease? One in which your body’s immune white blood cells destroy your own body’s tissue cells. Examples of autoimmune nervous diseases are Multiple sclerosis, Amyotrophic lateral sclerosis, Alzheimer’s, Lupus, Leukemia, Diabetes and seizures. Examples of hormonal autoimmune problems are diabetes, Hashimoto’s thyroiditis and infertility.

What creates the mistaken identity o f ce l ls as initiated from dental materials is the formation of a “Hapten”. A Hapten is a normal cell that acquires a hitch-hiker that alters the cells “self” i d e n t i f i c a t i o n code.

In this picture, mercury, as from a common dental silver-mercury filling (about 50% mercury), is shown attaching itself to a normal cell. The new cell - called the Hapten – is mistaken by the immune system as being a foreign cell

Good news!

“Hapten”

Page 2


Hal A. Huggins DDS, MS Dr. Hal A Huggins has been a cutting edge researcher in dental toxicity since 1973. Why cutting edge? Because he follows changes in immune reactivity relative to sensitivities to dental toxins—and reports them. He uses blood chemistry evaluations to determine what dental

materials and supplements are “naughty” and which are “nice”. This upsets a great financial institution that has had a low key white knight reputation for over 100 years. What are the consequences of his observations? Exposure of massive liability. Resulting in lie-ability. Greater liability than Enron. Greater than the tobacco fiasco. Who does it affect? Most everyone. Probably you.

He is presenting the observations of the last 37 of his 43 years of practice. These comments are connections he has seen between dental materials and incurable diseases. He has lectured professionally 1400 days in 46 of the U.S. states and 13 other countries. He has authored several books, written over 50 articles, and given over 1000 radio/ TV interviews.

He received a post-doc Master’s at the University of Colorado with emphasis on immunology/toxicology. He successfully pioneered treatments for autoimmune diseases due to dental toxins and has personally treated over 2500 toxic patients.

Which dental materials are implicated? Mercury, nickel, beryllium, copper, and toxins formed in dead or root canal teeth as well as in cavitations.

Page 15

1-866-948-4638

Nylander, M, Friberg, L. and Lind, V., Mercury concentrations in the human brain and kidneys in relation to exposure from dental amalgam fillings. Swedish Dental J 11: 179-187, 1987.

Friberg, Lars, Nordberg, Gunnar F. and Vouk, Velimir B. (eds.), Handbook on the Toxicology of Metals, Vol. I. Elsesvier Science Publishing Co., New York, NY, 1986.

Aschner, M., et al., Mercury Neurotoxicity: Mechanisms of blood brain barrier transport. Neuroscience and Bio-behavioral Reviews, Vol. 14, 1990.

Canton, O. and Costa, M., Correlations of DNA strand breaks and their repair with cell survival, following acute exposure to mercury and X-rays. Molecular Pharmacology 24: 84-89, 1983.

Lexmond, T.M., et al., On the Methylation of Inorganic Mercury and the Decomposition of Organo-Mercury Compounds – A Review. Neth. J Agric. Aci. 24, 79-97, 1976.

Schionning, J. D., et al., Ultra-structural localization of mercury in rat dorsal root gan-glia after exposure to mercury vapor. Progress in Histo- and Cytochemistry, Vol 23, 1990.

Konetzka, W., Microbiology of metal transformation. Micro-organisms and Minerals, 317-342, 1977

Rustam, H., et al., Arch. Environ. Health, 30: 190-195, 1975.

Swartzendruber, D. E., Adverse Immunomodulatory effects of heavy metals in den-tal materials. Proceedings from the International Conference on Biocompatibility of Materials, 1988.

References Cont...

Page 14


Mercury from fillings can also create many common symptoms of “unknown” origin. Most commonly seen are symptoms of depression, anxiety, chronic fatigue, chronic headaches, digestive upsets and memory problems. These come from one or more of the three forms of mercury that can be created from the surface of “amalgam” fillings.

Mercury vapor effecting the:

• Optic nerve (Ganser ‘85)

• Nasal sinus (Henricksson ‘98)

• Lungs (Sjostrand ‘70)

• Blood Brain Barrier (Nylander ‘87)

Examples of results of exposure to each form include:

The three forms of mercury (called the 3 costumes of mercury) are:

1.) The vapor form - as it usually comes off from the filling (Chew, ‘91; Svare ‘81; Wataha ‘91)

2.) The ionic mercury form - also from the surface of the filling (Heintze ‘83)

3.) The methyl mercury form - formed by bacteria in the

mouth and in the intestinal tract. (Compeau ‘84; Wood ‘74)

Page 3

1-866-948-4638

As a result of treating thousands of patients, Dr. Huggins can demonstrate that dental materials control a person’s immune system. He showed examples of how high white blood cells can be reduced and low white blood cells increased by the same Protocol. (See figures I and II on page 5)

Immune Dysfunction

Ionic mercury effecting:

• Acute intracellular destruction (Friberg ‘86)

• Creation of “leaky membranes” (Friberg ‘86)

• Energy interference blocking Na-K pump (Aschner ‘90)

• Alters DNA (Canton and Costa ‘83)

• Creates neurotoxicity (Aschner ‘90)

Methyl Mercury effecting:

• Lipid soluble insidious poison (Lexmond ‘76)

• Endocrine disturbances (Friberg ‘86)

• Development of sensory neuropathy (Schionning ‘90)

• Plasmids convert ionic to methyl mercury (Konetzka ‘77)

• Muscle weakness (Rustam ‘75)

• Formation of haptens (Swartzendruber ‘88)

Page 4


“Dental

materials

control a

person’s

immune

system…”

These sympathetic hormones create a premature degeneration removal of tissues that are not really at the end of their life span - but there is no regeneration action to fill the vacancy. Thus, a new disease is created.

When fillings are removed sequentially, that is, with the negative fillings replaced first, the opposite scenarios takes place. As negative fillings are removed, a potassium efflux occurs at the synapse calling for an increase in parasympathetic hormones (parathyroid, insulin, posterior pituitary and estrogen). The result is to stimulate healing.

References Chew, C. L., et al., Long-term dissolution of mercury from a non-mercury re-leasing amalgam. Clin Rev Dent, 13 (3): 5-7, 1991.

Svare, C. W., et al., The effect of dental amalgams on mercury levels in expired air. J Dental Res 50: Sept 1981.

Wataha, J. C. and Craig R. G., The release of elements of dental casting alloys into cell culture medium. J Dent Research 70: 1014-1018, 1991.

Compeau, G. and Bartha, R., Methylation and demethylation of mercury under controlled redox, pH and salinity conditions. Applied & Envion Microbiol, Vol 38, No 6, 1203-1207, 1984. Wood, J., et al., Mechanisms for the Biomethylation of Metals and Metalloids. Federation Proceedings, Biological and Pharmacological Effects of Metal Con-taminants, Vol 37, No 1, pp 16-21, January 1978.

Ganser, A. L. and Krischner, D. A., The interaction of mercurials with myelin, Comparison of in vitro and in vivo effects. Neurotoxicology 6 (1): 63-78, 1985.

Henriksson, J., et al., Uptake of inorganic mercury in the olfactory bulbs via olfactory pathways in rats. Environ Research 77(2): 130-140, 1998.

Sjostrand, J., Fast and slow components of axoplasmic transport in the hypoglossal and vagus nerves of the rabbit. Cancer Research 18: 461-467, 1970.

Page 13

1-866-948-4638

How does this relate to people getting well or becoming more ill? The body is constantly balancing “degeneration versus regeneration”. This is a natural phenomena. We constantly get rid of aging cells, and replace them with new cells. Red blood cells live for 120 days, then are recycled out and replaced. White blood cells live only a week or two.

Degeneration—Regeneration.

Page 12


Autonomic Nervous System How does this happen? This decision is under the control of what is called the autonomic nervous system (ANS). The ANS decides when it is time to destroy and replace. It has two divisions. One for degeneration and one for regeneration. They are known as the sympathetic and para-sympathetic divisions. The sympathetic division is also known as the fight or flight division. When stimulated, these glands produce fight or die in trying hormones. To be specific, they are represented by the thyroid hormone, adrenalin, anterior pituitary and testosterone.

Counter to this action is the parasympathetic division of the ANS. These hormones include the parathyroid hormone, insulin, posterior pituitary and estrogen. Their specialty is in creating a calming and healing situation.

Should a dentist remove a positively charged dental filling first, the degeneration hormones are activated by the now-excess sodium in the synapse, creating an abnormal, hasty degeneration command.

Sequential Removal has the ability to balance the white blood cell count and increase the efficiency of your immune system.

(Right) Figure I

Demonstrates high white blood cell count dropping.

(Below) Figure II

Demonstrates low white blood cell count increasing.

Further examples of immune dysfunction are shown by sophisticated studies of T- lymphocytes (a specific type of white blood cell) performed at the University of Colorado during his post doctoral masters studies. He showed the destruction of T-cells by placement of dental materials within a few days. Methods of recovery were also revealed. (See figures III, IV and V on page 6)

Page 5

1-866-948-4638

White Blood Cell Response To Sequential Removal of Silver-Mercury Fillings

Figure III

Test results showing “normal” results for lymphocytes.

Figure IV

Results showing the destruction of T-lymphocytes within a few days.

Figure V

Results showing the beginning of recovery.

Page 6


Protons and Electrons

In touching a probe from an ammeter to a filling, the filling will generally register positive or negative. Sometimes it registers zero, which means that the filling has too much corrosion on it to allow electrical charges to escape. This does not mean that these fillings are safe. Actually, as a person eats, these corrosion products (several times more damaging than mercury vapor coming off the filling) are abraded off and mix with the food that is headed for the stomach, intestinal tract, and into the blood stream, with access to all parts of the body.

Here is my theory that explains the value of sequential removal.

When a filling registers “positive”, that means that protons are bombarding the ammeter’s probe, and, equal and opposite, electrons are rushing out the root end of the tooth. Directing our thoughts to the positive fillings, what is happening is that electrons are racing into the synapses of the brain. This influx of electrons creates an imbalance at the synapses, which causes the chemistry at the synapse to have to compensate, representing accommodation for survival.

Accommodation in this case involves bringing additional sodium ions into the synapse. Why? Because sodium can compensate for excess electrons and re-establish equilibrium in brain synaptic metabolism.

When the source of excess electrons is removed suddenly, as by the removal of a positively charged filling, compensating excess sodium no longer needed, but, at that moment, the synapse is over-saturated. Your nervous system has been compensating by leaning into the wind, so to speak, by providing excess sodium, and now it has to de-compensate because the electron challenge is no longer there.

Page 11

1-866-948-4638

Much of the action involves moving electrons (negatively charged) and protons (positively charged) within this space called the synaptic cleft. When everything is in balance, neurotransmitters stimulate the electrolytes to emit electrons that interact with protons and all the other electrolytes in that space resulting in the transfer of electrical energy from one nerve to the next.

Figure VII

A patient being tested with a meter designed to test electrical output from fillings to insure proper sequential removal.

In describing nerve impulse transmission, the most important element is the “synapse”, or space in between nerves. Nerves are not continuous, but are little snippets of nerve that convey electrical impulses along their fibers to a space that they have to jump to land on and to stimulate the next nerve fiber. A lot of complex bio-electro-chemical processes take place in that small space. There are chemicals called neurotransmitters that create chemicals at the end of one nerve. These chemicals jump into the space, and are directed to the other end of the chasm by calcium, magnesium, manganese, sodium, potassium and chloride all working in concert.

How it works...

Page 10


Figure VI

Demonstrates Cerebro Spinal Proteins of patients before and after dental revision.

Huggins has much more scientific data from thousands of patients that clearly demonstrates that certain dental materials (specifically mercury fillings and root canals) are not in the best interests of the health of unsuspecting, trusting patients.

Presence of abnormal proteins in spinal fluid in patients with Multiple Sclerosis that recovered to no abnormal proteins within 12 days utilizing the Protocol he discusses. (See figure VI)

Page 7

1-866-948-4638

In 1996 Dr. Huggins and a few friends funded a study to bring several extremely ill British Gulf War Syndrome Vets to

Colorado in the USA for treatment. This was an attempt to see if his Protocol would be effective against their conditions. His Protocol reversed the ravages of their conditions within a few days. Today all have recovered and are doing well.

Obviously, this data is upsetting to the dental profession due to the massive potential for litigation. Huggins proposes

that the dental profession and the public set aside legal issues and accusations and proceed toward the elimination of unnecessary diseases and symptoms.

Huggins cautions that the random removal of silver mercury fillings and root canal teeth can readily create new diseases. The Protocol he suggests involves using blood chemistries to guide health practitioner teams toward improving health and ridding the body of toxicity. It takes 3 days just to instruct the dentists in the methods of replacement of toxic substances with safer ones. Physicians need much more time to absorb the biochemical supportive and reconstructive methods for the injured immune system that must coordinate with the dental revisions.

“There are two ways to handle the situation”, to quote Huggins, “Fast, and Right.”

The Saga Continues...

A Word of Caution

Page 8


“Dr. Huggins’

Protocol

reversed their

conditions…”

Figure VII

Diagram of a synapse.

When we first discovered the tremendous advantage to removing fillings sequentially, we could see improvements in blood chemistry and symptoms very distinctly, but we had no clue as to why removing the negative fillings first produced improvements, and removing the positive fillings first produced a worsening of symptoms.

After 27 years of wondering, the answer suddenly appeared. I took a semester’s course in Forensic Toxicology at the University of Colorado in 2005, and while studying brain reactions to prescription drugs, the “Aha!” occurred. All the bits and pieces of information leading to answering the question “Why does sequential removal produce so much benefit?” became clear.

I quickly wrote up the 20 pages of brain electro-biochemistry and incorporated it with endocrinology. The result was pretty thorough, but pretty complex to read. I have condensed the salient points into the following paragraphs. This appears to be the most important of multiple aspects of the Protocol in terms of what is lost if it is omitted.

Sequential Removal

Page 9

1-866-948-4638

In 1996 Dr. Huggins and a few friends funded a study to bring several extremely ill British Gulf War Syndrome Vets to

Colorado in the USA for treatment. This was an attempt to see if his Protocol would be effective against their conditions. His Protocol reversed the ravages of their conditions within a few days. Today all have recovered and are doing well.

Obviously, this data is upsetting to the dental profession due to the massive potential for litigation. Huggins proposes

that the dental profession and the public set aside legal issues and accusations and proceed toward the elimination of unnecessary diseases and symptoms.

Huggins cautions that the random removal of silver mercury fillings and root canal teeth can readily create new diseases. The Protocol he suggests involves using blood chemistries to guide health practitioner teams toward improving health and ridding the body of toxicity. It takes 3 days just to instruct the dentists in the methods of replacement of toxic substances with safer ones. Physicians need much more time to absorb the biochemical supportive and reconstructive methods for the injured immune system that must coordinate with the dental revisions.

“There are two ways to handle the situation”, to quote Huggins, “Fast, and Right.”

The Saga Continues...

A Word of Caution

Page 8


“Dr. Huggins’

Protocol

reversed their

conditions…”

Figure VII

Diagram of a synapse.

When we first discovered the tremendous advantage to removing fillings sequentially, we could see improvements in blood chemistry and symptoms very distinctly, but we had no clue as to why removing the negative fillings first produced improvements, and removing the positive fillings first produced a worsening of symptoms.

After 27 years of wondering, the answer suddenly appeared. I took a semester’s course in Forensic Toxicology at the University of Colorado in 2005, and while studying brain reactions to prescription drugs, the “Aha!” occurred. All the bits and pieces of information leading to answering the question “Why does sequential removal produce so much benefit?” became clear.

I quickly wrote up the 20 pages of brain electro-biochemistry and incorporated it with endocrinology. The result was pretty thorough, but pretty complex to read. I have condensed the salient points into the following paragraphs. This appears to be the most important of multiple aspects of the Protocol in terms of what is lost if it is omitted.

Sequential Removal

Page 9

1-866-948-4638

Much of the action involves moving electrons (negatively charged) and protons (positively charged) within this space called the synaptic cleft. When everything is in balance, neurotransmitters stimulate the electrolytes to emit electrons that interact with protons and all the other electrolytes in that space resulting in the transfer of electrical energy from one nerve to the next.

Figure VII

A patient being tested with a meter designed to test electrical output from fillings to insure proper sequential removal.

In describing nerve impulse transmission, the most important element is the “synapse”, or space in between nerves. Nerves are not continuous, but are little snippets of nerve that convey electrical impulses along their fibers to a space that they have to jump to land on and to stimulate the next nerve fiber. A lot of complex bio-electro-chemical processes take place in that small space. There are chemicals called neurotransmitters that create chemicals at the end of one nerve. These chemicals jump into the space, and are directed to the other end of the chasm by calcium, magnesium, manganese, sodium, potassium and chloride all working in concert.

How it works...

Page 10


Figure VI

Demonstrates Cerebro Spinal Proteins of patients before and after dental revision.

Huggins has much more scientific data from thousands of patients that clearly demonstrates that certain dental materials (specifically mercury fillings and root canals) are not in the best interests of the health of unsuspecting, trusting patients.

Presence of abnormal proteins in spinal fluid in patients with Multiple Sclerosis that recovered to no abnormal proteins within 12 days utilizing the Protocol he discusses. (See figure VI)

Page 7

1-866-948-4638

Figure III

Test results showing “normal” results for lymphocytes.

Figure IV

Results showing the destruction of T-lymphocytes within a few days.

Figure V

Results showing the beginning of recovery.

Page 6


Protons and Electrons

In touching a probe from an ammeter to a filling, the filling will generally register positive or negative. Sometimes it registers zero, which means that the filling has too much corrosion on it to allow electrical charges to escape. This does not mean that these fillings are safe. Actually, as a person eats, these corrosion products (several times more damaging than mercury vapor coming off the filling) are abraded off and mix with the food that is headed for the stomach, intestinal tract, and into the blood stream, with access to all parts of the body.

Here is my theory that explains the value of sequential removal.

When a filling registers “positive”, that means that protons are bombarding the ammeter’s probe, and, equal and opposite, electrons are rushing out the root end of the tooth. Directing our thoughts to the positive fillings, what is happening is that electrons are racing into the synapses of the brain. This influx of electrons creates an imbalance at the synapses, which causes the chemistry at the synapse to have to compensate, representing accommodation for survival.

Accommodation in this case involves bringing additional sodium ions into the synapse. Why? Because sodium can compensate for excess electrons and re-establish equilibrium in brain synaptic metabolism.

When the source of excess electrons is removed suddenly, as by the removal of a positively charged filling, compensating excess sodium no longer needed, but, at that moment, the synapse is over-saturated. Your nervous system has been compensating by leaning into the wind, so to speak, by providing excess sodium, and now it has to de-compensate because the electron challenge is no longer there.

Page 11

1-866-948-4638

How does this relate to people getting well or becoming more ill? The body is constantly balancing “degeneration versus regeneration”. This is a natural phenomena. We constantly get rid of aging cells, and replace them with new cells. Red blood cells live for 120 days, then are recycled out and replaced. White blood cells live only a week or two.

Degeneration—Regeneration.

Page 12


Autonomic Nervous System How does this happen? This decision is under the control of what is called the autonomic nervous system (ANS). The ANS decides when it is time to destroy and replace. It has two divisions. One for degeneration and one for regeneration. They are known as the sympathetic and para-sympathetic divisions. The sympathetic division is also known as the fight or flight division. When stimulated, these glands produce fight or die in trying hormones. To be specific, they are represented by the thyroid hormone, adrenalin, anterior pituitary and testosterone.

Counter to this action is the parasympathetic division of the ANS. These hormones include the parathyroid hormone, insulin, posterior pituitary and estrogen. Their specialty is in creating a calming and healing situation.

Should a dentist remove a positively charged dental filling first, the degeneration hormones are activated by the now-excess sodium in the synapse, creating an abnormal, hasty degeneration command.

Sequential Removal has the ability to balance the white blood cell count and increase the efficiency of your immune system.

(Right) Figure I

Demonstrates high white blood cell count dropping.

(Below) Figure II

Demonstrates low white blood cell count increasing.

Further examples of immune dysfunction are shown by sophisticated studies of T- lymphocytes (a specific type of white blood cell) performed at the University of Colorado during his post doctoral masters studies. He showed the destruction of T-cells by placement of dental materials within a few days. Methods of recovery were also revealed. (See figures III, IV and V on page 6)

Page 5

1-866-948-4638

White Blood Cell Response To Sequential Removal of Silver-Mercury Fillings

As a result of treating thousands of patients, Dr. Huggins can demonstrate that dental materials control a person’s immune system. He showed examples of how high white blood cells can be reduced and low white blood cells increased by the same Protocol. (See figures I and II on page 5)

Immune Dysfunction

Ionic mercury effecting:

• Acute intracellular destruction (Friberg ‘86)

• Creation of “leaky membranes” (Friberg ‘86)

• Energy interference blocking Na-K pump (Aschner ‘90)

• Alters DNA (Canton and Costa ‘83)

• Creates neurotoxicity (Aschner ‘90)

Methyl Mercury effecting:

• Lipid soluble insidious poison (Lexmond ‘76)

• Endocrine disturbances (Friberg ‘86)

• Development of sensory neuropathy (Schionning ‘90)

• Plasmids convert ionic to methyl mercury (Konetzka ‘77)

• Muscle weakness (Rustam ‘75)

• Formation of haptens (Swartzendruber ‘88)

Page 4


“Dental

materials

control a

person’s

immune

system…”

These sympathetic hormones create a premature degeneration removal of tissues that are not really at the end of their life span - but there is no regeneration action to fill the vacancy. Thus, a new disease is created.

When fillings are removed sequentially, that is, with the negative fillings replaced first, the opposite scenarios takes place. As negative fillings are removed, a potassium efflux occurs at the synapse calling for an increase in parasympathetic hormones (parathyroid, insulin, posterior pituitary and estrogen). The result is to stimulate healing.

References Chew, C. L., et al., Long-term dissolution of mercury from a non-mercury re-leasing amalgam. Clin Rev Dent, 13 (3): 5-7, 1991.

Svare, C. W., et al., The effect of dental amalgams on mercury levels in expired air. J Dental Res 50: Sept 1981.

Wataha, J. C. and Craig R. G., The release of elements of dental casting alloys into cell culture medium. J Dent Research 70: 1014-1018, 1991.

Compeau, G. and Bartha, R., Methylation and demethylation of mercury under controlled redox, pH and salinity conditions. Applied & Envion Microbiol, Vol 38, No 6, 1203-1207, 1984. Wood, J., et al., Mechanisms for the Biomethylation of Metals and Metalloids. Federation Proceedings, Biological and Pharmacological Effects of Metal Con-taminants, Vol 37, No 1, pp 16-21, January 1978.

Ganser, A. L. and Krischner, D. A., The interaction of mercurials with myelin, Comparison of in vitro and in vivo effects. Neurotoxicology 6 (1): 63-78, 1985.

Henriksson, J., et al., Uptake of inorganic mercury in the olfactory bulbs via olfactory pathways in rats. Environ Research 77(2): 130-140, 1998.

Sjostrand, J., Fast and slow components of axoplasmic transport in the hypoglossal and vagus nerves of the rabbit. Cancer Research 18: 461-467, 1970.

Page 13

1-866-948-4638

Nylander, M, Friberg, L. and Lind, V., Mercury concentrations in the human brain and kidneys in relation to exposure from dental amalgam fillings. Swedish Dental J 11: 179-187, 1987.

Friberg, Lars, Nordberg, Gunnar F. and Vouk, Velimir B. (eds.), Handbook on the Toxicology of Metals, Vol. I. Elsesvier Science Publishing Co., New York, NY, 1986.

Aschner, M., et al., Mercury Neurotoxicity: Mechanisms of blood brain barrier transport. Neuroscience and Bio-behavioral Reviews, Vol. 14, 1990.

Canton, O. and Costa, M., Correlations of DNA strand breaks and their repair with cell survival, following acute exposure to mercury and X-rays. Molecular Pharmacology 24: 84-89, 1983.

Lexmond, T.M., et al., On the Methylation of Inorganic Mercury and the Decomposition of Organo-Mercury Compounds – A Review. Neth. J Agric. Aci. 24, 79-97, 1976.

Schionning, J. D., et al., Ultra-structural localization of mercury in rat dorsal root gan-glia after exposure to mercury vapor. Progress in Histo- and Cytochemistry, Vol 23, 1990.

Konetzka, W., Microbiology of metal transformation. Micro-organisms and Minerals, 317-342, 1977

Rustam, H., et al., Arch. Environ. Health, 30: 190-195, 1975.

Swartzendruber, D. E., Adverse Immunomodulatory effects of heavy metals in den-tal materials. Proceedings from the International Conference on Biocompatibility of Materials, 1988.

References Cont...

Page 14


Mercury from fillings can also create many common symptoms of “unknown” origin. Most commonly seen are symptoms of depression, anxiety, chronic fatigue, chronic headaches, digestive upsets and memory problems. These come from one or more of the three forms of mercury that can be created from the surface of “amalgam” fillings.

Mercury vapor effecting the:

• Optic nerve (Ganser ‘85)

• Nasal sinus (Henricksson ‘98)

• Lungs (Sjostrand ‘70)

• Blood Brain Barrier (Nylander ‘87)

Examples of results of exposure to each form include:

The three forms of mercury (called the 3 costumes of mercury) are:

1.) The vapor form - as it usually comes off from the filling (Chew, ‘91; Svare ‘81; Wataha ‘91)

2.) The ionic mercury form - also from the surface of the filling (Heintze ‘83)

3.) The methyl mercury form - formed by bacteria in the

mouth and in the intestinal tract. (Compeau ‘84; Wood ‘74)

Page 3

1-866-948-4638

Autoimmune diseases can be stopped and many times reversed by a Dr. Huggins’ Protocol involving neutralizing reactions to dental materials.

What is an autoimmune disease? One in which your body’s immune white blood cells destroy your own body’s tissue cells. Examples of autoimmune nervous diseases are Multiple sclerosis, Amyotrophic lateral sclerosis, Alzheimer’s, Lupus, Leukemia, Diabetes and seizures. Examples of hormonal autoimmune problems are diabetes, Hashimoto’s thyroiditis and infertility.

What creates the mistaken identity o f ce l ls as initiated from dental materials is the formation of a “Hapten”. A Hapten is a normal cell that acquires a hitch-hiker that alters the cells “self” i d e n t i f i c a t i o n code.

In this picture, mercury, as from a common dental silver-mercury filling (about 50% mercury), is shown attaching itself to a normal cell. The new cell - called the Hapten – is mistaken by the immune system as being a foreign cell

Good news!

“Hapten”

Page 2


Hal A. Huggins DDS, MS Dr. Hal A Huggins has been a cutting edge researcher in dental toxicity since 1973. Why cutting edge? Because he follows changes in immune reactivity relative to sensitivities to dental toxins—and reports them. He uses blood chemistry evaluations to determine what dental

materials and supplements are “naughty” and which are “nice”. This upsets a great financial institution that has had a low key white knight reputation for over 100 years. What are the consequences of his observations? Exposure of massive liability. Resulting in lie-ability. Greater liability than Enron. Greater than the tobacco fiasco. Who does it affect? Most everyone. Probably you.

He is presenting the observations of the last 37 of his 43 years of practice. These comments are connections he has seen between dental materials and incurable diseases. He has lectured professionally 1400 days in 46 of the U.S. states and 13 other countries. He has authored several books, written over 50 articles, and given over 1000 radio/ TV interviews.

He received a post-doc Master’s at the University of Colorado with emphasis on immunology/toxicology. He successfully pioneered treatments for autoimmune diseases due to dental toxins and has personally treated over 2500 toxic patients.

Which dental materials are implicated? Mercury, nickel, beryllium, copper, and toxins formed in dead or root canal teeth as well as in cavitations.

Page 15

1-866-948-4638

Many people have been told their health problems are all in their head because their symptoms or diseases have no medically known cause or treatment. Dr. Huggins has discovered that dental toxicity due to mercury in amalgam fillings is the cause of many of these unexplained diseases and symptoms. Other standard dental practices such as root canals have also been shown to contribute to many health issues that the medical community has no explanation for.

There is Hope!

HUGGINS Applied Healing 5082 List Dr Colorado Springs, CO 80919 Phone: 1-866-948-4638 DrHuggins.com E-mail: [email protected]

Creating Positive Health Alternatives

Visit our website!

Www.DrHuggins.com


Call us toll-free today! 1-866-948-4638

Balanced Chemistry

For Better Health

Are Dental Materials Toxic?

The Truth:

• Many unexplained symptoms are related to dental mercury and root canals.

• Many diseases of unknown origin are related to dental mercury and root canals. Mercury fillings cause negative blood chemistry shifts.

• Typical mercury damage sites have now been identified

• There are other dental toxins.

Help is available!

Hal A Huggins, DDS, MS 1-866-948-4638



Balanced Chemistry

For Better Health

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REVIEW ARTICLE

MEDICAL IMPLICATIONS OF DENTAL MERCURY: A REVIEW
Hal A. Huggins, DDS, MS1#
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ilver-mercury fillings—also called dental or mercury amalgams—ave been used in dentistry since 1832. In 1840, the dentalssociation of the day argued over whether to use mercury asfilling material because it was cheap, or to withdraw it

ecause it was toxic. The safety debate had already begun andould be called “Amalgam War I.” In the late 1920s, Dr Alfredtock, a biochemist and researcher, wrote close to 30 articlesescribing the toxicity of mercury and linking it to dentalmalgam fillings—this then became “Amalgam War II.” In973, some dentists and their patients began to question theafety of silver-mercury fillings when it became apparent thatome patients were reporting health improvements after re-oval of their mercury amalgam fillings. The primary pur-

ose of this review is to bring together much of the availableesearch and literature that focuses on health issues associatedith mercury in dental fillings, some of the basic science

nformation that is known about how the body processesercury, and to offer some observations from the practices of

entists removing dental mercury from their patients. Welso hope this review will draw attention to the potentialonnections between mercury released from dental fillingsnd autoimmune diseases. Many autoimmune diseases arelassified as diseases of unknown etiology; yet, the well-doc-mented toxic effects of mercury may explain some of theymptoms observed in autoimmune diseases.

NTRODUCTIONercury is generally accepted to be one of the most toxic of all

he metals in the periodic chart that are not radioactive. It comesn several forms—some are more destructive than others—andach has its own mechanism of toxicity. There are four possibleorms of mercury (called oxidation states), yet only three areommonly encountered. One is the vapor form (Hg0), another ishe ionic form, (Hg��), and the most toxic is the organic formCH3-Hg�) or methyl mercury.

Mercury vapor damage (Hg0) is almost entirely limited to theentral nervous system.1 This is the state in which mercury com-only escapes from silver-mercury fillings. Ionic mercury

Hg��) toxicity is often acute and produces local damage todjacent tissues—primarily directed toward organ systems. Theidney is often the primary target organ, although it can damageany other tissues.Methyl mercury is by far the most toxic of the mercury com-

ounds. This is due to its motility. It effortlessly travels to anyissue, recognizes no barriers, and can enter any cell without

Huggins Applied Healing, Colorado Springs, CO

Corresponding Author. Address:082 List Drive, Colorado Springs CO 80919
[email protected]
10 © 2007 by Elsevier Inc. Printed in the United States. All Rights ReserISSN 1550-8307/07/$32.00

ermission. Within a cell, it can destroy the various componentselectively or in totality by unleashing lysosomes, damagingNA, and by rupturing the cell membrane. Its effects upon theeripheral nervous system are demonstrated in diseases like sei-ures, tremors, multiple sclerosis (MS), and amyotrophic lateralclerosis, to name but a few. Mental and emotional diseases maylso result, as well as interferences in hormonal production andunction.

Dental fillings containing mercury are often called silver fill-ngs, primarily as a marketing tool that describes their color.

ercury is the primary component, making up close to 50% ofhe content; copper is next, comprising almost 30%. The re-aining 20% is divided among tin, silver, and zinc. There are

everal other names associated with these fillings. Dentists fre-uently refer to the silver-colored filling as an amalgam, whicheans mixed with mercury. Mercury appears to dissolve manyetals into a liquid phase that can be easily placed into multi-

haped containers, like the spaces dentists cut into teeth as theyemove cavities. Other names are also seen, most of which seemo be an effort to avoid using the word mercury. Given the un-erlying toxicity of mercury, our first consideration should beow much mercury is being released from dental fillings con-aining mercury.

ELEASE OF MERCURY FROM AMALGAMSercury is released from silver-mercury-amalgam-alloy fillings

y four basic methods:

. Mechanical Compression. Articles on the increased (up to15,000%) release of mercury from chewing gum have beenpublished.2 Eating and trauma are also contributing factorsto the release and subsequent storage of mercury in variousparts of the body.

. Chemical. When dissimilar metals are placed together insaliva (an electrolytelike solution), an electrochemical reac-tion can occur. With dental amalgams, the combination ofthe five different positively charged metals form at least 16different corrosive products on the surface of the filling.3

Other foods bring a variety of chemicals in contact with theelectrically charged metallic fillings, with a resultant multi-tude of other potentially corrosive products created, manyof which may be toxic. These products may be abraded offduring chewing or washed off by acidic foods like vinegarand oil dressing, soft drinks, fruits, and juices, and releasedalong with mercury vapor.

. Electrical. Chemical reactions among the various combi-nations of metals on the surface of amalgam produceelectrical current that can be measured. The negative poleof the electrical current produced by these metals canrelease mercury vapor. When measured, the amounts
given off can exceed OSHA’s limits for 40 hour per week
ved EXPLORE March/April 2007, Vol. 3, No. 2doi:10.1016/j.explore.2006.12.008

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exposures. Further confusion is created by the fact thatdifferent federal agencies have different safe-level stan-dards.4 And exposures from fillings occur 24 hours perday, not 40 hours per week, and therefore could exceedthe recommended safe limits.

. Temperature. Hot beverages, hot soups, and other hot foodsincrease the temperature of the surface of the fillings. Mer-cury follows the law of physics that states that chemicalreactions double for every 10°C increase in temperature.Coffee and tea are at the top of the list for increasing mercuryrelease due to temperature increases.

here Does Mercury Go After Being Released From theillings?ercury mixed with foods goes into the stomach, and from

here it can go into the intestinal tract and then on to the bloodtream. The mercury released directly into the mouth is ab-orbed into the cheeks or sublingually—both routes of absorp-ion end up in the blood stream. Most of the mercury thateaches the gastrointestinal tract is converted into methyl mer-ury by gastrointestinal tract bacteria5 that can be absorbedhrough most cell membranes.

Inhalation of mercury vapor directly from the oral cavity maynter the lungs, where it may be absorbed directly into the bloodtream. If mercury vapor remains in the blood stream for morehan a few seconds, it may be methylated—as methyl mercury itould pass through the blood brain barrier (BBB), after which itan be oxidized into the ionic form that damages brain tissue.lial cells in the brain have the highest affinity for absorption

nd storage of mercury of any cells in the body.Another method by which mercury is released from a filling

nto the body is by going from the filling, through the dentin,nto the pulp chamber of the tooth,6,7 and into the bloodtream, or by retrograde axonal transport, going directly into therain.8

Different forms of mercury in the body and different potentialodes of toxicity have been associated with the following:

interaction with macromolecules9

cross-linking of cell membranes10,11

rupturing the cell membrane9

lysing DNA11

mitochondrial interference12

interference with nerve impulse transmission13

alteration of the three-dimensional structure of a mole-cule14,15

interference with DNA replication11

interference with DNA repair15,16

alteration of cell membrane permeability17

altering the methylation/demethylation balance in the gut18

destruction of lysosomes within cells, releasing hydrolytic en-zymes that destroy cell contents and surrounding structures19

From the practical standpoint, interference with these mech-nisms may be responsible for potential functional aberrations,ncluding:

stimulation of the onset of autoimmune diseases20 a

eview of Dental Mercury

interference with endocrine function21

alteration of enzyme function22

displacement of other minerals, such as Ca, Mg, Zn, and Cr11

alteration in digestion and absorption23

formation of plasmids24

creation of birth defects23,25-29

ERCURY VAPORercury vapor (Hg0) released from fillings is the first form that

ttacks the body.2,30-32 It can travel through the nervous systemo the optic nerve and create optic neuritis,33 or it can travel intohe nasal sinus from which it has direct access into the temporalegion of the brain.34,35 In the brain, mercury vapor can produceigh neurological damage, but low systemic damage.36,37

On the way to the lungs, mercury vapor can travel via theagus nerve to the central nuclei in the brain stem,38 directly tohe lung,39 or to the gastrointestinal tract.38 From the lungs,ercury vapor can be transported into the blood stream, where

t may react with cells in the blood. Mercury vapor has beenocumented to suppress the activity of polymorphonuclear leu-ocytes.10 When mercury vapor enters erythrocytes, it may bexidized to form ionic mercury, which can immediately kill redlood cells.37 If the mercury vapor does not immediately kill theell, it may displace oxygen on hemoglobin,37 altering the three-imensional structure of the molecule.14 Mercury does not re-ease from hemoglobin once it attaches, which means that aomplete blood count may show a normal red cell count, hemo-lobin, and hematocrit; however, the displacement of oxygen byercury means the peripheral tissues may not be adequately

xygenated. The hematocrit can show as much as a 4% drop iness than a week by using procedures designed to rid the body of

ercury-contaminated hemoglobin, whereas the urine mercuryncreases several hundred percent, suggesting increased mercurylimination from the contaminated red blood cells. There is alsosimultaneous increase in oxyhemoglobin saturation of be-

ween 10% and 30%.Methylation of mercury vapor in the blood40 can also easily

nter the placenta. Developmental effects may include:

exposure at weeks 0 to 2 may result in a lack of implantation40

exposure at weeks three to four may result in adverse effectsinvolving the brain, heart, eyes, limbs, and ears40

exposure at weeks six to seven may result in adverse effectsinvolving the brain, heart, eyes, limbs, and ears, and contrib-ute to the formation of cleft palate40

exposure at weeks 9 to 12 may result in adverse effects involv-ing the eyes40

Not only can the placental barrier be penetrated by the meth-lation of mercury vapor, but the BBB and the central nervousystem can also be breached.41,42 Mercury vapor interacts withmino acid carriers in the BBB as well as with sulfhydryl groupsn the barrier itself.42

ONIC MERCURYonic mercury (Hg��) species can be formed on the surface of
malgam3,43 and be swallowed with or without food, ending up
111EXPLORE March/April 2007, Vol. 3, No. 2

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n the stomach. In the intestinal tract, there is absorptionhrough the adjacent linings36 that may leave a leaky membranen its wake.9 Ionic mercury enters cells by access through thealcium channels9 and interferes with cell membrane function,ncluding both the entrance of raw materials and the exit ofaste products. In the stomach, ionic mercury forms mercurichloride that may kill friendly bacteria, leading to indigestionnd malabsorption,44-46 or it may cause ulcers.9

Cells destroyed by ionic mercury spread their contentshroughout the surrounding tissues9 and are ultimately absorbednto the lymphatic drainage system; this may stress the liver oridney. When ionic mercury enters tissue cells, it can alter itsNA10 as well as destroy mitochondria.12 There is also a reduc-

ion in cellular energy if the mercury interferes with the sodium-otassium pump mechanism.42

In the nervous system, ionic mercury is again toxic.42 Evenhough it (unlike methyl mercury) cannot pass through theBB,47 methyl mercury can be converted into ionic mercurynce it has passed the BBB. It can then enter the cells via theodium and calcium channels48 and disrupt nerve impulse trans-ission by displacing ionic calcium from the cell membrane.9

xcretion of ionic mercury from the brain is especially slow ands measured in years.42

In the immune system, ionic mercury exposure lowers theiability of lymphocytes.20 Consequently, the differential countrom a complete blood count may give a false impression of theody’s defense ability. These compromised lymphocytes maytill appear in the cell counters or on histopathologic slides. It isronic that in scientific laboratories, injection of ionic mercury issed to increase the percentage of experimental animals withutoimmune disease.20 Could this effect be at work in humanss well?

ETHYL MERCURYercury vapor can be converted to methyl mercury (MeHg)

y the action of bacteria.5,49 Plasmids, a defense mechanismor bacteria to survive mercury toxicity, have the ability toonvert ionic mercury to methyl mercury.24 This is a life-aving procedure for the bacteria because methyl mercury cane eliminated by the bacterium through its cell wall beforehe ionic species can destroy the contents of the bacterium.o make matters worse, when bacteria form plasmids to dealith mercury toxicity, they may simultaneously become re-

istant to many antibiotics. Methylation of mercury is en-ouraged by antibiotics, while at the same time demethyl-tion is slowed.9

Methyl mercury can also be formed by the action of nega-ive electrical charge on the surface of saliva-coated amalgamllings as mercury vapor escapes from the fillings.5,50,51 A

ittle recognized method of methylation may be the action ofitamin B12. 52 Cysteine, a dietary supplement, also methyl-tes mercury.53 As methyl mercury cysteine, it is resorbed inhe large bowel and transported via the hepatic portal systemo the duodenum.

Methyl mercury is 45 times more lipid soluble than ionicercury (Hg��).49 This makes it particularly dangerous to nerve

ells, where the cell membranes have a higher lipid content (75% n

12 EXPLORE March/April 2007, Vol. 3, No. 2

s 40%) compared with cells from other tissue. Upon arrival inhe cell, methyl mercury is oxidized into ionic mercury andegins its destruction as outlined in the previous section. Plasmaembranes are the primary organ target for methyl mercury

MeHg).54 It attacks myelin protein,9 creates degeneration oferve cones,55 and causes the development of sensory neuropa-hy.56 Methyl mercury may prevent synaptic transactions13,57

hat may lead to numbness and tingling of the hands and feet,58

ome of the first signs associated with MS. Motor nuclei accu-ulation of methyl mercury may also cause constriction of vi-

ual fields, another sign of MS.59,60 Demethylation may de-rease, but does not eliminate, the toxicity of MeHg.56,61

Methyl mercury is not only dangerous because of its ability tonter cell membranes—another aspect of its toxicity is related tots interactions with enzyme bonds. This bonding induces ahange in conformation of the tertiary structure of proteins thatay result in a loss on enzymatic activity.18

Methyl mercury may also cause birth defects, as noted above,or mercury vapor. These may include alterations in the brain,eart, eyes, limbs, ears, cleft palate, cleft lip, and sex organs, asell as chromosomal damage, single strand breaks, and DNA–NA cross-links.10,62 There may be enough mercury in sperm at

he time of conception to create birth defects.

ENTAL RELEASE OF MERCURYirect exposure of mercury in the oral cavity is not the onlyethod of introduction of mercury into the brain and ner-

ous system through retrograde axonal transport backwardslong the trigeminal nerve to the brain. This fifth cranialerve enervates all of the teeth and has direct communicationith the brain. Mercury can be transported from fillings into

he pulp chamber.6,7,48 From the pulp chamber, it may beransported into the main branch of the nervous system viahe trigeminal nerve. As mercury travels along the trigeminalerve, it creates inflammation, resulting in adhesions on theanglion that may contribute to trigeminal neuralgia and mi-raine headaches.48

In the maxillary branch of the trigeminal nerve, mercury thatas traveled from the filling through the dentinal tubules intohe pulp chamber can move backward up the trigeminal nerve.he speed of retrograde axonal transport of mercury along theandibular branch of the trigeminal nerve has been measured at

0 mm per 24 hours into the trigeminal ganglion at the basenside the skull.63 This provides a pathway for microbial toxinss well as mercury into the cranial cavity.63 Retrograde axonalransport is not limited to mercury.7,35,63-69 This retrograde ax-nal transport system may move copper, antiseptics, bleach,ecay products, root canal toxins, and antibiotics.6,70

The hypoglossal nerve (XII) may also transport ionic andethyl mercury sublingually into the brain from the motorerve terminals via sodium and calcium channels.48 This mer-ury may be picked up sublingually because this is a primarybsorption area close to the fillings.

Mercury can also travel along the parallel valveless cranialenous system as well and might contribute to neurologicaliseases such as MS.21 Mercury in the central nervous systemoncentrates in the glial cells, which act as scavengers for the
ervous system.
Review of Dental Mercury

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Bacterial infection and inflammation at the apex of teeth mayccur around root canals or dead teeth. Specifically, Actinomycesacteria may move by retrograde axonal transport from deadeeth directly into the brain.70

LINICAL IMPLICATIONSoes Mercury Play a Role in Autoimmune Disease?he immune system has a surveillance team of white blood cells

hat constantly monitor the cells of the body for their permis-ion to be there. This monitoring is done through the majoristocompatibility complex (MHC), which identifies the cells ofhe body as “self.” All the body’s cells are coded with the same

HC, except red blood cells and sperm. If the MHC is al-ered—as with organ transplants—the surveillance team flags theell and another cell of the immune system will come along andestroy it. When normal cells (such as nerve cells) have as little assingle atom of mercury attached to a free sulfhydryl bond, theHC is distorted by one digit, and the immune system may

dentify this cell as “nonself.” This type of cell with a hitchhikers called a hapten, a normal cell with an MHC distortion.

White blood cells are particularly sensitive to the presence ofercury and other toxic materials, many of which are used inodern dentistry. In human studies, it is sometimes difficult to

ifferentiate which material might have caused damage in a liv-ng organism; however, we can isolate the biochemical reactionsn the laboratory.

Figure 1 demonstrates the trend for white blood cells to dropoward the stability point when the total protocol is followed.ven in extreme cases like leukemia, a positive responsive can beetermined within a few days.Even more difficult than reducing high white blood cells is

aising low white blood cell counts (Figure 2). The trend seems toe that upon initial exposure to mercury, white cells elevate in an

igure 1. White blood cell reponse to sequential removal of silver-ercury fillings.

ffort to eliminate the cause of hapten formation. Since mercury


annot be “killed” and is difficult to eliminate, it in turn may killhite blood cells, and after a period of time the white blood cellount may drop below the stability point. Figure 2 demonstrateshat there can still be a quick response toward the stability pointhen the primary irritant is removed sequentially.Viability tests can be run on separated lymphocytes in a lab-

ratory by using a standardized test focusing on lymphocyteegradation to separate living from dead cells. It is frequentlyssumed in a conventional complete blood count differentialount that all the white cells were alive at the time the slide wasxposed to air, dipped in alcohol, and stained. This may not berue, and if so, could give a false estimate of actual immuneapacity.

Figure 3 demonstrates what happens when isolated live lym-hocytes are viewed under a fluorescent microscopy by usingpecial dyes, such as propidium iodide, to allow visual separationf live from dead cells in live cultures. On the initial day of theest, 100% of the lymphocytes are alive—or viable—in this pa-ient. Viability counts use state-of-the-art method for separatingive from dead lymphocytes. A small amount of mercury (ap-roximating the amount that could theoretically be in the bloodf someone with four amalgams) was added. By day two, theontrol segment has dropped to 97% and the mercury test groupas dropped to 92%. By day four, the control group of cells stillaintains a viability of 97%, but the viability of the mercury-

xposed lymphocytes has dropped to 21%. This difference willot be shown on the conventional differential count, whichoes not look at viability.In the case of autoimmune diseases, the nervous system—part

f your “self”—is being destroyed by your own immune system,

igure 2. White blood cell response to sequential removal of silver-ercury fillings.

Figure 3. Lymphocyte viability when exposed to mercury.


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ee Figure 4. This onset may be associated with, but not limitedo, mercury toxicity. Toxins from anaerobes associated with rootanals may also be in part responsible for some of the same typef autoimmune reactions.

igure 4. Effects of mercury on cell membrane structure andunction.

Figure 5. Cerebro spinal proteins b


Figure 5 shows the results of [32P]8N3ATP photo labelingf eight cerebrospinal fluid samples taken pre– and 48-hourost– dental revision procedures. These four patients wereiagnosed with MS by magnetic resonance imaging prior toreatment. Cerebrospinal fluid solubilized proteins were thenubjected to SDS-polyacrylamide gel electrophoresis. Thenly proteins that are expected to be seen in healthy personsre albumins, and they were present pretreatment and post-reatment. There were multiple abnormal proteins present inhe pretreatment samples, but none in the posttreatment sam-les. All four patients improved symptomatically as the spinaluid cleared.71

Evaluation by two-dimensional gel did not identify the abnor-al proteins, and later it was postulated that they were fragments

f brain tissue found floating down from the brain into theerebrospinal fluid, and its source was eliminated by the removalf dental toxins.Figure 6 demonstrates the very low (12 mcg per 24-hour urine

ollection) amount of urinary porphyrin in an adult who neverad dental materials in his mouth. In other MS patients, theeduction of urinary porphyrins was related to clinical improve-ents.As a comparison in Figure 7, another MS patient shows 2,100

g of urinary porphyrin predental revision. These were dividedetween the 4, 5, 6, 7, and 8 carboxy porphyrins. This reduction

efore and after dental revision.


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rom 2,100 to 200 �g in 12 days gave the patient much morexygen (from the formation of hemoglobin from porphyrin) asell as more adenosine triphosphate (derived from heme; alsoerived from porphyrin breakdown) traveling through the cyto-hrome oxidase system. Even though root canals and amalgamllings are very different, they may result in the same type ofutoimmune destruction.

ENTAL IMPLICATIONSf having a root canal or putting in a mercury amalgam fillingay produce an autoimmune process in a person at risk, why

oes the process of reversal or taking out mercury amalgamsppear to be more complex? Factors to be considered include:1) Is a protective rubber dam used? (2) Are negative ion gener-tors used to remove mercury vapor from the dental atmo-phere? (3) Is dental replacement material serum tested for com-atibility and immune reactivity? (4) Is careful attention paid toalancing the blood chemistry as mercury amalgams are re-oved? (5) Are amalgams sequentially removed, first removing

egatively charged fillings, followed by positively charged fill-ngs?

It has been suggested that the removal of positively chargedllings may overstimulate the sympathetic division of theutonomic nervous system, whereas removal of the negativelyharged fillings first stimulates the parasympathetic nervousystem.

igure 6. Urinary porphyrin profile on a patient with no previousental treatment.

igure 7. Urinary porphyrin profile on a patient with MS pre vs post
ental treatment.

ONCLUSIONhe toxicity of mercury has been known for centuries and hasften been underestimated. We have yet to fully appreciatehe potential relationship between illness and the body’s ex-osure to mercury from a variety of sources, including dentalmalgams. It behooves us to be aware of these relationshipshen assessing the health of patients today, and further re-

earch, although complex and fraught with many confound-ng variables, is urgently needed.

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Phone: DrHuggins.com Visit our website! email@drhuggins ......2012/11/15 · Decomposition of Organo-Mercury Compounds – A Review. Neth. J Agric. Aci. 24, 79-97, 1976. Schionning,