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FORM-1

FOR

PROPOSED BULK DRUGS & BULK DRUG

INTERMEDIATES MANUFACTURING UNIT

OF

M/s. KRISHNA CHEMTECH

Plot No. 2213, GIDC Estate,

Panoli-394116, Dist: Bharuch, Gujarat

Prepared by:

Aqua-Air Environmental Engineers Pvt. Ltd.

(Pollution Control Consultants & Engineers)

Reg. Office: 403, Centre Point, Nr. Kadiwala School, Ring Road,

Surat – 395 002, Gujarat, India Fax: +91 261 2707273 / 3987273 Tel: + 91 261 3048586 / 2460854 / 2461241

E-mail: [email protected] Visit us at: www.aqua-air.co.in

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APPENDIX I

(See paragraph - 6)

FORM 1

Sr.

No.

Item Details

1. Name of the project/s M/s. Krishna Chemtech

2. S. No. in the schedule 5 (f)

3. Proposed capacity/area/length/tonnage

to be handled/command area/lease

area/number of wells to be drilled

Proposed area = 1,500 sq. mt.

4. New/Expansion/Modernization New

5. Existing Capacity/Area etc. For detail Please refer Annexure – I

6. Category of Project i.e. ‘A’ or ‘B’ ‘A’

7. Does it attract the general condition? If

yes, please specify.

Yes. Located within 5 km of critically polluted

area (Ankleshwar).

8. Does it attract the specific condition? If

yes, please specify.

No

9. Location

Plot/Survey/Khasra No. Plot No. 2213

Village Panoli

Tehsil Ankleshwar

District Bharuch

State Gujarat

10. Nearest railway station/airport along

with distance in kms.

Railway Station: Ankleshwar (4.5 km)

Airport: Surat (60 km)

11. Nearest Town, city, District Headquarters

along with distance in kms.

Panoli Village (3.5 km)

Bharuch (16.9 km), Ankleshwar (4.0 km)

12. Village Panchayats, Zilla Parishad,

Municipal Corporation, local body

(complete postal address with telephone

nos. to be given)

Notified Area Authority, Panoli

13. Name of the applicant M/s. Krishna Chemtech

14. Registered Address Plot No. 2213, GIDC Estate, Panoli-394116,

Dist: Bharuch, Gujarat

15. Address for correspondence: Plot No. 2213, GIDC Estate, Panoli-394116,

Dist: Bharuch, Gujarat

Name Mr. Arvind Gevariya

Designation (Owner/Partner/CEO) Proprietor

Address 205, Shyamal Building, Kohinoor Road, Mini

Bazar, Varachha Road, Surat-395006, Gujarat

3

Pin Code 395006

E-mail [email protected]

Telephone No. --

Fax No. --

Mobile No. +9198796 55109

16. Details of Alternative Sites examined, if

any.

Location of these sites should be shown

on a topo sheet.

NA

17. Interlinked Projects No

18. Whether separate application of

interlinked project has been submitted?

No

19. If yes, date of submission No

20. If no, reason No

21. Whether the proposal involves

approval/clearance under: if yes, details

of the same and their status to be given.

(a) The Forest (Conservation) Act, 1980?

(b) The Wildlife (Protection) Act, 1972?

(c) The C.R.Z. Notification, 1991?

No

22. Whether there is any Government

Order/Policy relevant/relating to the

site?

No

23. Forest land involved (hectares) No

24. Whether there is any litigation pending

against the project and/or land in which

the project is propose to be set up?

(a) Name of the Court

(b) Case No.

(c) Orders/directions of the Court, if any

and its relevance with the proposed

project.

No

• Capacity corresponding to sectoral activity (such as production capacity for

manufacturing, mining lease area and production capacity for mineral production, area for mineral exploration, length for linear transport infrastructure, generation capacity for power generation etc.,)

4

(II) Activity

1. Construction, operation or decommissioning of the Project involving actions, which will cause physical changes in the locality (topography, land use, changes in water bodies, etc.)

Sr.

No.

Information/Checklist confirmation Yes/No Details thereof with approximate

quantities frates, wherever possible)

with source of information data

1.1 Permanent or temporary change in land use, land cover or topography including increase intensity of land use (with respect to local land use plan)

No Proposed project activity is within the Panoli GIDC Industrial Estate.

1.2 Clearance of existing land, vegetation

and Buildings?

Yes Minor site clearance activities shall be carried out to clear shrubs and weed.

1.3 Creation of new land uses?

No The project site is located on level ground, which does not require any major land filling for area grading work.

1.4 Pre-construction investigations e.g. bore Houses, soil testing?

No

1.5 Construction works?

Yes Please refer Annexure – II.

1.6 Demolition works? No There will be not any demolition work at the site.

1.7 Temporary sites used for construction

works

or housing of construction workers?

No

1.8 Above ground buildings, structures or

earthworks including linear structures,

cut

and fill or excavations

Yes Please refer Annexure – II.

1.9 Underground works mining or

tunneling?

No

1.10 Reclamation works?

No

1.11 Dredging?

No

1.12 Off shore structures?

No

1.13 Production and manufacturing

processes?

Yes Please refer Annexure –III.

5

1.14 Facilities for storage of goods or

materials?

Yes For Proposed Project Activity, raw material & finished products storage area will be developed.

1.15 Facilities for treatment or disposal of

solid waste or liquid effluents?

Yes For Facilities for treatment or disposal of liquid effluents is referred as Annexure-V. For Hazardous waste detail please refer Annexure – VI.

1.16 Facilities for long term housing of

operational workers?

No

1.17 New road, rail or sea traffic during

Construction or operation?

No

1.18 New road, rail, air waterborne or other

transport infrastructure including new or

altered routes and stations, ports,

airports etc?

No

1.19 Closure or diversion of existing transport

routes or infrastructure leading to

changes in

Traffic movements?

No

1.20 New or diverted transmission lines or

Pipelines?

No

1.21 Impoundment, damming, culverting,

realignment or other changes to the

hydrology of watercourses or aquifers?

No

1.22 Stream crossings? No

1.23 Abstraction or transfers of water form

ground

or surface waters?

Yes Water requirement will be met through GIDC water supply.

1.24 Changes in water bodies or the land

surface

Affecting drainage or run-off?

No

1.25 Transport of personnel or materials for

construction, operation or

decommissioning?

Yes Transportation of personnel or raw material and products will be primarily by road only.

1.26 Long-term dismantling or

decommissioning or restoration works?

No

1.27 Ongoing activity during

decommissioning which could have an

impact on the environment?

No

1.28 Influx of people to an area either

temporarily or permanently?

No

1.29 Introduction of alien species? No

1.30 Loss of native species or genetic

diversity?

No

1.31 Any other actions? No

6

2. Use of Natural resources for construction or operation of the Project (such as land, water, materials or energy, especially any resources which are non-renewable or in short supply):

Sr.

No.

Information/checklist confirmation Yes/No Details thereof (with approximate

quantities /rates, wherever possible)


2.1 Land especially undeveloped or agricultural

land (ha)

No Proposed project activity will be within

GIDC Industrial Area, Panoli, Dist:

Bharuch.

2.2 Water (expected source & competing users)

unit: KLD

Yes Water Source: Panoli GIDC Water

Supply

For details please refer Annexure – IV.

2.3 Minerals (MT) No

2.4 Construction material - stone, aggregates,

and / soil (expected source - MT)

Yes Construction materials, like steel,

cement, crushed stones, sand, rubble,

etc. required for the project shall be

procured from the local market of the

region.

2.5 Forests and timber (source - MT) No.

2.6 Energy including electricity and fuels

(source, competing users) Unit: fuel (MT),

energy (MW)

Yes

FUEL:

Agrowaste = 5 MT/Day

Diesel = 5 Lit/Hr (Emergency case)

ENERGY:

250 KVA (DGVCL)

1 DG Set = 100 KVA (Emergency case)

2.7 Any other natural resources (use

appropriate standard units)

No

3. Use, storage, transport, handling or production of substances or materials, which could be harmful to human health or the environment or raise concerns about actual or perceived risks to human health.

Sr.

No.

Information/Checklist confirmation Yes/No Details there of (with approximate

quantities/rates, wherever possible)


3.1 Use of substances or materials, which are

hazardous (as per MSIHC rules) to human

health or the environment (flora, fauna,

and water supplies)

Yes Please refer Annexure –VIII.

3.2 Changes in occurrence of disease or affect

disease vectors (e.g. insect or water borne

diseases)

No

3.3 Affect the welfare of people e.g. by

changing living conditions?

No

7

3.4 Vulnerable groups of people who could be

affected by the project e.g. hospital

patients, children, the elderly etc.

No

3.5 Any other causes No

4. Production of solid wastes during construction or operation or decommissioning (MT/month)

Sr.

No.


quantities/rates, wherever

possible) with source of

information data

4.1 Spoil, overburden or mine wastes No

4.2 Municipal waste (domestic and or

commercial wastes)

No

4.3 Hazardous wastes (as per Hazardous Waste

Management Rules)

Yes Please refer Annexure – VI.

4.4 Other industrial process wastes Yes Please refer Annexure – VI.

4.5 Surplus product No

4.6 Sewage sludge or other sludge from

effluent treatment

No

4.7 Construction or demolition wastes No

4.8 Redundant machinery or equipment No

4.9 Contaminated soils or other materials No

4.10 Agricultural wastes No

4.11 Other solid wastes Yes

Please refer Annexure – VI.

5. Release of pollutants or any hazardous, toxic or noxious substances to air (Kg/hr)

Sr.

No.




5.1 Emissions from combustion of fossil fuels

from stationary or mobile sources

Yes Please refer Annexure – VII.

5.2 Emissions from production processes Yes Please refer Annexure – VII.

5.3 Emissions from materials handling storage

or transport

No

5.4 Emissions from construction activities

including plant and equipment

No

5.5 Dust or odours from handling of

materials including construction

materials, sewage and waste

No

8

5.6 Emissions from incineration of waste No

5.7 Emissions from burning of waste in open

air e.g. slash materials, construction

debris)

No

5.8 Emissions from any other sources Yes Please refer Annexure – VII.

6.Generation of Noise and Vibration, and Emissions of Light and Heat:

Sr.

No.



with source of information data with

source of information data

6.1 From operation of equipment e.g.

engines, ventilation plant, crushers

Yes The Noise level will be within the

prescribed limit. At noisy areas

adequate preventive & control

measures will be taken. No significant

noise, vibration or emission of light &

heat from the unit.

6.2 From industrial or similar processes Yes -Do-

6.3 From construction or demolition No

6.4 From blasting or piling No

6.5 From construction or operational traffic No

6.6 From lighting or cooling systems No

6.7 From any other sources No

7. Risks of contamination of land or water from releases of pollutants into the ground or into sewers, surface waters, groundwater, coastal waters or the sea:

Sr.

No.




7.1 From handling, storage, use or spillage of

hazardous materials

Yes Please refer Annexure – VIII.

7.2 From discharge of sewage or other

effluents to water or the land (expected

mode and place of discharge)

Yes For details please refer Annexure – V.

7.3 By deposition of pollutants emitted to air

into the and or into water

No

7.4 From any other sources No

9

7.5 Is there a risk of long term build up of

pollutants in the environment from these

sources?

No

8. Risk of accidents during construction or operation of the Project, which could affect human health or the environment

S.No. Information/Checklist confirmation Yes/No Details there of (with approximate

quantities/rates,wherever possible)


8.1 From explosions, spillages, fires etc from

storage, handling, use or production of

hazardous substances

Yes Please refer Annexure – VIII.

8.2 From any other causes No

8.3 Could the project be affected by natural

disasters causing environmental damage

(e.g. floods, earthquakes, landslides,

cloudburst etc)?

No

9. Factors which should be considered (such as consequential development) which could lead to environmental effects or the potential for cumulative impacts with other existing or planned activities in the locality

Sr. No.

Information/Checklist confirmation

Yes/No

Details there of (with approximate

quantities / rates, wherever

possible) with source of

information data

9.1 Lead to development of supporting.

utilities, ancillary development or

development stimulated by the project

which could have impact on the

environment e.g.

• Supporting infrastructure (roads,

power supply, waste or waste water

treatment, etc.) • housing development • extractive industry • supply industry • other

Yes Please refer Annexure – IX.

9.2 Lead to after-use of the site, which

could have an impact on the

environment

No

9.3 Set a precedent for later developments No

9.4 Have cumulative effects due to

proximity to other existing or planned

projects with similar effects

No

10

(II) Environmental Sensitivity

Sr.

No.

Areas Name/

Identity

Aerial distance (within 15 km.)

Proposed project location boundary

1 Areas protected under international

conventions, national or local legislation for

their ecological, landscape, cultural or other

related value

No Proposed project site is within the GIDC

Industrial Estate, Panoli.

2 Areas which important for are or sensitive

Ecol logical reasons - Wetlands,

watercourses or other water bodies, coastal

zone, biospheres, mountains, forests

No

3 Area used by protected, important or

sensitive.Species of flora or fauna for

breeding, nesting, foraging, resting, over

wintering, migration

No No protected area or sensitive species

within 15 km from the proposed project

boundary.

4 Inland, coastal, marine or underground

waters

No River Narmada – 13.7 kms

5 State, National boundaries No N.A.

6 Routes or facilities used by the public for

access to recreation or other tourist, pilgrim

areas

Yes Public transportation

7 Defense installations Yes Ankleshwar

8 Densely populated or built-up area Yes Panoli village 3.5 km and Ankleshwar City

around 4.0 km from the proposed project

site.

9 Area occupied by sensitive man-made land

uses Hospitals, schools, places of worship,

community facilities)

No

10 Areas containing important, high quality or

scarce resources (ground water resources,

surface resources, forestry, agriculture,

fisheries, tourism, minerals)

No

11 Areas already subjected to pollution

environmental damage. (those where

existing legal environmental standards are

exceeded)or

Yes Ankleshwar

12 Areas susceptible to natural hazard which

could cause the project to present

environmental problems (earthquake ,

subsidence ,landslides, flooding erosion, or

extreme or adverse climatic conditions)

No NA

IV). Proposed Terms of Reference for EIA studies:Please refer Annexure - X

11

I hereby given undertaking that, the data and information given in the application and

enclosures are true to the best of my knowledge and belief and I am aware that if any

part of the data and information submitted is found to be false or misleading at any

stage the project will be rejected and clearance give, if any to the project will be revoked

at our risk and cost.

Date: 22/6/2017

Place: GIDC Panoli

Signature of applicant

NOTE:

1. The projects involving clearance under Coastal Regulation Zone Notification, 1991 shall

submit with the application a C.R.Z. map duly demarcated by one of the authorized agencies,

showing the project activities, w.r.t. C.R.Z. (at the stage of TOR) and the recommendations of

the State Coastal Zone Management Authority (at the stage of EC). Simultaneous action shall

also be taken to obtain the requisite clearance under the provisions of the C.R.Z. Notification,

1991 for the activities to be located in the CRZ.

2. The projects to be located within 10 km of the National Parks, Sanctuaries, Biosphere

Reserves, Migratory Corridors of Wild Animals, the project proponent shall submit the map

duly authenticated by Chief Wildlife Warden showing these features vis-à-vis the project

location and the recommendations or comments of the Chief Wildlife Warden thereon (at the

stage of EC).

3. All correspondence with the Ministry of Environment & Forests including submission of

application for TOR/Environmental Clearance, subsequent clarifications, as may be required

from time to time, participation in the EAC Meeting on behalf of the project proponent shall

be made by the authorized signatory only. The authorized signatory should also submit a

document in support of his claim of being an authorized signatory for the specific project.

12

LIST OF ANNEXURES

SR. NO. NAME OF ANNEXURE

I List of Products and Raw materials along with their Production Capacity

II Layout Map of the Plant

III Brief Manufacturing Process Description

IV Details of water consumption & waste water generation

V Details of Effluent Treatment Scheme

VI Details of Hazardous Waste Generation and Disposal

VII Details of Stacks and Vents, Fuel & Energy Requirements

VIII Details of Hazardous Chemicals Storage & Handling

IX Socio-economic Impacts

X Proposed Terms of Reference

13

ANNEXURE - I

____________________________________________________________________________

LIST OF PRODUCTS ALONG WITH THEIR PRODUCTION CAPACITY WITH RAW MATERIALS

SR.

NO. PROPOSED PRODUCTS CAS NO.

PRODUCTION

CAPACITY

(MT/MONTH)

1 1,4-di bromo Butane , 99% 110-52-1

50

2 1-(4-fluoro phenyle piperazine) , 99% 2252-63-3

3 1-benzylepiperazine 2759-28-6

4 N,N-Bis 2-chloro ethyle amine 821-48-7

5 Cyclo propyl methyl ketone 765-43-5

6 Chlorozoxanone 95-25-0

7 Aceclofenac 89796-99-6

8 Fluconazole 86386-73-4

9 Niclosamide 50-65-7

10 1-(4- Methoxyphenyl)-1-(4-nitrophenyl)

piperazine 74852-61-2

11 1-(4-Methoxyphenyl) piperazine

38212-30-5

12 6-Methyl pyridine-3 yl-2,4-Methylsulfonyl

phenyl Etanone (Ketosulfone)

221615-75-4

13 4 Bromo methyl 2 Cyano biphenyl (Bromo

OTBN) 114772-54-2

Total 50

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LIST OF RAW MATERIAL

Sr.

No. Proposed Product Raw material Capacity(MT/MONTH)

[1] 1,4-Di bromo Butane,

99%

1,4-Butanediol 20.87

Hydrobromic acid (48%) 78.06

Toluene 50.00

[2] 1-(4-fluoro phenyle

piperazine) ,99%

4-Fluoroaniline 30.82

Bis(2-

Chloroethylamine)hydrochloride 49.51

Isopropyl alcohol 57.50

Potassium carbonate 200.00

[3] 1-benzylepiperazine Benzyl chloride 35.91

Piperazine 24.43

Toluene 50.00

Sodium hydroxide 11.34

[4] N,N-Bis 2-chloro ethyle

amine Diethanol amine 30

Thionyl chloride 34

Hydrochloric acid 11

Ammonium hydroxide 12.5

Toluene 200

[5] Cyclo propyl methyl

ketone 5-chloro-2-pentanone 83

Caustic Lye 85.5

[6] Chlorozoxanone 4-Chloro-2- Amino Phenol 47.5

Urea 47.5

Hydrochloric acid 102

Methanol 150

Activated Carbon 5.5

Sulphuric acid 5

Acetic acid 25

Sodium Hydrosulphite 2.5

15

[7] Aceclofenac Chloro Acetyl Chloride 27.5

Tertiary Butyl Alcohol 18

Dimethyl Aniline 32.5

Soda Ash 0.5

Caustic Lye 48% 22.5

Diclofenac Sodium 51.5

Formic Acid 35.5

Toluene 51.5

[8] Fluconazole 1,2,4-Trizole 26

Potassium Hydroxide 37.5

Tri Methyl Sulfonium Iodide 26

Di-floro acetophenone 58

Toluene 19.5

CP HCL 41.5

MDC 78

Citric acid 1.5

Carbon 3

Hyflow 1

[9] Niclosamide Xylene 142.86

Ortho Chloro Para Nitro Aniline 25.71

Thionyl Chloride 19.29

5-Nitro Salicyclic Acid 25.00

[10] 1-(4- Methoxyphenyl)-

1-(4-nitrophenyl)

piperazine

1-(4-Methyxy) Piperazine 32.82

Para Nitro Chlorobenzene 26.89

Potassium Carbonate 29.12

Dimethyl Formamide 38.33

Methanol 76.77

Acetone 77.68

Carbon 0.64

[11] 1-(4-Methoxyphenyl)

piperazine 4-Methoxy Aniline 57.47

Bis HCL-65% (As 100%) 102.59

16

Caustic Lye-48% 22.99

Sodium Carbonate 11.49

Sodium Hydrosulfite 1.44

Charcoal 0.57

HCL Solution-30% 20.69

[12] 6-Methyl pyridine-3 yl-

2,4-Methylsulfonyl

phenyl Etanone

(Ketosulfone)

4-Methyl Thiophenyl

Acetonitrile 32.00

Toluene 48.00

Sodium Methoxide 16.00

Methyl 6 Methyl Nicotinate 29.60

Methanol 30.00

Sodium Tangustate 0.60

Hydrogen Peroxide 32.00

Conc. Sulfuric Acid 1.00

[13] 4 Bromo methyl 2

Cyano biphenyl (Bromo

OTBN)

OTBN 45.45

Bromine 22.73

Methylene Dichloride 295.45

Hydrogen Peroxide (30%) 37.27

4-Bromo Methyl 2-

Cyanobiphenyl (Bromo OTBN) +

MDC

370.45

Ethyl Acetate 113.64

17

ANNEXURE - II

___________________________________________________________________________

LAYOUT OF MAP OF THE PLANT

18

1,4-ButanediolHydrobromic acid 1,4-Dibromobutane Water

H2O

Toluene

azeotropic

distillationHO OH HBr Br Br

ANNEXURE - III

___________________________________________________________________________

MANUFACTURING PROCESS, CHEMICAL REACTION & MASS BALANCE

[1] 1,4-Dibromobutane

MANUFACTURING PROCESS:

1,4-Butanediol is reacted with hydrobromic acid (48%) in the presence of an organic solvent

such as toluene at reflux temp and slowly remove water by azeotropically distillation

contineously till end of reaction. After completion of the raction distilled out solvent. The

final product 1,4-Dibromobutane is dried under vaccum to remove traces of moisture.

CHEMICAL REACTION:

MASS BALANCE:

Input Qty in kg

Output Qty in kg

1,4-Butanediol 8.347 1,4-Dibromobutane 20.000

Hydrobromic acid (48%) 31.223 Water (from acid & rxn.) 19.570

Solvent (Toluene) 20.000 Solvent (Toluene) 20.000

Total 59.570 Total 59.570

Note: Water generated during the process is as good as distilled water, because in the

process water is removed by azeotropic distillation.

19

4-Fluoroaniline Bis(2-chloroethyl Pottasium 1-(4-Fluorophenyl) piperazine Pottasium Water

amine)HCl carbonate Chloride

F NH2 NH.HCl

Cl

Cl

K2CO3

Isopropyl aclohol

80 deg C for 12 hrs.

N NHF KCl H2O

[2] 1-(4-Fluorophenyl) Piperazine


4-Fluoroaniline is reacted with Bis(2-chloroethylamine)HCl in the presence of an organic

solvent such as IPA & pottasium carbonate at 80 °C for 12 hours to give 1-(4-

Fluorphenyl)pierazine and pottasium chloride. Reaction continue till no more carbon dioxide

is evolved. The by product pottasium chloride is filltered off in pure form (while water

generated during reaction/neutralization will be retained by the wet cake of pottasium

chloride which will be lost during drying). Filltrate taken for distillation to remove the

solvent. The final1-(4-Fluorphenyl)piperazine, 99% is dried under vaccum to remove traces

of moisture/solvent.

CHEMICAL REACTION

MASS BALANCE:

Input Qty in kg

Output Qty in kg

4-Fluoroaniline 3.082 1-(4-Fluorophenyl) piperazine 5.000

Bis(2-Chloroethylamine) HCl 4.951 Potassium chloride 6.203

Potassium carbonate 5.750 Water 0.750

Isopropyl alcohol 20.000 Carbon dioxide 1.830

Isopropyl alcohol 20.000


Note: Water generated during the process will be retained by the wet cake of the

potassium chloride which will be lost during the drying.

20

Benzyl chloride Piperazine Sodium hydroxide 1-Benzylpiperazine Sodium chloride Water

CH2Cl HN NHNaOH CH2 N NH NaCl H2O

Toluene70 deg C

[3] 1-Benzylpiperazine


Benzylchloride is reacted with piperazine in the presence of an organic solvent such as

toluene at 70 °C for 8 hours to give 1-Benzylpiperazine hydrochloride. Hydrochloride salt of

the 1-Benzylpiperazine neutralise with sodium hydroxide to give 1-Benzylpiperazine, sodium

chloride and water. The by product sodium chloride is filltered off in pure form (while water

generated during neutralization will be retained by the wet cake of sodium chloride which

will be lost during drying). After filtration organic layer taken for distillation to remove the

solvent. The final product (1-Benzylpiperazine) is dried under vaccum to remove traces of

moisture.

CHEMICAL REACTIONS:

MASS BALANCE:

Input Qty in kg

Output Qty in kg

Benzyl chloride 7.182 1-Benzylpiperazine 10.000

Piperazine 4.886 Sodium chloride 3.314

Solvent (toluene) 10.000 Water 1.022

Sodium hydroxide 2.268 Solvent (toluene) 10.000


Note: Water generated during neutralization will be retained by the wet cake of sodium

chloride which will be lost during drying

21

[4] Bis (2-Chloroethyl) Amine Hydrochloride


Stage-1

Di ethanol amine undergoes chlorination with Thionyl chloride in presence of Toluene and

Methanol to give Bis (2-chloroethyl) amine Hydrochloride.

CHEMICAL REACTIONS:

MASS BALANCE:

22

[5] Cyclopropyl Methyl Ketone


5-chloro-2-pentanone is reacted with Caustic Lye (48%) in aqueous medium, cyclization

occurs to form crude CPMK which is further distilled out to get pure cyclopropyl methyl

ketone.

CHEMICAL REACTIONS:

H2O

C5H9ClO + NaOH ----------> C5H8O + NaCl + H2O

5-chloro-2- Caustic Lye cyclopropyl Sodium Water

pentanone methyl ketone Chloride

MASS BALANCE:

Input Qty in

Kg

Output

Qty in

Kg

5-chloro-2-pentanone 1.66 Cyclopropyl Methyl Ketone 1.0

Caustic Lye 48% 1.71 Water 1.63

Water 0.5 Sodium Chloride 1.20

Residue 0.04


23

[6] Chlorzoxazone

PROCESS DESCRIPTION:

Charge Urea, Acetic acid and Hydrochloric acid with 4-Chloro-2- Amino Phenol In the reactor

and heat up to 95 0C and maintain for 1 hr. Check TLC then centrifuge crude material at 30

0C, then wash with water till neutral pH.Add Charcoal and heat to reflux for 2 hr at 55 0C

Filter hot through Sparker, collect clear filtrate in crystallizer.Collect clear filtrate in

crystallizer and keep temp 45 0C in crystallizer. Wash sparklers carbon bed with Acetone

and transfer it to crystallizer.Add Hydrose with water then fast add DM Water 15 minutes at

70 0C. Slowly cool to 400C.Apply chilling and chill the material up to 10 oC and maintain for

1 hrs.Centrifuge the material at 10 0C and collect for Acetone Recovery.Wash the cake with

DM water till chloride free, unload material and dry at 90 0C, check LOD and unload from

dryer.

CHEMICAL REACTION:

24

MASS BALANCE:

Input Qty in

Kg

Output

Qty in

Kg

4-Chloro-2- Amino Phenol (4CAP) 0.95 Recoered Methanol 2.85

Urea 0.95 Methanol Loss 0.15

Hydrochloric acid 2.04 ML to ETP (Spent Acid) 2.5

Methanol 3.00 Chlorzoxazone 1.00

Activated Carbon 0.11 Effluent to ETP 1.2

Sulphuric Acid 0.10

Acetic acid 0.50

Sodium Hydrosulphite 0.05

Total 7.7 Total 7.7

25

[7] Aceclofenac


Charge N Dimethyl Amine , Tertiary Butyl Alcohol stirr 1/2 Hrs & unload in clean drum,again

charge Chloro Acetyl Chloride in same reactor chill to 8-10OC.Add mix solution of NNDMA +

T Butanol at 8-10 OC addition time 8-10hrs. Maintain 5 hrs at 8-10 OC, slowly raise Temp up

to 35 OC.Charge water, stirr 1.0 Hr & settle, seperate organic layer from bottom aqueous

layer for NN DMA recovery, organic Layer charge in GLR add water, stirring & separate

bottom organic to give soda ash solution wash to make ph 8.5 to 9.5. Stirr & separate in

organic layer, charge sodium sulphate & filter through 5 Micron cloth. Collect all organic in

GLR and Distilled out product at 85 to 105 OC under vacuum.Charge Reaction mass from

Step 2 with crude Diclofenac Sodium, heat the reaction mass to 80-85 OC, maintain 5 Hrs

and cool to 55 to 60 OC, charge formic acid heat to 48 to 55 OC maintain 8 hrs check TLC,

cool to 40 OC, charge water and Toluene stirring 2 Hrs Centrifuge wash with water.

centrifuge and Unload cake & Dry.

CHEMICAL REACTION:

MASS BALANCE:

26

[8] Fluconazole


Stage-1

To Di-floro acetophenone material, 1,2,4-trizole, Toluene and TMSI is added slowly and the

mass is maintained for about 4 hours, Adjust pH with KOH flakes and kept under

maintenance at 65o-68

oC,Cool to 5

oC and centrifuge, washed with Toluene.The wet material

is charged in to SS tray drier. The Material is air dried for 1 hour and then at 450C to 50

0C

with steam. Drying is continued till LOD content is less than 0.5% w/w. Dried material is

unloaded and taken for next stage of purification.

Stage 2

The stage I material is taken in a reactor and treated with MDC, Citric acid adjust the pH 3.5

with HCL and charcoal and filtered. The filtrate is distilled to remove MDC and the mother

liquor is collected to recover the MDC and the wet material is dried.

CHEMICAL REACTION:

PROCESS FLOW DIAGRAM:

27

MASS BALANCE:

28

29

[9] Niclosamide


Charge xylene in reactor and then add 5 nitro salicyclic acid at room temperature.This is stir

for 1 hour and chilled to 10 C. then slowly charge thionyl chloride at 15° and maintain for 3

hours

Then slowly charge ortho chloro para nitro aniline then stir for 6 hours at 85C. then cooled

to room temperature and centrifuged

ML is collected and recycled. Then extra water is drained to ETP and product is dried and

packed.

CHEMICAL REACTION:

30

MASS BALANCE:

31

[10] 1-(4- Methoxyphenyl)-1-(4-nitrophenyl) piperazine


Charge dimethyl formamide, potassium carbonate and 1-(4-Methyxy) piperazine into a

reactor. Heat the mass to 60-65°C. Add para nitro chloro benzene for 3-4 hours at same

temperature. After completion of the reaction distill off the dimethyl formamide

completely. Cool the mass and charge methanol add carbon into the reactor. Maintain the

mass for 30 minutes at 50-55°C and filter into another reactor. Cool the filtrate to 10-15°C

and centrifuge. Wash the material in water. Slurry wash the cake with acetone to produce 1-

(4- Methoxyphenyl)-1-(4-nitrophenyl) piperazine.

CHEMICAL REACTION:

MASS BALANCE:

32

Process flow chart:

33

[11] 1-(4-Methoxyphenyl) piperazine


1) 100g of p-aminophenol is taken in a mixture of 280 ml water and 180 ml water and 168 g

Bis (2- Chloroethylamine) hydrochloride added. (Actually Bis HCl solution of 65% strength is

used and water adjusted accordingly)

2) At reflux and under nitrogen 106 ml caustic lye solution is added over 9 hr maintaining pH

between 6-6.1.

3) Sodium hydrosulfite is added to decolorize the reaction mass to pale yellow color.

4) After maintaining for 2 hrs, methanol 100 ml is added and stirred for 1 hr. The acetate

salt that precipitates out is filtered and washed with methanol.

5) The above acetate salt is taken in 500ml water and soda ash solution prepared separately

by dissolving 30 g in 150 ml water, is added gradually to bring pH to around 8-8.2.

6) After maintaining at pH 8-8.2 for around 1 hr the pH of the solution is shifted to 5-5.5

using dil HCl and maintained for 0.5 hr.

7) The M1 crude obtained is centrifuged, washed with water and then with methanol.

8) M1 crude is purified by charcoal treatment in a mix of 3:2 methanol water solution (for

100g K3 crude, 500 ml of methanol- water mix is required). pH is first adjusted to 5-5.5,

sodium hydrosulfite added to decolorize, 10 % active charcoal added and refluxed. After 1

hr the solution is filtered hot and sodium hydrosulfite solution added to decolorize the

pinkish color filtrate. The white to light pink colored filtrate is cooled under Nitrogen

atmosphere and filtered to give pure M1. The cake is washed with methanol and dried in

oven at 45-50o C.

CHEMICAL REACTION:

34

Process flow chart:

MASS BALANCE:

35

[12] 6-Methyl pyridine-3 yl-2,4-Methylsulfonyl phenyl Etanone (Ketosulfone)


Charged 4-Methyl thiophenyl acetonitrile in toluene in Reactor at RT.Charged Sodium

Methoxide powder in above reaction mixture slowly at RT.Charged Methyl 6 methyl

nicotinate in RM and was heated and stirred. Add water in above reaction mass.

The reaction mixture was heated and stirred. Now cool the reaction mass.

The separated solid was filtered.

Charged methanol and above solid in Reactor at RT

Cool the reaction mass and add Sulfuric Acid and Sodium Tangustate

Slowly add hydrogen peroxide under stirring with cooling

Cool the reaction mass and separate the wet cake by filtration. Dry the Product

CHEMICAL REACTION:

36

Process Flow diagram:

MASS BALANCE:

Input Qty in

Kg

Output Qty in

Kg

4 Methyl thiophenyl acetonitrile 160 Finished Product 250

Toluene 240 Toluene (Recd) 215

Sodium Methoxide 80 Distillation+ Drying Loss 105

Methyl 6 methyl nicotinate 148 Residue 3

Water 500 Effluent 873

Methanol 150

Sodium Tangustate 3

Hydrogen Peroxide 160

Conc. Sulfuric Acid 5

Total 1446 Total 1446

37

[13] 4 Bromo methyl 2 Cyano biphenyl (Bromo OTBN)


4 Methyl 2 Cyanobiphenyl is Brominated in Presence of Hydrogen Peroxide to get 4 Bromo

Methyl 2 Cyanobiphenyl.The 4-Bromo Methyl Biphenyl is given Ethyl Acetate washings and

subjected to Drying.4 Bromo Methyl Biphenyl is then packed in 50 Kg PPE Bags.

CHEMICAL REACTION:

MASS BALANCE:

38

Annexure -4

___________________________________________________________________________

Details of Water Consumption and Wastewater generation

Water Consumption and Wastewater generation:

S.No. Usage

Water Consumption

(KL/Day)

Waste Water Generation

(KL/Day)

Proposed Proposed

1. Domestic 1.0 0.8

2. Gardening 1.0 --

3. Industrial

4. Process 8.3 9.0

5. Boiler 3.0 0.2

6. Cooling (Make-up) 3.0 0.3

7. Washing 0.5 0.5

8. Sub-Total: Industrial 14.8 10.0

9. Grand Total 16.8 10.8

39

Water Balance:

All figures are in KL/day

Water – 16.8

Domestic- 1.0 Gardening- 1.0 Industrial – 14.8

0.8 KL/Day

� Septic

tank/soak

pit

Process- 8.3 Washing- 0.5 Boiler-3.0 Cooling- 3.0

Process- 9.0 Washing- 0.5 Boiler- 0.2 Cooling- 0.3

ETP (10.0) CETP for further

treatment

40

Annexure -5:

___________________________________________________________________________

Details of ETP

PROCESS DESCRIPTION: ETP (EFFLUENT TREATMENT PLANT)

M/s. Krishna Chemicals shall have an Effluent treatment plant consisting of primary,

secondary and tertiary treatment units. The effluent confirming to inlet standards of CETP.

The details of ETP are as follows.

First all non-toxic and biodegradable streams (low & medium COD) of wastewater shall be

collected in Collection cum Neutralization tank (CNT-01) where the continuous addition and

stirring of Caustic solution is done to maintain neutral pH of wastewater from Caustic Dosing

Tank (CDT-01) as per requirement by gravity. Mixer is provided at bottom of the CNT-01 to

keep all suspended solids in suspension and for proper mixing.

Then after, neutralized wastewater shall be pumped to Flash Mixer (FM-01). Alum and

Polyelectrolyte shall be dosed from Alum Dosing Tank (ADT-01) and Polyelectrolyte Dosing

Tank (PEDT-01) respectively by gravity into FM-01 to carry out coagulation by using a Flash

Mixer.

Then after, coagulated wastewater shall be settled in Primary Settling Tank (PST-1). Clear

supernatant from PST-01 shall be passed in Aeration Tank (AT-01) Here, biodegradation of

organic matter of the wastewater shall be carried out by bacteria (suspended growth) in the

AT-1 and for that oxygen shall be supplied by 2 nos. of air blowers (B-01) through diffusers.

Air blowers also keep MLSS in suspension. Here, the suspended solids shall be settled and

excess activated sludge shall be sent to Sludge Drying Beds (SDBs-01-A/B). Activated sludge

shall be removed from bottom of SST-1 and pumped to AT-1 to maintain MLSS and

remaining will be sent to SDBs-01-A/B. Nutrients will be added from NDTs to Aeration Tank

for growth of Bacteria. Clear effluent is the collected in of Intermediate Sump (IS) by gravity.

Thereafter, the wastewater shall be passed through Dual Media Filter (DMF-01) to remove

left out TSS. After tertiary treatment, effluent shall be collected in Treated Effluent Sump

(TES) before sent to CETP of M/s. PETL for further treatment.

Sludge settled in PST-01 and excess sludge from SST-01 shall be collected in Sludge Drying

Beds (SDBs-01-A/B) where, dewatering shall be carried out before storage in HWSA and

ultimate disposal to TSDF.

41

CHARACTERISTICS OF WASTEWATER BEFORE & AFTER TREATEMENT.

Sr. No. Parameter Characteristics (mg/L) CETP Intel Norms

(mg/L) Untreated Treated

1 pH 5-6 6.5-8.5 5.0-9.0

2 COD (mg/L) < 8000 < 2500 3200

3 BOD3 (mg/L) < 3500 < 700 1000

4 NH3-N (mg/L) < 50 < 50 50

Effluent Treatment Plant (Dimension):

SIZE OF TANKS

S.N. Name of unit Size (m x m x m) No. MOC/

Remark

Stream Flow 10 KLD

1

Collection cum

Neutralization Tank

(CNT-01)

2.5 m x2.5 m x

(2.0 m+0.5 FB) 1

MOC= RCC

M25+A/A Bk.

Lining

2 Flash Mixer (FM-01) 1.0 m x 0.8 m x

(1.5 m +0.5 FB) 1

MOC= RCC

M25

3 Primary Settling Tank

(PST-01)

1.5 m x 1.0 m x

(1.5 m + 0.5 HB+0.5 FB) 1

MOC= RCC

M25

4 Aeration Tank (AT-1) 4.0 m x 2.0 m x

(4.0 m+0.5 m) 1

MOC= RCC

M25

5 Secondary Settling

Tank(SST-01)

1.5 m x 1.0 m x

(1.5 m + 0.5 HB+0.5 FB) 1

MOC= RCC

M25

6 Intermediate Sump (IS) 1.5 m x 1.0 m x

(2.0 m+0.5) 1

MOC= RCC

M25

7 Dual Media Filter (DMF) 1.0 m3/ hr 1 MOC = FRP

9 Treated Effluent Sump

(TES)

5.0 m x2.5 m x

(2.0 m+0.5 FB) 1

MOC= RCC

M25

10 Sludge Drying Beds 3.0m x 2.0 m 2 MOC= Bk.

42

(SDBs-01-A/B) Maso + PCC

Bedding

RCC M25 = REINFORCED CEMENT CONCRETE (M 25 GRADE)

PCC = PLAIN CEMENT CONCRETE

PP = POLYPROPELENE

MSEP = MILD STEEL EPOXY PAINTED

SS = STAINLESS STEEL

43

Flow Diagram:

44

Annexure -6

___________________________________________________________________________

Details of hazardous waste generation, storage & disposal

Type of waste Category Proposed

(MT/Month)

Disposal Method

Discarded

Containers/Bags/

Liners

33.1 200 Nos Collection, Storage, Transportation, reuse/

sale to authorize vendor

Used oil 5.1 10

lit/month

Collection, Storage, Transportation, reuse/

sale to authorize vendor

ETP Sludge 35.1 5

MT/Month

Collection, Storage, transportation and

disposal common TSDF site

Distillation

Residue

20.3 10

MT/Month

Collection, Storage, Transportation and sent

for co-processing in cement industries or

Disposal at common incineration site.

Process Waste -- 5

MT/Month

Collection, Storage, Transportation &

Disposal at TSDF of BEIL, Ankleshwar or

PSWMCL, Panoli.

Spent Carbon 28.3 1.3 Collection, Storage, Transportation &

Disposal at Incinerator Site (BEIL, Ankleshwar)

or sell to cement industry for co-processing.

Inorganic Salt -- 17

MT/Month

Collection, Storage, transportation and

disposal common TSDF site

KCl -- 62

MT/Month

Collection, storage, transportation and sell to

end user.

45

Annexure -7

___________________________________________________________________________

Details of flue gas & proposed pollution control equipment

1. Details of Flue Gas Stack; Stack Attached To Boiler,

2. Details of Process Vent

Sr.

No.

Stack attached

to

Stack

Height

Air Pollution

Control System

Parameter Permissible

Limit

1 Process Vent - 1 11 m Scrubber SO2 40 mg/Nm3

2 Process Vent – 2 11 m Scrubber HCl 20 mg/Nm3

Particulars Fuel Fuel

Quantity

Stack

height

Emission

Norms

APCM

Proposed

Steam Boiler

(Capacity-1.5

MT/Hr)

Agro waste 4 MT/Day 30 m

Particulate matter

<150mg/NM3

SO2 < 100 ppm

NOX < 50 ppm

Multicyclone

Separator, bag

filter

Thermic

Fluid Heater

(Capacity-2

Lakh

Kcal/Hr)

Agro waste 2 MT/Day 30 m Particulate matter

<150mg/NM3

SO2 < 100 ppm

NOX < 50 ppm

Multicyclone

Separator, bag

filter

D.G. Set HSD 5 lit/hr 11 m Particulate matter

<150mg/NM3

SO2 < 100 ppm

NOX < 50 ppm

--

46

Annexure -8

Storage Details of Hazardous Chemicals

Sr.

No.

Raw Materials Storage

Capacity

(MT)

Type of

Storage &

MOC

No. of

Vessel

Vessel

Capacity

(MT)

Type of Hazard

1. Sulfuric acid -98% 6 MS Tank 1

6 Corrosive

2. Hydrobromic acid

(48%)

10 MS Tank 1 10 Corrosive

3. Hydrochloric acid

25 HDPE

Tank

1 25 Corrosive

4. Formic Acid

10 HDPE

Tank

1 10 Toxic/Flammable

5 Acetic Acid 5 Drums

(HDPE)

25 200 lit Corrosive

6 Toluene 2 Drums 10 200 lit Toxic

7 Isopropyl alcohol 2 Drums 10 200 lit Toxic/Flammable

8 Methanol 2 Drums 10 200 lit Toxic

9 Tert Butyl Alcohol 2 Drums 10 200 lit Flammable

10 Xylene 2 Drums 10 200 lit Toxic/Flammable

11 Dimethyl

Formamide

2 Drums 10 200 lit Toxic/Flammable

12 Acetone 2 Drums 10 200 lit Toxic/Flammable

13 Ethyl Acetate 2 Drums 10 200 lit Toxic/Flammable

14 Benzyl Chloride 2 Drums 10 200 lit Toxic/Flammable

15 Thionyl Chloride 2 Drums 10 200 lit Toxic

16 MDC 2 Tank 10 200 lit Toxic

17 Bromine 300 kg Bottle 100 3 kg Toxic

47

Annexure – 9

Socio - Economic Impacts

1) Employment Opportunities

The manpower requirement for the proposed expansion project is being expected to

generate some permanent jobs and secondary jobs for the operation and maintenance of

plant. This will increase direct / indirect employment opportunities and ancillary business

development to some extent for the local population.

This phase is expected to create a beneficial impact on the local socio-economic

environment.

2) Industries

Required raw materials and skilled and unskilled laborers will be utilized maximum from the

local area. The increasing industrial activity will boost the commercial and economical status

of the locality, to some extent.

3) Public Health

The company regularly examines, inspects and tests its emission from sources to make sure

that the emission is below the permissible limit. Hence, there will not be any significant

change in the status of sanitation and the community health of the area, as sufficient

measures have been taken and proposed under the EMP.

4) Transportation and Communication

Since the existing factory is having proper linkage for the transport and communication, the

development of this project will not cause any additional impact.

In brief, as a result of the proposed there will be no adverse impact on sanitation,

communication and community health, as sufficient measures have been proposed to be

taken under the EMP. The proposed scenario is not expected to make any significant change

in the existing status of the socio - economic environment of this region.

48

Annexure-10

__________________________________________________________________________

Proposed Terms of Reference for EIA Studies

1. Project Description

• Justification of project.

• Promoters and their back ground

• Project site location along with site map of 5 km area and site details providing various

industries, surface water bodies, forests etc.

• Project cost

• Project location and Plant layout.

• Existing infrastructure facilities

• Water source and utilization including proposed water balance.

• List of Products & their capacity

• Details of manufacturing process of proposed products

• List of hazardous chemicals

• Mass balance of each product

• Storage and Transportation of raw materials and products.

2. Description of the Environment and Baseline Data Collection

• Micrometeorological data for wind speed, direction, temperature, humidity and rainfall

in 10 km area.

• Existing environmental status Vis a Vis air, water, noise, soil in 10 km area from the

project site.

• Ground water quality at 8 locations within 10 km.

• Complete water balance

3. Socio Economic Data

• Existing socio-economic status, land use pattern and infrastructure facilities available in

the study area were surveyed.

4. Impacts Identification And Mitigatory Measures

• Identification of impacting activities from the proposed project during construction and

operational phase.

• Impact on air and mitigation measures including green belt

• Impact on water environment and mitigation measures

• Soil pollution source and mitigation measures

• Noise generation and control.

• Solid waste quantification and disposal.

• Control of fugitive emissions

5. Environmental Management Plan

• Details of pollution control measures

• Environment management team

• Proposed schedule for environmental monitoring including post project

49

6. Risk Assessment

• Objectives, Philosophy and methodology of risk assessment

• Details on storage facilities

• Process safety, transportation, fire fighting systems, safety features and emergency

capabilities to be adopted.

• Identification of hazards

• Consequence analysis

• Recommendations on the basis of risk assessment done

• Disaster Management Plan.

7. Information for Control of Fugitive Emissions

8. Information on Rain Water Harvesting

9. Green Belt Development plan

50

Annexure-11

__________________________________________________________________________

GIDC Plot Allotment Letter

51

52

Annexure-12

__________________________________________________________________________

GIDC Water Supply Letter

53

Annexure-13

__________________________________________________________________________

CETP Membership Letter

54

Annexure-14

__________________________________________________________________________

BEIL's Common TSDF & CHWIF membership Certificate

55

Annexure-15

__________________________________________________________________________

Toposheet

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