Randomness Testing Randomness Testing in DNA Samplesin DNA Samples

Laura Jean ChampagneLaura Jean Champagne

Advisor: Gary DavisAdvisor: Gary Davis

AbstractAbstract

►This project examines the randomization This project examines the randomization of DNA sequences based on current of DNA sequences based on current genome sequencing projects. Using genome sequencing projects. Using computational programs, mainly R and computational programs, mainly R and MATLAB, different mathematical tests for MATLAB, different mathematical tests for randomness are applied to DNA randomness are applied to DNA sequences in an attempt to find patterns sequences in an attempt to find patterns or other unique properties. DNA or other unique properties. DNA sequences used are obtained from the sequences used are obtained from the Virtual Library of Genetics.Virtual Library of Genetics.

AMELY & AMELXAMELY & AMELX

Amelogenin (tooth enamel protein)Amelogenin (tooth enamel protein) Gender SpecificGender Specific

Data – GenBankData – GenBank

DataData

CorrelagramCorrelagram

CorrelagramCorrelagram

AMELX AMELY

DNA SequencesDNA Sequences

HistogramHistogram

AMELX AMELY

Histogram of Amino AcidsHistogram of Amino Acids

AMELX AMELY

Why Bother?Why Bother?

►Synthetic lifeSynthetic life►Gender differencesGender differences

GoalsGoals

►Relative FrequencyRelative Frequency