Innovative Mass Spectrometry and Analytical System Solutions

Product Overview

Innovation with IntegrityGC/LC/MS-Systems

rapifleX™MALDI Tissuetyper™

For Mass Spectrometry Imaging

The rapifleX MALDI Tissuetyper solution is a powerful Mass Spectrometry Imaging (MSI) tool based on MALDI Time-of-Flight Technology. rapifleX is the first MS system, which is specifically designed according to the particular requirements of tissue typing with regard to speed, robustness and pixel definition.

Tissue sections that were analyzed in the Tissue-typer can still be histologically stained afterwards. The MALDI Imaging dataset can be overlaid with a microscopic image for detailed annotation.

rapifleX MALDI Tissuetyper is up to 20x faster than any other MS-imaging solution and therefore ideal for high-throughput clinical research studies in anatomical pathology or biomarker research.

Up to 50 true square pixels / second for faster and better images Bruker’s new scanning 10 kHz smart-

beam™ - 3D laser technology provides highest throughput and better pixel-to-pixel reproducibility The 5 µm laser focus allows for square

imaging pixel with almost complete tissue coverage and no pixel-to-pixel interference rapifleX includes a novel self-aligning MALDI

ion source for maximum uptime

Proteins in sagittal rat brain section measured at 30 µm pixel size, ~150000 pixel.

MALDI-TOF/TOF

MALDI-TOF/TOF

The world’s most advanced MALDI-TOF/TOF ...

ultrafleXtreme™

The ultrafleXtreme is built to deliver the highest levels of performance in sensitivity, resolution, and mass accuracy for a MALDI instrument. It is the world’s most advanced MALDI-TOF/TOF with true 2 kHz speed in TOF mode and 1 kHz speed in TOF/TOF mode.

As an extremely flexible mass spectro-meter with the full power of the patented smartbeam™-II laser technology, ultrafleX-treme is especially effective in proteomics, disulfide detection, glycoprotein characteriza-tion and can perform top-down sequencing of intact proteins in less than one minute. It is used in a broad variety of complementary clinical research and applied proteomic applications.

Other cutting-edge MALDI technology en-hancements, such as PAN™ resolution for broad mass range measurements and LIFT™ technology to enhance sensitivity, make the ultrafleXtreme ideal for use in top-down or bottom-up protein analysis utilizing gel or LC-based workflows.

Outstanding in both quantitative and qualita-tive applications, the ultrafleXtreme represents the ultimate in MALDI-TOF/TOF instrument design and performance capabilities.

Key Applications

Detailed protein characterization with LC-MALDI Top-down sequencing in 1 minute Disulfide detection Glycoprotein characterization Intact protein mass measurement

... quick and reliable results ...

Key Applications

MALDI molecular imaging of proteins Intact protein characterization MALDI PharmaPulse: Label-free

high throughput screening (HTS) Protein identification and characterization Polymer analysis

autoflex speed™

The autoflex speed is a workhorse MALDI-TOF mass spectrometer, delivering high sensitivity detection with sufficient speed for many MALDI applications, including protein/peptide characterization, polymer analysis, tissue imaging, glycan analysis, high throughput screening (HTS) and research in microbiology. It incorporates the proprietary smartbeam™-II technology with 2 kHz speed in TOF mode for unrivalled speed, sensitivity, and resolution in an instrument of this class.

This powerful autoflex speed is easy to master and features a number of hardware options:

Linear-only mode High resolution reflectron mode LIFT™ – the latest TOF/TOF technology

to enable the use of various MS/MS techniques, including LID and high-energy CID Fully automated plate management for true

label-free HTS

Equipped with a number of specially designed software packages, the autoflex speed becomes a customized instrument for key applications, including molecular imaging or protein sequencing and analysis and represents the fastest MS system for bio-chemical screening with less than 1 second per sample.

MALDI

... a workhorse ... generating sensitive results with recognizable speed.

Fast and reliable identification of various bacterial species with MALDI-TOF mass spectra profiling using MALDI Biotyper, identified by their individual pro-teomic fingerprint.

Identification of Bacteria Using a Bruker MALDI Biotyper

microflex™ LT/SH

The microflex LT/SH is the affordable entry-level member of the FLEX line of mass spectrometers that provide quick and reliable results from the smallest sample amounts. The microflex LT/SH is a true benchtop solution taking up less than 1 meter/ 40'' of counter space to provide flexibility in meeting laboratory needs.

It is easy to use with intuitive operations that are ideal for non-expert users and busy multi-instrument labs.

microflex delivers value and performance of MALDI mass spectrometry to any laboratory, including those where mass spectrometry was thought to be out of reach.

A key example of this can be found in many microbiology laboratories where the introduc-tion of the MALDI Biotyper system solution with microflex LT/SH has revolutionized the identification of microorganisms.

Gridless, self- cleaning ion source Excellent sensitivity in positive ion mode CompassTM software

for intuitive operation

MALDI Biotyper®

The MALDI Biotyper (MBT) is the market-leading system for microbial identification based on proteomic fingerprinting by high-throughput MALDI-TOF mass spectro-metry, where unique species-specific patterns are automatically compared with reference spectra in the MALDI Biotyper library.

In many laboratories, the MALDI Biotyper has, in recent years, replaced classical biochemical testing for bacterial identification as a result of the system’s accuracy, speed, extensive species coverage, ease of use and cost effec-tiveness. Classical biochemical techniques, detecting different metabolic properties of microorganisms, can take many hours or even days to process, and they often lack sufficient specificity.

Applications for the various MALDI Biotyper solutions include clinical routine microbial identification, environmental and pharmaceu-tical analysis, taxonomical research, food and consumer product safety and quality control,

as well as marine microbiology. With more than 1,800 customer systems installed, the MBT platform has become the accepted lab-oratory-standard for next-generation microbial identification and further emerging high-value functional assays.

The products of the MALDI Biotyper family are available in a research-use-only (RUO) version, as the U.S. FDA-cleared MALDI Biotyper CA System, or in an IVD-CE version meeting the requirements of EU directive EC/98/79. The MALDI Biotyper also has medical device registrations in numerous other countries.

The application range of this unique system is now further expanded by the new MBT STAR (Selective Testing of Antibiotic Resistance) product line enabling high-value antimicrobial resistance tests (RUO) in translational research.

Changing Microbiology

MALDI Biotyper

MALDI Biotyper ® smart

MALDI Biotyper (MBT) is Bruker’s pioneering solution for rapid and accurate identification of microorganisms using mass spectrometry.

As the market-leading solution for mass spectrometry based microbial identification, the MALDI Biotyper is used in clinical microbiology, environmental and pharma-ceutical analysis, taxonomical research, food and consumer product processing and quality control, and veterinary microbiology.

The speed, convenience, and cost-efficiency of the MALDI Biotyper system means that some laboratories are tasked with producing ever increasing numbers of microbial identifications.

Novel workflows – such as rapid microbial identification from positive blood cultures using Bruker‘s MALDI Sepsityper® Kit or Selective Testing of Antibiotic Resistance (MBT STAR-BL) – are further expanding the MALDI Biotyper’s range of applications.

First microbiology mass spectrometry system with smartbeam™ lifetime* laser technology

Thanks to Bruker’s smartbeam solid-state laser technology, the MALDI Biotyper smart is equipped to meet the challenges of even higher throughput and even faster turnaround times, both now and in the future.

The patented smartbeam laser combines the longer (at least one order of magnitude) laser lifetime of solid-state lasers with the unmatched MALDI performance of nitrogen lasers. Rapid sampling is provided by the smartbeam laser’s repetition rates of up to 200 Hz, more than 3 times faster than conventional nitrogen lasers used for microbial identification.

*lifetime: 500 million laser shots or seven years – whichever comes first.

Systems for Optimal MALDI Sample Preparation

Traceability, Quality and Confidence in a Standardized and Automated Workflow

For microbial MALDI target preparation

MALDI Biotyper Galaxy®

The MALDI Biotyper Galaxy automated MALDI target preparation system frees laboratory personnel from routine work while ensuring the highest preparation quality in a paperless workflow.

Full traceability is given by seamless inte-gration with the MALDI Biotyper system. On-board barcode reading ensures that MALDI target plates are matched to their corresponding projects so that every sample is correctly prepared.

Latest spotting technology guarantees that each sample spot is coated with the identical volume of MALDI matrix. Quality control of the entire preparation process using integrated optoelectronic sensor technology ensures that each sample spot is optimally prepared for subsequent MALDI-TOF mass spectrometry analysis.

ImagePrep™

"Push-button" matrix application

Comprehensive and reliable tissue sample preparation for MALDI Imaging

The ImagePrep is a matrix desposition device for MALDI Imaging in biomarker discovery, drug imaging and pathology research. The device provides highly reproducible sample preparations for MALDI Imaging in a fully automated, push-button process.

In the ImagePrep station, a matrix aerosol is created by vibrational vaporization under controlled conditions that is gently deposited onto tissue sections.

An optical sensor monitors the light scattered from matrix crystals to control all relevant preparation parameters in real-time.

Bruker‘s TOF and quadrupole TOF mass spectrometers feature some of the very latest developments in TOF technology to provide maximum confidence for accurate mass molecular formula determination.

Capable of delivering hyper-accurate results, Bruker‘s TOF platforms combine numerous hardware innovations with unique software packages that deliver industry leading sensi-tivity, five orders of magnitude dynamic range, sub-ppm mass accuracy and up to 80,000 resolution with no compromise in sensitivity for the analysis of small molecules and many types of biomolecules.

ESI-TOF

A high-performance hybrid ...

maXis™ II/ETD

Full Sensitivity Resolution – Extreme Performance

The maXis II with Full Sensitivity Resolution (FSR) continues to advance the performance level and capabilities of this revolutionary series of instruments.

With significant enhancements in mass accuracy and resolution, and unparalleled sensitivity and speed, the maXis II offers the confidence to measure, identify and characterize small molecules, proteins, and intact large molecules such as antibodies and subunits with unprecedented levels of certainty. Electron-Transfer Dissociation (ETD) capabilities is an option.

Key Applications

Middle-up antibody and intact protein MW analysis Native mass spectrometry ETD top-down and

middle-down sequencing

ESI-TOF

impact™ II

The new impact II is one of the latest inno-vations in Bruker’s unique UHR-Q-TOF (Ultra-High Resolution Qq-Time-of-Flight) mass spectrometry product line with indus-try-leading >50,000 Full-Sensitivity Resolution (FSR). It opens up enhanced analytical performance levels for all applications where trace analysis from complex, high-background matrices is a challenge, such as omics research, identification of impurities, or residue screening.

The impact II sets a new technology standard where industry leading performance speci-fications are all simultaneously available in a single acquisition at full sensitivity.

Five orders of magnitude dynamic range achieved at UHPLC speeds from 50 GBit/sec sampling technology – definitive trace analysis from complex, high-background matrices CaptiveSpray nanoBooster™ with enhanced

peptide sensitivity matching for the best shot-gun proteomics identifications Instant Expertise: Intelligent self-optimizing

MS⁄MS routines for expert-caliber results even from first-time users One shot plug & play acquisition with triple-

quad standard sensitivity ensuring qualita - tive and quantitative results in one LC run with the fastest time-to-success

Key Applications

Untargeted discovery protein identification and quantitation Targeted protein quantitation Untargeted and targeted metabolomics Proteoform profiling Structural protein characterization Structural elucidation of glycopeptides

... sets the standard in bench-top ultra-high resolution tandem mass spectrometry.

compact™

The power of technology demanded for research applications is now available in a compact, robust, and economic benchtop system.

The new Bruker compact Q-TOF features:

Research-grade technology applied to every routine analytical task 50 GBit/sec sampling technology maintain-

ing full specification resolution even during ultrafast chromatography Increased dynamic range for definitive trace

analysis from complex, high-background matrices Low picogram sensitivity to rival the best

triple-quadrupole sensitivity while delivering full scan, precise, accurate mass data Superior 1 ppm mass accuracy ensured by

automated calibration

In combination with the Bruker FUSION-SVsolution, fully automatic structure verificationsynergizing NMR and MS data into one result becomes reality.

ESI-TOF

FTMS

Key Applications

High-end proteomics studies (top-down and bottom-up workflows) Molecular imaging of tissue

(distribution of drugs, metabolites, and biomarkers) Petroleum product analysis Complex environmental sample analysis Metabolomics research

FTMS

solariX™ XR

The easy-to-use solariX XR bundles together a wide range of technological advances to provide unparalleled analytical power in a robust, low-maintenance package. With the newly developed ParaCell™ as its core tech-nology, the solariX XR breaks the conventional barriers of mass spectrometry by providing greater than 10 million resolving power in a single scan. For the first time ever, this un-rivaled power allows for easy interrogation of isotopic fine structures across the mass range of interest, enabling next-generation workflows for a wide range of applications.

The ion funnel-based dual source instantly switches from API (ESI, APCI, APPI, etc.) to MALDI within the automated software environment with just a click of the mouse. This significantly streamlines data acquisition for all types of analyses from tissue imaging and complex mixtures to large proteins for top-down studies.

Advanced ParaCell technology and AMP™ processing provides greater than 10 million resolving power in a single mass spectrum and greater than about 300,000 resolving power in a one-second duty cycle eXtreme Resolution allows the user to

routinely view the isotopic fine structure to gain powerful insight and unlock the secrets of this previously hidden realm Fast switchover between MALDI and API

ionization in an always available, software- selectable environment Industry-leading flexibility for fragmentation

with included Electron Capture Dissocia- tion (ECD), quadrupole selected collisional activation (QCAD), optional Electron Transfer Dissociation (ETD), and Bruker’s Top-Down Sequencing (TDS™) 1 kHz smartbeam™ II laser for rapid tissue

imaging ( >90 pixels/minute) Fast polarity switching at high mass

accuracy (>4Hz) Powerful CASI™ technology for fast enrich-

ment of low abundant species 7T advanced low-maintenance refrigerated

magnet

Key Applications

General chemistry LC-MSn

Structural confirmation using MSn capabilities Screening research applications with

fast polarity switching Quality control, synthesis control Analysis of solid samples by

DirectProbeTM

Metabolite identification and profiling

A solid, robust, high-value platform ...

Fully automated research-based screening for toxins/drugs based on MS/MS library search. Push-button solution in an open-access environment.

Automated Screening Example

LC-MSn

The amaZon Ion Trap Series

amaZon SL™

The amaZon SL, Bruker’s entry-level ion trap, increases productivity for routine analyses in industrial applications and research. A solid, robust, high-value platform for fast LC-MSn applications, the amaZonSL makes high-quality and high-confidence chemical analysis available to any lab.

Its rugged ion source is designed for reliable 24/7 operation, even in an open-access envi-ronment. The amaZon SL comes equipped with the SmartLine software suite for quick and easy access to analytical workflows that help generate reliable results.

LC-MSn

Key Applications

Proteomics Metabolomics Compound screening and identification Detailed chemical analysis

amaZon™ speed

The amaZon speed, equipped with the latest high-sensitivity dual ion funnel technology and ultrafast scanning capabilities, sets new analytical standards for small molecule and screening applications. It’s an excellent choice for the analysis of complex samples when more in-depth and detailed analysis of molecular structure is needed. The amaZon speed offers dramatically enhanced MS/MS speed, sensitivity, and mass resolution. Supported by spectral MSn libraries, the amaZon speed is the ultimate mass spectrom-eter for MS/MS-based compound screening.

Increased MS/MS duty cycle for more productive data acquisition Best-in-class mass accuracy Leading dual ion funnel technology for

unparalleled sensitivity Zero Delay Alternating™ for polarity

switching with a minimum of 20 Hz MS acquisition speed New SMART isolation and fragmentation Unrivaled scan speed Support of fastest UPLC applications at a

maximum duty cycle

amaZon™ speed ETD

The amaZon speed ETD is the latest gen-eration ion trap instrument for proteomics applications and in-depth analysis of post- translational modifications. It delivers out-standing glycopeptide detection and charac-terization capacities with the combined use of the CaptiveSpray nanobooster, ETD,MSn, and glycoquest capacities. Incorporating ETD and PTR molecular fragmentation technologies, the amaZon speed ETD provides extremely valuable information about the location and nature of various PTMs, as well as useful de novo sequencing power for full coverage of the protein N- and C-terminal sequence.

A workhorse for delivering routine bottom-up proteomics results with extreme sensitivity Top down sequencing for biomarker

identification and protein characterization Leading dual ion funnel technology for

unparalleled sensitivity Outstanding ETD/PTR applications for full

PTM analysis Unrivalled scan speed and resolution of up

to 8+ charged peptides

... highest-performance LC-MS/MS ...

Key Applications

Forensic toxicology Drugs of abuse research Clinical research

Toxtyper™

The Toxtyper was developed to meet the needs of clinical research and forensic toxicology labs. It incorporates the amaZon speed ion trap to deliver a robust and automated research-based screening solution for identifying potential toxicants.

The Toxtyper provides a combination of the highest-performance LC-MS/MS and easy-to-use unknown identification with the greatest transferability of results from lab to lab. Patented SmartFrag™ technology removes variation and the need for complicated MS/MS tuning.

The wizard-driven Compass OpenAccess software delivers unsurpassed levels of acces-sibility, usability and automation in turnkey analytical environments. Toxtyper acquires data and processes it behind the scenes, whilst also offering the analyst the option of remote web based access to the system.

Unique and comprehensive library of more than 900 compounds based on retention time, MS, MS2, and MS3 ion trap spectra Ready-to-go screening methods Fast results within an 11-minute duty cycle Intuitive sample management and fully

automated reporting

LC-MSn

Ion Sources

APCI

DIP Option for APCI II

ESI

APPI

CaptiveSpray nanoBoosterGC-APCI II

Ion Sources

CaptiveSpray™ nanoBooster

The CaptiveSpray nanoBooster is the pro-teomics ion source that brings your MS to the next performance level. The operation is just as easy as performing electrospray. The nanoBooster enhances glycoanalysis and supercharging, and pushes up ID rates.

ionBooster

The ionBooster offers a 5 – 100x gain in sensitivity for many compounds of interest in the fields of environmental analysis, food testing, and research in the field of therapeutic drug monitoring.

APCI

Atmospheric Pressure Chemical Ionization is used in metabolomics, as well as for drug or pesticide screening for less polar molecules where ESI fails to deliver reasonable quantities of ions.

APPI

Atmospheric Pressure Photo Ionization is used for less polar or non-polar molecules that cannot be ionized in either ESI or APCI.

DIP

The DirectProbe add-on for the Bruker APCI II and APPI II ion sources allows for direct analysis of liquid and solid samples without tedious sample preparation.

GC-APCI II

The GC-APCI II source with unique flexible, heated transfer line, and calibrant delivery enables GC coupling to any Bruker TOF, QTOF, trap, or FTMS system originally designed for LC coupling.

Dynamic Source ConfigurationIn addition to the ESI sources, Bruker's life sciences MS systems support a wide range of source options from Bruker and from third-party vendors, all switchable within seconds.

... maximum information with minimal effort.

Software & ApplicationDirect Solutions

Compass & Bioinformatics

Bruker’s MS software solutions provide maximum information with minimal effort. Designed and delivered with the user and application in mind, these solutions are highly intuitive and extremely user-friendly.

Compass™: Bruker’s unified software environment for intuitive mass spectro- metric instrument control and data processing Compass OpenAccess™: Automated

walk-up LC/MS chemical formula generation Compass SecurityPack: Supporting work in

the regulated environment ProteinScape™: The bioinformatics platform

for protein characterization, identification and quantitation DisulfideDetect: Automated Disulfide

identification BioPharmaCompass™: Automated

biopharma workflows from analysis to printed reports

flexImaging™ and SCiLS Lab™: Compre- hensive and powerful MALDI Imaging MBT Compass™: Fast and easy microbial

identification MetaboliteTools™: Identification and

confirmation of metabolites ProfileAnalysis™: Comprehensive statisti-

cal evaluation of LC-MS data TargetAnalysis™: Unambiguous molecular

formula identification PolyTools™: Interpretation of MALDI

polymer spectra Compass PathwayScreener™: Biochemical

Pathway driven targeted metabolomics Bruker HMDB Metabolite Library™:

Accelerate Known Target Compound Identification Bruker FUSION-SV: Fully integrated

HRAM-MS and NMR data for unrivalled structure verification

Software, Applications

ToxScreener and PesticideScreener Solutions

Bruker ToxScreener™ and PesticideScreener™ accurate mass solutions are designed to enable comprehensive forensic toxicolog-ical and pesticide screening respectively, utilizing Bruker’s industry leading QTOF instrumentation.

Both screening solutions minimize method development time and are supplied with an application kit including UHPLC accessories and complete analysis protocols for the chro-matographic and mass spectrometric steps. At the heart of each of Bruker’s screener solutions is a high-quality, application-specific, accurate mass database enabling you to cross-reference and verify experimental observations with maximum confidence in the shortest possible time.

MALDI PharmaPulse – High Throughput Screening (HTS)

MALDI PharmaPulse is a complete mass spectrometry based screening solution designed to accelerate all phases of drug discovery. The system offers the advantage of true label-free detection of native substrates and products in functional bio-chemical assays.

Based on Bruker’s market leading FLEX series, the ultrafast MALDI-TOF system delivers analytical results in less than 1 second per sample making it uniquely suited for High Throughput Screening (HTS) applications.

Applications – Software

Bruker offers dedicated software packages and solutions for various application areas:

Life Science Research and Clinical Research Applications Solutions Discovery and targeted proteomics Protein characterization and profiling MALDI molecular imaging Identification of microorganisms LC-MS-based metabolomics Metabolite profiling with LC-MS NMR Biopharmaceutical analysis

Pharmaceutical and Applied Analytical Application Solutions Identification of unknowns Pesticide, toxin, and pollutant screening Drug metabolite identification Open access chemistry support Petroleomics Polymer analysis

1536-well plate readin less than 25 minutes.

Key Applications

Food testing Environmental analysis Forensic toxicology Pharmacokinetics Clinical Research

LC-MS/MS

EVOQ LC-TQ™

The EVOQ triple quadrupole for liquid chroma-tography (LC-TQ) was designed for a singular purpose—to reliably quantify thousands of real samples in the fastest sample-to-report time possible. Available in EVOQ Elite, EVOQ Elite ER, and EVOQ Qube™ models, this latest LC-TQ series brings research technology to the commercial lab.

The EVOQ delivers exceptional sensitivity, precision, accuracy, and a wide dynamic range for multiple reaction monitoring (MRM) assays. Innovations in software and atmo-spheric pressure ionization (API) technology make it a game-changer for routine high-sensitivity, quantitative analysis.

The EVOQ LC-MS/MS is a Laboratory Equipment magazine Readers’ Choice award winner. Here are some of the reasons why:

Easily obtain ultrahigh sensitivity for small molecules and biomolecules as a result of the innovative interlaced quadrupole dual ion funnel Efficiently analyze thermally labile molecules

at high flow rates with the novel vacuum- insulated heated electrospray probe Save time using exception-based data-

review software that makes it easier to highlight chromatograms that do not meet preset method criteria

LC-MS/MS

GC-MS/MS

GC-MS/MS

EVOQ GC-TQ™

The EVOQ GC-TQ, the chromatographer’s choice of triple quadrupole mass detector, meets the most stringent needs for analytical performance and productivity. The bench-space-saving EVOQ GC-TQ delivers unrivaled performance and reliability in the smallest footprint. The lens-free elliptical ion-path design delivers ultrahigh sensitivity and greatly reduces neutral or chemical noise. Gain superior sensitivity and robustness from ion optics and fast and easy method development for multi-component quantitation using Compound Based Scanning (CBS) with the factory installed MRM library.

Simple Tuning: Lens-free ion path for higher stability and sensitivity More Sensitivity: Active-focusing q0 uses

helium molecules to increase ion transmission Higher S/N: Elliptical ion-path design that

results in reduced neutral or chemical noise Easy MRM Method Set Up: Factory supplied

MRM information auto-fills acquisition and data handling tables simultaneously Unrivaled NCI Performance: Negative ions

are detected directly for enhanced sensitivity Eliminate reinjections: Patented Extended

Dynamic Range (EDR) detector prevents saturation at higher sample concentrations

Industry’s first triple quadrupole software that lets you think like a chromatographer.

Compound-based screening

Industry‘s first triple quadrupole software

Business partner – our service program gives you:

Peace of mind. You can focus on important tasks and rely on our efficiency and expertise gained over five decades Higher instrument uptime. Increased

instrument reliability, priority response time, and reduced administrative work Factory-trained support Predictable service budgets Reduced paperwork

Bruker Advanced Customer Services

OneSuccess

A comprehensive support solution designed for your success. OneSuccess is a win-win program which includes Support, Service and Upgrades, Consumables and Spares, as well as Education and Training, and customer-specific updates on product developments

A flexible solution through a range of service plans:

Extended Warranty Priority response time, unlimited service visits, spare parts Complete

Priority response time, unlimited service visits, spare parts and PM Advanced

Priority response time, unlimited service visits and PM Enhanced

Priority response time, spare parts and PM Essential

Annual planned maintenance, scientific support, remote diagnostic À la carte

Custom combination of any available service

All service plans can be tailored to your needs and budget

Our OneSuccess program includes a combination of the following modules:

Reliability Selection of services to keep your instrument up and running at peak performance Performance

Selection of additional features to add performance for new requirements Expertise

Selection of training courses to increase your lab productivity Consumables

Selection of Bruker-approved consumables to guarantee optimal performance

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Bruker Daltonik GmbH

Bremen · Germany

Phone +49 (0)421-2205-0 Fax +49 (0)421-2205-103

Bruker Daltonics Inc.

Billerica, MA · USA

Phone +1 (978) 663-3660 Fax +1 (978) 667-5993

ms.sales.bdal@bruker.com - www.bruker.com

For many decades, Bruker has been committed to providing scientists with the very best in innovative mass spectrometry and analytical systems solutions. Bruker’s systems are expertly designed for performance, utility, and feature a number of unique capabilities and technologies to enhance data quality and facilitate data analysis. Bruker’s systems are often the most powerful and the highest performance instruments in their class. Recent advances in Bruker’s product lines make this analytical power more accessible than ever to both new and expert users.

Bruker offers a range of stand-alone and integrated mass spectrometry and analytical system solutions that deliver a variety of information levels and are ideal for small molecule, protein and peptide, or polymer analysis.

Bruker’s product portfolio includes the following:

MALDI TOF MS ESI-(Q)TOF FTMS ESI Ion Trap GC-MS/MS LC-MS/MS Ion Sources Software for instrument control and data analysis Application Area Specific Solutions

Ongoing support

Bruker’s Sales, Service, and Applications team will assist you in assembling your individual solution package, allowing you to go from sample straight to results. We will not just meet your requirements and expectations, we will exceed them! Ongoing support is available for the following:

Service System integration Applications support Training

For research use only. Not for use in diagnostic procedures.

High Performance, Easy-to-Use, Expertly Supported