Please Join Us for Tech Collective’s BioTuesday

Tuesday, November 8, 20115:30 pm to 7:00 pm

60 Clifford St, Providence RI

www.nabsys.com

NABsys is a life sciences company working at the intersection of physics, biology, and computer science to revolutionize medicine through clinical-

grade whole-genome DNA sequencing. NABsys is one of five companies to receive a “$1000 Genome” award from the National Human Genome

Research Institute of the National Institutes of Health.

NABsys CEO Barrett Bready, MD, and other members of the NABsys team will be speaking and answering questions.

Go to www.tech-collective.org to register. This is a FREE Event.

Drinks and Hors d’ Oeuvres will be served.

Parking is available at the building.

NABsys is a life sciences company working at the intersection of physics, biology and computer science to develop its proprietary electronic solid-state DNA sequencing platform. The company has assembled a world-class team that includes scientific pioneers, successful entrepreneurs and executives, and a staff of leading edge scientists and engineers. NABsys was the first company to receive a “$1000 Genome” award from the National Human Genome Research Institute of the National Institutes of Health for an electronic approach to sequencing.

The annual market for DNA sequencing is >$2 billion and growing, with applications in basic research, drug discovery, diagnostics, and agriculture. Companies are competing on throughput and cost, both of which are improving, but not sufficiently for major market growth. Current “next generation” sequencing systems will have difficulty scaling to meet future needs, and perhaps more importantly, have fundamental performance limitations that result in relatively poor data quality, sequence gaps, and incorrect data assembly. Scientists currently accept poor data quality in the absence of any alternative. While advances in research are being made, opportunities for major discoveries are being missed, and clinical utility is limited.

NABsys’ technology is designed to set new standards of performance by offering scientists orders of magnitude improvements in accuracy, speed, cost and scalability of genome sequencing. The same platform enables other forms of DNA analysis, such as targeted gene sequencing and characterization of genome structural variation. NABsys’ solution will for the first time provide the level of performance and scalability required for widespread use of genome sequence data in the clinic, and will expand the market for sequence analysis in research, drug discovery, diagnostics and agriculture.

Leadership TeamBarrett Bready, MD, CEO– 2011 Rhode Island Innovator of the Year– Adjunct Professor of Biotechnology at Brown University– MD from Brown Medical School – ScB in Physics from Brown University

John Oliver, PhD, VP R&D– Previously Chief Scientific Officer and Co-Founder at GeneSpectrum, and Assistant Professor of Chemistry at Brown University– PhD in chemistry from Northwestern University – BS in chemistry from Harvey Mudd College

Steve Nurnberg, VP, Engineering– More than 35 years experience in creating and commercializing life science instrumentation. Held senior management and technical leadership positions at IDEX Health & Science, Perkin-Elmer/Applied Biosystems, Millipore/Waters and Corning Medical– BSEE, Cornell University

Richard Hollingsworth, VP Semiconductor Technology– Former Semiconductor Wafer Fabrication Plant Manager, Intel (INTC); VP, Manufacturing and Operations, Semiconductor Sector, Motorola (MSI)– 11 US Patents– University of Pennsylvania, MSEE– Princeton University, BSEE

David Bernstein, BS, JD, General Counsel & Chief IP Counsel– Registered Patent Attorney, U.S. Patent & Trademark Office– Former General Counsel & Chief IP Counsel at Javelin Pharmaceuticals and U.S. Genomics; Partner, Co-Founder of IP Section, and Chair of IP Section at Mintz Levin Cohn Ferris Glovsky and Popeo– J.D. Franklin Pierce Law Center (now University of New Hampshire School of Law)– B.S. Engineering Science, Yale University

Leroy Hood, MD, PhD, Director– President, Institute for Systems Biology– Pioneering inventor of four instruments - the DNA gene sequencer and synthesizer, and the protein synthesizer and sequencer, which comprise the technological foundation for contemporary molecular biology – Member of the National Academy of Sciences, the American Philosophical Society, the American Association of Arts and Sciences, and the Institute of Medicine. Founder of numerous biotechnology companies, including Amgen (AMGN) and Applied Biosystems (LIFE)– MD from Johns Hopkins School of Medicine – PhD in Biochemistry from the California Institute of Technology

Stan Rose, PhD, Director– President of Rose Ventures, Inc.– Former CEO of NimbleGen Systems, Inc., acquired by Roche in 2007; Co-founder and COO of Genetic MicroSystems, acquired by Affymetrix (AFFX) in 2000; Director of PCR business for Perkin-Elmer and ABI (LIFE) – PhD from the Massachusetts Institute of Technology– BA from Cornell University

Ray Stata, Director– Founder and Chairman of Analog Devices (ADI)– Founder of Stata Venture Partners– Vice Chairman of the Semiconductor Industry Association– Member of the MIT Corporation, the American Academy of Arts and Sciences and the National Academy of Engineering Recipient of the 2003 IEEE Founder’s Medal– BSEE and MSEE from the Massachusetts Institute of Technology

Scientific Advisors:George Church, PhD, Harvard UniversityFranco Preparata, PhD, Brown UniversityJohn Quackenbush, PhD, Dana-Farber Cancer InstituteJeffrey Sklar, MD, PhD, Yale UniversityEli Upfal, PhD, Brown University

Milestones in Corporate Growth 2004: Founded

– Initial support from Brown University and Slater Technology Fund

2007: Merged with GeneSpectrum– Launched current business

– Occupied incubator space at Richmond Square

2009: $4M Series A financing– Moved to 349 Eddy St., 4,000 square feet, 10 employees

2010: $7M Series B financing– Moved to 60 Clifford St., 10,000 square feet, 20 employees

2011: $10M Series C financing– We are expanding to 14,000 square feet, 35 employees and growing