7/24/2019 Po Honma Salah Demensia

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POHON MASALAH DEMENSIA aging, genetic factors

Neurofibrilary tangles

and filaments wrapped

around each other and

neurons in cerebral cortex

Loss of neurons

erebral atrophy

!idening sulci

Senile pla"ues

#educed white matter

$entri%ular dilatation

&rano'ascular body

Inade"uate blood

flow to brain

Decreased acetyl

cholinesterase and

choline acetyltranferase

Memory impairmanet

Decreased intellectual functioning

(orgetfulness

onfusion

ogniti'e impairmanetDeterioration in personal habits)social beha'ior

Aphasia, apraxia, agnosia

*yperexcitability

&ait disturbance

+otal dependence

Decreased of heart function

Atheros%lerosis

Decreased of

neurotranmiter

Altered thought

processes Sleep pattern

disturbance

Impaired 'erbal

communication(unctional

incontinence

Sexual dysfunction