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Reaction time correlations as a measure of eye-hand coordination. Heather Dean Pesaran Lab Center for Neural Science New York University. Interconnected brain areas may interact to plan and initiate coordinated movements. Getting at interacting circuits through behavior. - PowerPoint PPT Presentation
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Reaction time correlations as a measure of eye-hand coordination
Heather DeanPesaran Lab
Center for Neural ScienceNew York University
Interconnected brain areas may interact to plan and initiate
coordinated movements
• How are arm movements coordinated with eye movements?
Getting at interacting circuits through behavior
Correlated Reaction Times
100 200 300 400100
200
300
400
500
SaccadeRT (ms)
Reac
hRT
(ms)
100 200 300 400100
200
300
400
500
SaccadeRT (ms)
Reac
hRT
(ms)
AvgSaccRT = 219
AvgReachRT = 294
Std SRT: 37 ms
Std RRT: 41 ms
R = 0.55
There are several stages in movement preparation
SensoryInput
MovementPlanning
MovementExecution
Variability in RT is due to variability in the duration of these stages
Shared sensory processing attention/arousal
SensoryInput
SaccadePlanning
ReachPlanning
ReachExecution
SaccadeExecution
Shared sensory processingattention / arousal
ArousalAttention
Stimulus Onset Asynchrony Task
• Delay reach with respect to saccade up to 600 ms.
• This will disrupt coordination but not arousal.
Baseline
Hand GoSound
Stimulus Onset Asynchrony Task
Eye Go
Reward
SOA
Baseline
Hand GoSound
Eye Go
Reward
SOA
Baseline
Hand GoSound
Stimulus Onset Asynchrony Task
Eye Go
Reward
SOA
Baseline
Hand GoSound
Eye Go
Reward
SOA
Baseline
Hand GoSound
Stimulus Onset Asynchrony Task
Eye Go
Reward
SOA
Baseline
Hand GoSound
Eye Go
Reward
SOA
Baseline
Hand GoSound
Stimulus Onset Asynchrony Task
Eye Go
Reward
SOA
Baseline
Hand GoSound
Eye Go
Reward
SOA
Baseline
Hand GoSound
Stimulus Onset Asynchrony Task
Eye Go
Reward
SOA
Baseline
Hand GoSound
Eye Go
Reward
SOA
SOA is the time between movement go cues
0 600 Noreach
SOA durations
Prop
ortio
n of
tria
ls
Saccade
Reach
Go Sacc Start
Go
SOA
Reach StartReach RT
Saccade RT
Time
RT Correlations are not due to arousal
Correlations between SRT and RRT decrease with increasing time between movements.
0 200 400 600
0
0.2
0.4
SOA (ms)
0 200 400 600300
350
400
Reac
hRT
(ms)
0 200 400 600
150
200
Sacc
ade
RT (m
s)Co
rrel
atio
n
SOA (ms)
SOA (ms)
0 200 400 600
0
0.2
0.4
SOA (ms)
0 200 400 600300
350
400
Reac
hRT
(ms)
0 200 400 600
150
200
Sacc
ade
RT (m
s)Co
rrel
atio
n
SOA (ms)
SOA (ms)
0 200 400 600
0
0.2
0.4
SOA (ms)
Corr
elat
ion
AverageSaccadeR
Shared sensory processing attention/arousal
SensoryInput
SaccadePlanning
ReachPlanning
ReachExecution
SaccadeExecution
Shared sensory processingattention / arousal
ArousalAttention
Overlap in plans
Overlap is defined as the time between the start of the saccade and the cue to begin planning the reach.
Saccade
Reach
Go Sacc Start
Go
SOA
Reach StartReach RT
Saccade RT
Overlap
Time
-175 -75 25 125
0
0.2
0.4
0.6
-200-100 0 100300
350
400
-200-100 0 100
150
200
Overlap (ms)
Reac
hRT
(ms)
Sacc
ade
RT (m
s)Co
rrel
atio
n
175
Overlap (ms)
Overlap (ms)
RT correlations are nonzero when movement plans overlap
Correlations between SRT and RRT increase with increasing time of plan overlap.
Interacting Movement Planning
SensoryInput
SaccadePlanning
ReachPlanning
ReachExecution
SaccadeExecution
SensoryInput
ReachExecution
SaccadeExecution
MovementPlanning
SensoryInput
SaccadePlanning
ReachPlanning
ReachExecution
SaccadeExecution
InitialPlanning
Shared
SensoryInput
SaccadePlanning
ReachPlanning
ReachExecution
SaccadeExecution
RTCo
rrel
atio
nRT
Corr
elat
ion
RTCo
rrel
atio
nRT
Corr
elat
ion
SOA
End of shared initial planning
0
0
0
0End of saccade planning
SOA
SOA
SOA
SharedMovementPlanning
Shared Initial MovementPlanning
SeparateMovementPlanning
InteractingMovementPlanning
Accumulating Process Model
Saccade
Reach
Go Sacc Start
Go Reach StartReach RT
Saccade RT
movementthreshold
movementthreshold
initialactivity
initialactivity
Summary• For movement of two effectors, correlations
of RTs can show us how coordinated movements are.
• When hand and eye movements are made separately, RT correlations disappear.
• The degree of correlation seems to depend on the overlap between movement plans.
• Simultaneous multiple area recordings will let us identify neural mechanisms for coupling movement plans
Acknowledgements
Pesaran Lab
Eva Tsui
Bridget DiPrisco
Funding
Patterson Trust
Swartz Foundation
Burroughs-Wellcome Fund
Bijan Pesaran
Alfred P Sloan Foundation
