Living and Dying with CancerAngela Armstrong-CosterUniversity of Southampton, UK‘… allows us a glimpse of some of the most personal and sensitive issues … there are important messages for those who work in medical oncology and palliative care …’The value of this book is in what the patients have to say. Anyone who works in palliative care will benefit from listening to them and it should be required reading for anyone training in medical or radiation oncology.’International Association for Hospice and Palliative Care 5e-Newsletter

2004 208pp 978 0 521 54667 6 (0 521 54667 2) Paperback £15.99

Breast Cancer OnlineBreast Cancer Online (BCO) is a peer-reviewed educational service made freely available to healthcare professionals working in the numerous fields of breast cancer research and treatment. The content of the website is invited and reviewed by an independent international editorial board of experts from a multi-disciplinary perspective. For further information, visit the journal homepage at: www.journals.cambridge.org/jid_BCO

Journal of Radiotherapy in PracticeA peer-reviewed journal covering all of the current modalities specific to clinical oncology and radiotherapy. The journal aims to publish research from a wide range of styles and encourage debate and the exchange of information and opinion from within the field of radiotherapy practice and clinical oncology. www.journals.cambridge.org/jid_JRP

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The book industry is moving to a 13 digit ISBN numbering system. When ordering during the current transition period, quote the 13 digit or the 10 digit ISBN.

Printed in the United Kingdom at the University Press, Cambridge May 2006

Please order from your local bookseller

Contemporary Issues in Cancer Imaging Imaging is pivotal in all aspects of the management of patients with cancer; all members of the multidisciplinary team managing the cancer patient should understand the potential applications, limitations and advantages of imaging techniques, and the radiologist should have sufficient knowledge of the pathology, clinical background, therapeutic options and prognostic indicators of different tumours to understand the significance of imaging findings.

Each volume in Contemporary Issues in Cancer Imaging will be dedicated to a single tumour site and edited by recognised guest expert editors. The series will bring together expertise from radiologists, oncologists, pathologists, surgeons, basic scientists and others to not only promote the understanding and rational application of modern imaging but also help in the overall management of patients with cancer.

Series editors: Rodney Reznek and Janet Husband

Forthcoming

Carcinoma of the OvaryRodney H. ReznekSt. Bartholomew's Hospital, London, UKOvarian cancer is the commonest and most lethal gynaecological malignancy, partly because the majority of patients present with advanced disease. The management of patients with ovarian neoplasms has changed substantially, with improved survival due to better screening strategies, major advances in chemotherapy and the constantly evolving role of surgery. Optimal patient care is best achieved by a multidisciplinary team, with imaging playing a pivotal role. The explosion of technological developments in imaging in recent years means that all members of the team should understand the potential of these imaging techniques.

Features• Multidisciplinary approach makes it suitable for a wide range of clinicians

• Highly illustrated with all imaging and pathology modalities

• Unique text will appeal to the whole team of radiologists, oncologists and surgeons

Contents: Series foreword; Preface; 1. Epidemiology of ovarian cancer; 2. The pathological features of ovarian neoplasia; 3. Ovarian cancer screening; 4. Surgical management of patients with epithelial ovarian cancer; 5. Medical treatment of ovarian carcinoma; 6. Ultrasound in ovarian carcinoma; 7. MR Imaging in ovarian cancer; 8. CT in carcinoma of the ovary; 9. PET and PET/CT in ovarian cancer.

December 2006 232 pp 123 illustrations

978 0 521 86323 0 (0521 86323 6) Hardback c.£45.00

Forthcoming in the series in 2007

Colorectal CancerDr Gina Brown Royal Marsden Hospital, London, UK

This second volume in the Contemporary Issues in Cancer Imaging series provides a comprehensive summary of the latest developments in imaging and management of colorectal cancer.

Chapters on screening, MRI, CT and ultrasound imaging, staging, pathology and clinical management (surgery, chemoradiotherapy) are complemented by chapters on imaging for hepatic resection, patterns of recurrence and developments in laparoscopic surgery. All members of the multidisciplinary clinical team will find this an invaluable resource in daily practice. January 2007 200pp 150 illustrations 978 0 521 69291 5 (0 521 692911) Hardback £45.00

Lung CancerDr Sujal DesaiKing’s College Hospital, London, UKLung cancer is the second most common cancer in the UK and the leading cause of cancer deaths in the USA. Recent advances in chest imaging have improved the accuracy of tumor staging, and screening for lung cancer in high-risk populations is now performed.

This third volume in the Contemporary Issues in Cancer Imaging series summarizes the latest developments in the field, emphasizing the multidisciplinary approach to the care of patients with lung cancer. In addition to chapters on the radiological issues surrounding the diagnosis and staging of lung cancer there are individual chapters on clinical considerations, histopathology, surgery, radiotherapy and systemic chemotherapy in lung cancer.January 2007 200pp 150 illustrations 978 0521 87202 7 (0 521 87202 2) Hardback £45.00

Information is correct at time of going to press but is subject to change without notice.

Introducing a new series

Childhood Leukemias2nd editionEdited by Ching-Hon PuiSt. Jude Children’s Research Hospital, Memphis, USAChildhood leukemias represent nearly one third of all cancers in children and present a unique challenge to oncologists, pediatricians, hematologists, and other health professionals. An expert team of authors have assembled the most comprehensive, clinically-oriented, and authoritative reference dedicated to these diseases. Childhood Leukemias moves from the laboratory bench to the patient bedside in four easily-accessible sections. Childhood Leukemias is an absolute ‘must-have’ for any physician or investigator who deals with leukemias in childhood.

Review from the lst edition‘I would not hesitate to recommend this book to pediatric oncology and hematology units and to refer trainees to several of the excellent chapters. I would certainly have appreciated access to it during my training.’The New England Journal of Medicine

Features• Comprehensive text with judicious blend of clinical and biological topics

• New chapters on chemoresistance, advances in therapy-related leukemias, antibody-targeted therapy, pain management, genetic predisposition and treatment possibilities in countries with limited resources

• Written by leading international experts in the field of childhood leukemias

Contents: Part I. History and General Issues; Part II. Cell Biology and Pathology; Part III. Evaluation and Treatment; Part IV. Complications and Supportive Care.

2006 928pp 442 illustrations 978 0 521 82519 1 (0 521 82519 9) Hardback £170.00

The Economics of Cancer CareNick BosanquetKarol SikoraBoth from Imperial College School of Medicine, London, UKThis book examines the interaction of economics and the delivery of cancer care in the global context. It analyses tensions between those paying for care, those providing the care and those marketing drugs and devices. As cancer increases in incidence and prevalence, the economics of providing care becomes a more important subject than ever before. Written by a leading health economist and oncologist, this is the first comprehensive book on the economics of cancer care and is essential reading for health professionals and policy makers alike.

Features• Provides a crisp, concise analysis of the economics of cancer care

• Covers both the prevention and treatment of cancer

• Discusses the likely impact of future treatment and management strategies

Contents: 1. Introduction; 2. Prevention; 3. Screening; 4. Diagnostics; 5. Surgery; 6. Radiotherapy; 7. Chemotherapy; 8. Moving towards the new model: international comparison; 9. The new agenda; 10. Cancer’s economic impact on society; 11. Improving the patient experience.

2006 192 pp 36 illustrations 978 0 521 85007 0 (0 521 85007 X) Hardback £55.00

Oncology

SPECIaL InTRODuCTORy PRICE £155.00 Until 31 July 2006,

thereafter £170.00

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Textbook

The Biological Basis of Cancer2nd editionRobert G. McKinnellUniversity of Minnesota, USARalph E. ParchmentWayne State University, USAAlan O. PerantoniNational Cancer Institute, Bethesda, Maryland, USAIvan DamjanovUniversity of Kansas, USAand G. Barry PierceUniversity of Colorado Medical Center, USADesigned to be used for an undergraduate course on cancer biology, this book is aimed at upper division undergraduates with a background in biology, as well as beginning graduate students. An introduction acquaints students with the biological principles of cancer, and the human dimensions of the disease by considering genuine cases of cancer. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer and a glossary.

Features• Written specifically for a first course in cancer biology,

taking into consideration the backgrounds of students at this level

• Uniquely covers all aspects of the subject from molecular biology to clinical considerations and the biological basis of treatments

• Extensively updated to include new techniques, treatments and epidemiological evidence

Contents: Preface; Introduction: letters illustrating clinical aspects of cancer; 1. The pathology of cancer; 2. Metastasis; 3. Carcinogenesis; 4. Cancer genetics; 5. Oncogenes and suppressors; 6. Cancer in organisms other than humans; 7. Epidemiology; 8. Cancer treatment; 9. Biological therapy; Appendices: A. Description of selected tumors; B. Glossary; References; Index.

July 2006 400pp 148 illustrations 978 0 521 60633 2 (0 521 60633 0) Paperback £29.99

978 0 521 84458 1 (0 521 84458 4) Hardback £65.00

Cancer PainAssessment and ManagementEdited by Eduardo D. BrueraUniversity of Texas, M. D. Anderson Cancer Center, UKand Russell K. PortenoyBeth Israel Medical Center and Albert Einstein College of Medicine, New York, USANearly one in three people will be diagnosed with cancer, and many of these patients will suffer from related cancer pain. Cancer-associated pain is widely feared by cancer patients, but knowledge about the causes and management of cancer pain has increased dramatically in recent years and many new treatment options are available.

This comprehensive book discusses the unique characteristics of cancer pain, including its pathophysiology, clinical assessment, diagnosis, pharmacological management and nonpharmacological treatment. The internationally recognized authors are leaders in cancer pain research, and they apply their first-hand knowledge in summarizing the principal issues in the clinical management of cancer pain. It cohesively addresses the full range of disciplines regularly involved in cancer pain management, including pharmacology, communication studies, and psychology.

‘… this is an excellent book. It presents a vast array of information in a clear, accurate and accessible fashion, which is relevant to the non-specialist and specialist alike … it represents very good value. In producing a textbook on cancer pain, the editors’ stated aim was to provide a ‘comprehensive, clinically oriented, and scholarly review of all aspects of this complex and multidimensional problem’. They have succeeded admirably.’Palliative Medicine

Contents: Part I. Mechanisms and Epidemiology; Part II. Assessment and Syndromes; Part III. Pharmacological Treatment; Part IV. Non-Pharmacological Approaches; Part V. The Role of Antineoplastic Therapies in Pain Control; Part VI. Pain in Special Populations; Part VII. Difficult Pain Problems; Part VIII. Special Topics.

2003 500pp 65 illustrations 978 0 521 77332 4 (0 521 77332 6) Hardback £140.00

Handbook of advanced Cancer CareEdited by Michael J. Fischand Eduardo BrueraBoth from MD Anderson Cancer Center, University of Texas, USAPatients with advanced cancer increasingly receive end-of-life care from a variety of health care professionals, physicians and nurses. This is the first comprehensive source of information available to these professionals at a level between specialist oncology texts and nursing texts. Two eminent physicians from one of the world’s foremost cancer centers have drawn together a remarkable team to provide a handbook which covers the full range of problems non-specialists will encounter. This highly accessible text covers general principles in oncology, the primary tumors, and management of specific symptoms and syndromes.

‘The purpose of this excellent book is to provide up to date information for the nonspecialist on the treatment of the different cancers and the management of the various symptoms that can arise during treatment … it provides a very useful single source to enable the nonspecialist (GP, practice nurse, general physician/surgeon) to quickly get an overview of an individual cancer … the book is accessible, easy to read and has a comprehensive index. This book fills a large gap in the market and will be of great interest to GPs, General Physicians and Surgeons, Medical Students and both Hospital and Primary Care Nurses, for all of whom it represents very good value for money … will become a well established and successful text.’Palliative Medicine

Contents: Part I. Reasons for Breast Consultation: 1. Benign tumors; 2. Malignant tumors; 3. Pain; 4. Symptoms of the nipple areola complex; 5. Skin symptoms; Part II. Multidisciplinary Roles in the Treatment of Breast Lesions: 6. Role of the clinician; 7. Role of the radiologist - diagnostic; 8. Role of the radiologist - intervention; 9. Role of the pathologist; 10. Role of the surgeon - biopsies; 11. Surgical treatment of benign breast lesions; 12. Surgical treatment of malignant breast lesions; 13. Role of the plastic surgeon.

2003 532pp 112 illustrations 978 0 521 01043 6 (0 521 01043 8) Paperback £48.00

www.cambridge.org/medicine

Common Breast LesionsA Photographic Guide to Diagnosis and TreatmentEdited by Samuel PilnikLenox Hill Hospital, New York, USAThis generously illustrated color atlas provides a step-by-step guide to the differential diagnosis and treatment of both benign and malignant diseases of the breast. Organized around primary patient complaints, the atlas provides a multidisciplinary review of the respective techniques of the clinician, radiologist, pathologist, surgeon, and reconstructive surgeon. Coverage includes proper clinical examination, diagnostic and interventional radiography, diagnostic pathology, surgical biopsy, excision of benign lesions, mastectomy, breast conservation surgery, and reconstructive surgery. Clinicians will find this guide invaluable in diagnosing and treating the most common cancer affecting women today.

Features• Generously illustrated full-colour atlas with over 750

photographs, drawings, radiographs, and mammograms

• Step-by-differential-step clinical diagnosis of the most common benign and malignant breast lesions every practitioner should know

• Multidisciplinary focus integrates role of clinician, pathologist, radiologist, surgeon, and reconstructive plastic surgeon in managing breast disease

Contents: Part I. Reasons for Breast Consultation: 1. Benign tumors; 2. Malignant tumors; 3. Pain; 4. Symptoms of the nipple areola complex; 5. Skin symptoms; Part II. Multidisciplinary Roles in the Treatment of Breast Lesions: 6. Role of the clinician; 7. Role of the radiologist - diagnostic; 8. Role of the radiologist - intervention; 9. Role of the pathologist; 10. Role of the surgeon - biopsies; 11. Surgical treatment of benign breast lesions; 12. Surgical treatment of malignant breast lesions; 13. Role of the plastic surgeon.

2003 272pp 650 illustrations 978 0 521 82357 9 (0 521 82357 9) Hardback £120.00

Familial Breast and Ovarian CancerGenetics, Screening and ManagementEdited by Patrick J. MorrisonBelfast City Hospital, Belfast, IrelandShirley V. HodgsonGuy’s Hospital, London, UKand Neva E. HaitesUniversity of Aberdeen, Scotland ‘ … I found myself reading it from cover to cover. No chapter is weak … I recommend it to all clinical geneticists working in cancer genetics, to breast surgeons and gynaecologists who deal with these cancers, and to radiologists involved in screening programmes. It provides an excellent review of the state of the art, with all the relevant references’.Journal of the Royal Society of Medicine

2002 418pp 63 illustrations 978 0 521 01777 0 (0 521 01777 7) Paperback £33.00

Medical Therapy of Breast CancerEdited by Zenon RayterBristol Royal Infirmary, UKand Janine MansiSt George’s Hospital Medical School, University of London, UK‘The text is thorough, concise, and comprehensive to an extent which is consonant with its size. Factual information is pertinent, up-to-date, and presented with clarity and lack of bias. Controversial issues are discussed in a stimulating and non-dogmatic way with some insightful comments.’The Lancet

2003 412pp 12 illustrations 978 0 521 49632 2 (0 521 49632 2) Hardback £85.00

Outcomes assessment in CancerMeasures, Methods and ApplicationsEdited by Joseph LipscombNational Cancer Institute, Bethesda, Maryland, USACarolyn C. GotayCancer Research Center, Hawaii, USAand Claire SnyderNational Cancer Institute, Bethesda, Maryland, USACancer has profound effects on patients and families, but measuring outcomes such as quality of life poses unique challenges. This book provides perspectives on the state of cancer outcomes measurement and offers a penetrating discussion on a topic critically important to evaluating and enhancing the quality of cancer care.

‘This is an excellent and comprehensive book. … A strength of the book is the clear referencing to the vast literature reviewed which will provide a useful resource for student and seasoned expert alike …‘.Palliative Medicine

Features• Comprehensive review and synthesis of cancer

outcome measures and methods. Provides invaluable practical guidance to the cancer research manager or individual investigator about how to select high-quality measures of health-related quality of life and other patient-reported outcomes

• Individual chapters display empirical findings in lucidly presented tables, figures, and charts that facilitate side-by-side comparisons of alternative outcome measures and instruments

• Material accessible to a wide range of disciplinary backgrounds

2004 676pp 105 illustrations 978 0 521 83890 0 (0 521 83890 8) Hardback £95.00

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Case Studies in urological CancerAdrian N. HarnettNorfolk and Norwich University Hospital, UKRobert N. Meddingsand Brian McGlynnBoth at Ayr Hospital, UKWith Contributions by Stephen CooperAyr Hospital, UKand Bob NairnCrosshouse Hospital, Kilmarnock, ScotlandBuilds on the success of Dr Harnett’s previous Case Studies in Breast Cancer, which has established itself as a key title for anyone involved in diagnosis and care of the patient with breast cancer. Featuring over 30 detailed case studies, with comprehensive explanatory text and full colour illustrations, throughout, this book provides any healthcare professional involved in urological cancer with a selection of thought-provoking, practice-changing problems in this common malignant condition.

Features• Case study format gives access to important clinical

information in an easily understood and digestible way

• Multidisciplinary authorship reflects the nature of patient care

• Fully illustrated in full colour throughout·

• Structured text takes the reader through each case by presenting a series of questions and answers, in much the same way as they might work through a real clinical case

2003 160pp 60 colour illustrations 978 1 841 10138 5 (1 841 10138 9) Hardback £40.00

Case Studies in Breast CancerAdrian Harnett Western Infirmary, Glasgow, ScotlandFeaturing 37 detailed case studies, with comprehensive explanatory text and full colour illustrations, this book provides any healthcare professional involved in breast cancer with clear guidelines and helpful pointers on the aetiology, diagnosis and treatment of this important and widespread condition. All cases are based on real case encountered by the author, and provide the reader with realistic scenarios against which to judge their own their own treatment decisions and upon which to base teaching sessions.

Features• Case study format gives access to important clinical

information in an easily understood and digestible way

• Fully illustrated in colour throughout

• Structured text takes the reader through each case by presenting a series of questions and answers, in much the same way as they might work through a real clinical case

Contents:. Breast conservation or mastectomy?; 2. The influence of coexisting disease; 3. The difficult diagnosis; 4. Sequential bilateral breast carcinoma; 5. Genetic disease; 6. Cancer family syndrome; 7. HRT and other hormonal issues; 8. Adoption after breast cancer; 9. Breast cancer in pregnancy; 10. The doctor patient; 11. The high risk patient; 12. The unfit patient; 13. Pregnancy after cancer; 14. Neoadjuvant chemotherapy; 15. Acute illness; 16. Metastatic disease-or not?; 17. The internet patient; 18. Breast cancer and pregnancy; 19. Resistant inflammatory breast carcinoma; 20. Axillary lymphadenopathy; 21. The unusual tumour; 22. The professional sportswoman; 23. Late stage disease in pregnancy; 24. Hormone sensitive disease; 25. Receptor negative disease?; 26. Solitary bone metastases; 27. The orthopaedic challenge; 28. Aggressive metastatic disease; 29. Responsive metastatic disease; 30. Unusual sites of metastatic disease (1); 31. Unusual sites of metastatic disease (2); 32. The neglected tumour and unconventional management; 33. Extensive soft tissue disease; 34. Male breast cancer; 35. Spinal cord compression; 36. Recurrent spinal cord compression; 37. Brachial plexopathy (1); 38. Brachial plexopathy (2); 39. Brain metastases; Appendices; Index.

2001 160pp 100 colour illustrations

978 1 841 10054 8 (1 841 10054 4) Hardback £40.00

Gene Expression Profiling by MicroarraysClinical ImplicationsEdited by Wolf-K. HofmannCharite-University Hospital Benjamin Franklin, Berlin, GermanyMicroarray analysis is a highly efficient tool for assessing the expression of a large number of genes simultaneously, and offers a new means to classify cancer and other diseases. Gene expression profiling can also be used to predict clinical outcome and response to specific therapeutic agents. This survey spans recent applications of microarrays in clinical medicine, covering malignant disease including acute leukaemias, lymphoid malignancies and breast cancer, together with diabetes and heart disease. Investigators in oncology, pharmacology and related clinical sciences, as well as basic scientists, will value this review of a promising new diagnostic and prognostic technology.

Features• Introduces microarrays as a diagnostic and prognostic

technology

• Surveys clinical applications in a range of malignant and non-malignant diseases

• Leading edge scientists contribute from major centres

Contents: Preface; 1. Introduction; 2. Technique of microarrays: microarray platforms; 3. Quantitative quality control of microarray experiments: toward accurate gene expression measurements; 4. Statistical analysis of gene expression data; 5. Genomic stratification in patients with heart failure; 6. Gene expression profiling for the diagnosis of acute leukemias; 7. Gene expression profiling can distinguish tumour subclasses of breast carcinomas; 8. Gene expression profiling in lymphoid malignancies; 9. MRNA profiling of pancreatic beta cells: investigating mechanisms of diabetes; 10. Prediction of response and resistance to treatment by gene expression profiling.

July 2006 240pp 65 illustrations

978 0 521 85396 5 (0 521 85396 6) Hardback £80.00

FORTHCOMInG

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