REGION 5 RAC2 · BLL blood lead level FS feasibility study GI gastrointestinal ... ppm parts per million PRG preliminary remediation goal QAPP quality assurance project plan

..

REGION 5 RAC2

REMEDIAL ACTIOr✓ CONTRACT FOR

Remedial, Enforcement Oversight, and

Non-Time Critical Removal Activities at Sites of Release

or Threatened Release of Hazardous Substances in Region 5

BIOAVAILABILITY STUDY REPORT

JACOBSVILLE NEIGHBORHOOD SOIL

CONTAMINATION SITE Evansville, Indiana

Remedial Investigation/Feasibility Study

WA No. 015-RICO-BSlZ/Contract No. EP-SS-06-01

January 2008

U.S. Environmental Protection Agency

CH2M HILL

Ecology and Environment, Inc. Environmental Design International, Inc. Teska Associates, Inc.

928468

BIOAVAILABILITY STUDY REPORT

JACOBSVILLE NEIGHBORHOOD SOIL CONTAMINATION SITEEvansville, Indiana

Remedial Investigation / Feasibility Study

WA No. 015-RICO-B51Z / Contract No. EP-S5-06-01

January 2008

Contents

Acronyms and Abbreviations v1 Introduction 1-1

1.1 Site Description 1-11.2 Site History 1-11.3 Previous Investigations 1-2

2 Purpose 2-13 Field Activities 3-14 Analytical Data 4-1

4.1 Analytical Method 4-14.2 Analytical Results 4-14.3 Data Evaluation 4-2

4.3.1 Data Usability 4-24.3.2 Preliminary Remediation Goals 4-2

5 Summary 5-16 References 6-1

Appendixes

A Data Quality EvaluationB IUEBK Input/Output Models

Tables

1 Summary of Lead and Bioavailable Lead Detected in Soil2 Summary of In Vitro Bioaccessibility Results from the Jacobsville Site3 Results of In Vitro Bioaccessibility Presented in USEPA, 2007

Figures

1 Site Map2 Soil Sample Locations3 Soil Lead Concentrations4 Lead Bioavailability5 Probability Distribution of BLLs for a Range of Lead Concentrations in Soil:

Minimum Scenario6 Probability Distribution of BLLs for a Range of Lead Concentrations in Soil: Average

Scenario7 Probability Distribution of BLLs for a Range of Lead Concentrations in Soil:

Maximum Scenario

MKE 080170001

Acronyms and Abbreviations

ABA absolute bioavailabilitybgs below ground surfaceBLL blood lead levelFS feasibility studyGI gastrointestinalHHRA human health risk assessmentIDEM Indiana Department of Environmental ManagementIEUBK Integrated Exposure Uptake BiokineticIVBA in vitro bioavailability analysisJNSC Jacobsville Neighborhood Soil Contaminationug/dL micrograms per deciliterug/kg micrograms per kilogramNIST National Institute of Standards and TechnologyOU operable unitppm parts per millionPRG preliminary remediation goalQAPP quality assurance project planRBA relative bioavailabilityRI remedial investigationSD standard deviationSRM Standard Reference MaterialIDS Total Diet StudyUSEPA United States Environmental Protection Agency

MKE 080170001

SECTION 1

Introduction

This bioavailability study report was prepared for the U.S. Environmental ProtectionAgency (USEPA) as part of the remedial investigation (RI)/feasibility study (FS) inaccordance with the statement of work for Work Assignment No. 015-RICO-B51Z, ContractNo. EP-S5-06-01. This report presents the sampling data, field procedures, usability of thedata, role of bioavailability in risk-based remedial goal calculations, a discussion of thestudy's consistency with similar studies compiled by USEPA, and the range of site-specificpreliminary remediation goals (PRGs).

1.1 Site DescriptionThe Jacobsville Neighborhood Soil Contamination (JNSC) site is located in Evansville,Indiana, in Vanderburgh County (Figure 1). In 2000, the Indiana Department ofEnvironmental Management (IDEM) sampled residential soils using portable X-rayfluorescence spectrometers and found elevated concentrations of lead. IDEM originallydefined the site as bounded to the west by Edgar Street, to the south by Lloyd Expressway,to the east by Heidelbach Street, and to the north by Iowa Street (IDEM site boundary).Recent USEPA investigations have indicated that the site may encompass a larger area.

The current sampling boundary encompasses an urban residential/commercial area ofabout 11 square miles that lies on flat terrain (referred to as the JNSC sampling boundary).USEPA has identified northern (Operable Unit [OU] Northern Sampling Area) and southern(OU Southern Sampling Area) sampling areas that generally lie within the JNSC samplingboundary. This report focuses on an area slightly larger than the IDEM site boundary,known as the FS focus area, or OU1 (Figure 1). The FS focus area encompasses 141 acres and508 residential properties. USEPA developed the focus area based on lead concentrationsobserved during the RI phase.

1.2 Site HistoryIDEM identified four former facilities that may have contributed to contamination at thesite: the Blount Plow Works (operated from the 1880s to about the 1940s), Advance StoveWorks (operated from the turn of the century to about the 1950s), Newton-Kelsay (operatedfrom the turn of the century to the 1950s), and Sharpes Shot Works (operated from 1878 toan unknown date) (Figure 2). The facilities were located within the urban residential area.Current conditions at these facilities are as follows:

• The Blount Plow Works building has been demolished. A supermarket, Buehler's IGA,and an asphalt parking lot are now present at the site.

• A one-story brick storage building with a gravel parking lot occupies part of the formerNewton-Kelsay property. A McDonald's restaurant occupies the eastern part of theproperty.

MKE 080170001

BIOAVAILABIUTY STUDY REPORT

• The former Sharpes Shot Works and the Advance Stove Works facilities are now gravelparking lots. A chain-linked fence encompasses the two sites.

In addition to the four facilities described above, Evans- ille Plating Works also may havecontributed to the contamination. The company, which began operations in 1897, platedzinc, brass, nickel, copper, iron black (iron oxide), cadmium, and chromium for individualsand industry. Evansville Plating Works is located at 100 West Indiana Street, south of theJacobsville neighborhood (Figure 2). The 1-acre site formerly was occupied by a large,dilapidated, one-story building. The building was demolished, and the lot is now empty(USEPA 2005b). The site also contains a parking lot and a small grassy field. Land usesurrounding the site is predominantly residential with small and light industrial businessesnearby.

1.3 Previous InvestigationsThe following site investigations were performed at the JNSC site:

• Evansville Plating Works site investigation (USEPA 1990)• Integrated assessment for JNSC site (IDEM 2002)• Site assessment for Evansville Plating Works (Weston Solutions [for USEPA] 2003)• Site characterization 1 (USEPA 2005c)• Site characterization 2 (USEPA 2005d)• Site characterization 3 (USEPA 2005b)• RI (CH2M HILL 2006)

12 MKE 080170001

OU2 NORTHERN AREA

JACOBSVILLE NEIGHBORHOOD SOILCONTAMINATION SAMPLING BOUNDARY

i IDEM SITE BOUNDARY f?:^P.;\'

SOUTHERN AREA

2,000 4,000Feet

SCALE IS APPROXIMATE

\\LOKUPROJECTS\RDDGIS\JACOBSVILLE\MXDS\SSP_ADD\FIG_1 _SITE_MAP^SSP.MXD 9/4/200709:53:58

FIGURE 1SITE MAPJACOBSVILLE NEIGHBORHOODSOIL CONTAMINATION SITEEVANSVILLE, INDIANA

CH2MHILL

Blount Plow Works

Advance Stove Works

Newton-Kelsay

LEGEND

O SOIL SAMPLE LOCATION

HISTORICAL SITES

RESIDENTIAL PARCEL

FEASIBILITY STUDY FOCUS AREA

FIGURE 2SOIL SAMPLE LOCATIONSJACOBSVILLE NEIGHBORHOOD SOIL CONTAMINATION SITE

, INDIANA

CH2MHILL —\\LOKI PRQJECTS\RDDGISUACC8SVILLBMXDS\REPORT\FIG_2_SAMP_LOC.MXD FIG_2__SAMP_LOC.PDF 11/4/2007 2323:53

SECTION 2

Purpose

Bioavailability is the fraction of lead in the soil matrix that can be absorbed into thebloodstream by a specific exposure pathway. Some constituents are absorbed almostcompletely (100 percent bioavailability) when ingested in their pure, soluble form. Othersmay pass through the body largely unabsorbed. Oral bioavailability of soil-bound lead isinfluenced by the rate at which it dissociates or solubilizes from the soil matrix in thegastrointestinal (GI) tract. Soil-bound lead is usually absorbed by the GI tract to a lesserdegree than when in a pure, soluble form. This reduced absorption results from the affinitybetween the lead and soil matrix, the low solubility of the form of lead associated with thesoil, or both. Thus, the bioavailability of lead from soil is expected to be lower when tightlybound within the soil matrix and/or in a form that is insoluble in the GI tract underphysiological conditions. This study was undertaken to evaluate the site-specificbioavailability of lead present in soil samples at the site. The bioavailability data were usedto develop a range of site-specific PRGs (a default PRG was developed as part of the FS).

The human health risk assessment (HHRA) provided in the RI report (CH2M HILL 2006)evaluated potential risks from lead exposures using default lead bioavailability valuesembedded in the Integrated Exposure Uptake Biokinetic (IEUBK) model. The site-specificbioavailability data generated as part of this study were used in place of the default leadbioavailability values in the model to generate a more site-specific evaluation of leadexposures.

MKE 080170001 2-1

SECTION 3

Field Activities

The proposed sampling locations were residential properties within the FS focus area thatwere sampled and analyzed for lead in soil during the RI. The sample locations andrespective depth intervals were chosen to provide a range of concentrations for thebioavailability study. Some of the proposed locations were unavailable for sampling, so anearby property was sampled upon obtaining access (Figure 2).

A five-point composite of soil was collected at each of the 26 residential soil samplelocations. The five-point composite was collected in a manner that is representative of theresidential property as a whole (for example, composites include soil from the front, back,and side yards of each property, where applicable). The soil samples were sieved by thelaboratory, and the material less than 250 microns was used for analysis. Samples werecollected with a trowel or hand auger and composited in scalable disposable plastic bags.The composite soil samples were collected at the 0- to 6-inch interval, the 6- to 12-inchinterval, or both, and submitted to an offsite laboratory for analysis of total lead andbioavailable lead.

During the field activities, 31 samples were collected (Table 1). Of these, 19 samples werechosen to be analyzed for lead bioavailability based on the concentration of total lead. Arange of concentrations was selected for bioavailability analysis. Thirteen samples werecollected from the 0- to 6-inch depth interval and six from the 6- to 12-inch depth interval.Soil samples were collected from both the 0- to 6-inch and 6- to 12-inch intervals at two ofthese residential properties (Figure 3).

MKE 080170001

TABLE 1

Summary of Lead and Bioavailable Lead Detected in SoilJacobsville Neighborhood Soil Contamination Site

Analyte

Lead

Bioavailable Lead

Lead

Bioavailable Lead

Lead

Bioavailable Lead

Address:Sample Name:

Sample ID:Interval:

Units Date:

mg/kg

%


Sample ID:Interval:

Date:

mg/kg

%


Sample ID:Interval:

Date:

mg/kg

%

JNS-SB15000/0607CJ46-300-6 inches9/11/2007

615.88

75

JNS-SB1390070607CJ46-220-6 inches9/11/2007

463.89

NA

JNS-SB14900/0607CJ46-290-6 inches9/11/2007

739.54

89

JNS-SB12400/0607CJ46-09B

0-6 Inches9/1 0/2007

1228.79

80

JNS-SB13900/06R07CJ46-210-6 inches9/11/2007

415.15

NA

JNS-SB14800/0607CJ46-280-6 inches9/11/2007

378.56

NA

JNS-SB1 3700/0607CJ46-130-6 inches9/10/2007

815.39

87

JNS-SB14306/1207CJ46-18

6-12 inches9/11/2007

191.77

NA

JNS-SB14800/06R07CJ46-270-6 inches9/11/2007

319.66

NA

JNS-SB1 3606/12

07CJ46-126-12 inches

9/10/2007

361.22

82

JNS-SB14200/0607CJ46-190-6 inches9/11/2007

390.59

NA

JNS-SB11606/1207CJ46-01

6-12 inches9/6/2007

224.38

77

JNS-SB14100/0607CJ46-200-6 inches9/11/2007

787.74

85

JNS-SB1 2800/0607CJ46-050-6 inches

9/6/2007

482.92

75

JNS-SB14700/0607CJ46-260-6 inches9/11/2007

797.65

89

JNS-SB13800/0607CJ46-140-6 inches9fl 0/2007

643.66

76

JNS-SB12800/06R07CJ46-060-6 inches

9/6/2007

487.19

80

JNS-SB14600/0607CJ46-250-6 inches9/11/2007

464.84

NA

JNS-SB1 3806/1207CJ46-15

6-12 inches9/10/2007

385.37

71

JNS-SB1340Q/0607CJ46-100-6 inches9/10/2007

371.02

NA

JNS-SB13100/0607CJ46-080-6 inches9/6/2007

859.76

81

JNS-SB13006/1207CJ46-07

6-12 inches9/6/2007

695.51

73

JNS-SB12300/0607CJ46-030-6 inches9/6/2007

336.78

NA

JNS-SB14400/0607CJ46-170-6 inches9/11/2007

1249.19

92

JNS-SB1 2200/0607CJ46-020-6 inches9/6/2007

988.69

84

JNS-SB12500/0607CJ46-09A0-6 inches9/6/2007

834.01

73

JNS-SB1 4500/0607CJ46-160-6 inches9/11/2007

314.49NA

JNS-SB1 4000/0607CJ46-230-6 inches9/11/2007

360.04

NA

JNS-SB12506/1207CJ46-04

6-12 inches9/6/2007

648.48

62

JNS-SB15106/12

07CJ46-316-12 inches

9/11/2007

458.90

83

JNS-SB13500/0607CJ46-110-6 inches9/10/2007

603.56

81

Note:

Results that indicate a detection are shown in bold.

Results that indicate detections above the screening value are shaded.

NA = Sample was not analyzed for results.

Sharpes Shot Works |~~

SB-151458.90 (6 -12)

SB-ipl*®-•76(0^6]

SB-116224.38 (6-^J

SB-135

v SB-148378.56 (0 -

615.88(0-6)

SB-146 t464.84 (0 - 6)

SB-149| 739.54(0-6) 797.65(0-6)

\_SB-141

SB-124JI >SB-1228 79 I&-6V ' 643.66 (<t - 6)

385.37 iy*2)

* s-

05*13437102(0-6)*

7^1 i i. :.01(0-6).48 (6 f 12)

: SB-1425^(0-6)

482.92(0-6)

S ; 88-130695.51 (6M12)

Newton-KelsayLEGEND

SOIL SAMPLE LOCATION

HISTORICAL SITES

| | RESIDENTIAL PARCEL SCALE IS APPROXIMATE

FEASIBILITY STUDY FOCUS AREA

SB-140360.04 (0 - 6)SOIL CONCENTRATION (mg/kg)

SAMPLE DEPTH (Inches below ground surface)

FIGURE 3SOIL LEAD CONCENTRATIONSJACOBSVILLE NEIGHBORHOOD SOIL CONTAMINATION SITEEVANSVILLE, INDIANA

CH2MHILL

\\LOKl\PRQJEC7S\RDDGISVJACOBSVILLBMXDS\REPORT\HG_3_LEAD_CONC.MXD FIG_3_LEAD_CONC.PDF 11/13G00722:33fl1

SECTION 4

Analytical Data

4.1 Analytical MethodMany animal studies have been conducted experimentally to determine oral bioavailabilityof individual metals, particularly lead. Several researchers have developed in vitro tests tomeasure the fraction of a chemical solubilized from a soil sample under simulated GIconditions. The analytical method for in vitro bioavailability analysis (IVBA) selected forthis study is discussed in depth in the site-specific plans-addendum (CH2M HILL 2007b).

The IVBA tests consist of an aqueous fluid into which the contaminant is introduced. Thesolution then solubilizes the media under simulated gastric conditions. Once the procedureis complete, the solution is analyzed for the lead concentration. The mass of lead found inthe filtered extract is compared to the mass introduced into the test. The fraction liberatedinto the aqueous phase is defined as the bioaccessible fraction in that media.

4.2 Analytical ResultsThe total lead analysis was conducted prior to the IVBA analysis to verify that the samplecontained sufficient lead concentrations to achieve the objectives of the study. Nineteen soilsamples (and one field duplicate) were collected from OU1 for IVBA analysis. A descriptionof the sampling effort and specific sampling locations is provided in Section 3. Table 2summarizes the IVBA data collected from the site. Although the difference is minimal (lessthan 10 percent), the average IVBA of surface soil (0 to 6 inches below ground surface [bgs])was greater than that of subsurface soil (6 to 12 inches bgs). However, because the ranges ofIVBAs from surface and subsurface soil overlap and a significant difference does not appearto exist, the IVBA in the pooled dataset from surface soil and subsurface soil samples ("totalsoil" in 3) was used for calculating a range of site-specific PRGs. Individual sample results areprovided in Table 1.

TABLE 2Summary of In Vitro Bioaccessibility ResultsJacobsville Neighborhood Soil Contamination Site

Matrix

Total soil

Surface soil (0 to 6 inches bgs)

Subsurface soil (6 to 12 inches bgs)

Sample SizeIN]

19

13

6

Range

62.0 - 92.0

73.0 - 92.0

62.0-83.0

IVBA [%]

Mean

79.7

82.1

74.7

SD

7.4

6.2

7.8

bgs - below ground surfaceIVGA - in vitro bioavailability analysisSD - standard deviation

MKE 080170001 4-1

BIOAVAILABIUTY STUDY REPORT

4.3 Data Evaluation

4.3.1 Data UsabilityAppendix A contains an evaluation of the \Jata usability. The completeness objectives weremet for the method/analyte combinations. No data were qualified because of low-levelblank contamination. The precision and accuracy of the data, as measured by field andlaboratory quality control indicators, demonstrate that the Jacobsville quality assuranceproject plan (QAPP) goals were met.

Consistency with Results from Other SitesWhen USEPA developed the methodology to estimate relative bioavailability of lead in soiland soil-like materials using in vivo and in vitro procedures, data were evaluated from17 samples representing eight different sites and two soil-like materials (paint flakes mixedwith clean soil and finely ground native galena mixed with clean soil) (USEPA 2007). Table 3summarizes the mean and standard deviation of IVBA data from these sites, as provided inUSEPA's study. The observed IVBA from the JNSC site is consistent with the range of datapreviously reported by USEPA (USEPA 2007), being in the upper end of the IVBAs reported.

4.3.2 Preliminary Remediation GoalsThis section summarizes the methodology used to apply the site-specific IVBA data to thedevelopment of a site-specific PRG for lead in soil at the JNSC site. USEPA guidance entitledEstimation of Relative Bioavailability of Lead in Soil and Soil-like Materials Using In Vivo and InVitro Methods (USEPA 2007) was used. The site-specific PRGs protective for children (0 to6 years old) at residential properties were calculated using the site-specific IVBA data asinput in USEPA's IEUBK model (USEPA 2005).

Bioavailability of lead in site soil can be expressed either in absolute terms (absolutebioavailability [ABA]) or in relative terms (relative bioavailability [RBA]). ABA is the ratioof the amount of lead absorbed in the body compared to the amount ingested. This ratioalso is referred to as the oral absorption fraction:

ABA = (Absorbed Dose) / (Ingested Dose)

RBA is the ratio of the ABA of lead present in site soil to the ABA of lead in a referencematerial:

RBA = (ABAsite soil) I (ABAreference material)

The reference material is usually a compound that is expected to completely dissolve wheningested, such as lead acetate (USEPA 2007).

The site-specific PRGs were developed for the JNSC site soil using a three-step process:

1. Estimation of in vivo RBAs from site-specific IVBA data obtained from the site

2. Estimation of corresponding site-specific ABAs based on site-specific RBAs andbioavailability of lead from water

3. Calculation of a revised site-specific PRG using the MJBK model and the site-specific AB \s

4.2 MKE 080170001

4-ANALYTICALDATA

TABLESResults of In Vitro Bioaccessibility Presented in USEPA2007Jacobsville Neighborhood Soil Contamination Site

Site Sample DesignationIVBA(%) (Meant

Standard Deviation)

California Gulch NPL Site, Leadville,Colorado

Jasper County, Missouri Superfund Site

Kennecott NPL Site, Salt Lake City, Utah

Midvale Slag NPL Site, Midvale, Utah

Murray Smelter Superfund Site, MurrayCity, Utah

New Jersey Zinc NPL Site, Palmerton,Pennsylvania

Silver Bow Creek/Butte Area NPL Site,Butte, Montana

Smuggler Mountain NPL Site, Aspen,Colorado

Iron/Manganese Lead Oxide 87.2 ± 0.5

Residential Soil 65.1 ±1.5

California Gulch Oregon Gulch Tailings 11.2 ± 0.9

Arkansas Valley Smelter Slag 9.4 ± 1.6

High Lead Mill 85.3 ± 0.2

Low Lead Yard 79.0 ± 5.6

High Lead Smelter 69.3 ± 5.5

Creek Residential 47.0 ± 1.2

Creek Channel Soil 37.8 ± 0.7

Midvale Slag 17.4 ±0.9

Smelter Soil 74.7 ± 6.8

Smelter Slag 64.3 ± 7.3

Location 4 69.7 ± 2.7

Location 2 63.6 ± 0.4

Butte Soil 22.3 + 0.6

Aspen Residential 71.4 ± 2.0

Aspen Berm 64.9 ± 1.6

NIST Painta 72.5 ± 2.0

Galena-enriched Soil California b 4.5 ± 1.2

a A mixture of National Institute of Standards and Technology (NIST) Standard Reference Material (SRM) 2589composed of paint collected from the interior surface of houses in the U.S. and low lead soil (< 50 ppm)collected in Leadville, Colorado.b A mixture of galena and low lead soil (< 50 ppm) collected in Leadville, Colorado.

Step 1—Estimation of Relative In Vivo Bioavailability

In order for an IVBA test system to be useful in predicting the in vivo RBA of a test material,it is necessary to establish empirically that a strong correlation exists between the in vivoand the in vitro results across many different samples. Based on the studies summarized inTable 3, USEPA established the following empirical linear regression model between RBAsin vitro and in vivo (juvenile swine) procedures (2007):

RBA = 0.878 x IVBA - 0.028

Using this equation, the in vivo RBA of lead in site soil was estimated based on thesite-specific IVBAs measured in soil samples collected from the site.

MKE 080170001 4-3

BIOAVAIUBIUTY STUDY REPORT

A range of site-specific RBAs corresponding to the rrunimurn, average, and maximumsite-specific FVBA was calculated (Appendix B). As previously noted, the average IVBA inthe pooled dataset from surface soil and subsurface soil samples was used for thecalculation because the ranges of FVBAs from surface and subs'irface soils overlap and asignificant difference does not appear to exist.

The calculated sample-specific RBAs range from 51.6 to 78.0 percent with an average RBA of67.2 percent. The RBA based on the average IVBA is approximately 7 percent higher thanUSEPA's default RBA of 60 percent used in the IEUBK model; however, both the site-specific and the default RBA are within the range of RBAs calculated based on data fromother sites (Table 3).

Step 2—Absolute Bioavailability

Based on available information in literature on lead absorption in humans, USEPA estimatesthe absolute bioavailability of lead from water and the diet is usually about 50 percent inchildren (USEPA 1994). Thus, when a reliable site-specific RBA value for soil is available, itmay be used to estimate a site-specific absolute bioavailability in that soil, as follows:

ABA = 50% • RBA .,soil soil

Where:

ii = ABA of lead in site soil ingested by a childti = site-specific RBA of lead

The calculated ABAsoa ranges from 25.8 to 39.0 percent with an average ABAsou of33.6 percent. The calculated ABAsou based on the average RBA is approximately 4 percentgreater than USEPA's default ABA of 30 percent used in the IEUBK model; however, boththe site-specific and the default ABA are within the range of ABAs calculated based on datafrom other sites (Table 3).

Step 3— Revised PRGThe estimated site-specific ABAsou was entered into the IEUBK model (IEUBKwin32 LeadModel Version 1.0 Build 264; USEPA 2005a) to calculate a PRG for site soil corresponding tothe USEPA target level of 95 percent of the population with a blood lead level (BLL) below10 micrograms per deciliter (ng/dL). Because children are more toxicologically sensitive tolead than adults, they were considered for this assessment.

The updated dietary lead intake estimates generated from the U.S. Food and DrugAdministration Total Diet Study (TDS; FDA 2001) replaced the IEUBK model default dietarylead intake estimates. In addition, the site-specific ABAsou replaced the IEUBK model defaultsoil and dust GI bioavailability values. The remaining default input values were leftunchanged in the IEUBK model. The default assumptions in the model include concurrentexposure to lead in other media (besides soil), such as:

• A constant ambient air concentration of 0.1 micrograms of lead per cubic meter(Hg lead/m3)

4.4 MKE 080170001

4-ANALYTICAL DATA

• A constant indoor air concentration of lead that is 30 percent of the outdoor airconcentration

• A diet (food) concentration of lead that varies based on age, in accordance with the TDS(FDA 2001)

• A constant drinking water concentration of 4 jig lead per liter

• A constant indoor dust concentration of lead that is 70 percent of the outdoor soilconcentration

The "multiple runs" option was used to obtain percentages of the population with a BLLabove 10 ng/dL for a range of lead concentrations using the minimum, maximum, andaverage site-specific ABAsou (Figure 4). Figures 5, 6, and 7 present the probabilitydistribution of BLLs for a range of lead concentrations in soil (the concentration ranges werenarrowed after several model runs) for the minimum, average, and maximum scenarios,respectively. Based on the model output, the lead concentrations in soil corresponding to thetarget BLL range from 306 milligrams per kilogram (mg/kg; based on the maximum IVBA)to 467 mg/kg (based on the minimum IVBA), with 357 mg/kg as the average. Appendix Bcontains the input values and output of the IEUBK model.

Uncertainties in the PRGThe empirical linear regression model between in vivo and in vitro procedures establishedby USEPA (2007) was used to calculate RBAs and subsequently the range of site-specificPRGs. The linear regression model was based on soil samples from eight sites and two soil-like materials. Because the equation used to calculate RBAs is based on limited soil samplesand the RBA of lead in soil largely depends on the mineral and physical nature of the metal-bearing grains in soil, the site-specific PRG range may be over- or underestimated.

Studies in humans indicate that lead absorption is reduced by the presence of food in thestomach (USEPA1996). Eating and other behavioral factors play a significant role in the oralabsorption fraction of lead. Therefore, the assumed ABAsoiubie (50 percent) that was used tocalculate the range of PRGs may overestimate absorption and have resulted in overlyconservative PRGs.

MKE 080170001 4-5

Sharpes Shot Works]

SB-151

83%(6-12flSB-150

SB-147 ,75% (0-6)

SB-149

89% (0-6)\_>B-141

85% (0-6)

SB-124 S O SB-138 I

80% «*-€> ™%$^18-128

»• 75% (0-6)80% (0-6)

SB-137

=f7%(0-6)

:Advance Stove Works

EvansvillePlating Works

Newton-Kelsay

LEGEND

O SOIL SAMPLE LOCATION

HISTORICAL SITES

RESIDENTIAL PARCEL

FEASIBILITY STUDY FOCUS AREA FIGURE 4LEAD BIOAVAILABILITYSB-135

81% (0-6] JACOBSVILLE NEIGHBORHOOD SOIL CONTAMINATION SITEPERCENT BIOAVAILABLE LEACEVANSVILLE, INDIANASAMPLE DEPTH (Inches below ground surface]

CH2MHILL\\LOKI\PROJECTSWDDGIS\JACC8SVILLBMXDSWEPORT\FIG4 BIO LEAD.MXD RG 4 BIO LEAD.PDF 11/13/200722:43:19

Prob. Distribution for Multiple Runs (%)100r

9 12 15 18 21 24 27 30

Blood Pb Cone (ug/dL)

Cutoff =10.000 ug/dlGSD= 1.600

Run#1234567

% Above4.9384.9664.9945.0235.0515.0795.108

Media Choice = SOILAge Range = 0 to 84 monthsRun Mode = ResearchComment = Minimum IVBA (62%)

Concentration465.000465.833466.667467.500468.333469.167470.000

FIGURE 5PROBABILITY DISTRIBUTIONOF BLLs FOR A RANGE OFLEAD CONCENTRATIONS INSOIL: MINIMUM SCENARIOJACOBSVILLE NEIGHBORHOODSOIL CONTAMINATION SITEEVANSVILLE, INDIANA

Wercules\groups\PuWicalions\EE&SyNSC_Bioavailabilily_Report_ES112007025MKE CHZIVIHILL^


9 12 15 18 21 24 27 30



Run*1234567

% Above4.9154.9524.9885.0255.0625.0995.136

Media Choice = SOILAge Range = 0 to 84 monthsRun Mode = ResearchComment = Average IVBA (79.7%)

Concentration355.000355.833356.667357.500358.333359.167360.000

\\herutles%mjps\r>ul>Scalans\EE&SUNSC_8ii>a\iaibiay.Report S 112007025MKE

FIGURE 6PROBABILITY DISTRIBUTION OF BLLsFOR A RANGE OF LEAD CONCENTRATIONSIN SOIL: AVERAGE SCENARIOJACOBSVILLE NEIGHBORHOODSOIL CONTAMINATION SITEEVANSVILLE, INDIANA

CH2WIHJLL -


75

9 12 15 18 21 24 27 30



Run#1234567

% Above4.6684.7514.8344.9195.0035.0895.175

Media Choice = SOILAge Range = 0 to 84 monthsRun Mode = ResearchComment = Maximum IV6A (92%)

Concentration300.000301.667303.333305.000306.667308.333310.000

\\herojles\groups\Publicalior\s\EEiS\JNSC_Bioavailability Report_ES112007025MKE

FIGURE 7PROBABILITY DISTRIBUTION OFBLLs FOR A RANGE OF LEADCONCENTRATION IN SOIL:MAXIMUM SCENARIOJACOBSVILLE NEIGHBORHOODSOIL CONTAMINATION SITEEVANSVILLE, INDIANA

CH2MHILL —'

SECTION 5

Summary

This lead bioavailability study was completed to develop a site-specific soil PRG for lead.Nineteen soil samples were collected from the site for bioavailability analysis. The resultswere evaluated for relative and absolute bioavailability. This evaluation was used tocalculate the range of PRGs for site soil corresponding to the USEPA target level of95 percent of the population with a BLL below 10 |ig/dL. The site-specific PRG range isfrom 306 to 467 mg/kg.

MKE 080170001 5-1

SECTION 6

References

CH2M HILL. 2006a. Final Remedial Investigation Report, Jacobsville Neighborhood SoilContamination Site Evansville, Indiana.

CH2M HILL. 2007b. Final Site-Specific Plans-Addendum, Jacobsville Neighborhood SoilContamination Site Evansville, Indiana.

Indiana Department of Environmental Management (IDEM). 2002. Screening Site Inspection(Combined PA/SSI) for Jacobsville Neighborhood Soil Contamination Site.

U.S. Environmental Protection Agency (USEPA). 1990. The Revised Hazard Ranking System:Qs and As. OSWER Pub. 9320.7-02FS.

U.S. Environmental Protection Agency (USEPA). 1994. Guidance Manual for the IntegratedExposure Uptake Biokinetic Model for Lead in Children. OERR 9285.7-15-1.

U.S. Environmental Protection Agency (USEPA). 1996. Recommendations of the TechnicalReview Workgroup for Lead for an Interim Approach to Assessing Risks Associated withAdult Exposures to Lead in Soil. Technical Review Workgroup for Lead. December.

U.S. Environmental Protection Agency (USEPA). 2005a. Integrated Exposure UptakeBiokinetic Model for Lead in Children, Windows® version (lEUBKwin Version 1.0 Build264). Available online: http://www.epa.gov/superfund/health/contarninants/lead/products.htm#ieubk.

U.S. Environmental Protection Agency (USEPA). 2005b. Quality Assurance Project PlanAddendum B for Jacobsville Neighborhood Soil Contamination RI/FS USEPA Region 5Fund Lead.

U.S. Environmental Protection Agency (USEPA). 2005c. Technical Memorandum #2,Preliminary Site Characterization Summary for Sampling Event Dates: November 29-December 3, 2004.

U.S. Environmental Protection Agency (USEPA). 2005d. Technical Memorandum #4,Preliminary Site Characterization Summary for Sampling Event Dates: April 11-15,2005.

U.S. Environmental Protection Agency (USEPA). 2007. Estimation of Relative Unavailability ofLead in Soil and Soil-like Materials Using In Vivo and In Vitro Methods. OSWER 9285.7-77. May.

U.S. Food and Drug Administration (FDA). 2001. Total Diet Study. U. S. Food and DrugAdministration, Center for Food Safety and Applied Nutrition, Office of Plant and DairyFoods and Beverages. June. Available online: http://www.cfsan.fda.gov/~comm/tdstoc.html.

Weston Solutions, Inc. 2003. Site Assessment Report for Evansville Plating Works.

MKE 080170001 6-1

Appendix AData Quality Evaluation

APPENDIX A

Data Quality Evaluation Report

IntroductionThe object of this data quality evaluation (DQE) report is to assess the data quality ofanalytical results for soil samples collected for the Jacobsville Neighborhood SoilContamination site in Evansville, Indiana. Samples were collected and analyzed to conducta bioavailability study to develop a site-specific soil remediation goal for lead. Individualmethod requirements; guidelines from the U.S. Environmental Protection Agency (USEPA)Contract Laboratory National Functional Guidelines (NFG) for Inorganic Data Review 0uly2004); and the Addendum to the Site-Specific Plans, Jacobsville Neighborhood SoilContamination Site Quality Assurance Project Plan, WA No.015-RICO-B51Z/ContractNo. EP-S5-06-01, October 2007 0acobsville QAPP) were used in this assessment. This reportis intended as a general data quality assessment designed to summarize data issues.

Analytical DataThis DQE report covers 27 soil samples, three field duplicate (FD) samples, and oneequipment blank (EB). Samples were collected September 6,10, and 11,2007. Two methodswere used to analyze the environmental samples and are provided in Table A-l. TheUniversity of Colorado, Boulder, Colorado, performed the analyses. Selected samples wereanalyzed for one or more of the analytes/methods listed in Table A-l.

TABLE A-1Analytical Parameters

Parameter Method Laboratory

Total lead SW3050/SW6020 University of Colorado

Bioavailable lead Leaching Methoda/SW6020 University of Colorado

aSee Final Site-Specific Plans-Addendum, Jacobsville Neighborhood Soil Contamination Site Evansville, Indiana(CH2M HILL 2007), Appendix A, Analytical Standard Operating Procedure for Relative Bioavailability LeachingProcedure, for a complete list of references and a discussion of the method

Soil samples were dried (less than 40 degrees Celsius) and sieved to obtain a less than250 micrometer (um) fraction. Total lead was analyzed on all the samples. Based on the totallead results, selected soil samples were then prepared and analyzed for bioavailable lead.

The assessment of data includes a review of (1) the chain-of-custody (COC) documentation;(2) holding-time compliance; (3) the required quality control (QC) samples at the specifiedfrequencies; (4) flagging for method blanks; (5) laboratory control samples (LCSs); (6) matrixspike (MS) samples; (7) laboratory duplicate samples; and (8) initial and continuingcalibration information.

MKB080170001 A-1

BIOAVAILABILJTY STUDY REPORT

Field samples also were reviewed to ascertain field compliance and data quality issues. Thisincluded a review of EB and FDs.

Data flags were assigned according to the USEPA Contract Laboratory NFG for InorganicData Review 0uly 2004) ana the Jacobsville QAPP. Multiple flags are routinely applied tospecific sample method/matrix/analvte combinations, but there will be only one final flag.A final flag is applied to the data and is the most conservative of the applied validationflags. The final flag also includes matrix and blank sample impacts. No validation flags wereapplied to these data.

The data flags are those listed in NFG and the Jacobsville QAPP and are defined below:

J The analyte was positively identified; the associated numerical value is theapproximate concentration of the analyte in the sample.

R The analyte was rejected due to serious deficiencies in the ability to analyze thesample and meet QC criteria. The presence or absence of the analyte could not beassessed.

U The analyte was analyzed for but was not detected above the reported sampledetection limit.

UJ The analyte was not detected above the reported sample detection limit; however,the reported detection limit is approximate and may or may not represent the actuallimit of quantitation necessary to accurately and precisely measure the analyte in thesample.

FindingsThe overall summaries of the data validation findings are contained in the followingsections.

Holding TimesAll holding time criteria were met.

CalibrationA multiple point initial calibration and continuing calibration verifications standards wereanalyzed at the required frequency with each SW6020 analysis and met method acceptancecriteria.

Method BlanksMethod blanks were analyzed at the required frequency and were free of contamination.

Equipment BlanksAn EB was collected and analyzed at the required frequency. Lead was detected in the EBabove the laboratory water reporting limit; however, all total and bioavailable lead resultswere greater than five times the blank concentration, and no data were qualified.

A.2 MKB080170001

A. DATA QUAUTY EVALUATION REPORT

Field DuplicatesFDs were collected and analyzed at the required frequency, and precision was acceptablefor all FD sets.

Laboratory Control SamplesLCSs and a National Institute of Standards and Technology lead reference standard wereanalyzed as required. All accuracy criteria were met.

Matrix Spike SamplesThe results of MS analyses provide information about the possible influence of the matrix onthe accuracy of the measurements. The field crew designated samples for QC analysis, andthe laboratory also selected additional MS samples. All accuracy criteria were met.

Laboratory Duplicate SamplesThe laboratory selected samples to analyze as duplicate samples to access possible matrixinfluence on the accuracy and precision of the measurements. All accuracy and precisionwere met.

Chain of CustodyCOC sample receipt information was not provided with the analytical data.

Overall AssessmentThe final activity in the data quality evaluation is an assessment of whether the data meetthe data quality objectives. The goal of this assessment is to demonstrate that a sufficientnumber of representative samples were collected and that the resulting analytical data canbe used to support the decisionmaking process. The precision, accuracy, representativeness,completeness, and comparability are addressed in the Jacobsville QAPP. The followingsummary highlights the data evaluation findings for the above defined events:

• The completeness objectives were met for all method/analyte combinations.• No data were qualified because of low-level blank contamination.• The precision and accuracy of the data, as measured by field and laboratory QC

indicators, suggest that the Jacobsville QAPP goals were met.

MKB080170001

Appendix BIEUBK Input and Output Models

CALCULATED BLOOD LEAD AND LEAD UPTAKES:

Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.84612.26012.46212.6539.6568.7878.347

Diet(ug/day)

1.4151.1451.2851.2451.2221.2971.424

Total(ug/day)

9.63914.32014.74114.92911.97511.27610.989

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.24.33.63.2

Water(ug/day)

0.3580.8810.9310.9641.0301.0991.124

Diet ******

Age Diet Intake (ug Pb/day)

.5-11-22-33 14-55-66-7

3.1602.COO2.8702.7402.6102.7402.990

' Drinking Water'

Water Consumption:Age Water (L/day)

.5-1 0.2001-2 0.5002-3 0.5203-4 0.5304-5 0.5505-6 0.5806-7 0.590

Drinking Water Concentration: 4.000 ug Pb/L

iSoil& Dust'

Multiple Source Analysis UsedAverage multiple source concentration: 227.000 ug/g

Mass fraction of outdoor soil to indoor dust conversion factor: 0.700Outdoor airborne lead to indoor household dust lead concentration: 100.000Use alternate indoor dust Pb sources? No

Age Soil (ug Pb/g) House Dust (ug Pb/g)

.5-11-22-33-44-55-66-7

310.000310.000310.000310.000310.000310.000310.000

227.000227.000227.000227.000227.000227.000227.000

' Alternate Intake *****

Age Alternate (ug Pb/day)

.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000

****** Maternal Contribution: Infant Model ******

Maternal Blood Concentration: 2.500 ug Pb/dL


Year Air(ug/day)

.5-1 0.0211-2 0.0342-3 0.0623-4 0.0674-5 0.0675-6 0.0936-7 0.093

Year Soil+Dust(ug/day)

.5-1 7.8081-2 12.2022-3 12.4023-4 12.5914-5 9.6085-6 8.7426-7 8.305

Multiple Runs: NO. 7

Diet(ug/day)

1.4151.1461.2851.2461.2231.2981.424

Total(ug/day)

9.60214.26314.68214.86811.92711.23210.947

Medium:

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Soil (mg/kg)

Water(ug/day)

0.3580.8810.9320.9641.0311.0991.124

INPUT VARIABLES

* Air

Age Cone (ug Pb/mA3)

.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100

Indoor Air Pb Concentration: 30.000 percent of outdoor.

Other Air Parameters:Age Time Ventilation Lung

Outdoors Rate Absorption(hours) (mA3/day) (%)

.5-11-22-33^4-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

Diet1


.5-11-22-33^14-55-66-7

3.1602.6002.8702.7402.6102.7402.990

' Drinking Water *


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


*""* Soil& Dust ******




.5-11-22-3344-55-66-7

308.333308.333308.333308.333308.333308.333308.333

225.833225.833225.833225.833225.833225.833225.833

1 Alternate Intake'


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year Air(ug/day)

.5-1 0.0211-2 0.0342-3 0.0623-4 0.0674-5 0.0675-6 0.0936-7 0.093


.5-1 7.7701-2 12.1432-3 12.3423-4 12.5304-5 9.5595-6 8.6986-7 8.262


Diet(ug/day)

1.4161.1461.2861.2461.2231.2981.425

Total(ug/day)

9.56514.20614.62314.80711.88011.18810.905

Medium:

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.24.33.63.2

Soil (mg/kg)

Water(ug/day)

0.3580.8820.9320.9641.0311.0991.124

INPUT VARIABLES

****** Air ******


.5-1 0.1001-2 0.1002-3 0.1003-4 0.1004-5 0.1005-6 0.1006-7 0.100




.5-11-22-33^14-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

' Diet ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

****** Drinking Water ******


.5-1 0.2001-2 0.5002-3 0.5203-4 0.5304-5 0.5505-6 0.5806-7 0.590


Soil& Dust

Multiple Source Analysis UsedAverage multiple source concentration: 224.667 ug/g /



.5-11-22-33-44-55-66-7

306.667306.667306.667306.667306.667306.667306.667

224.667224.667224.667224.667224.667224.667224.667

' Alternate Intake ******


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000

****** Maternal Contribution: Infant Model'



Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.73212.08512.28212.4689.5118.6548.220

Diet(ug/day)

1.4161.1471.2871.2471.2231.2981.425

Total(ug/day)

9.52814.14914.56314.74611.83211.14410.863

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.14.23.63.1

Water(ug/day)

0.3590.8820.9320.9651.0311.0991.125

Multiple Runs: NO. 5 Medium: Soil (mg/kg)

INPUT VARIABLES

Air'


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Diet'


.5-11-22-33 14-55-66-7

3.1602.6002.8702.7402.6102.7402.990


Water Consumption:Age Water (Uday)

.5-1 0.2001-2 0.5002-3 0.52034 0.5304-5 0.5505-6 0.5806-7 0.590


****** Soil& Dust ******




.5-11-22-33-44-55-66-7

305.000305.000305.000305.000305.000305.000305.000

223.500223.500223.500223.500223.500223.500223.500

****** Alternate Intake ******


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year Air(ug/day)

.5-1 0.0211-2 0.0342-3 0.0623-4 0.0674-5 0.0675-6 0.0936-7 0.093


.5-1 7.6941-2 12.0272-3 12.2223-4 12.4064-5 9.4635-6 8.6096-7 8.178


Diet(ug/day)

1.4171.1471.2871.2471.2241.2981.425

Total(ug/day)

9.49114.09114.50414.68511.78411.10110.821

Medium:

Alternate(ug/aay)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.14.23.53.1

Soil (mg/kg)

Water(ug/day)

0.3590.8830.9330.9651.0311.0991.125

INPUT VARIABLES

****** A if ******


.5-1 0.1001-2 0.1002-3 0.1003-4 0.1004-5 0.1005-6 0.1006-7 0.100




.5-11-22-33^4-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

** Diet'


.5-1 3.1601-2 2.6002-3 2.8703-4 2.7404-5 2.6105-6 2.7406-7 2.990

—** Drinking Water ******

Wafer Consumption:Age Water (L/day)

.5-1 0.2001-2 0.5002-3 0.5203-4 0.5304-5 0.5505-6 0.5806-7 0.590


****** Soil& Dust ******




.5-11-22-33 t4-55-66-7

303.333303.333303.333303.333303.333303.333303.333

222.333222.333222.333222.333222.333222.333222.333

******

Age

.5-11-22-33-44-55-66-7

Alternate Intake

Alternate (ug Pb/day)

0.0000.0000.0000.0000.0000.0000.000






Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.65611.96812.16212.3449.4148.5658.135

Diet(ug/day)

1.4181.1481.2881.2481.2241.2991.425

Total(ug/day)

9.45314.03414.44514.62511.73611.05710.779

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.14.23.53.1

Water(ug/day)

0.3590.8830.9330.9661.0321.1001.125


INPUT VARIABLES

***«*« Air **»*»«Air


.5-11-22-33^4-55-66-7

0.1000.1000.1000.1000.1000.1000.100




32.00032.00032.00032.00032.00032.000

.5-11-22-33-44-55-6

1.0002.0003.0004.0004.0004.000

2.0003.0005.0005.0005.0007.000


.5 1 3.1 601-2 2.6002-3 2.8703 t 2.7404-5 2.6105-6 2.7406-7 2.990



.5-1 0.2001-2 0.5002-3 0.5203-4 0.5304-5 0.5505-6 0.5806-7 0.590


****** Soil& Dust ******


Mass fraction of outdoor soil to indoor dust conversion factor 0.700Outdoor airborne lead to indoor household dust lead concentration: 100.000Use alternate indoor dust Pb sources? No


.5-11-22-33-44-55-66-7

301.667301.667301.667301.667301.667301.667301.667

221.167221.167221.167221.167221.167221.167221.167



.5-11-22-33^t4-55-66-7

0.0000.0000.0000.0000.0000.0000.000


Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.61811.91012.10212.2839.3668.5208.093

Diet(ug/day)

1.4181.1491.2881.2481.2241.2991.426

Total(ug/day)

9.41613.97614.38614.56411.68911.01310.737

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.B5.35.14.23.53.1

Water(ug/day)

0.3590.8840.9340.9661.0321.1001.125


INPUT VARIABLES

' Air ******


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




32.00032.00032.00032.00032.00032.00032.000

.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

****** Drinking Water


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


****** Soil& Dust ******



Age

.5-11-22-33-44-55-66-7

Soil (ug Pb/g) House Dust (ug Pb/g)

300.000300.000300.000300.000300.000300.000300.000

220.000220.000220.000220.000220.000220.000220.000

Alternate Intake *


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000



LEAD MODEL FOR WINDOWS Version 1.0

Model Version: 1.0 Build 264User Name: CH2M HILLDate: 11/14/2007Site Name: JACOBSVILLE NEIGHBORHOODOperable Unit:Run Mode: Research


INPUT VARIABLES

****** AJ- ******


.5-1 0.1001-2 0.1002-3 0.1003-4 0.1004-5 0.1005-6 0.1006-7 0.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Diet ******


.5-11-22-33^4-55-66-7

3.1602.6002.8702.7402.6102.7402.990


Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.82812.23312.43512.6259.6348.7678.328

Diet(ug/day)

1.4151.1451.2851.2461.2221.2981.424

Total(ug/day)

9.62214.29414.71414.90111.95311.25610.969

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.24.33.63.2

Water(ug/day)

0.3580.8810.9310.9641.0301.0991.124


Year

.5-11-22-33^4-55-6&-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.81212.20812.40912.5989.6138.7488.310

Diet(ug/day)

1.4151.1461.2851.2461.2231.2981.424

Total(ug/day)

9.60614.27014.68814.87511.93311.23710.951

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Water(ug/day)

0.3580.8810.9320.9641.0301.0991.124


INPUT VARIABLES

****** A :_. ******


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Qjgf ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990



.5-1 0.2001-2 0.5002-3 0.5203-4 0.5304-5 0.5505-6 0.5806-7 0.590


****** Soil& Dust




.5-11-22-33-44-55-66-7

359.167359.167359.167359.167359.167359.167359.167

261.417261.417261.417261.417261.417261.417261.417



.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year

.5-11-22-33^4-55-66-7

Year

.5-11-22-33^J4-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.79612.18312.38312.5729.5928.7288.291

Diet(ug/day)

1.4151.1461.2861.2461.2231.2981.424

Total(ug/day)

9.59014.24514.66314.84911.91211.21810.933

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Water(ug/day)

0.3580.8810.9320.9641.0311.0991.124


INPUT VARIABLES

Air'


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Difit *****


.5-11-22-33^4-55-66-7

3.1602.6002.8702.7402.6102.7402.990



.5-1 0.2001-2 0.5002-3 0.5203-4 0.5304-5 0.5505-6 0.5806-7 0.590


****** Soil& Dust ******




.5-11-22-33-44-55-66-7

358.333358.333358.333358.333358.333358.333358.333

260.833260.833260.833260.833260.833260.833260.833

* Alternate Intake


.5-11-22-33-4

4-5

5-66-7

0.0000.0000.0000.0000.0000.0000.000




YearI

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air[ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.77912.15812.35812.5459.5718.7098.273

Diet(ug/day}

1.4161.1461.2861.2461.2231.2981.425

Total(ug/day)

9.57414.22014.63714.82311.89211.19910.915

Alternate Water(ug/day) (ug/day)

0.000 0.3580.000 0.8820.000 0.9320.000 0.9640.000 1.0310.000 1.0990.000 1.124

Blood(ug/dL)

5.25.95.45.2

4.33.63.2


INPUT VARIABLES

1 Air **'


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33^4-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

****** Drinking Water"


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


****** Soil& Dust ******




.5-11-22-33 t4-55-66-7

357.500357.500357.500357.500357.500357.500357.500

260.250260.250260.250260.250260.250260.250260.250

Alternate Intake'


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year Air(ug/day)

.5-1 0.0211-2 0.0342-3 0.0623-4 0.0674-5 0.0675-6 0.0936-7 0.093


.5-1 7.7631-2 12.1332-3 12.3323-4 12.5194-5 9.5515-6 8.6906-7 8.255


Diet(ug/day)

1.4161.1461.2861.2471.2231.2981.425

Total(ug/day)

9.55814.19614.61214.79611.87111.18010.897

Medium:

Alternate Water(ug/day) (ug/day)

0.000 0.3580.000 0.8820.000 0.9320.000 0.9640.000 1.0310.000 1.0990.000 1.124

Blood(ug/dL)

5.15.85.45.2

4.23.63.2

Soil (mg/kg)

INPUT VARIABLES

****** Air ******


.5-1 0.1001-2 0.1002-3 0.1003^t 0.1004-5 0.1005-6 0.1006-7 0.100 c




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

' Diet ******


.5-11-22-33^»4-55-66-7

3.1602.6002.8702.7402.6102.7402.990



.5-1 0.2001-2 0.5002-3 0.5203^ 0.5304-5 0.5505-6 0.5806-7 0.590


Soil& Dust




.5-1 356.667 259.6671-2 356.667 259.6672-3 356.667 259.6673-4 356.667 259.6674-5 356.667 259.6675-6 356.667 259.6676-7 356.667 259.667

' Alternate Intake ******


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.73012.08312.28012.4669.5098.6528.218

Diet(ug/day)

1.4161.1471.2871.2471.2231.2981.425

Total(ug/day)

9.52614.14614.56114.74411.83011.14310.861

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.1

4.23.63.1

Water(ug/day)

0.3590.8820.9330.9651.0311.0991.125


INPUT VARIABLES

1 Air *****


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




32.00032.00032.00032.00032.00032.00032.000

.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

****** Drinking Water ****

Water Consumption:Water (L/day)

.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


Soil& Dust




.5-11-22-33-44-55-66-7

355.000355.000355.000355.000355.000355.000355.000

258.500258.500258.500258.500258.500258.500258.500

* Alternate Intake ******


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000






INPUT VARIABLES

Air'


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Diet ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

***** Alternate Intake ******


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.89112.33012.53412.7279.7148.8408.398

Diet(ug/day)

1.4141.1441.2841.2451.2221.2971.424

Total(ug/day)

9.68414.38914.81115.002

12.03211.32911.039

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Water(ug/day)

0.3580.8800.9310.9631.0301.0981.124



Outdoors Rate Absorption(hours) (m*3/day) (%)

.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Diet ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

' Drinking Water


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


****** Soil& Dust



Age

.5-11-22-33-44-55-66-7


475.000475.000475.000475.000475.000475.000475.000

342.500342.500342.500342.500342.500342.500342.500

****** Alternate Intake *—*


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.86612.29112.49512.6869.6828.8118.370

Diet(ug/day)

1.4141.1451.2851.2451.2221.2971.424

Total(ug/day)

9.65914.35114.77214.96112.00111.30011.011

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Water(ug/day)

0.3580.8810.9310.9631.0301.0981.124


INPUT VARIABLES

Air


.5-11-22-33-44-55-6li-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Diet ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

****** Drinking Water **


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


Soil& Dust ******




.5-11-22-33-44-55-66-7

473.333473.333473.333473.333473.333473.333473.333

341.333341.333341.333341.333341.333341.333341.333

****** Alternate Intake *****


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.84112.25312.45512.6459.6508.7818.342

Diet(ug/day)

1.4151.1451.2851.2461.2221.2971.424

Total(ug/day)

9.63514.31314.73314.92111.96911.27110.983

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Water(ug/day)

0.3580.8810.9310.9641.0301.0991.124


INPUT VARIABLES

'Air'


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

***** Diet ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

****** Drinking Water **


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


** Soil& Dust ******




340.167340.167340.167340.167340.167340.167340.167

.5-11-22-33-44-55-66-7

471.667471.667471.667471.667471.667471.667471.667

******

Age

.5-11-22-33-44-55-66-7

Alternate Intake ******


0.0000.0000.0000.0000.0000.0000.000



CALCULATED BLOOD LEAD AND LEAD UPTAKES:******

Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

Soil+Dust(ug/day)

7.81612.21412.41512.6059.6188.7528.314

Diet(ug/day)

1.4151.1461.2851.2461.2221.2981.424

Total(ug/day)

9.61014.27514.69414.881

11.93811.24210.956

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.55.2

4.33.63.2

Water(ug/day)

0.3580.8810.9320.9641.0301.0991.124


INPUT VARIABLES

****** f, :_. ******


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100



Outdoors Rate Absorption(hours) (mA3/day) (%}

.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

' Diet ******


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

****** Drinking Water *****


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


** Soil& Dust ******



Age

.5-11-22-33-44-55-66-7


470.000470.000470.000470.000470.000470.000470.000

339.000339.000339.000339.000339.000339.000339.000

******

Age

.5-11-22-33-44-55-66-7

Alternate Intake ******


0.0000.0000.0000.0000.0000.0000.000

' Maternal Contribution: Infant Model ******



Year Air(ug/day)

.5-1 0.0211-2 0.0342-3 0.0623-4 0.0674-5 0.0675-6 0.0936-7 0.093


.5-1 7.7911-2 12.1762-3 12.3763-4 12.5644-5 9.5865-6 8.7236-7 8.286


Diet(ug/day)

1.4151.1461.2861.2461.2231.2981.424

Total(ug/day)

9.58614.23814.65514.84111.90611.21310.928

Medium:

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.25.95.45.2

4.33.63.2

Soil (mg/kg)

Water(ug/day)

0.3580.8820.9320.9641.0311.0991.124

INPUT VARIABLES

****** Air ****


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

****** Diet'


3.1602.6002.8702.7402.6102.7402.990

Drinking Water'


.5-11-22-33-44-55-66-7

.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


****** Soil& Dust **"*-



Age

.5-11-22-33-44-55-66-7


468.333468.333468.333468.333468.333468.333468.333

337.833337.833337.833337.833337.833337.833337.833

' Alternate Intake **


.5-11-22-33-44-55-66-7

0.0000.0000.0000.0000.0000.0000.000




Year

.5-11-22-33-44-55-66-7

Year

.5-11-22-33-44-55-66-7

Air(ug/day)

0.0210.0340.0620.0670.0670.0930.093

SoikDust(ug/day)

7.76612.13712.33612.5239.5548.6938.258

Diet(ug/day)

1.4161.1461.2861.2471.2231.2981.425

Total(ug/day)

9.56114.20014.61614.80111.87511.18410.900

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.24.23.63.2

Water(ug/day)

0.3580.8820.9320.9641.0311.0991.124


INPUT VARIABLES

****** Air


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100



.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

' Diet'


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

****** Drinking Water **'


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


****** Soil& Dust ******




.5-11-22-33-44-55-66-7

466.667466.667466.667466.667466.667466.667466.667

336.667336.667336.667336.667336.667336.667336.667


Year Air(ug/day)

.5-1 0.0211-2 0.0342-3 0.0623-4 0.0674-5 0.0675-6 0.0936-7 0.093


.5-1 7.7411-2 12.0982-3 12.2963-4 12.4824-5 9.5225-6 8.6646-7 8.230


Diet(ug/day)

1.4161.1471.2871.2471.2231.2981.425

Total(ug/day)

9.53614.16214.57714.76011.84311.15510.873

Medium:

Alternate(ug/day)

0.0000.0000.0000.0000.0000.0000.000

Blood(ug/dL)

5.15.85.45.2

4.23.63.1

Soil (mg/kg)

Water(ug/day)

0.3590.8820.9320.9651.0311.0991.125

INPUT VARIABLES

****** Air ******


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100


Drinking Water **


.5-11-22-33-44-55-66-7

0.2000.5000.5200.5300.5500.5800.590


****** SoilS Dust ******




.5-11-22-33-44-55-66-7

465.000465.000465.000465.000465.000465.000465.000

335.500335.500335.500335.500335.500335.500335.500

" Alternate Intake'


.5-1 0.0001-2 0.0002-3 0.0003-4 0.0004-5 0.0005-6 0.0006-7 0.000






INPUT VARIABLES

* Ajr.....


.5-11-22-33-44-55-66-7

0.1000.1000.1000.1000.1000.1000.100




.5-11-22-33-44-55-66-7

1.0002.0003.0004.0004.0004.0004.000

2.0003.0005.0005.0005.0007.0007.000

32.00032.00032.00032.00032.00032.00032.000

'***** ["tint ******, Diet


.5-11-22-33-44-55-66-7

3.1602.6002.8702.7402.6102.7402.990

Appendix B

Summary of Lead Concentration in Soil Corresponding to EPA's target BLL using the site-specific IVBAJacobsville Neighborhood Soil Contamination Site

Soil Lead ConcentrationCorresponding to EPA's

Target BLLStatistic IVBA RBA ABA (mg Pb/kg soil)

Minimum

Average

Maximum

62.0%

79.7%

92.0%

51.6%

67.2%

78.0%

25.8%

33.6%

39.0%

467

357

306

Note:Blood Lead Level (BLL) as described in the 1994 OSWER Directive of nomore than 5% of children exceeding 10 ug/dL blood lead was used as thetarget level.

Documents

REGION 5 RAC2 · BLL blood lead level FS feasibility study GI gastrointestinal ... ppm parts per million PRG preliminary remediation goal QAPP quality assurance project plan