Phosphoryl-Group Transfer

• Phosphoryl-group-transfer potential - the ability of a compound to transfer its phosphoryl group

• Energy-rich or high-energy compounds have group transfer potentials equal to or greater than that of ATP

• Low-energy compounds have group transfer potentials less than that of ATP

Transfer of the phosphoryl group from PEP to ADP

• Phosphoenolpyruvate (PEP) (a glycolytic intermediate) has a high P-group transfer potential

• PEP can donate a P to ADP to form ATP

Structures of PC and PA