Upload
ajmal-najeeb
View
36
Download
4
Tags:
Embed Size (px)
DESCRIPTION
mucositis case applied
Citation preview
Case Report
•A 47-year-old male patient
• Complains of burning sensation of mouth
•Duration-2 years
Chief Complaint
History of Presenting Illness
•History of diffuse large B cell lymphoma for which he underwent chemo and radiation therapy.
•He developed the present problem 3 months after the therapy.
•Numbness in the tongue.
Clinical Examination ExtraoralNo abnormality detected.IntraoralRevealed linear ulceration of size 2.5 x 1 cms covered by a yellowish white pseudomembrane on the buccal mucosa bilaterally at the level of the occlusal plane.
Right buccal mucosa
Provisional diagnosis:
• Erosive / Bullous lichen planus• Lichenoid reaction• Chronic ulcerative stomatitis• Chemotherapy induced oral mucositis
Histopathology
Superficial stratified squamous epithelium
(10x)
Histopathology
Sheets of plasmacytoid cells in the connective tissue40X
Histopathology
Cellular and nuclear pleomorphism
HISTOPATHOLOGY
Vesiculated and hyperchromatic nuclei
peripheral chromatin condensation
Immunohistochemistry Kappa and lambda
Kappa Lambda
Plasma cell mucositis / Chronic
ulcerative stomatitis
Plasma cell mucositis