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6. 10. 2016 1 Symptoms and syndromes in medicine Tomáš Koller Príznaky a syndrómy v medicíne T.K. T.K. Osnova / Outline 1. Roles in medicine/hospital 2. Nomenclature / terminology 3. Most frequent symptoms in medicine 4. Symptom analysis 5. Clinical signs 6. Clinical diagnosis making 7. Most frequent syndromes/clinical pictures T.K. Osnova / Outline 1. Roles in medicine/hospital T.K. V hlavnej úlohe Leading roles T.K. Vzťahy medzi rolami Role relations Student / young doctor patient Senior doctor Language is different ! T.K.

Prízaky a sydróy v edicíe - FMED UK - Zóna · – Effort (heart/lung disease/anemia) – Breathing – Meal (GIT) – Urination Stool – Sleep (any organ system) Sexual activities

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Page 1: Prízaky a sydróy v edicíe - FMED UK - Zóna · – Effort (heart/lung disease/anemia) – Breathing – Meal (GIT) – Urination Stool – Sleep (any organ system) Sexual activities

6. 10. 2016

1

Symptoms and syndromes in medicine

Tomáš Koller

Príznaky a syndrómy v medicíne

T.K. T.K.

Osnova / Outline

1. Roles in medicine/hospital

2. Nomenclature / terminology

3. Most frequent symptoms in medicine

4. Symptom analysis

5. Clinical signs

6. Clinical diagnosis making

7. Most frequent syndromes/clinical pictures

T.K.

Osnova / Outline

1. Roles in medicine/hospital

T.K.

V hlavnej úlohe Leading roles

T.K.

Vzťahy medzi rolami Role relations

Student / young doctor

patient

Senior doctor

Language is different !

T.K.

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The patient

patient

„....je mi nejako zle“ „....neviem sa nadýchnúť“ „bolí ma .....“ „...neviem prehĺtať“

„i feel unwel...“ „i can´t breathe ...“ „ I feel pain in ...“ „ i can´t eat ...“

- Reč pacienta je laická - Závisí od úrovne vzdelania/intelektu - Od úrovne analýzy príznakov samotným pacientom - Od závažnosti stavu pacienta

- The talk of the patient is unfamiliar with medical terminology - Depends on the level of education/intelect/language - On the analysis of the symptoms by the patients him/herself - On the severity of the disease

T.K.

The student / junior doctor

Cieľ: akú má pacient diagnózu ? Goal: what is the diagnosis ? Prostriedok: klinické vyšetrenie – anamnéza, fyzikálne vyšetrenie Modality: clinical exam – full medical history and full physical exam Cesta/Path: 1. Komunikáciou identifikuj hlavné symptómy pacienta (TO) 2. V prípade nejasností otázky opakuj inými slovami

1. Communicating with the patient identify main symptoms 2. When unclear, repeat questions with different words

T.K.

Senior doctor

„Tell me about the patient“ Expecting to hear: 1. Principle symptoms of the patient 2. Possible connection to the previous medical history/or therapy 3. Principle physical exam findings 4. Clinical diagnosis hypotheses 5. Differential diagnosis hypotheses

„Povedzte mi o pacientovi“ Chce počuť: 1. Hlavné príznaky pacienta 2. Ich možnú súvislosť s OA a liečbou 3. Relevatné nálezy pri fyzikálnom vyšetrení 4. Hypotézy klinickej diagnózy 5. Hypotézy diff. dg.

T.K.

Osnova / Outline

2. Nomenclature / terminology

T.K.

nomenclature 1. a system of names used in the classification of an art or science or other field or subject.

Názvoslovie symtómov Symptom nomeclature

T.K.

Klinický / clinical

T.K.

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slex.sk

Príznak/symptom

T.K.

Symptom nomenclature

• Is internationally standardized

• May have some small regional differences – With regard to the most common

diseases

– With regard to the history of particular school of medicine • Anglo-american, German, French,

Indian, Chinese ...

• Is an alphabet of medicine and medical communication and documentation

• Je medzinárodne štandardizovaná

• Môže mať malé regionálne rozdiely – Kvôli odlišnostiam v

najčastejších chorobách

– Vzhľadom na históriu danej medicínskej školy

• Je abecedou medicíny a medicínskej komunikácie a dokumentácie

T.K.

Symptoms

• No official list of all symptoms

• Usually organ system specific – But can overlap /dyspnea,

fatigue .../

• ICD 10 – WHO • Evolve with time

– New diseases – New knowledge – New investigations

• Neexistuje oficálny úplný zoznam prízakov a syndrómov

• Často sú špecifické pre orgánové systémy – Ale môžu sa prelínať

• Dyspnoe, únava ....

• MKCH 10 – WHO • V čase sa môže meniť

– Nové choroby – Nové poznatky o chorobách – Nové vyšetrovacie metódy

T.K.

Standardized nomenclature

T.K.

T.K.

ICD-10

T.K.

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Osnova / Outline

3. Most frequent symptoms in medicine

T.K.

Celkové príznaky

• Horúčka

• Triaška

• Slabosť/únava

• Kŕče

• Šok

• Zväčšené lymfatické uzliny

• Nadmerné potenie

• Generalizované opuchy

• Kachexia

General symptoms

• Fever

• Chills

• Fatigue/exhaustion

• Seizures

• Shock

• Lymphadenopathy

• Sweating

• Generalized oedema

• Cachexia

Časté príznaky / common symptoms

T.K.

Časté príznaky / common symptoms

Heart and vascular disease

• Chest pain

• Syncope

• Malaise

• Palpitations

• Fatigue

• Dysnea

• Edema

• Claudication

Choroby srdca a ciev

• Bolesti na hrudníku

• Synkopa

• Mdloba

• Palpitácie

• Únava

• Dyspnoe

• Opuchy

• Klaudikácie

T.K.

Choroby pľúc a pleury

• Bolesť na hrudníku

• Kašeľ

• Expektorácia

• Hemoptýza

• Dyspnoe

• Zachrípnutosť

• Čkanie - singultus

Pulmonary and pleural diseases

• Chest pain

• Cough

• Expectoration

• Hemoptysis

• Dyspnea

• Voice alterations

• Hiccups

Časté príznaky / common symptoms

T.K.

Choroby tráviaceho traktu • Nechutenstvo • Anorexia • Bulímia • Dysfágia/odynofágia • Regurgitácia • Pálenie záhy • Nauzea • Vracanie • Hemateméza • Meléna/hematochézia • Zápcha • Hnačka • Ikterus

Digestive tract disease • Loss of apetite • Anorexia • Bulimia • Dysphagia/odynophagia • Regurgitation • Pyrosis • Nausea • Vomiting • Haematemesis • Melaena/hematochezia • Constipation • Diarrhea • Jaundice

Časté príznaky / common symptoms

T.K.

Urologicko-nefrologické

• Polakizúria

• Dyzúria

• Nyktúria

• Anúria

• Retencia moča

• Inkontinencia moča

• Pálenie pri močení

• Hematúria

• Bolesti v lumbálnej oblasti

• Opuchy

Uro-nephrologic

• Pollakisuria

• Dysuria

• Nycturia

• Anuria

• Urine retention

• Urine incontinence

• Haematuria

• Lumbar pain

• Edema

Časté príznaky / common symptoms

T.K.

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Kostno-kĺbový aparát

• Bolesť kĺbov

• Bolesť chrbice

• Opuch kĺbov

• Haemarthros

• Pyartros

• Hydrarthros

Osteoarticular

• Joint pain

• Back pain

• Joint edema

• Haemarthros

• Pyarthros

• Hydrarthros

Časté príznaky / common symptoms

T.K.

Osnova / Outline

4. Symptom analysis

T.K.

Analysis of symptoms

• Should be thorough - exhaustively complete – Should take time and patience

• Friendly relatioship with the patient • But considering the urgency of the situation

– Should be focused on the main symptom (or two) for which the patient is being evaluated • All principle findings should be re-checked – confirmed

during the talk (in other words)

• Should always be followed by brief other organ

system function screening questions – Not to miss important impact on other organ systems

T.K.

Symptom analysis

• Evolution with time: – Since when? – How often? – Character of onset – seconds, minutes, hours, days, months – Duration? – Similar symptoms in the past? – Evolution with time? (more severe/stable), more often/less often)

• Circumstances at which the symptom appears and goes away

• Relation to physiological activities:

– Effort (heart/lung disease/anemia) – Breathing – Meal (GIT) – Urination – Stool – Sleep (any organ system) – Sexual activities

days/months

T.K.

Symptom analysis

• Exact location (will guide the focused physical examination) – Pain – Itching – Burning – Skin lesions

• Severity scale – 0-10 for pain – Solid food/liquid food

• Character of the symptom

– Pain – sharp, dull, burning, throbbing, pressing....

• Functional impact on daily acitivities – Work – Self-care – Eating – Drinking – Sleeping – Walking

T.K.

Symptom analysis

• All other associated symptoms

– General

– Localized

T.K.

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Osnova / Outline

5. Clinical signs

T.K.

Klinický znak/clinical sign

T.K.

syndrome

Syndróm sa skladá minimálne 1 z: Syndrome consists of one or more of: Príznakov Symptoms Znakov Clinical signs (Laboratórny nález) (Labs) (Zobrazovací nález) (Imaging)

T.K.

Osnova / Outline

6. Clinical diagnosis making

T.K.

Basic terms

• Clinical diagnosis – Diagnosis suggested by the symptom analysis and observed

clinical signs » E.g. progressive dyphagia for liquids, then solids with severe

malnutrition

• Differential diagnosis

– All possible diseases with similar clinical picture » E.g. oesophageal cancer, achalasia, large goiter, mediastinal mass ....

• Etiological diagnosis

– The disease (one) that caused the current condition of the patient

» E.g. Proximal squamous oesophageal carcinoma T3N1M0 » Using upper endoscopy, histology, CT scan

T.K.

What is it?

T.K.

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Príznak/symptom 1.

Klinický znak/clinical sign 1.

Etiologická diagnóza/etiological diagnosis

Príznak/symptom 2.

Príznak/symptom 3.

Klinický znak/clinical sign 2.

Klinický znak/clinical sign 3.

Diferenciálna diagnóza/differencial diagnosis

Čas/time Easy case

T.K.

Príznak/symptom 1.

Klinický znak/clinical sign 1.

Etiologická diagnóza/etiological diagnosis

Príznak/symptom 2.

Príznak/symptom 3.

Klinický znak/clinical sign 2.

Klinický znak/clinical sign 3.

Diferenciálna diagnóza/differencial diagnosis

Čas/time Uneasy case

T.K.

Príznak/symptom 1.

Klinický znak/clinical sign 1.

Etiologická diagnóza/etiological diagnosis

Príznak/symptom 2.

Príznak/symptom 3.

Klinický znak/clinical sign 2.

Klinický znak/clinical sign 3.

Diferenciálna diagnóza/differencial diagnosis

Čas/time

Laboratory result 1.

Laboratory result 2.

Imaging 2.

Confirmatiory exams

Imaging 1.

T.K.

More pieces of the puzzle

T.K.

Etiological diagnosis

• Can be synthetized from a mosaic of indices – Clinical diagnosis – symptoms + signs – Risk factors – Personal history – Lab results and imaging

OR

• a diagnostic test

– Test that confirms the diagnosis – Is defined and interpreted exactly (e.g. troponin, histology) – Not all diagnoses have one (rheumatological dis.)

T.K.

Etiological diagnosis

• When the disease begins – Only few indices pointing to the

disease are detectable

BUT

– Disease more likey curative

• More the disease progresses – More indices pointing to it are

detectable

BUT

– Less likely the therapy will be curative (cancer)

T.K.

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Osnova / Outline

7. Most frequent syndromes/clinical pictures

T.K.

Heart failure

T.K.

Angina pectoris

T.K.

Variants of angina pectoris

T.K.

T.K.

Pulmonary embolism

T.K.

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T.K.

T.K.

Chronic Obstructive Pulmonary Dis.

T.K.

T.K.

Pulmonary malignancy

Superior vena cava syndrome Pancoast syndrome

T.K. T.K.

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Biliary pain

Torsion, spasm

Continuous

Paroxysmal aggravation

Very strong

Rapidly progressive

Hours, night

T.K.

Colic pain

Paroxysmal

Strong

Spasms, distention

Short – minutes

Diarhea

Gas

Fever

T.K.

Small intestine – obstructional syndrome

Spasms

Quick installation

Repeating waves of

pain of short duration

Minutes

Not maximal

T.K.

Gastro-oesophageal reflux pain

Burning

Seconds, minutes

After meals

T.K.

Peptic ulcer pain

Spasm, torsion like

Hunger like

Minutes, hours

T.K.

Tearing pain

Spasms

Very strong

Continuous

After meal

Pancreatic pain

T.K.

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Ascites – portal hypertension

T.K. T.K.

T.K.

Hypothyroidism

T.K.

Acromegaly Growth hormone overproduction

T.K.

Cachexia

T.K.

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Nephrotic syndrome

T.K.

Pre-eclampsia

T.K.

Summary

• Symptoms and signs – alphabet of medicine

• absolutely

• Clinical diagnosis – By the bed of the patient

• Differential diagnosis – All possible conditions

possibly causing the clinical diagnosis

• Etiological diagnosis – The disease that caused the

current problem

– Chapters in medical books

• Symptom analysis a physical examination makes the clinical diagnosis and most of the etiological diagnosis – Cornerstone of your clinical

teaching

– Takes time and patience

– Requires appropriate language (Slovak too!)

– Should never be ommited when managing any patient at any situation

– Improves with practice all your carrier

T.K. T.K.