Problems observed andProblems observed and

Faced in film coatingFaced in film coating

RAISE BED TEMP. & AIR VOLUME.

REDUCE SPRAY RATE

USE OF CORRECT PLASTICISER

DYE CONCENTRATION

LAKE COLOUR QUALITY

REPLACE WORN PUNCHESCORRECT COMB.OF POLYMER STRENGTH

REDUCE PIGMENT RATIO

CORRECT RATIO OF POLY & PLASTI.USE DIFF. COMBINATION OF POLYMERS

*BLISTRING

* *FADING

CHIPPING * *

BRIDGING *

SOLUTIONSPROBLEMS

ANALYSIS OF REASONS

COATING PARAMETERS

FORMULATION OF FILM COATING MATERIAL

FILM COATING R.M.

TABLETING

SOLUTIONS

CONTROL SPRAY RATE & SPEED OF THE PANDRYING PARAMETERSTABLET WITHOUT FLAT SURFACECORRECT PIGMENT CONTENTQUALITY OF LAKE COLOURINCREASE SPRAY NOZZLE SIZE & AREA OF SPRAYBETTER HOMOGI. OF POLY & PLASTI.POOR ATOMISATION OF COATING SOLUTIONPOOR DISBUR. OF PIGMENTS GEN. SOLUBLE COLOURSREDUCE SPRAY RATEINCREASE PAN SPEED IMPROVE DRYING CONDITIONS

STICKING *

* *

* *

* *

* *

TWINNING

SPLITTING

UNIFORMITY

MOTTLING

PROBLEMS

ANALYSIS OF REASONS

COATING PARAMETERS

FORMULATION OF FILM COATING MATERIAL

FILM COATING R.M.

TABLETING

ANALYSIS OF REASONS

EXTEND STORAGE PERIOD AFTER COMPRESSION OF TABLETS BEFORE THE COATING PROCESSCORRECT COMB.AND STRENGTH OF PLASTICISERUSE INSTACOAT REDUCE PAN SPEED, INCREASE SPRAY RATESELECT INSTACOAT WITH HIGHER RECONSTITUTIONREPLACE SUPER DISINTEGRANT AND USE INSTA BIND IC-820INCREASE COMPRESSION FORCE, CHANGE CORE FORMULATIONUSE DIFF. COMBINATION OF POLYMERSUSE LOWER RECONSTITUTION LEVEL FOR COATING SOLUTIONINCREASE AUTOMISATION AIR PRESSURE

*

TABLETINGPROBLEMS COATING

PARAMETERS

FORMULATION OF FILM COATING MATERIAL

FILM COATING R.M.

SOLUTIONS

*ORANGE PEEL/

ROUGHNESS

CRACKING * *

CORE EROSION *

ROUGHNESS * HIGHER SOLID CONTENTS

PICKING *IN FBC/WC - PROPER FILTERATIONIMPROPER ROLLING EXTRA SLIDE BARS & BAFFLESENSURE CORRECT DISTANCE BETWEEN SPRAY GUN & TABLET BEDINCREASE WEIGHT GAIN INCREASE PAN SPEED / IMPROVE BAFFLESDYE CONCENTRATIONUSE INSTACOAT - SEAL COAT (TRANSPARANT)

COLOUR VARIATION

* *

EDGEWEAR *

SOLUTIONSPROBLEMS

ANALYSIS OF REASONS

COATING PARAMETERS

FORMULATION OF FILM COATING MATERIAL

FILM COATING R.M.

TABLETING

1.1. Raise Bed TemperatureRaise Bed Temperature2.2. Raise Process Air VolumeRaise Process Air Volume3.3. Reduce Spray RateReduce Spray Rate

1. Correct Plasticiser

2. Dye Concentration

1. Lake colour quality

• Replace Worn PunchesReplace Worn Punches

1.1. Correct Combination Correct Combination of Polymer strengthof Polymer strength

2. 2. Reduce Pigment RatioReduce Pigment Ratio

1.Correct Ratio of Plasticiser & 1.Correct Ratio of Plasticiser & Polymers. Polymers.2. Use Combination2. Use Combinationof Different polymersof Different polymers

1.1. Control Spray RateControl Spray Rate2.2. Control Speed of the PanControl Speed of the Pan3.3. Drying ParametersDrying Parameters

1.1. Tablets withoutTablets withoutFlat surfaceFlat surface

1.1. Correct Pigment contentCorrect Pigment content2.2. Improve Film StrengthImprove Film Strength

1.1. Quality of Lake ColourQuality of Lake Colour2.2. Quality of PlasticizerQuality of Plasticizer

1.1. Check Spray nozzle size / Droplet Check Spray nozzle size / Droplet sizesize

1.1. Better homogenization ofBetter homogenization ofPolymers / Plasticizers / PigmentPolymers / Plasticizers / Pigment

1. Check Spray nozzle size1. Check Spray nozzle size

1. Better dispersion of pigments

1. Reduce the spray rate .2. Lower the Solid content .

1. Reduce spray rate2. Improve drying condition3. Increase pan speed

1. Check slide bars and baffles

2. Ensure proper rolling oftablets to provide uniform coating