Reconstructed ancestor (LCA1)

BAp

norMribE pykF lpp ynhA sufS ynhC ynhD ydiC

ribE ydiCmesJ rnfA yb1688tyrS

99 100 98 109 110 108

BBp ribE ydiCmesJ rnfA yb1688tyrS

95 96 94 109 110 108

norM

pykF lpp ynhA sufS ynhCdeleted fragment in BAp ynhDnorM

pykF lpp ynhA sufS ynhC ynhDdeleted fragment in ancestor of Buchnera

93

Bfl ribE ydiC

342 336337

pykFdeleted fragment in ancestor of Buchnera and Bfl (LCA2)

lpp ynhA sufS ynhC ynhD

340 341 339 338

ynhE

ynhE

ynhE

ynhE

335

step 1

step 2

step 3