International workshop NO-CANCER 2018

Understanding Cancer Cell Biology

to improve Diagnosis and Therapy

Novara (Italy) October 28-29-30, 2018Amedeo Avogadro

SCHOOL OF MEDICINE

OPENING CEREMONYLOCAL ORGANIZERS

Ciro Isidoro, Gianluca Gaidano

With the financial support of

ORGANIZATIONAL AND TECHNICAL SUPPORTERS

ACADEMIC AND INSTITUTIONAL PARTNERS

2016

2017

WHAT IS THE CONFERENCE ABOUT

Despite the undeniable progress we have made in fighting cancerwe still do not know how to defeat this disease

DEFINITELY, IF WE WANT TO WIN THE BATTLE WE HAVE TO KNOW MORE IN DEPTH THE BIOLOGY OF CANCER CELLS

Major topics

Metabolism (sugar, fat, aminoacids) of cancer cells

Metabolic cross-talk between cancer cells and stromal cells

The role of stroma and of immune response in Cancer.

Oncogenes, oncosuppressors and Non Coding RNAs in Cancer

development

Role of diet and of microbiota in cancer progression and response to

therapy

Novel strategies for early non-invasive detection of cancer

Innovative strategies for cancer therapy.

Clinical trials

13.45 – 15.45 Second Session CHAIRS: F. Baltazar, D. Dhanasekaran

- Laurent Schwartz (Paris, France): Alleviating the Warburg effect: preliminary

clinical results in advanced malignacies resistant to chemotherapy

- Rainer Klement (Schweinfurt, Germany): Fasting, fats and physics - adding a

ketogenic diet to radiotherapy against cancer

- Cyril Corbet (Brussels, Belgium): Blocking the mitochondrial pyruvate carrier to

inhibit lactate uptake by cancer cells and induce tumor radiosensitization

- Two Short communications: selected from abstracts

15.45 – 16.00 Coffee break

Tuesday October 30th SCIENTIFIC PROGRAM

- 09-00-09.30 Registration (slide upload)

09.30-11.40 Fourth Session CHAIRS: C Corbet, J. Menendez

- Gianluca Gaidano (Novara, Italy): Liquid biopsy and molecular

diagnosis in Leukemia

- One short communication: selected from abstracts

- Roberto Gambari (Ferrara, Italy): Peptide nucleic acid-based

targeting of microRNAs: possible therapeutic and diagnostic

applications for Glioblastoma

- Two short communications: selected from abstracts

11.15 – 11.35 six FLASH COMMUNICATIONS CHAIR: C. Isidoro

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11.40 – 11.55 Concluding Remarks

– CLOSING CEREMONY (Acknowledgements) C. Isidoro

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12.00 – 13.00 Farewell LUNCH (only registered participants)

International workshop NO-CANCER 2018

Understanding Cancer Cell Biology

to improve Diagnosis and Therapy

Novara (Italy) October 28-29-30, 2018Amedeo Avogadro

SCHOOL OF MEDICINE

CLOSING CEREMONYLOCAL ORGANIZERS

Ciro Isidoro, Gianluca Gaidano

With the financial support of

ORGANIZATIONAL AND TECHNICAL SUPPORTERS

ACADEMIC AND INSTITUTIONAL PARTNERS

Coming Special Issue “Biogenesis and functional roles of Lysosomes: implication in the pathogenesis and therapy of human diseases”Dear Colleagues,This Special Issue welcomes both original papers and review articles addressing the biogenesis and pathophysiological roles of lysosomes as specified on the homepage referred to above. In this Special Issue of IJMS, we want to offer a platform for high-quality publications on various aspects of Lysosome Biology. Topics include, but are not limited to:• Biogenesis of acidic compartments and their function in the cell• Trafficking of molecules and membranes among the endosomal-lysosomal organelles• Endocytosis and Exocytosis in cell communication• Biogenesis and function of exosomes• Lysosomes in cell survival and cell death pathways• Lysosomes and Autophagy• Lysosomes in development and embryomorphogenesis• Dysfunctional lysosomes in Human pathologies, with a special focus on autoimmune diseases, neurodegenerative diseases, lysosomal storage diseases, and cancer• Lysosomes as a therapeutic target in human diseases• Replacement gene therapy for lysosome dysfunctionProf. Ciro IsidoroGuest Editor

Website: coming soonSubmission deadline: 2019IJMS Editorial Office: ijms@mdpi.com/nicole.peng@mdpi.com

and OTHERS

THOMAS N SEYFRIED

HONORARY LECTURE

ACKNOWLEDGEMENTS TO THE PERSONS WHO HAVE REALLY DONE THE JOB

On behalf of the Organizing Committee, I wish to thank …

all the Speakers for having accepted the invitation, despite the short notice time and their busy schedule.

We thank the School of Medicine of Università del Piemonte Orientale and the University-Hospital “Maggiore della Carità” for hosting the event.

Special Thanks are due to the sponsoring Charity “Associazione italiana per la lotta contro Leucemie, Linfomi e Mielomi” di Novara (AIL) for the collaboration and support.

I am personally in debt to the Institutions that offered their kind support in the organization of the social events, and more in particular with the Municipality of Novara, the Agenzia per il Turismo Locale, the Conservatorio Musicale, the Fondazione Teatro “Carlo Coccia”, the Istituto Professionale G. Ravizza, and the Tipografia Italgrafica

More than one hundred and seventy participants have attended the Conference.

We are grateful to the Molecular Pathology Lab staff for their invaluable help in the practical management of all the organizational issues that such enthusiastic participation has inevitably posed.

More than that, I wish to thank the many persons who helped and supported with their enthusiasm and their dedication.

Anche in questa occasione, come già per i due congressi precedenti “Basic to Translational Medicine 2016: focus on Cancer” e “NO-Cancer 2017”, ho sentito la vicinanza del Città di Novara e percepito il clima di entusiasmo e collaborazione per la buona riuscita dell’evento.

Il mio ringraziamento alle Istituzioni, Fondazioni, Associazioni e Aziende per il loro contributo e supporto nell’organizzazione.

Di seguito, le persone che hanno messo a disposizione il loro tempo e le loro energie cui va il mio ringraziamento personale: Il Direttore Generale dell’Ospedale Mario Minola e il suo staffIl Sindaco Alessandro Canelli, l’Assessore Emilio Iodice, Benedetta Baraggioli, Marina Pieroni e tutto lo staff del Comune di Novara; Maria Rosa Fagnoni dell’Azienda Turistica Locale; Corinne Baroni della Fondazione Teatro Carlo Coccia; Anna Belfiore, Alessandra Aina e Roberto Politi del Conservatorio; Loreta Guacci e Marina Lunghi dell’Istituto Professionale G. Ravizza;Francesco Martelli e Michele di ItalGrafica;Giusi Ferrari di Novarseti; Maurizio Pietroni e Francesco Cellerino dell’Ammnistrazione;Roberto Serra del Laboratorio informatico;Giorgio Sambarino dell’Ufficio Tecnico;e poi tutto lo staff del Laboratorio di Patologia Molecolare di ieri e oggi con Chiara, Alessandra, Eleonora, Andrea, Giulia, Carlo, Claudia, Letizia, Sara e Angelica.

and thanks to you all for your active participation and great contribution.

staff del Laboratorio di Patologia Molecolare di ieri e oggi con Chiara, Alessandra, Eleonora, Andrea, Giulia, Carlo, Claudia, Letizia,

Sara, Andrea e Angelica.

International workshop NO-CANCER 2018

Understanding Cancer Cell Biology

to improve Diagnosis and Therapy

Novara (Italy) October 28-29-30, 2018Amedeo Avogadro

SCHOOL OF MEDICINE

CLOSING CEREMONYLOCAL ORGANIZERS

Ciro Isidoro, Gianluca Gaidano

The International Workshop NO-CANCER2018 is now officially closed… and we can go to enjoy the Farewell Lunch buffet.