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Report Information from ProQuest13 May 2014
08:44_______________________________________________________________
Document 1 of 1 Blood pressure lowering and stroke Author:
Saini, Monica; Shuaib, Ashfaq ProQuest document link Abstract:
Hypertension is the most prevalent of the modifiable risk factors
for stroke. The benefits of bloodpressure (BP) lowering on primary
and secondary prevention of stroke are undeniable. Despite this, BP
controlin hypertensive individuals and patients with prior
cerebrovascular events is suboptimal. Noncompliance,inappropriate
antihypertensive usage and under-utilization of medications
contribute significantly to inadequateBP control. Recently,
elegantly designed studies that assessed the preventive role of BP
lowering in patientswith cerebrovascular disease have helped
clarify management issues in terms of BP targets and
effectiveantihypertensive regimens. Current evidence suggests that
BP targets for primary and secondary preventionare suboptimal and
need reassessment. The effect of BP modulation in acute stroke is
still not completelyunderstood. Although the thresholds for BP
treatment in acute stroke have been recommended, BP targets areas
yet ill-defined. The available evidence supports early lowering of
blood pressure following stroke. This reviewdiscusses the impact of
blood pressure on stroke incidence and outcomes, outlines the
recommendations forblood pressure lowering in stroke and delineates
questions that still need to be addressed. MeSH: Blood Pressure --
drug effects, Clinical Trials as Topic, Humans, Hypertension --
drug therapy, Stroke --drug therapy, Antihypertensive Agents --
therapeutic use (major), Blood Pressure -- physiology
(major),Hypertension -- complications (major), Stroke -- etiology
(major), Stroke -- prevention & control (major) Substance:
Antihypertensive Agents; Publication title: Expert Review of
Neurotherapeutics Volume: 10 Issue: 2 Pages: 225-41 Publication
year: 2010 Publication date: Feb 2010 Year: 2010 Publisher: Informa
Healthcare, Expert Reviews Ltd. Place of publication: London
Country of publication: United Kingdom Publication subject:
Pharmacy And Pharmacology, Medical Sciences--Psychiatry And
Neurology ISSN: 1473-7175 Source type: Scholarly Journals Language
of publication: English Document type: Review, Journal Article DOI:
http://dx.doi.org/10.1586/ern.09.162 Accession number: 20136379
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pressure lowering and stroke
