PROSTATITIS

DEFINISI

• Penyakit akibat inflamasi pada kel.prostat

Infeksi sal.urinari.• Gejala iritaif nyeri pada perineum,

suprabubis, penis, testis, inguinal, dan punggung bawah.

ETIOLOGI

• Infeksi• Imunogen• Toxin• Trauma• Stress

ETIOLOGI• Bakteri gram negatif :– Enterobacter family : E coli 65% - 80%– E coli 65-80%– Ps. Aeruginosa– Serratia– Klebsiella– Enterobacter aerogenes

• Bakteri grsm positif :– Enterococci 5-10%– Staphylococcus saprophyticin– Staphylococcus aureus

PATHOGENESIS

Initiation Response Facilitation Propagation Outcome

InfectionImmunogenToxinTraumaStress

Inflammation

Neurologic “injury”

Neuroendocrine me chanisms

Immunologic

Neurogenic

Neuropathic pain

(Nickel 2007)

Klassifikasi Prostatitis Sindrome

Traditional National Institutes of Health

Description

Acute bacterial prostatitisChronic bacterial prostatitis

Nonbacterial prostatitis

Prostatodynia

Category ICategory IICategory III Chronic Pelvic Pain Syndrome (CPPS)

Category IIIA (Inflammatory CPPS)

Category IIIB (Noninflammatory CPPS)

Asymptomatic Inflammatory Prostatitis (AIP)

Acute infection of the prostate glandChronic infection of the prostate glandChronic genitourinary pain in the absence of uropathogenic bacteria localized to the prostate gland employing standard methodologySignificant number of white blood cells in expressed prostatic secretions, post-prostatic massage urine sediment (VB3), or semenInsignificant number of white blood cells in expressed prostatic secretions, post-prostatic massage urine sediment (VB3), or semen White blood cells (and.or bacteria) in expressed prostatic secretions, post-prostatic massage urine sediment (VB3), semen, or histologic specimens of prostate gland

(Nickel 2007)

Manifestasi Klinis• Lokal :Nyeri akutRetensi urin akut• Sistemik :DemamMalaiseMual, muntah

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