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Renal Transplantation; where do we stand today? Ioannis Griveas

Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

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Page 1: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Renal Transplantation; where do we stand today?

Ioannis Griveas

Page 3: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 4: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 5: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Background History

Background History

Haemagglutination was the technique first

used – and that continues to be used.

1910 – shown to have inherited

characteristics

1950s represented oligosaccharides

1990 the gene encoding the enzymes

responsible for synthesis of ABO antigen

was cloned.

Page 6: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

ABOi therapy

ANTIBODY REMOVAL

Plasma exchange

Double Filtration Plasma Exchange

Immunoadsorption

ANTIBODY SUPPRESSION

Splenectomy

Anti-CD20

Anti-CD52

IVIg

Page 7: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 8: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 9: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 10: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 11: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 12: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 13: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 14: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 15: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 16: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 17: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 18: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 19: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 20: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 21: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

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Page 22: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 23: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 24: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 25: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 26: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 27: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 28: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 29: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 30: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 31: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 32: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 33: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 34: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 35: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Renal Transplantation; where to we stand today?

Ioannis Griveas

Page 36: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Renal Transplantation; where to we stand today?

Ioannis Griveas

Page 37: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Renal Transplantation; where to we stand today?

Ioannis Griveas

Page 38: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Renal Transplantation; where to we stand today?

Ioannis Griveas

Page 39: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown

Renal Transplantation; where to we stand today?

Ioannis Griveas

Page 40: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 41: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 42: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 43: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 44: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 45: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 46: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 47: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 48: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 49: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 50: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 51: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 52: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 53: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 54: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown
Page 55: Renal Transplantation; where do we stand today? · Background History Background History Haemagglutination was the technique first used –and that continues to be used. 1910 –shown