Upload
forrest-beck
View
33
Download
0
Embed Size (px)
DESCRIPTION
Pulmonary Interstitial Lymphography. Pulmonary Interstitial Lymphography. Primary Nodal Drainage Square = primary tumor Circle = primary drainage. Treatment Planning per 0813. - PowerPoint PPT Presentation
Citation preview
CurrentGoldStandard
•Surgery remains gold standard for early stage lung cancer•Many patients cannot or prefer to not undergo surgery•SBRT/ SABR is emerging, improving alternative
•Radiosurgery targets only primary tumor•Control at 1O site excellent•But +/- 15% recur regionally (with T1& T2 patients, adequate follow up, imaging at follow-up & actuarial method)
•Identify regions at highest risk of micro-metastatic disease•Deliver ablative radiation to primary nodal drainage
Problem
Concept Under Investigation
Pulmonary Interstitial Lymphography
Pulmonary Interstitial Lymphography
Primary Nodal DrainageSquare = primary tumor
Circle = primary drainage
5 fractions, simultaneous integrated boost RapidArc, >340 d
PTV 50 Gy (primary tumor) coverage Normalized to 95%
PTV 35 Gy (nodal drainage) coverage (all >, med) 95%, 99.6%
Modulation: MU/cGy ratio (med, max) 2.8, 3.3
Conformality: V50/ PTV volume (med, max) 1.07, 1.10
NTC: Spinal cord V13.5 (med, max) 0.00, 0.20 cc
NTC: Cent airway V18 (med, max) 8.5, 17.2 cc
NTC: Total lung V20 (med, max) 5.5, 7.6%
NTC: Esophagus V27.5 (med, max) 0.0, 9.7 cc
NTC: Heart V32, Gr Vessells V47 (med) 0.10, 0.00
Treatment Planning per 0813