Pradaxa IntroductionPradaxa Introduction(Indications for Use)(Indications for Use)

Learning ObjectivesLearning Objectives

A-Fib/StrokeA-Fib/Stroke

PharmacokineticsPharmacokineticsAbsorption

Distribution

Metabolism

Elimination

PharmacodynamicsPharmacodynamics

Dosage & AdministrationDosage & Administration

Recommended Dosage

Missed Doses

Renal Function

Pradaxa: EfficacyPradaxa: Efficacy

Pradaxa: EfficacyPradaxa: Efficacy

SafetySafety

SafetySafety

Contraindications For UseContraindications For Use

Warnings & PrecautionsWarnings & Precautions

Adverse ReactionsAdverse Reactions Increased GI Reactions

Gastritis –like Symptoms

GERD

Abdominal pain

GI bleed

GI Ulcer

Patient Counseling/EducationPatient Counseling/EducationInstruct patient on:

Signs & Symptoms of Bleeding

GI Adverse Reactions

Invasive or Surgical Procedure

Concomitant Medications

QueryQueryWith the positives and

negatives in the literature on this drug, would you, as a clinician, use Pradaxa as an alternative to Coumadin with your patients with a history of non-valvular A-fib?

Thank You!!!!Thank You!!!!