Hashemite University
Faculty of Medicine
1st year syllabus – 1st semester
COURSE INFORMATION
Course ID
0102109
Course title
General physics for Medicine Students
Course time
10:00 - 11:00, 12:00 –1:00
Credit hours
3 Credit Hours (3 Lectures/week)
Prerequisite(s)
-
Instructor’s
Name
Feras M. Al-Dweri
Office
location/phone
Physics Building 110
Course Duration
16 weeks
Email
Office hours
11:00 – 12:00
TEXT BOOK INFORMATION
Text book title
Physics
Auther(s)
J. Kane
Publisher/Year
1988
Edition
3rd
REFERENCES
1.Physics for health sciences, Carl R. Nave and Brenda C. Nave,
W. B. Saunders
Company 1985, third edition.
2.Physics for Scientists and Engineers with Modern Physics by
Raymond A.
Serway and John W. Jewett, sixth edition, Thomson Brooks/Cole,
2004.
3.Fundamental of Physics by David Halliday, Robert Resnick and
Jearl Walker, fifth edition, John Wiley and Sons, 1995.
COURSE OBJECTIVES
This general physics course is prepared to provide students with
knowledge needed for their majors in medical studies as well as
various geological and environmental studies. Topics covered will
include mechanics, heat, fluids, electricity, waves, and
radioactivity. This course is essential to prepare students for
better understanding of the basic concepts and principles of
physics.
The course is, also, intended to train the student on new
mathematical techniques whenever possible, and to provide her/him
with sufficient practice in solving problems. For best achievement
of the above objectives, students are not only
urged to solve the problems recommended by the instructor, but
also solve as much as they can of the other problems as well as
problems from the other two reference books.
EVALUATION POLICY
Type
Weight
First exam
25%
Second exam
25%
Final exam
50%
Other activities
COURSE CONTENTS
Part one :Mechanics (6 weeks)
Ch.1 Motion in a straight line: Sections: 1.1,
1.2,1.3,1.4,1.5
Ch.2 Motion in two dimensions: Sections: 2.1, 2.2, 2.3
Ch.3 Newton’s laws of motion: Sec.: 3.1, 3.3, 3.4, 3.5, 3.6
Ch.4 Statics: Section: 4.1
Ch.5 Circular motion: Sections: 5.1, 5.2, 5.3, 5.4
Ch.6 Work and energy: Sections: 6.1,6.2, 6.3
*** FIRST EXAM ***
Part two: Fluids (2 weeks)
Ch.13 Fluid Mechanics: Sections: 13.1, 13.2, 13.3, 13.4, 13.5,
13.6
Part three: Electricity (5 week)
Ch.16 Electric force, field and potential: Sections: 16.1, 16.2,
16.4, 16.8
Ch.17 Electric current: Sections: 17.1, 17.2, 17.3, 17.5
Ch. 18 The Description of wave motion: 21.1, 21.2, 21.3
*** SECOND EXAM ***
Part four: Waves (2 weeks)
Ch.22 Sound: Sections: 22.1, 22.2, 22.3
Ch.23 Wave properties of light: Sections: 23.1, 23.2, 23.3,
23.4, 23.5
Part five: Radioactivity (1 week)
Ch.30 Nuclear physics: Sections: 30.1, 30.2
The Hashemite University
Faculty of Science
Department of Chemistry
Course Information
Course Title
General Chemistry
Course Number
0103101
Course Credits
3 hours (3 Lectures/week)
Course time
Section 1: Sun. Tue. and Thu. 9:00-10:00
Section 3: Sun. Tue. and Thu. 12:00-1:00
Prerequisite(s)
---.
Lecture room
Section 1: Chem. 229
Section 3: Chem. 229
Course Duration
16 weeks
Instructor
Dr. Ismail Fasfous
Chem. 212
Sun. 8:00-9:00, Mon. 8:00-9:00, Tue. 11-12, Thu. 1-2
[email protected]
Office Location
Office Hours
E-mail
Text Book
Title
Chemistry
Author(s)
Raymond Change
Publisher
McGraw Hill
Year
2010
Edition
10th edition
References(s)
Any library book related to general chemistry
Evaluation Policy
Assessment Type
Expected Date
Weight
1st Exam
Third week of march
25%
2nd Exam
Last week of April
25%
Final Exam
To be announced
50%
Attendance: University regulations require students to attend
all lectures. Attendance will be taken in class. If you miss an
exam due to illness, a medical report should be submitted to the
instructor no later than two days after the exam. In this case your
grade will be obtained from your performance in the other exams. If
you miss an exam without a medical excuse a grade of zero will be
given for that exam.
Note: No makeup exams for both first and second tests!
Course Objectives
The course aims at studying the basic principles of chemistry,
which will construct the base for higher chemistry courses and will
supple the basic knowledge needed for this science.
Teaching and Learning Methods
Lectures on board, as well as, using overhead projector and LCD
projector (data show). In addition, there will be assigned hours
during the semester for helping in the course by Teaching
Assistants.
Course Contents
Chapter
Topics
Tentative No. of
1
Chemistry: The study Change
4
3
Mass Relationship in Chemical Reactions
6
4
Reactions in Aqueous Solutions
7
5
Gases
5
7
Quantum Theory and the Electronic Structure of Atoms
7
8
Periodic Relationships Among the Elements
4
9
Chemical Bonding I: Basic Concepts
5
10
Covalent Bonding II: Molecular Geometry and
Hybridization of Atomic Orbitals
4
The Hashemite University
Faculty of Science
Department of Biology
Course Title
General Biology 101
Course Number
0104101
Course Credits
3 hours (3 Lectures /week)
Course Time
Course Duration
16 weeks
Prerequisite(s)
Instructor
Course coordinator
Dr. Salim AlMaloul
Office Location
Office Phone
Office Hours
E- mail
Course Web Site:
Text Book
Title
Biology
Author(s)
N. Campbell and J. Reece
Publisher
Benjamin Cummings
Year
2005
Edition
7th
References(s)
* Copies of the text book are in the library.
* Older editions may be used
Note:
Evaluation Policy
Weight
Expected Date
Assessment Type
25%
Week 6
First Exam
25%
Week 12
Second Exam
50%
Week 16
Final Exam
Teaching and Learning Methods
1. Lectures (Transparencies of chapter figures)
2. Class room discussions of questions at the end of
chapters.
Course Objectives
This course introduces the major biological concepts such as
order and organization, structure and functions and provides the
students with the abilities to relate life with the various
functions carried out by the cell.
Course Contents
Week
Topics
Chapter in
Text
1
2
3
4
5
6-7
7-8
9
10-11
12-13
14
15
16
Carbon and the molecular diversity of life
The structure and function of macromolecules
Metabolism
The cell
Membrane structure and function Cellular respiration
Photosynthesis
Mitosis and meiosis
Mendelian genetics
Chromosomal basis of inheritance Molecular basis of inheritance
Gene expression
Review
4
5
8
6
7
9
10
12, 13
14
15
16
17
Course Name: Practical General Biology (1) Course Number:
0104103
Course credits: 1 hour (1 Three hours Lap/week)
Course Description:
This course focuses on the following: the microscope, the cell,
physical and chemical properties of the cell, cell division,
metabolism and organismal diversity (including prokaryotes,
protista, fungi and animals).
Course objectives:
To acquire the basic concepts in microscopy and its
applications, the cell and its different organelles, the main
chemical and physical properties of the living organisms, the basic
aspects of metabolism, modes of cell division, principles of
genetics and to be familiar with animal biodiversity.
Text book:
Dr. Ramsis Lutfy et al. 1993 (2nd edition) Laboratory Manual of
General Biology. The University of Jordan Press, Amman.
Supplementary Text:
1. Madar, S. S (1993). Laboratory Manual of Biology. 4th
edition. Wm. C. Brown
Pub. USA.
2. Morgan, J. D. and Carter, E. B. (1999). Investigating
Biology. 3rd edition. Benjamin-Cummings Co. USA.
3. Campbell and Reece. (2001). Biology. 6th edition.
Benjamin-Cummings.
Course Schedule:
Topic
Week
General Instructions And Basic Tools And Instruments Used In
Biology Lab.
1
The Light Microscope
2
The Cell
3
Chemical Aspects Of Living Organisms I
4
Chemical Aspects Of Living Organisms II
5
Chemical Aspects Of Living Organisms III
6
Midterm Exam
7
Physical Properties Of The Cell
8
Metabolism
9
Cell Division
10
Kingdom Monera And Protozoa
11
Fungi, Porifera, Cnidaria And Platyhelminthes
12
Nematoda, Annelida And Arthropoda
13
Mollusca, Echinodermata And Chordata
14
Mollusca, Echinodermata And Chordata
15
Final Exam
16
Grade Distribution:
Reports& Quizzes
20%
Midterm Exam
30%
Final Exam
50%
Total
100%
General instructions:
1. Attendance of laboratory sessions is a must. No lab
make-ups.
2. Contact your instructor immediately if you know in advance
you will miss a laboratory session. Do not wait until the next day
of your absence or to the next week
3. It may be possible for you to attend a lab session in another
lab section, if you missed your regular lab session, but only in
the same week and under the permission of your instructor.
4. There will be no make-ups on the lab quizzes. If you attended
another lab section with a scheduled quiz, you must take the quiz
given by the other instructor.
5. Missing a lab practical exam or quizzes is an automatic zero
for the exam or quiz.
6. Lab drawings are due at the end of the laboratory period.
7. Every student must wear a white lab coat; no student is
allowed to enter the lab without a lab coat.
8. Avoid loose-fitting items of clothing; jackets and ordinary
coats will be placed on benches designated for this purpose.
9. Food and drinks are not allowed in the lab.
10. Keep your workplace free from unnecessary materials
(clothing, books, handbags, etc) by placing them in the drawer of
your bench.
11. shoulder-length hair should be tied back in a ponytail to
avoid injury from Bunsen burner.
12. Report spills and accidents immediately to your lab
instructor.
13. Do not return unused chemicals to the stock bottles.
14. Wash all the glassware and instruments you used in the lab.
at the end of each experiment.
15. Always keep your bench clean, remove all garbage before
leaving the lab.
16. Wash your hands with water and soap provided at the sink
before leaving the lab.
Hashemite University
Faculty of Medicine
1st year syllabus – Second Semester
Course Title: General Physiology. Course Code: 1502102
Course credits: 2 hours.
Calendar description:
16 Weeks/Semester 2/ First year.
Course coordinator: Prof. Faik Hussain Mohammed
Evaluation and distribution of Marks:
- First in-course exam (MCQ) = 30 Marks.
- Second in-course exam (MCQ) = 30 Marks.
- Final exam at the end of the semester (MCQ) = 40 Marks.
General Objective:
1. To introduce and familiarize students with basic definitions
and principles related to physiology as a study of the living body
at molecular, cellular as well as the level of intact organism.
2. To introduce the concept of internal environment and
homeostasis and to present some examples of homeostatic mechanisms
of the major functional systems and various control systems that
are utilized by different organs to regulate various physiological
functions.
3. To cover the physiological implications related to
circulating body fluids and homodynamic.
4. To describe the principles and mechanisms of membrane
transport.
5. To describe the physiological implications related to
circulating body fluids.
6. To describe the electrical and ionic events that underlines
the excitation of nerves, muscles as well as the mechanism
underlying skeletal
muscle contraction.
7. To describe synaptic transmission and electrical properties
of synaptic potential.
8. To cover the general organization and functional aspects of
the autonomic nervous system.
9. To describe the general principles and mechanisms of
synaptic
transmission.
Recommended text book:
• Text book of Medical Physiology, by Guyton and Hall, latest
edition.
• Human Physiology From Cell to System, by Lauralee Sherwood,
latest edition.
Lecture Topics
Lectures
1&2
- General outline of physiology, Definition and fields of
physiology, with
emphases on human physiology.
- Cells as the living units of the body.
- The origin of nutrients and removal of end products of
metabolism in unicellular versus multicellular organisms, the
external and internal environments.
- The role of circulating body fluids, the continuous fluid
exchange between the blood (transporting media) and interstitial
fluid, and its regulation.
Lectures
3&4
- The external and internal environment, the extracellular fluid
as the internal
environment.
- The concepts of homeostasis.
- The concepts of feedback mechanisms (negative and positive
feedback).
Lectures
5&6
- Total body water (TBW).
- The effect of age, and sex.
- Body fluid compartments.
- The composition of the extracellular fluid (ECF).
- The composition of the intracellular fluid (ICF).
Lectures
7&8
- Measurement of body fluid compartments - the
indicator-dilution principle.
- Fluid exchange between ICF and ECF.
Lectures
9&10
- The principle of osmosis and osmotic pressure.
- Mole, osmole, osmolality and osmolarity, the relation between
osmotic pressure and osmolarity.
- Isotonic, hypotonic, and hypertonic fluids.
- Isosmotic, hyperosmotic, and hypo-osmotic fluids.
Lectures
11&12
- Volume and osmolality of ECF and ICF in abnormal states.
- The microcirculation and the lymphatic system
- Edema.
Lectures
13&14
FIRST EXAM
- Transport of substances through the cell membrane.
Passive transport:
a. simple diffusion (criteria, factors determine diffusion). b.
facilitated diffusion.
- Active transport:
a. primary active.
b. secondary active: Co- and Counter-transport.
Lectures
15&16
- Phagocytosis and pinocytosis.
- Excitable membranes. Resting membrane potential (RMP), origin,
and determinants.
- Electrochemical equilibrium (Nerst equation).
- Goldman-Hodgkin-Katz equation.
Lectures
17&18
- Action potential (AP) initiation and propagation.
- Special types of AP, slow response and the pacemaker
concept
Lectures
19&20
- Cardiac AP (fast response AP).
- Latent and ectopic pacemakers.
- All or non vs. graded AP.
Lectures
21&22
- Synapses: types, transmission of AP, neurotransmitters.
- Excitatory post synaptic potential (EPsP).
- Inhibitory post synaptic potential (IPsP).
Lectures
23&24
SECOND EXAM
- Signal transduction.
- Extracellular regulators: nervous, endocrine, paracrine, and
autocrine.
- Receptors: membrane and intracellular.
- Ions channels.
- cAMP and cGMP.
Lectures
25&26
- Autonomic nervous system I
- Sympathetic and Parasympathetic.
- Autonomic nervous system II
- Neurotransmitters, types, and location (preganglionic and
postganglionic).
- Receptors, types and location.
- Adrenal Medulla.
Lectures
27&28
- Skeletal muscle.
- Level of organization in muscle.
- Neuromuscular Junction and Neuromuscular transmission.
- Excitation contraction coupling and molecular basis of
skeletal muscle contraction
Lectures
29&30
- Smooth and cardiac muscle contraction. Comparison of three
types of
muscle; skeletal, smooth and cardiac
Week 16 FINAL EXAM
Course Title: General Anatomy
Course Number: 1501101
Credit Hours: 3 hours (2 Lectures + 1 (Three Hours) Lab / Week)
Semester: Second Semester, Feb 2011
Duration: 16 Weeks
Instructors: Dr. Adib Aughsteen & Dr. Saad AlSabti
Course Description:
1. The course begins with understanding; the definition and
significance of anatomy and its subdivisions; the terms of position
and movements; and the regional terms applied in the study of human
gross anatomy.
2. The course introduces the basic structures encountered while
dissecting a cadaver (skin, fascia, skeletal muscles, bones,
joints, blood & lymphatic vessels, nervous system
organization).
3. The course the main structures and functions of different
body systems; Skeletal, Muscular & Joints, CVS, Respiratory,
GIT, Urinary, Male and Female Genital, and Nervous systems.
4. The course also covers the general embryology which describe
the development of embryo, foetal membrane, placenta and the causes
of congenital malformations.
Course Objectives:
1. The student should be familiar with the terms used in the
study of anatomy.
2. The student should be familiar with basic knowledge
concerning the main structures faced while dissecting a human
cadaver.
3. The student should be oriented with the structures and their
arrangement in each
system of human body which help him in building good basic
anatomical knowledge for subsequent modules.
4. The students should be familiar with basic knowledge of
general human embryology including the process fertilization,
zygote formation, implantation, embryonic period, fetal membranes
and placenta formation, and the main causes of congenital
malformations.
Recommended Textbooks:
1. Principle of Human Anatomy, G.J. Tortora & M.T. Nielsen,
11th Edition, 2009 or
Latest
2. Clinical Anatomy for Medical Students, R.S. Snell, any
Edition.
3. Netter Atlas of Anatomy, Latest Edition.
4. Before We Are Born, K.L. Moore & T.V.N. Persaud, 7th
Edition, 2008 or Latest.
Recommended Web Sites:
1. http://www.getbodysmart.com/
2.
http://www.med-ed.virginia.edu/courses/anat/learningAids.cfm
3. http://www.anatomyatlases.org/
4. http://msjensen.education.umn.edu/wenanatomy/
Exams:
Midterm Exam 30%
Practical Exam 30%
Final Exam 40%
Lectures Outline, 1st Year, 2nd Semester
Lecture
Topic
General Objectives
1
Introduction
to Anatomy
1. Definition of anatomy, subdivisions of anatomy,
anatomical position.
2. Body planes, Terms of position (Directional Terms), Regional
Terms
2
Introduction
to Anatomy
1. Body Cavity, Subdivisions & Contents
2. Levels of Organization
3
Introduction
to Skeletal
System
1. Outline the gross type of bones
2. Describe the external features of long bone
3. Outline surface markings of bones
4. Outline the histological types of bones
5. Outline the parts of body skeleton
4
Axial
Skeleton
Skull
1. Outline the bones of axial skeleton
2. Describe the general features of skull
3. Introduce the bones of skull; sutures, fontanels &
their significances
4. Describe briefly the cranial cavity and base of skull
5. Outline important foramens of skull
5
Axial
Skeleton Skull & Mandible
1. Describe the features of mandible
2. Describe the general features of vertebral column
3. Describe the structure and significance of intervertebral
discs.
4. Outline the typical parts of the vertebra
5. Describe briefly the main features of regional vertebrae,
sacrum & coccyx
6
Upper Limb
5. Describe briefly the sternum and ribs
1. Outline the bones of upper limb
2. Describe the main features of clavicle, scapula &
humerus
7
Appendicular
Skeleton
Upper Limb
1. Describe the features of ulna & radius
2. Outline the general features and name of carpal bones
3. Describe the features of metacarpal and phalanges
8
Appendicular
Skeleton
Lower Limb
1. Outline the bones of lower limb
2. Describe the main features of bones of hip; ilium, ischium
& pubis
3. Describe the main features of femur & patella
9
Appendicular
Skeleton
Lower Limb
1. Describe the features of tibia & Fibula
2. Outline bones of foot and arches of foot
3. Outline the gross parts, blood & nerve supply of skeletal
muscle
4. Outline the types of skeletal muscles
5. Outline the nomenclature of skeletal muscles
6. Outline the type of actions of skeletal muscles
10
Muscles of
Scalp, Face, Eye & Ear
1. Outline the muscles of scalp & face
2. Outline the Muscles of mastication
3. Outline the muscles of middle ear
4. Outline the extra-ocular muscles of eye
11
Muscles of
the Neck
4. Outline the main muscles of neck
2. Outline the muscles of pharynx & larynx
3. Outline the prevertebral muscles of neck
12
Muscles of
Upper Limb
1. Outline the main muscles of pectoral, shoulder and
scapular region (origin, insertion, nerve supply &
action)
2. Outline the muscles of arm, forearm & hand
13
Muscles of
Thoracic, Abdominal & pelvic walls
1. Outline the muscles of thoracic wall
2. Describe the diaphragm
3. Outline the muscles of anterior abdominal wall
4. Describe briefly the perineum
14
Muscles of
Lower limb
1. Outline the muscles of gluteal region & back of thigh
2. Outline the muscles of anterior & lateral compartments of
thigh
1. Outline the muscles of leg
2. Describe the popliteal fossa
3. Outline the muscles of foot
15
Body Joints
1. Outline the type of body joints
2. Outline the structure and types of synovial joints
3. Describe the shoulder, elbow, radio-ulnar and wrist
joints
4. Name all joints of upper limb
16
Body Joints
Outline the joints of lower limb (hip, Knee, ankle &
joints of foot
17
Mid Term Examination (60 MCQ Written Exam)
18
Circulatory
1. Outline the parts of circulastory system
System
2. Briefly describe the pericardium
3. Briefly describe the heart (location, chambers, valves, blood
supply)
1. Outline the great vessels of heart
19
Circulatory
System
1. Outline the branches of aorta
2. Outline the vessels of head & neck
3. Outline the blood vessels of upper & lower limbs
20
Respiratory
System
1. Outline the parts of respiratory system
2. Outline the structure of nasal cavity, nasopharynx, paranasal
sinuses
3. Outline the larynx (cartilages, muscles & vocal
folds)
4. Describe briefly the trachea, principle bronchi &
bronchial
5. Describe briefly the pleural sac
6. Describe briefly the lungs
21
Digestive
System
1. Outline the parts of digestive system
2. Describe briefly the mouth, esophagus
3. Outline the location, parts, openings, borders and peritoneal
folds
4. Introduce parts & functions of small bowel
22
Digestive
System
1. Outline the parts, location and function of large
intestine
2. Outline the associated digestive glands and their functions
(salivary glands, pancreas, liver & gall bladder
23
Urinary
System
1. Outline the parts of urinary system
2. Briefly describe the location, gross structure & blood
vessels of kidney
3. Briefly outline the ureter, Urinary bladder & male
&
female urethra
24
Male Genital
Systems
Outline the parts & functions of male genital system
25
Female
Genital
System
Outline the parts & functions of female genital system
26
Nervous
System
1. Outline the anatomical and functional parts of NS
2. Outline the parts of CNS (brain & spinal cord)
3. Outline the meninges, parts & ventricles of brain
4. Outline the lobes & functions o0f cerebral hemisphere
5. Outline the sulci, gyri & important functional areas
27
Nervous
System
1. Outline the type of nerve fibers of white mater of
cerebrum
2. Name the deep nuclei of cerebrum
3. Outline the other parts of brain (thalamus, hypothalamus,
midbrain, pons, cerebellum & medulla oblongata
28
General
Embryology
1. Embryologic Terms (Sperm, Oocyte, Embryo, Zygot,
implantation, Conception, Blastomeres, Morula, Blastocyst,
conceptus Primordium, Fetus, Abortion, Labour)
2. Outline the process of spermatogenesis
3. Outline the process of Oogenesis
4. Describe the Process of Fertilization
29
General
Embryology
1. Describe Zygot Cleavage, Formation of Blastocyst &
implantation (1st Week of development)
2. Describe the 2nd Week of Development
30
General
Embryology
1. Describe briefly the 3rd Week of Development of
embryo from 4th – 8th Weeks
2. Describe Fetal Membranes & Placenta
31
General
Embryology
1. Describe Causes of Congenital Anomalies
2. Outline Procedures & techniques used to Assess
Foetal status
32
Final Exam
Outline of Anatomy Labs
Week
Topics
1
Skeletal System/ Upper Limb
2
Skeletal System/ Lower Limb
3
Skeletal System/Skull & Mandible
4
Skeletal System/Thoracic Cage & Vertebral Column
5
Muscular System/ Muscles of Scalp, Face, Mastication,
6
Muscular System/ Muscles of Thoracic Wall & diaphragm
Muscles of Upper Limb
7
Muscular System/ Muscles of Anterior abdominal Wall
Muscles of Lower Limb
8
Cardio-Vascular System (Heart & Blood Vessels)
9
Respiratory System
10
Digestive System
11
Uro-Genital System
12
Nervous System
13
Revision
14
Practical Exam
Notes:
1. Lab coat is a must.
2. Bring your personal notes and atlas.
3.Lab session is Three Hours duration
4. Attend your assigned lab sessions in time.
5. Attending other lab session is absolutely forbidden unless
approved by the instructor.
Course Information
Course Title
Organic Chemistry For Nonmajors
Course code
0103236
Course Credits
3 hours
Course Time
Su, Tu, Th and
Mo; We
Course Duration
16 weeks
Prerequisite(s)
103101
Instructors
Dr. Kayed Abu-Safieh, (Office & phone: 207; 4499)
[email protected]
Dr. Badr Salameh, (Office & phone: 201; 4126)
[email protected]
Dr. Abdullah Saleh (Office & phone: 214; 4739)
[email protected]
Office Location
Chemistry Department
Office Hours
Course Web Site:
Text Book
Title
Organic Chemistry
Authors
Harold Hart, Leslie Craine, and Daivid Hart.
Publisher
Houghton Mifflin Company,
Boston U.S.A.
Year
2007
Edition
12th edition.
References(s)
1) Organic Chemistry, 8th ed., By Solomons.(2004)
2) Organic Chemistry, J. McMurry (2004)
Evaluation Policy
Assessment Type
Weight
First Exam
25%
Second Exam
25%
Final Exam
50%
Course Objectives
The main objective of the course is to teach students the basic
principles of organic chemistry. The first part of the course will
cover the fundamental aspects of structural organic chemistry to
familiarize the students the main families of organic chemistry
functions as well as the 3D structure of organic molecules. The
basics of reactivity will also
covered using the mechanisms. The course will be frequently
illustrated will examples linked
to other scientific disciplines, in particular to the field of
life sciences.
Teaching and Learning Methods
The following teaching techniques will be used: Solved examples
to be done traditionally on the board Overhead transparencies may
be used for complex molecules
Course Contents
Week
Topics
Ch. in Text
1,2
Bonding and Isomerism
CHAPTER 1
3
Alkanes and Cycloalkanes
CHAPTER 2
4
Alkenes and Alkynes
CHAPTER 3
5
Aromatic compounds
CHAPTER 4
6,7
Stereoisemerism
CHAPTER 5
8
Organic Halogen Compounds
CHAPTER 6
9,10
Alcohols, Phenols, and Thiolos
CHAPTER 7
11
Ethers and Epoxies
CHAPTER 8
12
Aldhydes and Ketones
CHAPTER 9
13&14
Carboxylic acids
CHAPTER 10
15
Amines
CHAPTER 11
16
Final Exam
COURSE TITLE: HISTOLOGY & Cell Biology
COURSE NUMBER: 1501102
COURSE CREDITS:
3 hours (2 Lectures + 1 (3 Hours) Histology Lab/Week)
SEMESTER: Second Semester DURATION: 16 Weeks COORDINATOR: Dr.
Aiman Al Sharei
Course Information:
Histology is one of the basic medical courses. Histology is the
science for researching normal microscopic structures, ultra
structures and their related function. Through patterns of class
lecture, the students will be made to master the basic knowledge
and theory of histology and the human histological structures.
Students also should train themselves to use the microscope
correctly and cultivate their abilities in analysis, description of
histological structures. In addition, the attention should be paid
to cultivate the students’ abilities to use the syllabus, textbook,
laboratory guide and to study by themselves, for elevating the
students’ foreign language level. This course demands the student
to master main English technical terms which are also included in
the examination. Through studying this course the students will be
given the basis for studying other basic courses and medical
clinical course. In the following paragraphs, brief objectives of
subjects taught in the syllabus will be listed as follow.
GENERAL OBJECTIVES:
1- To describe the methods of tissue preparation for microscopy
examination.
2- To list and understand the different types of light and
electron microscopes.
3- To describe different histological techniques used in the
study of tissues.
4- To recognize the structure types & function of the four
basic types of tissues
(epithelium, connective tissue, muscular and nervous
tissues).
5- To describe the basic structure and function of the cell.
6- To explore basic molecular aspects of certain cellular
components (membrane, cytoskeleton, matrix).
RECCOMMENDED TEXTBOOK:
1) Basic Histology, text & atlas; L C Junqueria & J
Carneiro, 12th edition or latest, McGraw-Hill Medical Publishing
Division.
Exams:
Important notes:
- Attendance at lectures is required (and will be taken).
- Lab coat is a must.
- Attend your assigned lab session.
Histology Lectures
Weeks
Specific Objectives
WK 1: Introduction
1) To understand methods of tissue preparation for
histological
examination
2) To be familiar with the types & applications of light and
electron microscopes
3) To know briefly about histological techniques used for tissue
& cell
study (e.g. Histochemistry)
WK 2: Epithelium 1
1) To describe the general features & characteristics
epithelium
2) To understand the basic structure & functions of Basal
Lamina or
Basement Membrane
3) To understand the structure & function of intercellular
junctions
(tight, adherent, gap & desmosome)
WK 3: Epithelium 2
1) To describe cell surface specialization (Villi, Stereocilia,
Cilia &
Flagella)
2) To classify the epithelium into covering & lining,
glandular, simple and stratified
3) To be familiar with types, location, functions of covering
& lining
Epithelia
WK 4: Epithelium 3
1) To understand the structural & functional types of
exocrine glands
2) To describe basic histological structure of endocrine
glands
3) To understand the different types of epithelial cells (Ion-
transporting, pinocytotic, mucous, serous, steroid-secreting,
diffuse neuroendocrine)
WK 5:
Connective Tissue
1
1) To understand the basic features & characteristics of
connective
tissue
2) To recognize the different cells of connective tissue,
proper
(fibroblast, macrophage, plasma, mast)
3) To describe the main types of collagen fibers, and the
features of collagen type I
WK 6:
Connective Tissue
II
1) To describe the structure, features of reticular &
elastic fibers
2) To explore the basic structures of ground substance
3) To describe the structure, location and functions of
connective tissue proper (loose, dense)
4) To describe connective tissue with special features (elastic
tissue, reticular tissue, mucous tissue)
WK 7:
Connective Tissue
III
1) To describe the types & features of adipose tissue
2) To explore the structure, location & growth of hyaline
cartilage
3) To describe the structure & features of elastic
fibrocartilage
WK 8:
Connective Tissue
IV
1) To describe the basic features of bone, bone cells &
matrix
2) To describe the structure of periosteum & endosteum
3) To know the histological types of bones
4) To differentiate between primary and secondary bone
tissue
WK 9:
Connective Tissue
V
1) To understand bone histogenesis (intramembranous,
endochondral)
2) To describe bones classification, growth & remodeling
3) To understand metabolic role of bone tissue
4) To understand the structure of joints
WK 10:
Midterm Exam
WK 11:
Nerve Tissue & Nervous System 1
1) To describe the organization of nervous system
2) To describe the structure of nerve tissue (neural cell body,
dendrites, axon)
3) To understand the types & functions of glial cells
WK 12:
Nerve Tissue & Nervous System II
1) To describe the layers & structure of meninges (dura,
arachnoid, pia)
2) To describe the structure & function of blood brain
barrier
3) To describe the structure & function of choroid plexus
&
cerebrospinal fluid
4) To describe the components of peripheral nervous system, the
structure of myelinated, unmyelinated nerve fibers and nerves
WK 13:
Nerve Tissue & Nervous System III
1) To describe the structure of sensory & autonomic
ganglion
2) To understand autonomic nervous system (sympathetic &
parasympathetic)
3) To describe the features degeneration, regeneration of nerve
tissue &
the role of neural stem cells.
WK 14: Muscle Tissue
1) To describe skeletal muscle tissue; organization, structure
& nerve
supply
2) To describe the features of cardiac muscle tissue
3) To describe the features of smooth muscle
WK 15:
Revision
WK 16:
Final Exams
Histology Labs
Weeks
Specific Objectives
WK 1 & 2
Microscopy
WK 3 & 4
Epithelium 1
WK 5 & 6
Epithelium 2
Connective tissue proper
WK 7 & 8
Connective tissue special features
Cartilages
WK 9 & 10
Bone
WK 11 & 12
Muscular tissue
WK 13 & 14
Nervous tissue
WK 15
Revision
WK 16
Exam
COURSE TITLE: HISTOLOGY & Cell Biology
COURSE NUMBER: 1501102
CREDIT HOURS: 3 hours (2 Lectures + 1 (3hours) Histology
Lab/Week) Semester: Second Semester
DURATION: 16 Weeks
Instructor: Dr. Nabil Amer (M.D, Ph.D)
Text Book: Biochemistry by Mary Campbell & Shawn Farrell
Sixth Ed. 2009, Thomson Books/Cole ISBN 0-534-39499-X
Objectives of the Course:
This course is designed as an introductory course to
Biochemistry for Medical students to make them familiar with the
major aspects of the cell at the molecular level.
This course consists of topics flow from cell basics to
structure and functions of certain macromolecules such as amino
acids and proteins. This course also introduce various laboratory
techniques especially protein purification techniques. Knowledge of
organic chemistry is a prerequisite for this course.
Topic
No. Of Lect.
- Introduction
1
- Biochemistry and organization of cells
1
- Water, the solvent for biochemical reactions
2
- Amino acids and peptides:-
- structure, function and properties
- some small peptides of physiological importance
- structural levels of proteins: 1ry,2ry,3ry and quaternary
-relation of protein structure and function, muscle
contraction
3
- Protein Purification & characterization techniques
2
- Lipids & Membranes:-
- Types of lipids & their chemical nature
- The nature of biological membrane
- Some functions of membranes
2
- Structure of monosaccharides & their reactions
2
- Some important oligosaccharides
- Structure & functions of polysaccarides
- Glycoproteins
2
Hashemite University
Faculty of Medicine
1st year - summer semester syllabus
Course title: General Biochemistry (1502101)
Course credits:
3 Credit Hours
Time: Summer Semester, First Year
Text Book: Biochemistry by Mary Campbell & Shawn Farrell
Sixth Ed. 2009, Thomson Books/Cole ISBN 0-534-39499-X
Instructor: Dr. Nabil Amer (M.D, Ph.D)
Objectives of the Course:
Biochemistry - the study of the life at the molecular level.
This course aims at introducing first year medical students to the
basic chemical & biological foundations of biochemistry
starting with enzymes and leading to the energy production and
metabolism of carbohydrates, lipids and proteins. Throughout the
course, aspects of human biochemistry are presented in the context
of their function. This is followed by descriptions of how these
functions are disrupted in the presence of disease at the
biochemical level. Metabolism can be well understood only by
knowing the basic principles of Biochemistry. Disorders of
metabolism and the resultant diseases occupy
the major portion of clinical medicine. Biochemical
investigations and the results are of immense diagnostic,
therapeutic and prognostic significance. Knowledge of organic
chemistry is a prerequisite for biochemistry.
Methods of Teaching:
This course includes 48 lectures & 3 exams. The lectures are
given using overhead projector with good quality transparences. A
summary of the lecture & objectives of each chapter is given at
the beginning of the lecture. The students are allowed to ask
questions before, during and at the end of the lecture. In each
lecture, a quick summary of the previous lecture is given at the
start of the lecture. The students are allowed to record the
lecture & to take handouts from the lecturer.
Methods of Evaluation
Two in-course exams represent 60 % & one final exam worth 40
% of the final grade. All exams are of MCQs and using online
methodology. The questions cover all the objectives of all topics.
Questions can be direct, informational, analytical, and may test
student’s ability to make clinical scientific judgments.
Course Syllabus
Topics
No. of
lect.
Enzymes: general properties, classification, enzyme kinetics,
inhibition,
regulation, mechanisms, clinical enzymology
8
Energy Metabolism: Principles of cellular bioenergetics, TCA
cycle,
oxidative phosphorylation.
>>>>>>>>>>>>>>>>FIRST
EXAM
<<<<<<<<<<<<<<<
6
30 %
Carbohydrate Metabolism : glycolysis, gluconeogenesis, pentose
phosphate
pathway & glycogen metabolism
8
Lipid Metabolism: Fatty acid synthesis & oxidation.
Ketone
bodies.Cholesterol & lipoprotein metabolism.
>>>>>>>>>>>>>>>>SECOND
EXAM
<<<<<<<<<<<<<<<
6
30 %
Amino Acid Metabolism: Synthesis & catabolism.
6
Integration of Metabolism: Connections between metabolic
pathways
5
Biochemistry and Nutrition : Vitamins & minerals.
Obesity
Revision
7
2
>>>>>>>>>>>>>>>>FINAL
EXAM <<<<<<<<<<<<<<<
40 %
Total Number of lectures = 48
Total Number of exams = 3
Marks: First Exam = 30
Second Exam = 30
Final Exam = 40
Course name: Introduction to Community Medicine
Course code: 1505101
Credit hours: 3 hours
Instructor
Dr Hasan Hawamdeh. Ph.D Office Number: 053903333 ext:
[email protected]
Office hours: Sunday and Tuesday 13.30-14.30
Description:
This course is an introductory course intended to introduce
undergraduate students in a variety of disciplines to the basic
tents of public health. The course will provide an introduction to
primary health care, mother and child health (MCH) and health care
system,
Objectives
Upon completion of this course, the student will be able to:
1. Understand the concept of community medicine
2. Construct and comment on a population pyramid and compare
between different population pyramids.
3. Describe the consequences of different pattern of population
growth
4. Define the main components influencing population growth,
ferity rates, mortality rates and migration
5. Examine the determinants of health
6. Recognize the various types of health service
7. Describe the structure of primary health care and how it is
implemented
8. Understand the difference between primary care and specialty
care
9. Understand how the health services should be organized to
meet the actual needs of the entire population and not merely the
selected groups
Grading:
As Bs Cs Ds.
Grading methods:
There will be 3 exams comprised of multiple choice, quizzes,
short essays and short answers.
First…………….30% (the 4th week)
Second ………...30% (the 7th week) Final …………. .40% (the 8th
week)
References and Course materials
Essentials of Public Health. Bernard J. Turnock, MD, MPH.
ISBN-13:9780763745257
Handouts provided in class or on course website
Attendance policy:
Students are responsible for satisfying all academic objectives.
Acceptable reasons for absence from class include illness, serious
family emergencies, severe weather conditions and participation in
official University activities.
Make up exams:
If you are absent for a reason approved above and have given
prior notification to the instructor when possible, you will be
given adequate time to make up any exam missed. All other missed
will receive grade of zero.
Classroom etiquette:
Turn off all cell phones upon entering the classroom. Please
also make every attempt to arrive to class on time. We hope to
engage the class in discussions and encourage you to ask questions
of the instructor, but please keep side conversations to a minimum.
Cell phones are not allowed during exams. If any student is seen
using or looking at a cell phone, he/she will receive a grade of
zero on the exam. If you are expecting an emergency call, please
notify the instructor before class and we will hold your phone for
you.
Course schedule
Lecture
Objectives
1+2
Introduction
1- describe in details the various
components of the course
2- explain the instructions followed during the course
3- define teaching methods and tools applied during the
course
3 +4
The concept of community
medicine
1- understand the meaning of
community medicine
2- identify the aims and objectives of community medicine
3- describe the community medicine
development
4- identify the components of community medicine
5- understand the future of community
medicine
6- identify the rule of community doctor
5+6
Population science
(demography)
1- understand the meaning of
population science demography)
2- identify the elements of demography
7+8
Population pyramids
1- explain the concept of the population
pyramid
2- explain how to construct population pyramid
3- identify the types of pyramids
4- interpret population pyramid
9
Population dynamics
1- fertility indicators
1- understand how to calculate the
crude birth rate
2- understand how to calculate the fertility rate
3- understand how to calculate the specific fertility rate
10
2- mortality rate indicators
1- understand how to calculate the
crude death rate
2- understand how to calculate the cause specific death rate
3- understand how to calculate the sex
specific death rate
4- understand how to calculate the age specific death rate
11
3- migration
1- explain the meaning of migration
2- identify the types of migration
12
The population of Jordan
1- define the population size
2- describe the characteristics of
Jordanian population pyramid
3- identify the population problems of
Jordan
4- identify the benefits of controlling the population
explosion
5- explain the methods to manage the population of Jordan
13+14
Primary health care
1- understand the concept of primary
health care
2- identify the principle of primary care
3- clarify the strategies for the delivery of primary health
care
4- identify the components of primary health care
15+16
Health education
1- identify health education
2- identify health education program
3- state the purpose of planning for health education
program
4- recognize the steps for planning a health education
program
First exam
17+18
Maternal and Child Health
(MCH)
Under five health services
1- identify the different services
available in the MCH center for children under five years
old
2- explain the objectives of preventive, curative and follow up
services for infants and preschool children
3- identify the uses of growth charts used in the center
4- interpret different shapes of growth curves and their
indications
5- identify high risk babies and children
6- define the health indicators used to monitor the services for
infant and preschool children
7- assess the development of a child
19-24
Practical session
Visit to comprehensive health center
25+26
Maternal and Child Health
(MCH)
A- Under five health
B- Rreproductive health
1- discuss the importance of good
antenatal care
2- Identify the main maternal health problems
3- Observe the clinical and obstetrical examination
4- Identify high risk pregnancy
27-32
Women and reproductive
health (practical session)
Visit to comprehensive health center
2nd exam
33+34
Expanded program on
vaccination (EPI)
1- discuss the important of vaccination
2- identify the schedule of EPI
3- Identify the different contraindication to vaccinations
4- Identify the components of cold chain
35-36
Expanded program on
vaccination (EPI) (practical session)
Visit to comprehensive health center
37+38
Family planning program
1- discuss the importance of family
planning program
2- identify the basic program components
3- recognize the essential activities for birth control
services
4- identify factors favoring use of
contraceptive method
5- assess the importance of counseling in the context of family
planning program
39+40
Family planning program
(practical session)
Visit to comprehensive health center
FINAL EXAM
Hashemite University
Faculty of Medicine
2nd year – 1st semester syllabus
Course title: Genetics and Molecular Biology
Course code: 1503201
Credits: 2 Credit Hours
Time: First Semester, Second Year
Text Book: Biochemistry by Mary Campbell & Shawn Farrell
Sixth Ed. 2009, Thomson Books/Cole ISBN 0-534-39499-X Instructor:
Dr. Nabil Amer (M.D, Ph.D)
Objectives of the course :
This course starts with the purine and pyrimidine biosynthesis
and catabolism. A quick review of the chemotherapeutic agents that
interfere with purine and pyrimidine nucleotide metabolism. An
introduction to the structure of nucleic acids. The replication of
DNA is discussed in prokaryotes and eukaryotes. Transcription in
prokaryotes and eukaryotes and gen regulation is discussed in
details. Translation of the genetic message and protein synthesis
and posttranslational modification of proteins and protein
degradation is also covered in this course beside the site of
action of different antibiotics on protein synthesis. The final
part of the course focuses on biotechnology techniques in nucleic
acids including cloning, genetic engineering, DNA fingerprinting
and DNA libraries and polymerase chain reaction.
Throughout this course a biochemical connections highlight
special topics of particular interest to students. Topics
frequently have clinical implications, such as cancer, AIDS, Lupus,
and nutrition. These topics help students make the connection
between molecular genetics and the real world.
Methods of Teaching:
This course includes 32 lectures & 3 exams. The lectures are
given using overhead projector with good quality transparences. A
summary of the lecture & objectives of each chapter is given at
the beginning of the lecture. The students are allowed to ask
questions before, during and at the end of the lecture. In each
lecture, a quick summary of the previous lecture is given at the
start of the lecture. The students are allowed to record the
lecture & to take handouts from the lecturer.
Methods of Evaluation
Two in-course exams represent 60 % & one final exam worth 40
% of the final grade. All exams are of MCQs and using online
methodology. The questions cover all the objectives of all topics.
Questions can be direct, informational, analytical, and may test
student’s ability to make clinical scientific judgments.
Course Syllabus
Topic
1. Introduction
No. Of Lect.
1
2. Purines & pyrimidines metabolism
4
3. Nucleic acids
- levels of structure, supercoiling
- structure of DNA and DNA de-naturation
- principal kinds of RNA & their structures
4
>>>>>>>>>>>> FIRST EXAM
<<<<<<<<<<<<<<<<<<<<<<<<<<<<
30 %
4. Nucleic Acids:
- DNA Replication & repair
4
- Transcription, post-transcriptional modification
4
- Genetic regulation of transcription
- Ribozymes
- Process of translation, genetic code, post-translation
modification
3
5. Protein synthesis:
- Translation of the genetic message.
- Protein degradation
5
>>>>>>>>>>>>>>>
SECOND EXAM
<<<<<<<<<<<<<<<<<<<<<<<<
30 %
6. Nucleic acid Biotechnology techniques:
6
- DNA sequencing
- Recombinant DNA and cloning, DNA libraries,
biotechnology techniques
- The polymerase chain reaction
- Gene mapping and genetic engineering, gene
therapy
7. Revision
1
>>>>>>>>>>>>>>>>>FINAL
EXAM
<<<<<<<<<<<<<<<<<<<<<<<<
40 %
Total Number of lectures = 32
Total Number of exams = 3
Marks: First Exam = 30
Second Exam = 30
Final Exam = 40
Course title: General Pathology
Course Number: 1503202
Calendar description: 16 weeks/ 1st Semester/ 2nd Year
Credit Hours: 2 {1.5 Hours Theory + 0.5 Hour Practical)
Teaching Approaches:
Two Lectures / week One (3 Hours) Laboratory every other
week
Course Coordinator: Dr. Mohammed Kamel Alwiswasi, MB, ChB;
(Baghdad) 1970; Ph.D. (Newcastle upon Tyne, UK) 1978; F.R.C.Path
(Histopathology) London.1980.
Recommended Book:
Robbins Basic Pathology, 8th Edition, © 2007By Kumar, Abbas,
Fausto, and (&) Mitchell, SAUNDERS.
Course Description:
Pathology is the branch of medicine that deals with the
scientific study of the causes, mechanisms, structural &
functional changes of human diseases. Therefore, it is one of the
main foundations of medicine & it serves to bridge basic
medical disciplines with clinical sciences.
Pathology as a whole is usually divided into two parts:
A. General Pathology
B. Systemic Pathology.
In this course, it is only the first part, the general pathology
that is going to be covered. General pathology deals with disease
processes in general, & the study of the basic molecular,
cellular, & tissue (histopathological) reactions to different
injurious agents.
۞ Objectives of the General Pathology course are to:
1- Understand basic tissue reactions to different types of
injuries.
2- Know the etiology (cause) of major diseases.
3- Know the pathogenesis (how) of the diseases.
4- Describe the morphological effects (gross & microscopic
changes) produced by the diseases.
5- Describe the effects of the disease on the function of
organs.
6- Know the outcome & the possible complications of the
disease.
Topics cover in this course includes 26 Lectures and 8 Labs
:
1- Cell injury, cell death, & adaptations - Chapter 1, 30pp
in Six (6) Lectures,
2- Inflammation (Chapter 2, 28pp) & Repair - Chapter 3, 20pp
in Eight (8) Lectures.
3- Hemodynamic Disorders - Chapter 4, 26pp in Four (4)
Lectures,
4- Neoplasia - Chapter 6, 50pp in Eight (8) Lectures.
* Systemic pathology examines the particular responses of
specialized organs, & will be
covered in 87 Lectures and Labs in Nine (9) Modules in the
integrated system courses.
* Lectures are going to be in the form of interactive &
discussion type in which lecturer will address the specific
objectives of each topic & try to clarify & demonstrate
important concepts. Flow chart, tables & photographs used will
be from the recommended textbook & from selective atlases.
* Lecture notes for each topic is available (in a total of 177
pages)
* Practical classes:
The objective is to be familiar with the morphological patterns
of disease through looking at photographs, gross &
histopathological sections & link those with pathogenic
mechanisms & specific disease. Tutors will attend these
laboratory sessions to assist the students & help in answering
their questions about microscopic sections.
* Examinations: There will be 2 (mid & second) written
in-course exams, 25 (Twenty five) marks for each (a total of 50),
10 marks will be allocated for the practical exam & 40 (forty
marks) for the final written exam, a total of 100.
☼ Written & practical exams will be in the MCQ format.
Topics covered in this course includes 26 lectures :
1-Cell injury, cell death & adaptations.
Including introduction to pathology , cellular responses to
stress & noxious stimuli; cellular adaptation to stress,
causes, morphology,
mechanisms and examples of cell injury and necrosis; apoptosis,
intracellular
accumulations, pathological calcification and cellular aging.
(six lectures ) .
1st General Pathology Lecture
Cell injury , adaptations
- Discuss & enumerate cellular adaptations and describe each
type .Hypertrophy, hyperplasia, atrophy & metaplasia , and
mention their clinical significance .
2nd.Generalpathology lecture.
Reversible Cell injury.
Enumerate the types of injurious agents that cause cell
injury
.And mention their exact role in cell injury.
Define reversible & irreversible cell injury, mention their
gross, microscopic & ultrastructural features, as well as their
clinical significance .
Define hydropic degeneration & Fatty changes , and describe
their gross & microscopic features.
3rd General pathology lectures
Irreversible cell injury
Necrosis & apoptosis
Define necrosis & apoptosis .
Mention & differentiate between each type regarding their
gross, microscopic & ultrastructural features .
Describe the nuclear changes in necrosis .
Discuss the causes, pathogenesis,and features of apoptosis .
Give examples for apoptosis .
Discuss the subcellular injury of mitochondria , cytoplasmic
organelles, cell membrane & DNA.
4th. General pathology
lecture
Patterns of necrosis
Enumerate the patterns of necrosis , including coagulative ,
liquifactive, fibrinoid, fat necrosis, caseating &
gangrenous . Discuss each type and mention their causes and their
clinical significances.
5th & 6th. General pathology lecture
Discuss & describe intracellulara accumulations,
&aging.
2- Acute and chronic inflammation .Healing & Tissue
repair
Eight Lectures .
1st. Lecture( Inflammation )
Define inflammation, mention the causes, the types acute ,
chronic & subacute .The cardinal signs & nomenclature .
Discuss the vascular & cellular responses in acute inflammation
.
Discuss the causes of increased vascular permeability.
Discuss the mode of leukocytic cell margination , sticking
& rolling, immigration ,chemotaxis & phagocytosis .
Describe the gross & microscopic features of acute
inflammation.
2nd & 3rd
Lecture ( Inflammation)
Mention the role of chemical mediators in inflammation.
Enumerate the types of chemical mediator , their source
&
mode of action .
Enumerate the patterns of inflammation, & describe each type
, mention their gross & microscopic features & clinical
significance .
Define abscess, ulcer, pus ,exudates & transudate .
4th . Lecture ( Inflammation )
Discuss the outcome of acute inflammation .
Enumerate inflammatory cells both in acute & chronic
inflammation, describe each cell, & mention their role in
inflammatory processes.
5th. Lecture (Inflammation)
Define chronic inflammation , discuss its forms ,
pathogenesis & outcome .
Define granulomatous inflammation.
Enumerate the causes of granulomatous reactions. Describe the
microscopic features of granulomas.
6th. Lecture (Inflammation)
Discuss the local effects of inflammation, both beneficial
& harmful effects.
Discuss the systemic effects of inflammation & it’s
pathogenesis.
th& th
.Lecture ( Healing & repair)
Define tissue healing & repair.
Discuss the types of somatic cells ,and stem cells. Discuss the
role of growth factors in healing process. Discuss the role of
extracellular matrix in healing process. Describe the primary union
& secondary union in healing of skin wounds.
Enumerate causes of delay of healing process.
Define keloid,proud flesh scar.
3- Hemodynamic Disorders:
Including edema , hyperemia & congestion.
Haemorrhage , hemostasis & thrombosis, embolism ,and
infarction
(In four lectures) .
1st. Lecture
Edema, congestion &
hyperemia
Define edema, enumerate the causes, and discuss it’s
pathophysiology .
Describe the morphological features of localized &
generalized edema .
Define hyperemia , discuss it’s causes & it’s clinical
significance . Define congestion, discuss the causes ,
pathophysiology & it’s clinical, gross & microscopic
features.
Describe liver congestion (nut-meg liver), & pulmonary
congestion
2nd. Lecture
Hemorrhage & Hematomas
Discuss hemorrhage , external & internal hemorrhages,
mention the
nomenclatures of external bleeding like epistaxis, hematuria
…etc. What is a hematoma ? describe the gross & microscopic
features . Define petichae , purpura,& ecchymosis.
Discuss the clinical significance of hemorrhage.
3rd. Lecture
Hemostasis & Thrombosis
Define thrombosis. Enumerate it’s causes. What is Virchow’s
triad?
Describe endocardial , arterial , venous & postmortem
thrombi, discuss their causes , gross & microscopic features
& clinical significance .
Discuss the fate of thrombus .
Discuss the causes , pathophysiology, gross & microscopic
features and the clinical significance of DIC .
4th. Lecture
Embolism & Infarction .
Define embolism .Enumerate it’s types: thromboembolism, fat, air
,
amniotic fluid , bone marrow & air embolism.
Discuss the pathogenesis , it’s gross, microscopic &
clinical
features .
Define infarction .Describe the gross & histological
features. Causes of white & red infarctions .
Discuss the factors that influence the formation of an infarct
.
4- Neoplasia :
Including nomenclature , characteristics of benign and malignant
tumors,
epidemiology , the molecular basis of cancer ( carcinogenesis ),
etiology of cancer & carcinogenic agents, the host defense
mechanisms , and the clinical
aspects of neoplasia ( effects, grading, staging & diagnosis
of cancer). ( lectures ).
1st. & 2nd
Lectures Neoplasia
Define neoplasm, discuss, benign & malignant tumors ,
nomenclature of tumors.
Discuss the differences between benign & malignant cells ,
regarding microscopic features & biological behavior. Define
hamartoma , teratoma , mixed tumors
Dysplasia ,mild, moderate & sever dysplasias carcinoma in
situ .
rd th
3 & 4 Lectures
Biological features of
neoplasia
Discuss the biological features of malignant tumors , the
cell
morphology , anaplasia , modes of spread & metastases,
Discuss the epidemiology of cancer. Causes of cancer , chemical
carcinogens ,& biological carcinogens .Occupational &
hereditary cancers. Preneoplastic lesions .
5th.& 6th. Lectures
Carcinogenesis
Discuss carcinogenesis , define oncogene , discuss the
multistep
theory of neoplasia , the pathogenesis of carcinogenesis .The
chromosomal changes in cancer.
th& th . Lecture
Paraneoplastic
syndrome , grading , staging of cancer.&
lab. Diagnosis.
Discuss the effects of cancer on host.
Define the paraneoplastic syndromes & ectopic hormones .
Define the grading of cancer.
Define staging of cancer & mention the TNM,AJM, staging
systems used.
Discuss the laboratory diagnosis of cancers .
Practical Classes :
The objective is to be familiar with morphological patterns
of
diseases through looking at photographs of gross &
histopathological sections & those with pathogenic mechanisms
& specific disease.
Eight practical sessions were held in this module:
1st&2nd practical pathology Labs
Cell injury :
The students are informed about tissue processing & a
visit
to the pathology lab. to have an idea about used instruments
& be informed about how histological sections & cytology
specimens were prepared . A review of gross morphology ,&
histological sections of reversible & irreversible cell
injuries were done including hydropic degeneration, fatty
changes, necrosis & apoptosis.
Types of necrosis and cellular accumulations .
3rd&4th practical pathology
Labs.
Inflammation :
The students were informed to identify the gross &
microscopic features of acute & chronic inflammation, to
identify the types of inflammatory cells The patterns of
inflammation .To identify abscess, ulcer & granulomas.
The gross & microscopic features of healing & repair are
reviewed , including granulation tissue & fibrous scars &
keloid.
5th&6thPractical pathology Labs.
Hemodynamic Disorders :
The students are informed to identify the gross &
microscopic appearances of edema , congestion , hemorrhages
, hematomas ,thrombosis , embolism & infarction .
th&8 thPractical pathology Labs.
Neoplasia :
Differentiate between benign & malignant tumors. Describe
a
benign & a malignant tumor . Discuss grading & staging
of cancer
Summary of the Teaching Activities in the Module :
Subject
Number of Lectures
Practical Labs (3hrs/lab).
Cell Injury
6
2
Inflammation
2
Hemodynamic disorders
4
2
Neoplasia
2
Total
26
Course Title: General Microbiology
Course Code: 1503203
Credit Hours:
Course Instructor:
3 Credit Hours ( 2 Lectures + 1 (3hour) Lab /week)
Dr. Sameer Naji, MB, BCh, PhD
Description:
This course is an introductory course intended to introduce
undergraduate medical students to a variety of subjects in medical
microbiology. The course will provide an
introduction to Bacteriology, Mycology, Parasitology, and Vi
rology, Through 40 Lectures and 8 Labs .
Objectives:
Upon completion of this course, the student will be able to:
1. Understand the concept of medical microbiology
2. Understand the bacterial cell structure, growth, nutrition
and genetics
3. Describe the various methods of sterilization and
disinfection
4. Understand the various types of antimicrobial
chemotherapy
5. Recognize the various types of culture media and culture
methods
6. Differentiate between Gram positive and Gram negative
bacteria as well as mycobacteria, rickettsia, chlamydia, mycoplasma
and spirochaetes
7. Differentiate between the various types of fungi
8. Understand the difference between protozoa and helminths
9. Understand the viral structure, replication, and genetics
10. Understand the pathogenesis and immunity to viral
infections
11. Describe the various diagnostic methods of viral
infections
12. Understand the concept anti-viral chemotherapy
13. Dfferentiate between DNA and RNA viruses
Teaching Methods:
Lectures
Self-readings
Homework
Tests and Evaluations: (Multiple choice questions) First Exam 25
Marks
Second Exam 25 Marks
Practical Exam 10 Marks (At the end of the course) Final Exam 40
Marks
Total 100 Marks
The Definitive Timetable of exams will be announced later.
Make up exams:
Students who are absent in any exam are allowed to sit a written
(Essay Questions) makeup exam after presenting an approved sick
leave or any approved certificate of absence. Those absents who do
not present a clue will be given a zero mark.
Discipline:
All students are expected to be quiet in their seats in the
lecture theatre before the start of the lecture. Engagement in
class discussions is encouraged without side chatting.
Cell phones are not allowed to be used during lectures and exams
unless prior approval
has been taken from the course instructor.
Labs Topics
1. Laboratory Safety, Microscopy, Aseptic Technique
2. Bacterial Cultures, Slide Preparation, Staining,
Streaking
3. Streaking, Pour Plates
4. Bacterial Characteristics
5. Differential and Selective Media, IMViC Test
6. Bacterial Identification
7. Litmus Milk, Carbohydrate Fermentation, Hydrogen Sulfide and
Agglutination Tests
8. Further Tests
Course Contents and Schedule:
Topic No. of Lectures
1. Introduction to Microbiology, Bacterial Cell Structure 3 and
Nutrition and Growth of Bacteria.
11. Vibrios, Campylobacter and Helicobacter
1
12. Brucella and Yersinia
1
13. Mycobacteria
1
14. Rickettsia, Chlamydia and Mycoplasma
1
15. Spirochaetes, Bacteroides and non-sporing Anaerobes
1
16. Fungi
2
17. Introduction to Parasitology
1
18. Protozoa
2
19. Helminthes
2
Second Exam
20. Introduction to Virology
1
21. Viral Structure and Replication
2
22. Viral Genetics
1
23. Pathogenesis and Immunity to Viral Infections
2
24. Diagnosis of Viral Infections
1
25. Anti-Viral Agents
1
26. DNA Viruses
2
27. RNA Viruses
1
Final Exam
Total Lectures :
40
References:
- Jawetz, Melnick, & Adelberg's Medical Microbiology, Latest
Edition.
- Bailey & Scott’s Diagnostic Microbiology, Latest Edition
.
- Sherris Medical Microbiology, An Introduction to Infectious
Diseases, Latest
Edition.
- Microbiological methods, Collins and Lyne, Latest Edition.
Course title: Introduction to Pharmacology
Course number: 1504201
Credit Hours: 2 Credit Hours ( 2 Lectures / week)
Course Coordinator: Prof. Yacoub Irshaid
Objectives of the course:
This course should cover the following subjects,
Pharmacokinetics, Pharmacodynamics, dose response relationship,
drug toxicities and side effects, drug cost-benefit relationship,
principles of drug trials, principles of drug prescription,
principles of drug utilization, drug information facilities and
drug interaction, drug epidemiology, principals of
antimicrobial drugs, principals of anticancer drugs,
immunosuppressants.
1. Mention the different names and sources of drugs
2.Describe the different pharmaceutical preparations and methods
of drug administration.
3.Describe pharmacokinetic of drugs including absorption,
distribution, biotransformation (metabolism) and excretion .
4. Mention drug pharmacodynamics, in terms of structure activity
relationship and the action of drugs through different human body
targets such as ion channels, receptors, enzymes, macromolecules,
carriers. etc…..
5. Explain the effects of pharmacokinetics on pharmacodynamics
.
6. Discuss general strategies for maximizing the therapeutic
effects of drugs.
7. Describe how interactions between drugs and foods could be
minimized.
8. List the most serious adverse effects of drugs .
9. Write and read an ideal drug prescription
10.
11.
12.
13.
14.
15.
Differentiate the types of receptors in the autonomic nervous
system. Describe the effects of various drugs on the autonomic
nervous system. Correlate the effects of these drugs with their
clinical applications and toxicity.
Describe the actions of drugs on bacteria, viruses, fungi, and
parasites. Describe the primary therapeutic uses for the major
chemotherapeutic classes . Mention core antibacterial agents,
antiviral agents, anti-fungal agents and anti-
parasites agents, identify their doses, indications and side
effects .
Reference Books:
1. Modern Pharmacology, 6th edition, 2004
2. Rang and Dale Pharmacology, 2nd edition, 2003
3. Basic and clinical Pharmacology 7th edition, 1998
Tests & Evaluation:
Mid term course exam
40%
Quiz
10%
Final Exam
50%
Lectures :
A. General pharmacology:
1. Definitions in pharmacology
2. Pharmacokinetic principles
3. Routes of drug administration
4. Drug biotransformations
5. Pharmacodynamics
6. Receptors and postreceptor phenomena
7. Dose-response curves
8. Interindividual variation in drug response
B. Antibiotic and Chemotherapeutic agents:
1. Antimicrobial agents general consideration
2. Beta-lactam antibiotics
3. Other cell wall- active agents
4. Antifolate drugs and drugs used in treatment of urinary tract
infection
5. Aminoglycosides
6. Macrolide antibiotics
7. Tetracyclines, chloramphenicol, and other inhibitors of
protein synthesis
8. Antimycobacterial agents
9. Antifungal agents
10. Antiprotozoal agents: ameba, malaria and others
11. Anthelminthic Drugs
12. Ectoparasiticides
13. Introduction to antiviral
14. Introduction to cancer chemotherapy
C. Autonomic Nervous System agents:
1. General framework for the autonomic nervous system and
receptors.
2. Action of agonists and antagonist drugs on the sympathetic
system.
3. Action of agonists and antagonists, i.e. drugs on the
parasympathetic system.
4. Action of drugs on the ganglia.
Hashemite University
Faculty of Medicine
2nd year – second semester syllabus
COURSE TITLE : RESPIRATORY SYSTEM (RS) COURSE CODE : 1500201
CREDIT HOURS : 5
CALENDAR DESCRIPTION : 5 WEEKS/ 2nd Semester/ 2nd Year TEACHING
APPROACHES: INTEGRATED SYSTEM MODULE. COURSE COORDINATOR: Prof.
Faik Hussain Mohammed
I. GENERAL OBJECTIVES :
Upon completion of this course student should be able to:
1. Identify and describe structures of respiratory organs, as
well as their development, histology and blood supply.
2. Understand the mechanics of pulmonary ventilation and the
mechanisms involved in the regulation of respiration.
3. Explain how the respiratory gases are exchanged and
transported by the blood
4. Identify various bacteria, viruses, parasites and fungal
infections which infect the respiratory tract and to understand the
principles of diagnosis, treatment and prevention.
5. Identify and describe the causes, pathogenesis, morphological
changes and complications of various disease processes which affect
the respiratory tract.
6. Understand the pharmacological principles which provide the
basis for the treatment of tuberculosis, cough and bronchial
asthma, as well as the pharmacology of anti-histamine drugs.
7. Identify the major risk factors which contribute to
occupational diseases of the respiratory system and to understand
their epidemiological pattern in the Jordanian community.
II. METHODS OF INSTRUCTION:
- Lectures
- Practical classes
III. EVALUATION AND DISTRIBUTION OF MARKS:
- In-course theory exam = 40%
- In-course practical exam = 20%
- Final course theory exam = 40%
IV. RECOMMENDED TEXT BOOKS and ATLASES:
Anatomy:
- Clinical Anatomy by system. By R.S. Snell.
- Grants Atlas of Anatomy or any other reasonable colored atlas
of Human
Anatomy.
- Before we are born. By K.L. Moore and T.V.N. Persaud, 5th
edition 1998.
-Basic Histology, by L.Carlos Junqueira, 10th. Edition 2004/or
functional histology by Wheater (latest edition)
- Supplementary Departmental Handouts.
Clinical Biochemistry:
- Campbell, 2006 or latest edition.
- Supplementary Departmental Handouts.
Physiology:
- Textbook of Medical Physiology, by Guyton and Hall, 11th
edition.
-
- Supplementary Departmental Handout.
Clinical Microbiology:
- Medical Microbiology. An Introduction to Infectious Diseases.
By Sheries, latest
edition.
Pathology & Clinical Pathology Lab. :
- Basic Pathology, by Kumar, Cotran and Robbins, 8th. edition,
2007.
- Supplementary Departmental Handouts.
Clinical Pharmacology:
- Lipincott’s Illustrated Reviews: Pharmacology, 2nd edition,
2000.
LEARNING (SPECIFIC) OBJECTIVES OF THE MODULE: A. LECTURES:
Physiology Lectures
residual volume.
4. forced expiratory volumes and the differentiation between
obstructive & restrictive respiratory dysfunction
4
Ventilation
1. describe pulmonary and alveolar ventilation
2. does all the inspired air participate in gas exchange, the
anatomic and physiologic dead spaces.
3. effect of breathing patterns on alveolar ventilation
4. the mechanism of regional differences in ventilation.
5
Pulmonary circulation
1. compare the pulmonary and systemic circulations
listing the main differences between them.
2. characterize pressures in the pulmonary system
3. describe the uneven distribution of blood flow through the
lungs
4. describe the fluid balance mechanism of pulmonary edema
6
Physical principles of gas exchange
1. describe the concept of gas partial pressure.
2. mention PO2 & PCO2 in inspired air, alveolar air, and
expired air.
3. mention the arterial and venous PO2 and PCO2.
4. discuss the diffusion of O2 and CO2 through the respiratory
membrane.
7
Ventilation/perfusion
relationship
1.describe the primary function of the lung, that is, gas
exchange
2. review three mechanisms of hypoxemia: hypoventilation,
diffusion limitation , and shunt
3. the concept of ventilation-perfusion inequality
4. examine how ventilation-perfusion inequality impairs overall
gas exchange
8
Transport of O2 by
the blood
1. describe the forms by which O2 is transported by the
blood.
2. discuss the O2 – hemoglobin dissociation curve.
3. describe factors affecting O2 – hemoglobin dissociation
curve.
4. Bohr effect
9
Transport of CO2 by
the blood
1. describe the forms by which CO2 is transported by
the blood.
2. describe Haldane effect.
10
Control of
ventilation
1. the central control of ventilation
2. the sensors; various chemoreceptors that provide the
respiratory center with information
3. describe the integrated responses to CO2, hypoxia, and pH
4. regulation of ventilation in chronic respiratory failure
Anatomy Lectures
#
Title of
Lecture
Lectures outline
1
Overview of
Anatomy of the Respiratory System
1.Describe the general structures and organs of the respiratory
system.
2.Compare and relate the structure and function of thedifferent
components of the respiratory system.
3. Understand the essentials of the respiratory system
4. Describe the anatomical and functional subdivisions of
the
Respiratory system.
2
&
3
Upper
Respiratory System: External nose, Nasal Cavity, Pharynx,
Lower Respiratory System: Larynx
1. Describe the structure of the external nose with its blood
and nerve
supply.
2. Describe the structure of the nasal cavity including the
nasal septum.
3. Locate the openings of the paranasal sinuses and
naso-lacrimal duct in the meatuses.
4. Describe the nerve and blood supply of the nasal cavities,
and its relation to epistaxis.
5. Study the structure of the nasopharynx, oropharynx, and
laryngopharynx and associated structures with their clinical
significance.
6. Describe the structure of the various cartilages and
membranes of the larynx.
7. Describe the muscles of the larynx, including their actions,
nerve and blood supply.
8. Study the structure of the vocal cords and the mechanism of
voice production.
4
Lower
Respiratory System: Pleura, lung and Mediastinum
1. Describe the trachea including its subdivisions and
relations.
2. Define pleura and pleural cavity, and name its parts and
recesses.
3. Discuss the nerve supply of the pleura.
4. Describe the lungs, their lobes, fissures and surfaces and
compare between right and left lungs.
5. Make a list of bronchopulmonary segments.
6. Describe the innervation, blood supply and lymphatic drainage
of the lungs.
7. Identify different parts and contents of the mediastinum.
8. Study the origin, location, course and branches of the
internal thoracic artery.
9. .Define the surface markings of the trachea, lungs and
pleura.
10. .Describe the typical appearance of chest X-ray
5
Thoracic cage,
Thoracic wall
& Respiratory muscles
1. Describe the shape and outline of the thoracic cage.
2. Describe the anatomical landmarks of the anterior chest
wall.
3. List the various structures making the thoracic wall.
4. Make a list of muscles of the thoracic wall including their
nerve, blood supply and actions.
5. Classify ribs, name their various parts.
6. Define intercostal spaces and discuss their various
components including intercostal muscles.
7. Describe the diaphragm, its origin, insertion, function,
nerve and blood supply. Study openings in the diaphragm and
structures pass through.
6
Histology of
Respiratory
System
1. Describe the microscopic structure of the upper respiratory
passage.
2. Correlate the structure and expected function of the nose,
pharynx larynx and trachea.
3. Study the microscopic structure of the main bronchi and their
subdivisions.
4. Study the microscopic structure of the lung parenchyma and
correlate this structure with gas exchange function.
7
Pre- and Post-
natal Development of Respiratory System
1. Describe the development of the nasal cavity.
2. Describe development of the pharynx and larynx.
3. Describe the development of the lungs and bronchi.
Clinical Biochemistry Lectures
#
Lectures
Title
Lectures outline
1
Acid-base
balance & the respiratory system
1. Describe the bicarbonate buffer system
2. Describe the biochemical changes in respiratory acidosis
&
Alkalosis
2
Role of
hemoglobin in acid base balance
1. Describe the role of hemoglobin in the buffer system
2. Describe the oxyhemoglobin dissociation curve
3
Phospholipid
Metabolism
1. Describe the biochemical structure, synthesis and role of
lung
surfactant in respiratory distress syndrome
2. Describe the functional role of α 1-antitrypsine in
maintaining lung elasticity, the molecular basis of emphysema
3. Describe the molecular basis of cystic fibrosis
4
Arterial Blood
Gases (ABG)
1. Describe the distribution of blood gases
2. Know the effect of increase or decrease of blood gases
Pathology Lectures
Lectures
No.
Lectures Title
Lectures outline
1
Obstructive
Lung diseases
(I)
Describe the Normal Alveolar Wall. Define Emphysema &
Chronic Bronchitis.
Describe the Etiology, Pathogenesis, Types, Pathologic (Gross
&
Microscopic) Features, Effects, & Complications Of The
Centrilobular & Panacinar Emphysema (E).
Define & Differentiate each of the following conditions from
true emphysema:
(1) Compensatory E, (2) Obstructive E, (3) Bullous E, & (4)
Mediastinal (interstitial) E.
2
Obstructive Lung diseases (II)
Describe the etiology, types, pathogenesis, pathologic
features,
effects & complications of:
(1) Chronic Bronchitis,
(2) Asthma, &
(3) Bronchiectasis.
3
Acute Respiratory Distress Syndrome & IPF
List the Disorders Associated With Acute Respiratory
Distress
Syndrome (ARDS).
Describe the Pathogenesis, Gross & Microscopic Features,
&
Effects of ARDS.
Classify the Major Categories Of Chronic Interstitial Lung
Disease, & Describe Its Pathogenesis.
Describe the Gross & Microscopic Features Of Idiopathic
Pulmonary Fibrosis (IPF).
4
Pneumoconioses
& Sarcoidosis
Describe the: Types, Pathogenesis, Gross & Microscopic
Changes, Effects & Complications of:
(1) Coal Workers' Pneumoconiosis, (2) Silicosis, & (3)
Asbestosis.
Define Drug-Induced & Radiation-Induced Pulmonary
Diseases
(acute radiation pneumonitis)
Describe the: Pathogenesis, Sites Of Involvement, Gross
&
Microscopic Features, Effects & Complications Of
Sarcoidosis
In The Lung & In The Other Organs
