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Pupil centre shift between bright light and dim light conditions. C. Winkler von Mohrenfels 1 , J Salgado 1, R. Khoramnia 1 , Christian Wüllner 2 , Peter Riedel 2 , C Donitzky 2 1Augenklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany, Financial interest: none - PowerPoint PPT Presentation
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Klinik und Poliklinik für Augenheilkunde
Pupil centre shift between bright
light and dim light conditionsC. Winkler von Mohrenfels1, J Salgado1, R. Khoramnia1, Christian
Wüllner2, Peter Riedel2, C Donitzky2
1Augenklinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany, Financial interest: none
2 WaveLight AG Erlangen, financial interest: employee
Klinik und Poliklinik für Augenheilkunde
ASCRS 2010 2
Problem
- different pupil size between dim and bright light condition
- centration of laser ablation: pupil center, apex, line of sight
- eye tracking: pupil, iris
- pupil shift between the different light conditions could lead to
miss alignment of the laser ablation.
Method
- 47 healthy subjects both eyes (12♂, 35 ♀),
- mean age 36 years (range 23 to 60)
- WaveLight Allegro Topolyzer: Pupil software (dim [20 lux] and bright
light [455 lux] conditions)
Klinik und Poliklinik für Augenheilkunde
ASCRS 2010 3
Pupil difference and age
y = -0.0252x + 3.8457R2 = 0.2163
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
4.5
5.0
10 20 30 40 50 60 70
age in [years]
Pu
pil
dev
itio
n b
etw
een
dim
an
d b
ritg
h l
igh
t co
nd
itio
ns
in [
mm
]
Klinik und Poliklinik für Augenheilkunde
ASCRS 2010 4
Pupil center shift right eye
MW 105µm (SD 65; min 18µm; max 330µm)
-0.5
-0.4
-0.3
-0.2
-0.1
0.0
0.1
0.2
0.3
0.4
0.5
-0.5 -0.4 -0.3 -0.2 -0.1 0.0 0.1 0.2 0.3 0.4 0.5
x axis
• y-a
xis
nasaltemporal
Klinik und Poliklinik für Augenheilkunde
ASCRS 2010 5
Pupil center shift left eye
MW 107µm (SD 64; min 11µm; max 348µm) -0.5
-0.4
-0.3
-0.2
-0.1
0.0
0.1
0.2
0.3
0.4
0.5
-0.5 -0.4 -0.3 -0.2 -0.1 0.0 0.1 0.2 0.3 0.4 0.5
x-axis
y- a
xis
temporalnasal
Klinik und Poliklinik für Augenheilkunde
ASCRS 2010 6
Conclusions
- the average pupil shift is 0.11mm
- most pupils shift to temporal side
- huge variation 0.01mm to 0.348mm
- the larger pupils shifts could lead to a miss alignment
between tracking and laser ablation.
→ risk of decentration and poor visual outcome
