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PURE; Advanced Dietary Interventions for Detoxification
Kristi Hughes, ND Sydney, Australia June 2014
Gather Organize
©2014 The Institute for Functional Medicine
25 57
Weight Gain/Inc Waist Circ Hypertension Dyslipidemia
Fatigue/Reduce Stamina
50
Electrician; working on construction sites since mid 20s
Weight Gain & Fatigue
Hypertension Incr Chol & LDL
Avid exerciser and runner Reduced exercise
Loves to cook “foodie”
Increased Triglycerides
Incr glucose
Carol’s plan
52 54
©2014 The Institute for Functional Medicine
Obesity, VAT (Incr WHR) Hypertension Endothelial Dysfunction??? Joint stiffness morning
Mild Testosterone Deficiency??? Insulin Resistance??? Insulin Resistance???
Blood Sugar Elevation HTN and Met Syn???
Occupational Exposure
Fatigue Muscle Soreness
Obesity, VAT (Incr WHR) Endothelial Dysfunction??? Joint stiffness morning
?
©2014 The Institute for Functional Medicine
Dave’s Initial Therapeutic PlanSupplements On
RisingBkfst Mid
MornLunch Mid
AfternSupper Mid
EvenBeforeBed
DuringNight
What’s Your Plan for Dave?
Nutrition Assessments
PFC-MVP Biomarkers
Gather Organize Re-Tell
Order/Prioritize The ABCDs of
Nutrition Evaluation
Nutrition Therapeutic Interventions
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
Clinical Nutrition Findings Core Food Plan Elimination Diet Cardiometabolic Medical History Seeking Healthy Diet, All Ages,
Athletic, Pregnancy, Overweight, Overweight, Underweight.
Allergies, Atopy, Asthma, GI Distress, Pain and Fatigue, AI Diseases.
Metabolic Syndrome, Type 2 Diabetes, Hypertension, Dyslipidemia, Obesity
ATMs Antibiotics, Multiple infections, Trauma, Stress, Familial allergies, Mother with Group B strep, Acid Blocking Medication, Maternal use of PPI during pregnancy
Family History, T2DM, CVD, HTN, Obesity, Sedentary Lifestyle, Sleep Disorder (inadequate sleep and Sleep apnea)
Anthropometrics Non-specific Increased BMI, Increased ECW/ICW Incr: BMI, WC, WHR, Fat, Blood Pressure
Biomarkers & Labs Normal screening values Incr. IgG or IgE food reactions, Celiac, Autoantibodies, Dysbiosis.
Incr: HgbA1C, FBS, insulin, hs-CRP, TrigsDecr: HDL
Clinical Indicators fromNutrition Physical Exam
Non-specific Dry Skin, thin eyebrows, Fluid retention, and skin inflammation.
Incr: WC and WHRSkin tags, acanthosis nigricans, peripheral neuropathy.
Diet and Lifestyle Inadequate nutrientsPrepared food
Food Triggers, Allergy Exposures. Excess reliance on one food.
Excess simple sugarHigh CHO intake, GI foods, low protein, excess alcohol, elevated trans fats.
Matrix Patterns Non-specific AssimilationBiotransformationCommunication/Defense and Repair
Structural IntegrityTransportDefend and Repair/Communication
CardiometabolicMetabolic Syndrome, Type 2 Diabetes, Hypertension, Dyslipidemia, Obesity
Trauma, Stress, Familial allergies, Mother with Group B strep, Acid Blocking Medication, Maternal use of
Family History, T2DM, CVD, HTN, Obesity, Sedentary Lifestyle, Sleep Disorder (inadequate sleep and Sleep apnea)
Increased BMI, Increased ECW/ICW Incr: BMI, WC, WHR, Fat, Blood Pressure
Celiac, Autoantibodies, Dysbiosis.Incr: HgbA1C, FBS, insulin, hs-CRP, TrigsDecr: HDL
retention, and skin inflammation.Incr: WC and WHRSkin tags, acanthosis nigricans, peripheral neuropathy.
Food Triggers, Allergy Exposures. Excess simple sugarHigh CHO intake, GI foods, low protein, excess alcohol, elevated trans fats.
Communication/Defense and Repair
Structural IntegrityTransportDefend and Repair/Communication
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
Dave’s Initial Therapeutic PlanSupplements On
RisingBkfst Mid
MornLunch Mid
AfternSupper Mid
EvenBeforeBed
DuringNight
Metabolic Food Plan
MultiVM with Phytonutrients
1
Anti-inflammatory hops extract
1 1
EPA/DHA 3:2 720 mg
2 1
Insulin sensitizing combo
2 2 2
Liver detoxification formula
2
D3 5000 1
©2014 The Institute for Functional Medicine
O T T G G OG
Gather Oneself & Information
Organize on Timeline & Matrix
Tell the Patient’s Story
Order of your Priorities
Initiate Assessment and Care
Track Progress O I
Lost 34.4 lbs Lost 24.1 lbs of fat Dropped 3.1 L Moved fluid into the cell BP normalized
2 Years Later; Making Progress and Time to Re-evaluation
Lost 34.4 lbs BP normalized Gluc, Insulin, HgbA1C Trig 216 -> 88 Vitamin D improved Testosterone improved
Cholesterol-No Change LDL-no change Apo B/A1 .85
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
Inflammation VAT (Incr WHR) Low D InflamVascular Risks
Fatigue Muscle Soreness Oxidative Stress
Mild Testosterone Def Insulin Resistance Metabolic Syndrome
Insulin Resistance Blood Sugar Elevation HTN and Met Syn
Occupational Exposure Lead exposure Heavy Metal concern Low Glutathione
Obesity Overweight VAT (Incr WHR) Hypertension Endothelial Dysfunction Erectile Dysfunction Joint Stiffness
Adequate and Restful
Consistent walking and
jogging
Low Anti-oxid Reduced Magnesium Methylation concerns Low B2, B6, B12, Folic Acid
Moving, job satisfaction, excited about change to position for retirement ,
happy in marriage
©2014 The Institute for Functional Medicine
Pattern Recognition
Undernourished
Reduce Exposures
Ensure a Safe Detox
©2014 The Institute for Functional Medicine
Dave’s Initial Therapeutic PlanSupplements On
RisingBkfst Mid
MornLunch Mid
AfternSupper Mid
EvenBeforeBed
DuringNight
What’s Your NEW Plan for Dave?
Dave’s Updated Therapeutic PlanSupplements On
RisingBkfst Mid
MornLunch Mid
AfternSupper Mid
EvenBeforeBed
DuringNight
Detox Food Plan
EFAs 600 (3:2) 1 1
MetaglycemX 2 2
Advaclear 2
Glutaclear (NAC/Vit C) 2 2
D3 5000 1
(Renew) Metallaclear 1 1
Heavy Metal Detox Rotations of oral chelation with EDTA and DMSA
Bowel Motility Ensure daily bowel elimination
FIRST
©2014 The Institute for Functional Medicine
FIRST
FIRST
Inflammation VAT (Incr WHR) Low D InflamVascular Risks
Fatigue Muscle Soreness Oxidative Stress
Mild Testosterone Def Insulin Resistance Metabolic Syndrome
Insulin Resistance Blood Sugar Elevation HTN and Met Syn
Occupational Exposure Lead exposure Heavy Metal concern Low Glutathione
Obesity Overweight VAT (Incr WHR) Hypertension Endothelial Dysfunction Erectile Dysfunction Joint Stiffness
Adequate and Restful
Consistent walking and
jogging
Low Anti-oxid Reduced Magnesium Methylation concerns Low B2, B6, B12, Folic Acid
Moving, job satisfaction, excited about change to position for retirement ,
happy in marriage
Inflammation VAT (Incr WHR) Low D InflamVascular Risks
Fatigue Muscle Soreness Oxidative Stress
Mild Testosterone Def Insulin Resistance Metabolic Syndrome
Insulin Resistance Blood Sugar Elevation HTN and Met Syn
Occupational Exposure Lead exposure Heavy Metal concern Low Glutathione
Obesity Overweight VAT (Incr WHR) Hypertension Endothelial Dysfunction Erectile Dysfunction Joint Stiffness
Adequate and Restful
Consistent walking and
jogging
Low Anti-oxid Reduced Magnesium Methylation concerns Low B2, B6, B12, Folic Acid
Moving, job satisfaction, excited about change to position for retirement ,
happy in marriage
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
Food Plays a Role in All Phases of Detoxification
Toxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
FOOD
Sequencing a Detox Program
©2014 The Institute for Functional Medicine
REMOVE (5R) Detox Foods
1 2
Reduce or Remove •Alcohol & Caffeine •Artificial Sweeteners •Fats & Sugar •High Allergen Foods •Environmental Toxicants •Toxic Habits •Stressors
Therapeutic Intervention Personalize
3 4
©2014 The Institute for Functional Medicine
Ideas on Eating CleanToxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
Food ProductsFood PackagingFood Preparation
©2014 The Institute for Functional Medicine
Ideas on Eating Clean
Food Products Food Packaging Food Preparation
Organically grown Whole foods Slow, low cooking
Non-GMO No plastic casing No deep frying
No synthetic dyes or additives No metal cans (BPA) No significant browning
Grass-fed, lean meats No cellophane or foil Use intact cookware without scuffs
Wild-caught fish Glass preferred Choose non-toxic pans, pots, skillets
Expeller-pressed, unrefined oils No high heat
Filtered water
Org
anic
& C
lean
Foo
d
Remove Toxic Foods
Food toxins include:
– Petrochemical residues from some farming practices
– Mercury from industrial waste in fish
– Lead in the water – Advanced glycation
endproducts (AGEs) from food preparation (overcooking)
– Polyaromatic hydrocarbons from charbroiled meat
– Trans fats – Naturally-occurring plant toxins
(e.g., aflatoxin)
How to Limit Exposure to Pesticides
• Do not overconsume foods that concentrate pesticides (animal fat, meat, eggs, cheese, milk)
• Buy organic produce • Try to buy local produce in
season • Peel off the skin or remove
outer later of leaves of some produce.
• Remove surface pesticide residues, waxes, fungicides, and fertilizers by soaking the food in a mild solution of additive-free soap (pure castille soap, biodegradable cleanser).
• Use scrub brush
©2014 The Institute for Functional Medicine
Include Clean, Nourishing FoodsEat foods which:
– Nourish the organs of detoxification (e.g., liver)
– Provide substrates and cofactors for optimal detoxification through cellular, hepatic, gastrointestinal, and renal mechanisms
– Modify genetic expression
– Provide phytochemicals that impact cellular signaling
REMOVE (5R) Detox Foods
1 2
Reduce or Remove •Alcohol & Caffeine •Artificial Sweeteners •Fats & Sugar •High Allergen Foods •Environmental Toxicants •Toxic Habits •Stressors
Therapeutic Intervention Personalize
3 4
Elimination Diet
Features of the Elimination Diet
The Elimination Diet
Reduces Inflammation
Repairs Intestinal
Permeability
Phytonutrients to Heal the Gut
Personalized Diet Approach
Reduces Toxic Burden
No Calorie Restriction
Promotes Body Awareness to
Foods
Identifies Food Triggers
REMOVE (5R) Detox Foods
1 2
Reduce or Remove •Alcohol & Caffeine •Artificial Sweeteners •Fats & Sugar •High Allergen Foods •Environmental Toxicants •Toxic Habits •Stressors
May Include •Vegetables •Citrus •Protein •Good Oils •Fiber •Water •Herb
Therapeutic Intervention
3 4
Phyto Spectrum Elimination Diet
Personalize
What is the Importance of Phytonutrients in Detox?
Phytonutrient Diversity
The Power of Phytochemical Diversity
“These findings indicate that botanical diversity plays a role in determining the bioactivity of high-VF diets and that smaller amounts of many phytochemicals may have greater beneficial effects than larger amounts of fewer phytochemicals.”
J Nutr.2006 Aug;136(8):2207-12. Dietary botanical diversity affects the reduction of oxidative biomarkers in women due to high vegetable and fruit intake. Thompson HJ, Heimendinger J, Diker A, O'Neill C, Haegele A, Meineck B, Wolfe P, Sedlacek S, Zhu Z, Jiang W.
Carbohydrate = 250 gramsProtein = 100 grams Fat = 60 gramsPhytonutrients = 1.5 grams
We eat less than a teaspoon a day but they make a huge impact!
Walsh et al., Am J Clin Nutr. 2007 Dec;86(6):1687-93.
Fat Phytonutrients
Walsh et al., Am J Clin Nutr. 2007 Dec;86(6):1687
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
Aim for 9-13 Servings of Plant Foods Everyday
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
Know Your Phytonutrient Sources
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
Eat the Rainbow of Colors
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
Vary Your Choices
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
Maximize Combinations
©2014 The Institute for Functional Medicine
6 Steps to Getting More Phytonutrients
Be Creative with Substitutions
Plants as Detox Modulators
68
Liu, Adv. Nutr. 4: 384S–392S, 2013.
• FODMAP • SCD • GAPS • Anti-Candida
Re-introduction Challenge Foods
???
Take Detox Focused Approach
REMOVE (5R) Detox Foods
1 2
Reduce or Remove •Alcohol & Caffeine •Artificial Sweeteners •Fats & Sugar •High Allergen Foods •Environmental Toxicants •Toxic Habits •Stressors
May Include •Vegetables •Citrus •Protein •Good Oils •Fiber •Water •Herb
Therapeutic Intervention
Therapeutic Intervention •Nutraceuticals •Botanicals •Medical or Functional Food •Liquid Fasting •Chelation Therapy •Hydrotherapy •Homeopathic Drainage
3 4
Phyto Spectrum
Elimination Diet
Personalize
Detox Food Plan
REMOVE (5R) Detox Foods
1 2
Reduce or Remove •Alcohol & Caffeine •Artificial Sweeteners •Fats & Sugar •High Allergen Foods •Environmental Toxicants •Toxic Habits •Stressors
May Include •Vegetables •Citrus •Protein •Good Oils •Fiber •Water •Herb
Therapeutic Intervention
Therapeutic Intervention •Nutraceuticals •Botanicals •Medical or Functional Food •Liquid Fasting •Chelation Therapy •Hydrotherapy •Homeopathic Drainage
3 4
Detox Food Plan
Phyto Spectrum
Elimination Diet
Personalize
Introducing the
Detox Food Plan
Tailored to maximize the therapeutic quality of nutrients in all phases of detoxification
©2014 The Institute for Functional Medicine
Why is Food Important to
Your Patient’s
Detoxification Process?
©2014 The Institute for Functional Medicine
Food Plays a Role in All Phases of Detoxification
Toxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
FOOD
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
©2014 The Institute for Functional Medicine
Phase I Nutrients and Food Sources on the Detox Food Plan
Toxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
Nutrient Food Sources Riboflavin (vitamin B2) Soybeans, spinach, tempeh, crimini mushrooms, eggs, asparagus, almonds,
turkey Niacin (vitamin B3) Tuna, chicken, turkey, salmon, lamb, beef, sardines, brown rice Pyridoxine (vitamin B6) Tuna, turkey, beef, chicken, salmon, sweet potato, potato, sunflower seeds,
spinach, banana Folic acid Lentils, pinto beans, garbanzo beans, black beans, navy beans, turnip
greens, broccoli Vitamin B12 Choose methylcobalamin for supplemental source, sardines, salmon, tuna,
cod, lamb beef Glutathione Undenatured whey protein, asparagus, curcumin, broccoli, avocado,
spinach, garlic, foods high in vitamin C (e.g., citrus fruits) and selenium (e.g., Brazil nuts)
Branched-chain amino acids
Whey protein, chicken, fish, eggs
Flavonoids Virtually all plant foods, including apples, apricots, blueberries, pears, raspberries, strawberries, black beans, cabbage, onions, parsley, pinto beans, and tomatoes
Phospholipids Soy, sunflower seeds, eggs
©2014 The Institute for Functional Medicine
Antioxidant Nutrients and Phytonutrients that Protect Against Overproduction of Phase I Metabolites
Nutrient Food Sources Carotenes (vitamin A) Essentially all red, orange, yellow, and green plant foods Ascorbic acid (vitamin C) All will be higher in vitamin C if uncooked: Bell peppers, papaya, citrus fruits, broccoli,
Brussels sprouts, strawberries, kiwi Tocopherols (vitamin E) Sunflower seeds, almonds, spinach, Swiss chard, avocado, turnip greens, asparagus,
mustard greens Selenium Brazil nuts, tuna, sardines, salmon, turkey, cod, chicken, lamb, beef Copper Sesame seeds, cashews, soybeans, mushrooms (shiitake), sunflower seeds, tempeh,
garbanzo beans, lentils, walnuts, lima beans Zinc Beef, lamb, sesame seeds, pumpkin seeds, lentils, garbanzo beans, cashews, quinoa,
turkey Manganese Cloves, (gluten-free) oats, brown rice, garbanzo beans, spinach, pineapple, pumpkin
seeds, tempeh, soybeans Coenzyme Q10 Meat, poultry, fish Thiols Chives, daikon radishes, garlic, leeks, onions, scallions, shallots Flavonoids Virtually all plant foods, including apples, apricots, blueberries, pears, raspberries,
strawberries, black beans, cabbage, onions, parsley, pinto beans, and tomatoes Silymarin Milk thistle (herb), artichokes Pycnogenol Small amounts in the peels, skins, or seeds of grapes, blueberries, cherries, and plums
Toxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
©2014 The Institute for Functional Medicine
Nutrients for Phase II Conjugation Pathways
Nutrient Food Sources
Glycine Beef, chicken, lamb
Taurine Fish, meat
Glutamine Beef, chicken, fish, eggs, cabbage, beets, beans, spinach, and parsley
N-acetylcysteine Most high-protein foods (e.g., chicken), garlic, cruciferous vegetables
Cysteine Beef, chicken, lamb, fish
Methionine Egg white/whole egg, sesame seeds, Brazil nuts, soy protein, chicken, tuna, beef, chickpea, almonds, pinto beans, lentils, brown rice
Toxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
Features of the Detox Food Plan
Therapeutic Dietary Interventions: The Detoxification Food Plan
Reduces Known Food Triggers
Choose Clean and Organic
Foods
Balances Hormone
Metabolism
Fasting and Calorie Options
Phytonutrients for Gut, Liver,
and Kidney
Targeted Anti-oxidants
High Fiber for Optimal
Elimination
Adequate Protein to Aid Detox
Key Features of the Detox Food Plan • Builds on food trigger identification and continues with a
targeted nutrients to support detox pathways • Supports liver function with high-quality protein • Encourages a more specific personalized dietary approach
by targeting hepatic detoxification enzymes and tailoring nutrients to liver-specific needs
• High in phytonutrient density for gut, liver, and kidney • Targeted anti-oxidants to support the reduction of body
toxin burden and impact of incoming toxin load • Fasting and Calorie-specific options or non-calorie plan • Encourages high fiber to create optimal elimination of
toxins and endotoxins • Balances hormone metabolism
Touring Your Patient through the Food Plan
Features of Detox Food Plan High-Quality Protein
• Women 8-10 servings daily/Men 10-12 servings per day• Focus on highlighted foods for detox emphasis• Adequate protein required for detox• Ensure patient can digest protein• Remove allergenic protein sources (may need to be
individualized)• Vegetarian and non-vegetarian options
How Can You Facilitate Phase II
Detox in Your Patient?
• Protein/Amino Acids– Sulfate– Methyl groups– Glucuronic acid– Glutathione
• Compounds to stimulate glutathione production
Toxins InToxins In
Phase I Phase I SupportPhase I SupportSupport
Phase I Phase I Protection Protection Protection
Phase II Phase II SupportPhase II SupportSupport
Toxins OutToxins Out
Features of Detox Food Plan Legumes:• 2-4 servings per day• Focus on highlighted foods for detox emphasis• Good protein source for vegetarians• Encourage variety in colors for broad array of
phytochemical support• Source of fiber
Legumes
Features of Detox Food Plan LF Dairy Alternatives:• 2-4 servings daily (not required, may sub for other
proteins/carbs at practitioners discretion)• Focus on highlighted foods for detox emphasis• Eliminate dairy-containing foods to reduce potential
allergenic load and toxin storage in animal fat• Seed milks conducive to liver detox pathways• Coconut milk as good energy source during detox• Ensure unsweetened varieties of all products
Low-FatDairy
Alternatives
• Unfiltered, cold-pressed, organic preferred, non-GMO• 4-8 servings daily on average• Quality of oils is key• Reduction of processed, inflammatory, high-omega-6 oils• Spectrum of short-, medium, and long-chain fats• Omission of dairy-derived fats• Note oils to cook with and not cook with
Features of Detox Food Plan Fats & Oils
Therapeutic Foods: Fats & Oils
• Avocado • Clarified butter (ghee) • Coconut oil • Extra virgin olive oil • Flaxseed oil • Rice bran oil • Sesame oil
Features of Detox Food Plan Nuts & Seeds
• Up to 4 servings daily (based on other protein amounts)• Focus on highlighted foods for detox emphasis• Include in smoothies for added protein• Provides fiber and healthy fats for detox• Soaked, sprouted or lightly roasted for patients with
impaired digestion• Watch for inclusion of poor-quality oils• Remove allergenic peanuts/peanut butter
Therapeutic Foods: Nuts & Seeds
• All of the nuts, seeds and their respective butters or pastes
• Special focus on sesame seeds and flaxseeds for detox
Features of Detox Food Plan Non-starchy Vegetables
• Recommend consuming 8 or more servings daily• Focus on highlighted foods for detox emphasis• Ensure servings from specified categories for additional detox support• Source of fiber for proper elimination• Phytochemical variety essential• Stimulates healthy bile flow
Therapeutic Foods: Non-Starchy Vegetables
• Brassicales • Detoxifying Leafy Greens • Thiols • Liver & Kidney Support
High dietary intake of vegetables and fruits result in a reduced
dietary net acid load (and improved alkalinization) and
indirectly improves detoxification processes.
Proudfoot et al. J Tox Clin Tox 2004Remer and Manz, J Am Diet Assoc. 1995; 95:791-797.
Features of Detox Food Plan Starchy Vegetables:• Up to 1-4 servings daily based on Metabolic Concerns• Focus on highlighted foods for detox emphasis• Encourage variety in colors for broad array of
phytochemical support• Source of fiber• Eliminate corn to reduce potential allergenic load• Consider GI specific Plan options (FODMAP)
Starchy Vegetables
Therapeutic Foods: Starchy Vegetables
• Beets • Celeriac
Features of Detox Food Plan Fruits:• 2-4 servings daily of unsweetened fruits based on other GI
considerations, may help with sugar cravings• Focus on highlighted foods for detox emphasis• Ensure variety for colorful spectrum of phytochemicals to
support detox process• Watch for grapefruit if reduced CYP3A4 activity• Antioxidants to reduce Phase I production of reactive
metabolites• Source of fiber and water for healthy excretion
Fruits
Features of Detox Food Plan GF Grains:• Ideally limit servings daily to no more than 2• Focus on highlighted foods for detox emphasis• Ensure variety for colorful spectrum of phytochemicals to
support detox process• Eliminate gluten to reduce allergenic load and potential
inflammation, consider GI specific Plan (FODMAP)• Antioxidants to reduce Phase I production of reactive
metabolites
Gluten-Free Grains
REMOVE (5R) Detox Foods
1 2Therapeutic Intervention
3 4Personalize
May Include •Food challenges •Re-introduction •Assess Reactions •Ongoing Support
•Bowel Support •Kidney Support •Liver Support
•Dental work
Food Plan That You Love
REMOVE (5R) Detox Foods
1 2
Reduce or Remove •Alcohol & Caffeine •Artificial Sweeteners •Fats & Sugar •High Allergen Foods •Environmental Toxicants •Toxic Habits •Stressors
May Include •Vegetables •Citrus •Protein •Good Oils •Fiber •Water •Herb
Therapeutic Intervention
Therapeutic Intervention •Nutraceuticals •Botanicals •Medical or Functional Food •Liquid Fasting •Chelation Therapy •Hydrotherapy •Homeopathic Drainage
3 4
Detox Food Plan
Phyto Spectrum
Elimination Diet
Personalize
May Include •Food challenges •Re-introduction •Assess Reactions •Ongoing Support
•Bowel Support •Kidney Support •Liver Support
•Dental work
Our Mission:To inform people about toxicity and inspire them to healthy solutions
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