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www.pharmacyexam.com Krisman
REFERENCE GUIDEFOR FOREIGNPHARMACY
LICENSING EXAM(Questions and Answers )
Manan H. Shroff
2014-2015
www.pharmacyexam.com Krisman
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REFERENCE GUIDE FORFOREIGN PHARMACY
LICENSING EXAM(Questions and Answers )
DEDICATED
T
O
KRISHNA
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This reference guide is not intended as a substitute for the advice of a physician. Studentsor readers must consult their physician about any existing problem. Do not use any informationin this reference guide for any kind of self-treatment. Do not administer any dose of mentioneddrugs in this reference guide without consulting your physician. This is only a review guide forpreparation for the Foreign Pharmacy Licensing board exam.
The author of this reference guide is not responsible for any kind of misinterpreted, incorrect ormisleading information or any typographical errors in this guide. Any doubtful or questionableanswers should be checked in other available reference sources.
All rights reserved.
No part of this guide may be reproduced or transmitted in any form or by any means, electroni-cally photocopyed, recorded or otherwise , without prior written permission of the publisher.
RXEXAM is a registered trademark of Pharmacy Exam of Krishna Publication Inc. Anyunauthorized use of this trademark will be considered a violation of law.
NAPLEX and FPGEE are federally registered trademarks owned by the National Associa-tion of Boards of Pharmacy (NABP) and this reference guide is in no way authorized or spon-sored by NABP.
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REFERENCE GUIDEFOR FOREIGNPHARMACY
LICENSING EXAM(Questions and Answers )
Manan H. Shroff
2014-2015
PREFACE
Reference Guide For Foreign Pharmacy Licensing Exam Questions and Answers -
2014-2015 Edition is specifically written for students preparing for the FPGEEExam.
It has approximately 1000 FPGEETYPE questions with answers and complete explanations.
The FPGEEexam puts more emphasis on pharmacy management, statistics, immunology,
pharmacology, kinetics and biopharmaceutics, therefore an effort was made to include all of
these topics in a review guide. To prepare for pharmacology, I would highly recommend that you
take advantage of the Reference Guide For Pharmacy Licensing Exam-Theory.
Our preparation guide covers all the important topics you need to be familiar with to pass the
FPGEE. I would recommend that you to go through the FPGEEreview guide sample
questions provided by the NABP (you will get one when your approval from the
FPGEEarrives) to evaluate the importance of our review materials.
Each answer is explained thoroughly to refresh your memory on specific topics. Please do
not go through only the questions and answers. Try to understand and learn the answers
explanations. It is the best way to get the most out of this review guide.
I hope my efforts will help you to pass your key exam. I wish you the very best of luck, and
any questions or comments are always welcome.
Good Luck,
Manan Shroff
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TABLE OF CONTENTS
SECTION-I
QUESTIONS 7
SECTION-II
ANSWERS 121
SECTION-III
TABLES 243
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1 Benzyl alcohol is classified as:
a. Emulsifying agentb. Preservativec. Diluentd. Suspending agent
2. Cold cream is an example of:
a. Suspensionb. O/W emulsionc. W/O emulsiond. O/W/O emulsion
3. Egg yolk or egg white is used as:
a. Emulsifying agentb. Suspending agentc. Binderd. Preservative
4. The transfer of a drug from high con-centrated areas to low concentrated areas isgenerally defined as:
a. Infusionb. Levigationc. Dif fusiond. Dissolution
5. Which of the following is the mostsuitable route for administration of insulin ?
a. IMb. SCc. IVd. IV bolus
6. Noyes Whitney equation is helpful topredict the rate of:
a. Drug diffusionb. Drug dissolution
c. Drug degradationd. Drug oxidation
7. Polymorphism is generally defined asa:
a. Substance that may exist in more thanone crystalline form.
b. Substance that may exist only in meta-stable form.
c. Substance that has different viscositytime to time.
d. Substance that reduces interfacial ten-sion.
8. The minimum concentration of a drugat the receptor site to initiate pharmacologi-cal action is defined as:
a. T maxb. MECc. MTCd. Cmax
9. The area under curve gives useful in-formation about :
a. The amount of drug systematically ab-sorbed.
b. The time to reach peak concentration.
c. The time to reach minimum toxicconcentration.
d. The concentration at which pharma-cological actions of drug would beinitiated.
10. Which of the following is the majorplasma protein involved in drug binding?
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a. Globulinb. Creatininec. Albumind. Glycoprotein
11. Which of the following equations maybe useful to find out the plasma concentrationof a drug ?
a. Vd x P = Cpb. P x Cp = Vdc. Vd = P/Cpd. Vd = Cp/P
12. The initial dose of a drug through IVbolus to achieve desirable plasma concentra-tion at once is known as:
a. Loading doseb. Maintenance dosec. Replacement dosed. Degradation dose
13. Which of the following is/are usefulto measure glomerular filtration rate?
I. CreatinineII. InulinIII. Albumin
a. I onlyb. I and II onlyc. II and III onlyd. All
14. The rapid degradation of a drug byliver enzymes in a liver is defined as:
a. Third pass effect of metabolismb. First pass effect of metabolismc. Rapid degradationd. Liver elimination
15. The normal renal creatinine clearancevalue lies between:
a. 200 to 300 ml/minb. 80 to 120 ml/minc. 30 to 60 ml/mind. 10 to 20 ml/min
16. Which of the following is an exampleof an oligosaccharide?
a. Glucoseb. Sucrosec. Starchd. Glycogen
17. Which pyrimidine base is found only inRNA?
a. Cytosineb. Thyminec. Uracild. Adenine
18. Heparin is classified as a(n):
a. Heteropolysacharideb. Oligosaccharidec. Homopolysacharided. Monosaccharide
19. Ribonucleic acid exists in all of thefollowing forms EXCEPT :
a. r RNAb. m RNAc. q RNAd. t RNA
20. Which of the following structures is ahost for Krebs cycle ?
a. Mitochondriab. Golgi bodies
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c. Cytoplasmic membraned. Ribosome
21. The synthesis of glucose from sourcesother than carbohydrates is generally knownas:
a. Glycolysisb. Gluconeogenesisc. Glycogenolysisd. Glucogenesis
22. Which of the following amino acidsshould be considered an essential aminoacid(s) for the body ?
I. PhenylalanineII. LeucineIII. Tryptophan
a. I onlyb. I and II onlyc. II and III onlyd. All
23. Which of the following enzymes ca-talyses the coupling of two molecules ofnucleotides to form DNA ?
a. Transferaseb. Ligasec. Isomerased. Aldehyde dehydrogenase
24. A nucleotide is a building block of:
a. Sphingomideb. Nucleic acidc. Amino acidd. Starch
25. Which of the following cells are in-volved with immune responses of the body?
I. B lymphocytesII. T lymphocytesIII. Neutrophils
a. I onlyb. I and II onlyc. II and III onlyd. All
26. Which of the following immunoglo-bulin levels are elevated during asthma ?
a. IgMb. IgDc. IgEd. IgA
27 All of the following tests are requiredto check sensitivity of class A weighing pre-scription balance EXCEPT :
a. Arm ratio testb. Rider graduated beam testc. Shift testd. U test
28. The ratio of the mass of an objectmeasured in a vacuum at specific tempera-ture to volume (in ml) of an object at the sametemperature is defined as:
a. Absolute densityb. Specific gravityc. Relative densityd. Apparent density
29. The mean blood pressure of Mr. Hamis:
01/01/00 80 mm hg 04/04/00 90 mm hg01/02/00 82 mm hg 01/05/00 85 mm hg01/03/00 81.5 mm hg 01/06/00 83 mm hg
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a. 81.5b. 85.6c. 83.58d. 84.20
30. The deviation of data from its mean isgenerally described by:
a. The averageb. The standard deviationc. The precisiond. The accuracy
31. The reproducibility of results of anumber of experiments is generally known as:
a. Precisionb. Biasc. Accuracyd. Closelessness
32. If the value of p = 0.6 in binomial dis-tribution, what is the probability of failure ?
a. 0.2b. 0.4c. 0.3d. 1.0
33. The error is generally consideredsignificant at:
a. 1%b. 3%c. 5%d. 10%
34. When the hypothetical value of a pa-rameter is the same as the observed value of aparameter, the error should be considered:
a. Alfa-errorb. Beta-errorc. Gema-errord. Infinitive
35. Find out the degrees of freedom in aChi-square test in a 2x2 contingency table (as-sume tests are independent).
a. 1b. 2c. 3d. 4
36 The F distribution generally compares:
a. Two meansb. Two variancesc. Three meansd. Three variances
37. Which of the following elements hasthe highest electronegativity?
a. Clb. Fc. Brd. I
38. Which of the following molecules hasthe largest dipole movement?
CH3 CI
C C
CH3 Cl
FIGURE - I
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CH3 H
C C
H CH3
FIGUR